ENSG00000166562

1 Isoform Switch

Summary Plot

Only the isoforms with fraction > 5% are shown below.

  • Note:

    • About the Coding Potential: Please check the spreadsheet in the “Results” tag to confirm the coding potential. The above figure only show the predicted coding potential. The “gene_biotype” in the result spreadsheet is from the database record. Therefore, if you find conflicts between “gene_biotype” and “codingPotential”, please trust the “gene_biotype”.

    • Notes on IDR and IDR_w_binding: As the prediction of Intrinsically Disordered Regions (IDR) and Intrinsically Disordered Binding Regions (IDBR) are done by two different tools we require two things to annotate the Intrinsically Disordered Binding Regions (IDBR). Firstly the IDBR (predicted by ANCHOR2) must be a region of at least 15 amino acids (after the smoothing). Secondly the fraction of the IDBR which overlaps the IDR predictions (done by IUPred3, again after smoothing) must be at least 80%. When that is the case the IDR type will be annotated as “IDR_w_binding_region” instead of just “IDR”. The current default parameters have not been rigorously tested and should be considered experimental.

    • For the function of any other domain, please Click HERE to search it through Pfam database.

Results

isoform_id gene_id condition_1 condition_2 gene_name gene_biotype iso_biotype gene_overall_mean gene_value_1 gene_value_2 gene_stderr_1 gene_stderr_2 gene_log2_fold_change iso_overall_mean iso_value_1 iso_value_2 iso_stderr_1 iso_stderr_2 iso_log2_fold_change IF_overall IF1 IF2 dIF isoform_switch_q_value gene_switch_q_value PTC codingPotential
ENST00000587834 ENSG00000166562 No_inf pgKDN_inf SEC11C protein_coding protein_coding 70.444 42.81492 87.49576 2.526794 4.437324 1.030928 61.165053 30.649201 76.783179 2.7158846 1.344955 1.324658 0.845625 0.713300 0.883175 0.169875 0.049450846 0.005759267 FALSE TRUE
ENST00000591406 ENSG00000166562 No_inf pgKDN_inf SEC11C protein_coding retained_intron 70.444 42.81492 87.49576 2.526794 4.437324 1.030928 3.119984 7.029807 1.337725 0.5374476 1.337725 -2.385010 0.064075 0.166825 0.013450 -0.153375 0.005759267 0.005759267   FALSE
  • Note:
    • The comparisons made can be identified as “from ‘condition_1’ to ‘condition_2’”, meaning ‘condition_1’ is considered the ground state and ‘condition_2’ the changed state. This also means that a positive dIF value indicates that the isoform usage is increased in ‘condition_2’ compared to ‘condition_1’. Since the ‘isoformFeatures’ entry is the most relevant part of the switchAnalyzeRlist object, the most-used standard methods have also been implemented to work directly on isoformFeatures.

Help

Please Click HERE to learn more details about the results of IsoformSwitchAnalyzeR.

2 Differential Exon Usage

Counts

All exons whithin this gene region are shown and numbering below.

Expression

All exons whithin this gene region are shown and numbering below.

Splicing

All exons whithin this gene region are shown and numbering below.

Transcripts

All isoforms whithin this gene region are shown below.

Results

groupID featureID exonBaseMean dispersion pvalue padj seqnames start end width strand pgKDN.inf No.inf log2fold_No.inf_pgKDN.inf
ENSG00000166562 E001 1.0983737 0.0105843722 0.5229547649 0.776420907 18 59139866 59139874 9 + 0.274 0.374 0.638
ENSG00000166562 E002 2.1873980 0.0064202417 0.6726645176 0.864445963 18 59139875 59139883 9 + 0.467 0.530 0.308
ENSG00000166562 E003 2.3145343 0.0061669569 0.4722819576 0.739606710 18 59139884 59139887 4 + 0.467 0.572 0.500
ENSG00000166562 E004 3.4056697 0.0051411351 0.5694994354 0.806426922 18 59139888 59139892 5 + 0.600 0.677 0.332
ENSG00000166562 E005 4.1400392 0.0034834370 0.3919463804 0.677018834 18 59139893 59139898 6 + 0.654 0.762 0.445
ENSG00000166562 E006 26.6803506 0.0005679577 0.2204494092 0.507392073 18 59139899 59140035 137 + 1.448 1.378 -0.241
ENSG00000166562 E007 0.0000000       18 59140036 59140051 16 +      
ENSG00000166562 E008 0.4995438 0.0151383546 0.0991604679   18 59146983 59147294 312 + 0.070 0.306 2.544
ENSG00000166562 E009 0.6244813 0.0166990383 0.0371883795 0.185645877 18 59147295 59148012 718 + 0.070 0.374 2.959
ENSG00000166562 E010 41.1454820 0.0004093697 0.0843230348 0.299893080 18 59149513 59149622 110 + 1.633 1.554 -0.269
ENSG00000166562 E011 40.6660633 0.0003652760 0.9444141764 0.984572234 18 59152536 59152612 77 + 1.600 1.605 0.017
ENSG00000166562 E012 48.5460460 0.0049379638 0.8978439584 0.966256592 18 59152613 59152685 73 + 1.677 1.676 -0.003
ENSG00000166562 E013 3.0631981 0.0047953488 0.0679017514 0.262938904 18 59152686 59153361 676 + 0.492 0.735 1.075
ENSG00000166562 E014 1.3877049 0.0101151999 0.0000926431 0.002231627 18 59155605 59155687 83 + 0.070 0.645 4.281
ENSG00000166562 E015 58.5941568 0.0002936088 0.9304742481 0.979681759 18 59155688 59155807 120 + 1.757 1.756 -0.005
ENSG00000166562 E016 3.1399126 0.0045377908 0.7242796921 0.889237199 18 59155808 59157311 1504 + 0.619 0.572 -0.210
ENSG00000166562 E017 29.6604493 0.0005107120 0.8238313113 0.936071754 18 59157608 59157665 58 + 1.464 1.477 0.047
ENSG00000166562 E018 39.9275096 0.0039050430 0.9107180835 0.971742519 18 59158632 59158832 201 + 1.592 1.597 0.018

Help

Please Click HERE to learn more details about the results from DEXseq.