ENSG00000166887

1 Isoform Switch

Summary Plot

Only the isoforms with fraction > 5% are shown below.

  • Note:

    • About the Coding Potential: Please check the spreadsheet in the “Results” tag to confirm the coding potential. The above figure only show the predicted coding potential. The “gene_biotype” in the result spreadsheet is from the database record. Therefore, if you find conflicts between “gene_biotype” and “codingPotential”, please trust the “gene_biotype”.

    • Notes on IDR and IDR_w_binding: As the prediction of Intrinsically Disordered Regions (IDR) and Intrinsically Disordered Binding Regions (IDBR) are done by two different tools we require two things to annotate the Intrinsically Disordered Binding Regions (IDBR). Firstly the IDBR (predicted by ANCHOR2) must be a region of at least 15 amino acids (after the smoothing). Secondly the fraction of the IDBR which overlaps the IDR predictions (done by IUPred3, again after smoothing) must be at least 80%. When that is the case the IDR type will be annotated as “IDR_w_binding_region” instead of just “IDR”. The current default parameters have not been rigorously tested and should be considered experimental.

    • For the function of any other domain, please Click HERE to search it through Pfam database.

Results

isoform_id gene_id condition_1 condition_2 gene_name gene_biotype iso_biotype gene_overall_mean gene_value_1 gene_value_2 gene_stderr_1 gene_stderr_2 gene_log2_fold_change iso_overall_mean iso_value_1 iso_value_2 iso_stderr_1 iso_stderr_2 iso_log2_fold_change IF_overall IF1 IF2 dIF isoform_switch_q_value gene_switch_q_value PTC codingPotential
ENST00000318006 ENSG00000166887 No_inf pgKDN_inf VPS39 protein_coding protein_coding 30.19793 43.2823 23.95801 1.284213 0.1650684 -0.8530005 13.586253 13.377104 14.528515 0.5179522 1.0013490 0.119036 0.4910250 0.309400 0.607250 0.29785 0.003006601 0.003006601 FALSE TRUE
ENST00000568029 ENSG00000166887 No_inf pgKDN_inf VPS39 protein_coding retained_intron 30.19793 43.2823 23.95801 1.284213 0.1650684 -0.8530005 3.371177 5.843509 2.065761 1.1064206 0.2385694 -1.495661 0.1048917 0.133650 0.086250 -0.04740 0.797365239 0.003006601   FALSE
MSTRG.9372.5 ENSG00000166887 No_inf pgKDN_inf VPS39 protein_coding   30.19793 43.2823 23.95801 1.284213 0.1650684 -0.8530005 6.489280 12.083571 2.811833 1.1642529 1.8605603 -2.099536 0.1953750 0.279175 0.116475 -0.16270 0.380782551 0.003006601 FALSE TRUE
  • Note:
    • The comparisons made can be identified as “from ‘condition_1’ to ‘condition_2’”, meaning ‘condition_1’ is considered the ground state and ‘condition_2’ the changed state. This also means that a positive dIF value indicates that the isoform usage is increased in ‘condition_2’ compared to ‘condition_1’. Since the ‘isoformFeatures’ entry is the most relevant part of the switchAnalyzeRlist object, the most-used standard methods have also been implemented to work directly on isoformFeatures.

Help

Please Click HERE to learn more details about the results of IsoformSwitchAnalyzeR.

2 Differential Exon Usage

Counts

All exons whithin this gene region are shown and numbering below.

Expression

All exons whithin this gene region are shown and numbering below.

Splicing

All exons whithin this gene region are shown and numbering below.

Transcripts

All isoforms whithin this gene region are shown below.

Results

groupID featureID exonBaseMean dispersion pvalue padj seqnames start end width strand pgKDN.inf No.inf log2fold_No.inf_pgKDN.inf
ENSG00000166887 E001 0.0000000       15 42158701 42158704 4 -      
ENSG00000166887 E002 0.9901810 1.084760e-01 9.987474e-01 1.0000000000 15 42158705 42158712 8 - 0.292 0.287 -0.039
ENSG00000166887 E003 1.1174433 7.627519e-02 8.220870e-01 0.9354890763 15 42158713 42158715 3 - 0.292 0.327 0.225
ENSG00000166887 E004 1.4986960 2.050563e-02 3.897901e-01 0.6753395593 15 42158716 42158716 1 - 0.292 0.429 0.810
ENSG00000166887 E005 291.3784609 8.265728e-05 3.285807e-05 0.0009327195 15 42158717 42160430 1714 - 2.404 2.467 0.210
ENSG00000166887 E006 53.3908427 1.150445e-03 8.891460e-01 0.9630138084 15 42160431 42160753 323 - 1.721 1.714 -0.024
ENSG00000166887 E007 19.0389897 7.324723e-04 9.833653e-01 0.9986902635 15 42160754 42160829 76 - 1.284 1.282 -0.008
ENSG00000166887 E008 2.3869528 2.011163e-02 4.975313e-02 0.2200397742 15 42160830 42161473 644 - 0.292 0.601 1.640
ENSG00000166887 E009 0.4987572 2.239973e-02 6.424750e-01   15 42161474 42161590 117 - 0.121 0.193 0.810
ENSG00000166887 E010 14.1124825 9.900178e-04 6.837667e-01 0.8690995871 15 42161682 42161718 37 - 1.140 1.172 0.113
ENSG00000166887 E011 8.6133628 2.275869e-03 3.156295e-01 0.6084863865 15 42161719 42161723 5 - 1.026 0.929 -0.360
ENSG00000166887 E012 14.2123651 1.880723e-03 9.273950e-01 0.9783937655 15 42161724 42161773 50 - 1.160 1.166 0.023
ENSG00000166887 E013 0.1272623 1.233780e-02 1.000000e+00   15 42162028 42162031 4 - 0.000 0.074 10.297
ENSG00000166887 E014 29.9642027 1.110256e-02 3.648507e-01 0.6533270790 15 42162032 42162166 135 - 1.510 1.449 -0.210
ENSG00000166887 E015 0.3809703 3.584494e-02 2.589267e-01   15 42162167 42162331 165 - 0.000 0.193 11.721
ENSG00000166887 E016 31.2069088 5.164067e-04 2.645942e-01 0.5577314558 15 42162332 42162481 150 - 1.527 1.466 -0.209
ENSG00000166887 E017 0.4992614 1.570824e-02 6.409277e-01   15 42162482 42162672 191 - 0.121 0.193 0.810
ENSG00000166887 E018 18.5880754 1.329418e-03 4.597993e-01 0.7314206664 15 42163350 42163395 46 - 1.239 1.291 0.182
ENSG00000166887 E019 0.2536433 1.597334e-02 4.884679e-01   15 42163561 42163625 65 - 0.000 0.138 11.247
ENSG00000166887 E020 20.8584044 7.875357e-04 1.446199e-01 0.4048211391 15 42163626 42163728 103 - 1.255 1.353 0.343
ENSG00000166887 E021 21.6155509 3.453453e-03 8.818099e-02 0.3079483094 15 42164358 42164486 129 - 1.255 1.374 0.416
ENSG00000166887 E022 0.7534081 1.501356e-02 2.873529e-01 0.5807355211 15 42164487 42164604 118 - 0.121 0.287 1.547
ENSG00000166887 E023 0.8784070 1.234925e-02 1.905747e-01 0.4697750069 15 42164605 42164784 180 - 0.121 0.327 1.810
ENSG00000166887 E024 1.3765990 8.348859e-02 2.164159e-01 0.5025180064 15 42164785 42164889 105 - 0.215 0.429 1.395
ENSG00000166887 E025 1.7428664 8.777100e-03 5.152386e-01 0.7714204388 15 42164890 42164995 106 - 0.358 0.458 0.547
ENSG00000166887 E026 16.3465077 2.165928e-03 5.040239e-01 0.7633482109 15 42164996 42165113 118 - 1.188 1.238 0.176
ENSG00000166887 E027 3.8963906 4.570209e-03 2.996345e-03 0.0344928612 15 42165114 42165717 604 - 0.358 0.782 1.980
ENSG00000166887 E028 16.8066450 1.460910e-03 9.669591e-01 0.9933545130 15 42165718 42165816 99 - 1.231 1.233 0.007
ENSG00000166887 E029 14.5358209 1.031413e-03 3.070984e-01 0.6003279337 15 42166159 42166232 74 - 1.222 1.143 -0.281
ENSG00000166887 E030 16.0013472 9.605008e-04 1.523147e-01 0.4162215447 15 42166563 42166649 87 - 1.277 1.172 -0.373
ENSG00000166887 E031 23.1926606 5.810841e-04 4.015432e-01 0.6846711354 15 42166772 42166913 142 - 1.398 1.345 -0.184
ENSG00000166887 E032 21.4705568 6.667247e-04 4.599083e-03 0.0466797192 15 42167394 42167537 144 - 1.441 1.260 -0.626
ENSG00000166887 E033 16.8082970 8.004695e-04 1.221916e-02 0.0915442446 15 42169724 42169850 127 - 1.339 1.161 -0.627
ENSG00000166887 E034 6.9106845 2.094154e-03 7.190737e-01 0.8868074864 15 42169851 42169866 16 - 0.905 0.867 -0.147
ENSG00000166887 E035 0.8714168 1.395617e-02 6.443582e-01 0.8494113335 15 42169867 42169892 26 - 0.215 0.287 0.547
ENSG00000166887 E036 0.0000000       15 42173637 42173722 86 -      
ENSG00000166887 E037 14.8119493 4.684844e-03 6.334227e-01 0.8431982260 15 42173723 42173852 130 - 1.205 1.166 -0.140
ENSG00000166887 E038 15.9249788 1.044034e-03 5.436905e-01 0.7905390369 15 42178218 42178338 121 - 1.239 1.193 -0.162
ENSG00000166887 E039 18.5858392 1.046201e-03 8.978709e-02 0.3112396154 15 42178450 42178570 121 - 1.345 1.228 -0.410
ENSG00000166887 E040 12.2018544 2.656132e-02 8.687233e-02 0.3055278279 15 42178571 42179103 533 - 0.970 1.160 0.694
ENSG00000166887 E041 5.8727284 2.622743e-03 4.899636e-02 0.2181958448 15 42180041 42180291 251 - 0.655 0.889 0.935
ENSG00000166887 E042 4.1150920 4.872171e-03 1.248659e-01 0.3746046037 15 42184192 42184516 325 - 0.552 0.754 0.869
ENSG00000166887 E043 21.2023904 1.459307e-03 1.278196e-03 0.0180797899 15 42184517 42184700 184 - 1.450 1.242 -0.725
ENSG00000166887 E044 11.9237636 1.305527e-03 1.383797e-01 0.3957458185 15 42187271 42187363 93 - 1.169 1.045 -0.446
ENSG00000166887 E045 9.8658314 1.414932e-03 5.743951e-01 0.8094328468 15 42187758 42187856 99 - 1.051 0.999 -0.190
ENSG00000166887 E046 6.7120374 2.261726e-03 8.739106e-03 0.0734052252 15 42189114 42189208 95 - 1.026 0.754 -1.038
ENSG00000166887 E047 5.1687465 2.704583e-03 4.351914e-01 0.7121026166 15 42191125 42191167 43 - 0.830 0.740 -0.360
ENSG00000166887 E048 0.2444846 1.618312e-02 6.774175e-01   15 42191168 42191170 3 - 0.121 0.074 -0.775
ENSG00000166887 E049 1.4806962 8.999503e-03 7.387492e-01 0.8964012327 15 42191261 42191495 235 - 0.415 0.364 -0.290
ENSG00000166887 E050 8.2964013 1.602656e-03 6.595234e-01 0.8579116487 15 42191496 42191560 65 - 0.922 0.965 0.161
ENSG00000166887 E051 0.2352613 2.361945e-01 1.427807e-01   15 42192066 42192098 33 - 0.215 0.000 -12.318
ENSG00000166887 E052 7.8996326 1.765787e-03 7.273879e-01 0.8911464605 15 42199896 42199961 66 - 0.954 0.919 -0.133
ENSG00000166887 E053 13.6955948 3.249754e-02 1.427364e-02 0.1015782185 15 42208081 42208307 227 - 1.299 1.038 -0.930

Help

Please Click HERE to learn more details about the results from DEXseq.