ENSG00000166452

1 Isoform Switch

Summary Plot

Only the isoforms with fraction > 5% are shown below.

  • Note:

    • About the Coding Potential: Please check the spreadsheet in the “Results” tag to confirm the coding potential. The above figure only show the predicted coding potential. The “gene_biotype” in the result spreadsheet is from the database record. Therefore, if you find conflicts between “gene_biotype” and “codingPotential”, please trust the “gene_biotype”.

    • Notes on IDR and IDR_w_binding: As the prediction of Intrinsically Disordered Regions (IDR) and Intrinsically Disordered Binding Regions (IDBR) are done by two different tools we require two things to annotate the Intrinsically Disordered Binding Regions (IDBR). Firstly the IDBR (predicted by ANCHOR2) must be a region of at least 15 amino acids (after the smoothing). Secondly the fraction of the IDBR which overlaps the IDR predictions (done by IUPred3, again after smoothing) must be at least 80%. When that is the case the IDR type will be annotated as “IDR_w_binding_region” instead of just “IDR”. The current default parameters have not been rigorously tested and should be considered experimental.

    • For the function of any other domain, please Click HERE to search it through Pfam database.

Results

isoform_id gene_id condition_1 condition_2 gene_name gene_biotype iso_biotype gene_overall_mean gene_value_1 gene_value_2 gene_stderr_1 gene_stderr_2 gene_log2_fold_change iso_overall_mean iso_value_1 iso_value_2 iso_stderr_1 iso_stderr_2 iso_log2_fold_change IF_overall IF1 IF2 dIF isoform_switch_q_value gene_switch_q_value PTC codingPotential
ENST00000299576 ENSG00000166452 No_inf pgKDN_inf AKIP1 protein_coding protein_coding 37.0741 50.09732 33.16828 1.114608 1.201188 -0.5947824 9.982948 7.281760 10.3940752 4.9623891 4.1808431 0.5128097 0.29571667 0.145050 0.305375 0.160325 0.80371536 0.02467108 FALSE TRUE
ENST00000309377 ENSG00000166452 No_inf pgKDN_inf AKIP1 protein_coding protein_coding 37.0741 50.09732 33.16828 1.114608 1.201188 -0.5947824 17.311031 22.982810 15.1665829 2.1503077 2.8120046 -0.5993358 0.46935833 0.457050 0.455575 -0.001475 1.00000000 0.02467108 FALSE TRUE
ENST00000396648 ENSG00000166452 No_inf pgKDN_inf AKIP1 protein_coding protein_coding 37.0741 50.09732 33.16828 1.114608 1.201188 -0.5947824 2.669344 5.616477 2.3915560 3.2717373 2.3915560 -1.2282624 0.06385000 0.114825 0.076725 -0.038100 0.86106044 0.02467108 FALSE TRUE
ENST00000525005 ENSG00000166452 No_inf pgKDN_inf AKIP1 protein_coding protein_coding 37.0741 50.09732 33.16828 1.114608 1.201188 -0.5947824 1.856852 4.229845 0.4151977 1.4209825 0.4151977 -3.3178060 0.04440833 0.086300 0.013325 -0.072975 0.36824867 0.02467108 FALSE TRUE
MSTRG.4423.2 ENSG00000166452 No_inf pgKDN_inf AKIP1 protein_coding   37.0741 50.09732 33.16828 1.114608 1.201188 -0.5947824 1.421711 1.403155 2.8619762 0.9027615 2.8619762 1.0231236 0.04018333 0.028725 0.091825 0.063100 0.85600277 0.02467108 FALSE TRUE
MSTRG.4423.7 ENSG00000166452 No_inf pgKDN_inf AKIP1 protein_coding   37.0741 50.09732 33.16828 1.114608 1.201188 -0.5947824 2.269881 6.809643 0.0000000 2.4955512 0.0000000 -9.4135525 0.04490000 0.134700 0.000000 -0.134700 0.02467108 0.02467108   FALSE
  • Note:
    • The comparisons made can be identified as “from ‘condition_1’ to ‘condition_2’”, meaning ‘condition_1’ is considered the ground state and ‘condition_2’ the changed state. This also means that a positive dIF value indicates that the isoform usage is increased in ‘condition_2’ compared to ‘condition_1’. Since the ‘isoformFeatures’ entry is the most relevant part of the switchAnalyzeRlist object, the most-used standard methods have also been implemented to work directly on isoformFeatures.

Help

Please Click HERE to learn more details about the results of IsoformSwitchAnalyzeR.

2 Differential Exon Usage

Counts

All exons whithin this gene region are shown and numbering below.

Expression

All exons whithin this gene region are shown and numbering below.

Splicing

All exons whithin this gene region are shown and numbering below.

Transcripts

All isoforms whithin this gene region are shown below.

Results

groupID featureID exonBaseMean dispersion pvalue padj seqnames start end width strand pgKDN.inf No.inf log2fold_No.inf_pgKDN.inf
ENSG00000166452 E001 0.0000000       11 8911139 8911141 3 +      
ENSG00000166452 E002 0.1170040 0.0117333089 0.316392451   11 8911142 8911153 12 + 0.119 0.000 -9.333
ENSG00000166452 E003 0.3614886 0.0166422263 0.317286158   11 8911154 8911188 35 + 0.212 0.076 -1.732
ENSG00000166452 E004 0.3614886 0.0166422263 0.317286158   11 8911189 8911191 3 + 0.212 0.076 -1.732
ENSG00000166452 E005 0.7242670 0.0140309549 0.153316579 0.41787833 11 8911192 8911197 6 + 0.354 0.140 -1.732
ENSG00000166452 E006 1.4751907 0.0116419055 0.776293955 0.91413093 11 8911198 8911198 1 + 0.411 0.367 -0.246
ENSG00000166452 E007 2.6019526 0.0055532661 0.685960287 0.87030696 11 8911199 8911214 16 + 0.506 0.563 0.268
ENSG00000166452 E008 5.0832793 0.0028275199 0.647423110 0.85101796 11 8911215 8911223 9 + 0.734 0.787 0.216
ENSG00000166452 E009 1.7501369 0.0087164160 0.198259660 0.47967596 11 8911224 8911287 64 + 0.289 0.490 1.143
ENSG00000166452 E010 3.2452454 0.0140181201 0.127064051 0.37787122 11 8911288 8911337 50 + 0.461 0.681 1.005
ENSG00000166452 E011 3.5085542 0.0044518819 0.023643791 0.14059584 11 8911338 8911354 17 + 0.411 0.730 1.470
ENSG00000166452 E012 5.3600488 0.0141107507 0.114808241 0.35717972 11 8911355 8911442 88 + 0.650 0.850 0.809
ENSG00000166452 E013 2.7305008 0.0084858569 0.580089221 0.81265830 11 8911443 8911443 1 + 0.506 0.585 0.368
ENSG00000166452 E014 12.1291173 0.0013092432 0.698221625 0.87685909 11 8911444 8911464 21 + 1.081 1.113 0.116
ENSG00000166452 E015 35.6320434 0.0033558019 0.280583341 0.57391511 11 8911465 8911614 150 + 1.582 1.525 -0.197
ENSG00000166452 E016 24.6795838 0.0006224375 0.010107835 0.08084769 11 8911615 8911671 57 + 1.482 1.333 -0.516
ENSG00000166452 E017 18.1129794 0.0008918390 0.326501522 0.61894396 11 8912453 8912533 81 + 1.306 1.239 -0.236
ENSG00000166452 E018 41.1027097 0.0004033530 0.420496483 0.69979811 11 8914826 8914930 105 + 1.630 1.593 -0.125
ENSG00000166452 E019 39.6993043 0.0004598086 0.837214585 0.94167653 11 8917287 8917367 81 + 1.586 1.595 0.032
ENSG00000166452 E020 11.7574821 0.0012074692 0.000613139 0.01021911 11 8917368 8918119 752 + 0.864 1.178 1.156
ENSG00000166452 E021 116.5837755 0.0001956307 0.703270415 0.87921641 11 8919337 8920084 748 + 2.047 2.056 0.029

Help

Please Click HERE to learn more details about the results from DEXseq.