ENSG00000166848

1 Isoform Switch

Summary Plot

Only the isoforms with fraction > 5% are shown below.

  • Note:

    • About the Coding Potential: Please check the spreadsheet in the “Results” tag to confirm the coding potential. The above figure only show the predicted coding potential. The “gene_biotype” in the result spreadsheet is from the database record. Therefore, if you find conflicts between “gene_biotype” and “codingPotential”, please trust the “gene_biotype”.

    • Notes on IDR and IDR_w_binding: As the prediction of Intrinsically Disordered Regions (IDR) and Intrinsically Disordered Binding Regions (IDBR) are done by two different tools we require two things to annotate the Intrinsically Disordered Binding Regions (IDBR). Firstly the IDBR (predicted by ANCHOR2) must be a region of at least 15 amino acids (after the smoothing). Secondly the fraction of the IDBR which overlaps the IDR predictions (done by IUPred3, again after smoothing) must be at least 80%. When that is the case the IDR type will be annotated as “IDR_w_binding_region” instead of just “IDR”. The current default parameters have not been rigorously tested and should be considered experimental.

    • For the function of any other domain, please Click HERE to search it through Pfam database.

Results

isoform_id gene_id condition_1 condition_2 gene_name gene_biotype iso_biotype gene_overall_mean gene_value_1 gene_value_2 gene_stderr_1 gene_stderr_2 gene_log2_fold_change iso_overall_mean iso_value_1 iso_value_2 iso_stderr_1 iso_stderr_2 iso_log2_fold_change IF_overall IF1 IF2 dIF isoform_switch_q_value gene_switch_q_value PTC codingPotential
ENST00000300086 ENSG00000166848 No_inf pgKDN_inf TERF2IP protein_coding protein_coding 62.57828 54.32457 68.30519 0.6414256 1.190568 0.3303361 43.84944 30.36485 48.89260 1.491871 1.316456 0.6870340 0.6927167 0.558425 0.7159 0.157475 0.02514132 0.02514132 FALSE TRUE
ENST00000569234 ENSG00000166848 No_inf pgKDN_inf TERF2IP protein_coding nonsense_mediated_decay 62.57828 54.32457 68.30519 0.6414256 1.190568 0.3303361 18.59590 23.66124 19.41259 1.098947 1.206820 -0.2853995 0.3049167 0.436025 0.2841 -0.151925 0.08250724 0.02514132 FALSE TRUE
  • Note:
    • The comparisons made can be identified as “from ‘condition_1’ to ‘condition_2’”, meaning ‘condition_1’ is considered the ground state and ‘condition_2’ the changed state. This also means that a positive dIF value indicates that the isoform usage is increased in ‘condition_2’ compared to ‘condition_1’. Since the ‘isoformFeatures’ entry is the most relevant part of the switchAnalyzeRlist object, the most-used standard methods have also been implemented to work directly on isoformFeatures.

Help

Please Click HERE to learn more details about the results of IsoformSwitchAnalyzeR.

2 Differential Exon Usage

Counts

All exons whithin this gene region are shown and numbering below.

Expression

All exons whithin this gene region are shown and numbering below.

Splicing

All exons whithin this gene region are shown and numbering below.

Transcripts

All isoforms whithin this gene region are shown below.

Results

groupID featureID exonBaseMean dispersion pvalue padj seqnames start end width strand pgKDN.inf No.inf log2fold_No.inf_pgKDN.inf
ENSG00000166848 E001 0.7428026 1.401828e-02 0.329787055 0.6222186 16 75647773 75647790 18 + 0.164 0.311 1.193
ENSG00000166848 E002 79.7662400 1.956068e-04 0.227037172 0.5153195 16 75647791 75648395 605 + 1.925 1.887 -0.126
ENSG00000166848 E003 11.8900906 1.614970e-02 0.083352936 0.2975220 16 75648396 75648552 157 + 1.182 1.018 -0.591
ENSG00000166848 E004 0.3706447 2.218146e-01 0.555929113   16 75648553 75648682 130 + 0.090 0.183 1.193
ENSG00000166848 E005 36.4334660 4.135497e-04 0.654341995 0.8548745 16 75654273 75654397 125 + 1.562 1.585 0.077
ENSG00000166848 E006 31.0716604 1.594096e-03 0.380118916 0.6666884 16 75656207 75656231 25 + 1.528 1.482 -0.159
ENSG00000166848 E007 52.0290004 2.956968e-04 0.840612316 0.9428146 16 75656232 75656341 110 + 1.728 1.721 -0.024
ENSG00000166848 E008 383.8653705 9.478496e-05 0.173328549 0.4465394 16 75656342 75657432 1091 + 2.578 2.592 0.046
ENSG00000166848 E009 0.0000000       16 75732868 75732991 124 +      
ENSG00000166848 E010 0.0000000       16 75733323 75734228 906 +      
ENSG00000166848 E011 0.1268540 1.234163e-02 0.471801916   16 75760050 75760140 91 + 0.000 0.101 9.760
ENSG00000166848 E012 1.0156453 1.162339e-02 0.001183808 0.0170260 16 75760833 75761872 1040 + 0.000 0.491 12.699

Help

Please Click HERE to learn more details about the results from DEXseq.