ENSG00000166734

1 Isoform Switch

Summary Plot

Only the isoforms with fraction > 5% are shown below.

  • Note:

    • About the Coding Potential: Please check the spreadsheet in the “Results” tag to confirm the coding potential. The above figure only show the predicted coding potential. The “gene_biotype” in the result spreadsheet is from the database record. Therefore, if you find conflicts between “gene_biotype” and “codingPotential”, please trust the “gene_biotype”.

    • Notes on IDR and IDR_w_binding: As the prediction of Intrinsically Disordered Regions (IDR) and Intrinsically Disordered Binding Regions (IDBR) are done by two different tools we require two things to annotate the Intrinsically Disordered Binding Regions (IDBR). Firstly the IDBR (predicted by ANCHOR2) must be a region of at least 15 amino acids (after the smoothing). Secondly the fraction of the IDBR which overlaps the IDR predictions (done by IUPred3, again after smoothing) must be at least 80%. When that is the case the IDR type will be annotated as “IDR_w_binding_region” instead of just “IDR”. The current default parameters have not been rigorously tested and should be considered experimental.

    • For the function of any other domain, please Click HERE to search it through Pfam database.

Results

isoform_id gene_id condition_1 condition_2 gene_name gene_biotype iso_biotype gene_overall_mean gene_value_1 gene_value_2 gene_stderr_1 gene_stderr_2 gene_log2_fold_change iso_overall_mean iso_value_1 iso_value_2 iso_stderr_1 iso_stderr_2 iso_log2_fold_change IF_overall IF1 IF2 dIF isoform_switch_q_value gene_switch_q_value PTC codingPotential
ENST00000299957 ENSG00000166734 No_inf pgKDN_inf GOLM2 protein_coding protein_coding 50.1047 57.8995 49.9594 1.377544 1.441855 -0.212755 10.120316 9.317612 11.361497 3.1414497 1.7163358 0.2858425 0.20900833 0.163250 0.227775 0.064525 0.83389824 0.02191576 FALSE TRUE
ENST00000345795 ENSG00000166734 No_inf pgKDN_inf GOLM2 protein_coding protein_coding 50.1047 57.8995 49.9594 1.377544 1.441855 -0.212755 13.938778 9.918517 19.688248 1.3005937 2.1184720 0.9884172 0.29278333 0.172200 0.395175 0.222975 0.02191576 0.02191576 FALSE TRUE
ENST00000558847 ENSG00000166734 No_inf pgKDN_inf GOLM2 protein_coding protein_coding 50.1047 57.8995 49.9594 1.377544 1.441855 -0.212755 2.299089 3.996955 0.438133 1.4749287 0.4381330 -3.1605072 0.04161667 0.067475 0.008600 -0.058875 0.33008111 0.02191576 FALSE FALSE
ENST00000561305 ENSG00000166734 No_inf pgKDN_inf GOLM2 protein_coding protein_coding 50.1047 57.8995 49.9594 1.377544 1.441855 -0.212755 20.018479 29.056204 16.294210 0.9072366 0.9407765 -0.8340981 0.38786667 0.502425 0.326100 -0.176325 0.02547236 0.02191576   FALSE
  • Note:
    • The comparisons made can be identified as “from ‘condition_1’ to ‘condition_2’”, meaning ‘condition_1’ is considered the ground state and ‘condition_2’ the changed state. This also means that a positive dIF value indicates that the isoform usage is increased in ‘condition_2’ compared to ‘condition_1’. Since the ‘isoformFeatures’ entry is the most relevant part of the switchAnalyzeRlist object, the most-used standard methods have also been implemented to work directly on isoformFeatures.

Help

Please Click HERE to learn more details about the results of IsoformSwitchAnalyzeR.

2 Differential Exon Usage

Counts

All exons whithin this gene region are shown and numbering below.

Expression

All exons whithin this gene region are shown and numbering below.

Splicing

All exons whithin this gene region are shown and numbering below.

Transcripts

All isoforms whithin this gene region are shown below.

Results

groupID featureID exonBaseMean dispersion pvalue padj seqnames start end width strand pgKDN.inf No.inf log2fold_No.inf_pgKDN.inf
ENSG00000166734 E001 0.0000000       15 44288719 44288728 10 +      
ENSG00000166734 E002 0.0000000       15 44288729 44288730 2 +      
ENSG00000166734 E003 0.0000000       15 44288731 44288732 2 +      
ENSG00000166734 E004 0.0000000       15 44288733 44288737 5 +      
ENSG00000166734 E005 0.9878864 0.0114442832 4.428505e-01 7.180374e-01 15 44288738 44288759 22 + 0.236 0.352 0.791
ENSG00000166734 E006 1.1147403 0.0111364092 2.866767e-01 5.801733e-01 15 44288760 44288763 4 + 0.236 0.397 1.054
ENSG00000166734 E007 7.9111925 0.0064970967 2.595468e-01 5.520308e-01 15 44288764 44288904 141 + 1.006 0.888 -0.439
ENSG00000166734 E008 12.0853601 0.0128298989 4.429709e-01 7.181217e-01 15 44288905 44289104 200 + 1.153 1.078 -0.268
ENSG00000166734 E009 8.1448838 0.0076103486 1.184411e-01 3.635472e-01 15 44289105 44289158 54 + 1.035 0.874 -0.603
ENSG00000166734 E010 25.8878242 0.0215673991 4.119351e-02 1.969904e-01 15 44289159 44289356 198 + 1.508 1.336 -0.594
ENSG00000166734 E011 0.7537898 0.1593544315 1.229930e-01 3.711467e-01 15 44307238 44308536 1299 + 0.094 0.352 2.376
ENSG00000166734 E012 0.1176306 0.0117383352 5.634631e-01   15 44319407 44319553 147 + 0.094 0.000 -11.587
ENSG00000166734 E013 15.2218775 0.0016101856 1.528195e-01 4.170083e-01 15 44322965 44323019 55 + 1.262 1.153 -0.388
ENSG00000166734 E014 10.2395372 0.0014874423 3.805167e-01 6.670172e-01 15 44328685 44328699 15 + 1.090 1.010 -0.291
ENSG00000166734 E015 18.1231516 0.0008190798 6.577413e-01 8.568749e-01 15 44328700 44328787 88 + 1.268 1.295 0.093
ENSG00000166734 E016 26.0827988 0.0005717275 1.469470e-01 4.080021e-01 15 44331988 44332078 91 + 1.475 1.388 -0.298
ENSG00000166734 E017 12.1263821 0.0022855330 1.898657e-02 1.226961e-01 15 44337763 44337763 1 + 1.208 1.010 -0.714
ENSG00000166734 E018 34.4509562 0.0008951530 3.001673e-02 1.630420e-01 15 44337764 44337907 144 + 1.604 1.490 -0.388
ENSG00000166734 E019 0.2530140 0.2365380711 2.797200e-01   15 44338210 44338236 27 + 0.000 0.176 10.956
ENSG00000166734 E020 30.8051077 0.0074231801 7.161998e-01 8.855258e-01 15 44338237 44338317 81 + 1.515 1.490 -0.084
ENSG00000166734 E021 0.3644125 0.2077618509 6.591819e-01   15 44345875 44346149 275 + 0.170 0.097 -0.947
ENSG00000166734 E022 1.5062830 0.0092015371 1.389229e-02 9.949099e-02 15 44348543 44348918 376 + 0.170 0.543 2.376
ENSG00000166734 E023 32.7124541 0.0050267455 3.185814e-01 6.112617e-01 15 44379690 44379788 99 + 1.557 1.497 -0.206
ENSG00000166734 E024 23.1848317 0.0114417226 3.952170e-01 6.799895e-01 15 44380806 44380863 58 + 1.415 1.351 -0.221
ENSG00000166734 E025 19.6976478 0.0233777557 1.007164e-01 3.312622e-01 15 44380864 44380976 113 + 1.386 1.236 -0.524
ENSG00000166734 E026 0.0000000       15 44382079 44382229 151 +      
ENSG00000166734 E027 2.0826761 0.0366838987 7.629222e-01 9.074708e-01 15 44402887 44403050 164 + 0.466 0.511 0.224
ENSG00000166734 E028 0.5067834 0.1791761754 6.542559e-02 2.576043e-01 15 44403051 44403054 4 + 0.000 0.300 12.014
ENSG00000166734 E029 0.6155377 0.1873441860 6.464757e-01 8.503871e-01 15 44406330 44406883 554 + 0.170 0.243 0.639
ENSG00000166734 E030 0.8695952 0.0140105286 2.305551e-01 5.190056e-01 15 44409519 44409847 329 + 0.170 0.352 1.376
ENSG00000166734 E031 0.0000000       15 44413336 44413436 101 +      
ENSG00000166734 E032 124.6109450 0.0001474580 5.053951e-01 7.642138e-01 15 44413437 44414513 1077 + 2.109 2.089 -0.068
ENSG00000166734 E033 287.3599837 0.0001005304 8.264109e-10 7.188975e-08 15 44414514 44415758 1245 + 2.416 2.498 0.274

Help

Please Click HERE to learn more details about the results from DEXseq.