ENSG00000166938

1 Isoform Switch

Summary Plot

Only the isoforms with fraction > 5% are shown below.

  • Note:

    • About the Coding Potential: Please check the spreadsheet in the “Results” tag to confirm the coding potential. The above figure only show the predicted coding potential. The “gene_biotype” in the result spreadsheet is from the database record. Therefore, if you find conflicts between “gene_biotype” and “codingPotential”, please trust the “gene_biotype”.

    • Notes on IDR and IDR_w_binding: As the prediction of Intrinsically Disordered Regions (IDR) and Intrinsically Disordered Binding Regions (IDBR) are done by two different tools we require two things to annotate the Intrinsically Disordered Binding Regions (IDBR). Firstly the IDBR (predicted by ANCHOR2) must be a region of at least 15 amino acids (after the smoothing). Secondly the fraction of the IDBR which overlaps the IDR predictions (done by IUPred3, again after smoothing) must be at least 80%. When that is the case the IDR type will be annotated as “IDR_w_binding_region” instead of just “IDR”. The current default parameters have not been rigorously tested and should be considered experimental.

    • For the function of any other domain, please Click HERE to search it through Pfam database.

Results

isoform_id gene_id condition_1 condition_2 gene_name gene_biotype iso_biotype gene_overall_mean gene_value_1 gene_value_2 gene_stderr_1 gene_stderr_2 gene_log2_fold_change iso_overall_mean iso_value_1 iso_value_2 iso_stderr_1 iso_stderr_2 iso_log2_fold_change IF_overall IF1 IF2 dIF isoform_switch_q_value gene_switch_q_value PTC codingPotential
ENST00000319212 ENSG00000166938 No_inf pgKDN_inf DIS3L protein_coding protein_coding 6.324071 9.169696 4.479797 0.8927286 0.5146183 -1.031796 2.7272613 2.5238124 3.5539872 1.2559735 0.2801338 0.4921824 0.48975000 0.262000 0.808475 0.546475 0.091299360 0.001907717 FALSE TRUE
ENST00000530537 ENSG00000166938 No_inf pgKDN_inf DIS3L protein_coding nonsense_mediated_decay 6.324071 9.169696 4.479797 0.8927286 0.5146183 -1.031796 1.8298261 4.4272524 0.0000000 1.2349585 0.0000000 -8.7935228 0.24163333 0.516100 0.000000 -0.516100 0.001907717 0.001907717 FALSE TRUE
ENST00000532293 ENSG00000166938 No_inf pgKDN_inf DIS3L protein_coding protein_coding_CDS_not_defined 6.324071 9.169696 4.479797 0.8927286 0.5146183 -1.031796 0.3675602 0.3757865 0.2593007 0.3757865 0.2593007 -0.5185845 0.06171667 0.037825 0.058800 0.020975 0.933033837 0.001907717 FALSE FALSE
ENST00000564945 ENSG00000166938 No_inf pgKDN_inf DIS3L protein_coding retained_intron 6.324071 9.169696 4.479797 0.8927286 0.5146183 -1.031796 0.1580276 0.4740828 0.0000000 0.4740828 0.0000000 -5.5971820 0.01765833 0.052975 0.000000 -0.052975 0.972756414 0.001907717 FALSE FALSE
ENST00000568874 ENSG00000166938 No_inf pgKDN_inf DIS3L protein_coding protein_coding_CDS_not_defined 6.324071 9.169696 4.479797 0.8927286 0.5146183 -1.031796 0.7219579 1.0832383 0.1927773 0.6791491 0.1927773 -2.4306400 0.10011667 0.103375 0.032550 -0.070825 0.812082342 0.001907717   FALSE
  • Note:
    • The comparisons made can be identified as “from ‘condition_1’ to ‘condition_2’”, meaning ‘condition_1’ is considered the ground state and ‘condition_2’ the changed state. This also means that a positive dIF value indicates that the isoform usage is increased in ‘condition_2’ compared to ‘condition_1’. Since the ‘isoformFeatures’ entry is the most relevant part of the switchAnalyzeRlist object, the most-used standard methods have also been implemented to work directly on isoformFeatures.

Help

Please Click HERE to learn more details about the results of IsoformSwitchAnalyzeR.

2 Differential Exon Usage

Counts

All exons whithin this gene region are shown and numbering below.

Expression

All exons whithin this gene region are shown and numbering below.

Splicing

All exons whithin this gene region are shown and numbering below.

Transcripts

All isoforms whithin this gene region are shown below.

Results

groupID featureID exonBaseMean dispersion pvalue padj seqnames start end width strand pgKDN.inf No.inf log2fold_No.inf_pgKDN.inf
ENSG00000166938 E001 0.0000000       15 66293217 66293290 74 +      
ENSG00000166938 E002 0.0000000       15 66293291 66293306 16 +      
ENSG00000166938 E003 0.0000000       15 66293307 66293336 30 +      
ENSG00000166938 E004 0.0000000       15 66293337 66293367 31 +      
ENSG00000166938 E005 0.0000000       15 66293501 66293567 67 +      
ENSG00000166938 E006 0.1176306 0.0117552953 0.25908723   15 66293568 66293595 28 + 0.129 0.000 -11.272
ENSG00000166938 E007 0.7174955 0.0152556964 0.01321058 0.09630975 15 66293596 66293638 43 + 0.437 0.069 -3.332
ENSG00000166938 E008 1.6951859 0.0095653753 0.02091717 0.13042157 15 66293639 66293735 97 + 0.616 0.270 -1.858
ENSG00000166938 E009 0.1271363 0.0124178074 1.00000000   15 66293832 66293842 11 + 0.000 0.069 11.252
ENSG00000166938 E010 0.2457744 0.0165583364 0.59500572   15 66293843 66293916 74 + 0.129 0.069 -1.010
ENSG00000166938 E011 0.1186381 0.0120016722 0.25886531   15 66293917 66294058 142 + 0.129 0.000 -13.640
ENSG00000166938 E012 0.1271363 0.0124178074 1.00000000   15 66294059 66294174 116 + 0.000 0.069 11.252
ENSG00000166938 E013 0.3723465 0.0166205741 1.00000000   15 66294175 66294448 274 + 0.129 0.129 -0.010
ENSG00000166938 E014 3.3257149 0.0051003080 0.44130434 0.71682074 15 66294988 66295096 109 + 0.683 0.575 -0.469
ENSG00000166938 E015 2.4295004 0.0097158640 0.01749247 0.11597282 15 66295097 66295141 45 + 0.713 0.377 -1.595
ENSG00000166938 E016 0.1176306 0.0117552953 0.25908723   15 66306762 66306819 58 + 0.129 0.000 -13.641
ENSG00000166938 E017 0.1176306 0.0117552953 0.25908723   15 66306820 66306823 4 + 0.129 0.000 -13.641
ENSG00000166938 E018 1.8127583 0.0224165709 0.01100891 0.08560475 15 66306824 66306896 73 + 0.651 0.270 -2.010
ENSG00000166938 E019 1.4583506 0.1195985411 0.12013708 0.36646533 15 66306897 66306952 56 + 0.535 0.270 -1.495
ENSG00000166938 E020 4.0691717 0.0046743184 0.49247499 0.75462089 15 66308709 66308844 136 + 0.742 0.648 -0.388
ENSG00000166938 E021 4.4626027 0.0039566975 0.96425499 0.99245321 15 66311724 66311900 177 + 0.713 0.711 -0.010
ENSG00000166938 E022 0.0000000       15 66311901 66311901 1 +      
ENSG00000166938 E023 1.2424085 0.0119380021 0.80934214 0.92963602 15 66314039 66314117 79 + 0.310 0.344 0.213
ENSG00000166938 E024 0.0000000       15 66315036 66315078 43 +      
ENSG00000166938 E025 3.1880373 0.0155454776 0.09666714 0.32378870 15 66315079 66315215 137 + 0.742 0.511 -1.010
ENSG00000166938 E026 5.9263166 0.0047192143 0.39232279 0.67732902 15 66318449 66318618 170 + 0.881 0.778 -0.400
ENSG00000166938 E027 3.3222881 0.0058318714 0.24973815 0.54072169 15 66320571 66320649 79 + 0.713 0.555 -0.688
ENSG00000166938 E028 3.8363065 0.0037710321 0.82987485 0.93834361 15 66320650 66320732 83 + 0.683 0.648 -0.147
ENSG00000166938 E029 7.2479067 0.0020629415 0.05779440 0.24055282 15 66322687 66322934 248 + 0.742 0.943 0.782
ENSG00000166938 E030 3.8655134 0.0039950787 0.34466126 0.63582277 15 66323493 66323585 93 + 0.577 0.696 0.514
ENSG00000166938 E031 15.5508232 0.0009380564 0.15637440 0.42264581 15 66325831 66326364 534 + 1.119 1.218 0.353
ENSG00000166938 E032 0.2356421 0.0160511096 0.08340470   15 66326365 66326561 197 + 0.229 0.000 -14.511
ENSG00000166938 E033 2.8545271 0.0050240401 0.74330832 0.89846685 15 66328970 66328996 27 + 0.535 0.575 0.183
ENSG00000166938 E034 5.3411479 0.0032937269 0.63160834 0.84198619 15 66328997 66329124 128 + 0.742 0.791 0.197
ENSG00000166938 E035 3.6124633 0.0043166286 0.48406237 0.74835027 15 66329221 66329279 59 + 0.577 0.665 0.383
ENSG00000166938 E036 7.3179851 0.0019378711 0.81226526 0.93093565 15 66329280 66329399 120 + 0.881 0.898 0.064
ENSG00000166938 E037 0.4981279 0.0153295978 0.74943496   15 66329400 66329548 149 + 0.129 0.181 0.575
ENSG00000166938 E038 1.3749268 0.0570803947 0.30215046 0.59533784 15 66329613 66330024 412 + 0.229 0.407 1.160
ENSG00000166938 E039 9.2192540 0.0018712780 0.21139297 0.49635475 15 66331875 66332020 146 + 0.900 1.013 0.423
ENSG00000166938 E040 12.9210869 0.0010764469 0.38694766 0.67282337 15 66332736 66332910 175 + 1.071 1.133 0.226
ENSG00000166938 E041 35.4923014 0.0004839715 0.37076080 0.65898850 15 66333004 66334206 1203 + 1.509 1.542 0.113

Help

Please Click HERE to learn more details about the results from DEXseq.