ENSG00000167460

1 Isoform Switch

Summary Plot

Only the isoforms with fraction > 5% are shown below.

  • Note:

    • About the Coding Potential: Please check the spreadsheet in the “Results” tag to confirm the coding potential. The above figure only show the predicted coding potential. The “gene_biotype” in the result spreadsheet is from the database record. Therefore, if you find conflicts between “gene_biotype” and “codingPotential”, please trust the “gene_biotype”.

    • Notes on IDR and IDR_w_binding: As the prediction of Intrinsically Disordered Regions (IDR) and Intrinsically Disordered Binding Regions (IDBR) are done by two different tools we require two things to annotate the Intrinsically Disordered Binding Regions (IDBR). Firstly the IDBR (predicted by ANCHOR2) must be a region of at least 15 amino acids (after the smoothing). Secondly the fraction of the IDBR which overlaps the IDR predictions (done by IUPred3, again after smoothing) must be at least 80%. When that is the case the IDR type will be annotated as “IDR_w_binding_region” instead of just “IDR”. The current default parameters have not been rigorously tested and should be considered experimental.

    • For the function of any other domain, please Click HERE to search it through Pfam database.

Results

isoform_id gene_id condition_1 condition_2 gene_name gene_biotype iso_biotype gene_overall_mean gene_value_1 gene_value_2 gene_stderr_1 gene_stderr_2 gene_log2_fold_change iso_overall_mean iso_value_1 iso_value_2 iso_stderr_1 iso_stderr_2 iso_log2_fold_change IF_overall IF1 IF2 dIF isoform_switch_q_value gene_switch_q_value PTC codingPotential
ENST00000588032 ENSG00000167460 No_inf pgKDN_inf TPM4 protein_coding nonsense_mediated_decay 362.9356 217.8546 448.6555 3.787783 3.614156 1.042208 49.55067 47.25914 59.28745 6.506800 5.639844 0.3270714 0.14908333 0.215600 0.13205 -0.083550 1.548712e-01 2.728665e-06 TRUE FALSE
ENST00000643579 ENSG00000167460 No_inf pgKDN_inf TPM4 protein_coding protein_coding 362.9356 217.8546 448.6555 3.787783 3.614156 1.042208 226.92434 98.45207 297.70146 6.550409 11.737164 1.5962748 0.59600000 0.451125 0.66315 0.212025 2.728665e-06 2.728665e-06 FALSE TRUE
ENST00000653979 ENSG00000167460 No_inf pgKDN_inf TPM4 protein_coding nonsense_mediated_decay 362.9356 217.8546 448.6555 3.787783 3.614156 1.042208 38.17470 30.53633 40.98655 6.530327 14.597673 0.4245034 0.11190833 0.141600 0.09200 -0.049600 8.468598e-01 2.728665e-06 FALSE TRUE
ENST00000659595 ENSG00000167460 No_inf pgKDN_inf TPM4 protein_coding nonsense_mediated_decay 362.9356 217.8546 448.6555 3.787783 3.614156 1.042208 25.40392 14.82434 31.40287 2.948802 7.376620 1.0824148 0.06973333 0.068450 0.06980 0.001350 1.000000e+00 2.728665e-06 FALSE TRUE
  • Note:
    • The comparisons made can be identified as “from ‘condition_1’ to ‘condition_2’”, meaning ‘condition_1’ is considered the ground state and ‘condition_2’ the changed state. This also means that a positive dIF value indicates that the isoform usage is increased in ‘condition_2’ compared to ‘condition_1’. Since the ‘isoformFeatures’ entry is the most relevant part of the switchAnalyzeRlist object, the most-used standard methods have also been implemented to work directly on isoformFeatures.

Help

Please Click HERE to learn more details about the results of IsoformSwitchAnalyzeR.

2 Differential Exon Usage

Counts

All exons whithin this gene region are shown and numbering below.

Expression

All exons whithin this gene region are shown and numbering below.

Splicing

All exons whithin this gene region are shown and numbering below.

Transcripts

All isoforms whithin this gene region are shown below.

Results

groupID featureID exonBaseMean dispersion pvalue padj seqnames start end width strand pgKDN.inf No.inf log2fold_No.inf_pgKDN.inf
ENSG00000167460 E001 0.0000000       19 16067021 16067306 286 +      
ENSG00000167460 E002 0.0000000       19 16067534 16067537 4 +      
ENSG00000167460 E003 0.0000000       19 16067538 16067668 131 +      
ENSG00000167460 E004 0.0000000       19 16067669 16067699 31 +      
ENSG00000167460 E005 0.0000000       19 16067700 16067732 33 +      
ENSG00000167460 E006 0.0000000       19 16067733 16067738 6 +      
ENSG00000167460 E007 0.0000000       19 16067739 16067962 224 +      
ENSG00000167460 E008 0.0000000       19 16075679 16075679 1 +      
ENSG00000167460 E009 0.0000000       19 16075680 16075709 30 +      
ENSG00000167460 E010 0.0000000       19 16075710 16075875 166 +      
ENSG00000167460 E011 0.0000000       19 16075941 16076046 106 +      
ENSG00000167460 E012 0.0000000       19 16076047 16076072 26 +      
ENSG00000167460 E013 0.0000000       19 16076073 16076090 18 +      
ENSG00000167460 E014 0.0000000       19 16076091 16076172 82 +      
ENSG00000167460 E015 0.0000000       19 16076173 16076438 266 +      
ENSG00000167460 E016 0.0000000       19 16076439 16076448 10 +      
ENSG00000167460 E017 0.0000000       19 16076449 16076455 7 +      
ENSG00000167460 E018 0.0000000       19 16076456 16076475 20 +      
ENSG00000167460 E019 0.0000000       19 16076476 16076488 13 +      
ENSG00000167460 E020 0.0000000       19 16076489 16076494 6 +      
ENSG00000167460 E021 0.0000000       19 16076495 16076498 4 +      
ENSG00000167460 E022 0.0000000       19 16076499 16076520 22 +      
ENSG00000167460 E023 0.0000000       19 16076521 16076560 40 +      
ENSG00000167460 E024 0.0000000       19 16076561 16076644 84 +      
ENSG00000167460 E025 0.0000000       19 16076645 16076697 53 +      
ENSG00000167460 E026 0.0000000       19 16077016 16077020 5 +      
ENSG00000167460 E027 0.0000000       19 16077021 16077130 110 +      
ENSG00000167460 E028 6.7341065 0.0020298969 1.254532e-08 8.775864e-07 19 16077957 16078149 193 + 0.549 1.153 2.379
ENSG00000167460 E029 33.2984373 0.0210709655 8.417282e-18 1.868221e-15 19 16078852 16079501 650 + 1.113 1.829 2.471
ENSG00000167460 E030 35.2596350 0.0004535405 1.657455e-38 1.375280e-35 19 16079502 16080317 816 + 1.159 1.845 2.363
ENSG00000167460 E031 9.9667983 0.0013528145 6.325916e-12 7.433158e-10 19 16080318 16080442 125 + 0.682 1.311 2.355
ENSG00000167460 E032 7.2683661 0.0019608970 2.240591e-12 2.784425e-10 19 16080443 16080551 109 + 0.476 1.218 2.960
ENSG00000167460 E033 9.1810049 0.0015000938 3.391891e-08 2.180432e-06 19 16080552 16080764 213 + 0.729 1.243 1.924
ENSG00000167460 E034 8.8590365 0.0211697335 2.927523e-09 2.308377e-07 19 16080765 16080914 150 + 0.611 1.275 2.532
ENSG00000167460 E035 7.5918353 0.0017991444 9.628768e-09 6.878384e-07 19 16080915 16081019 105 + 0.611 1.191 2.237
ENSG00000167460 E036 5.2166560 0.0078170667 2.223002e-05 6.739484e-04 19 16081020 16081075 56 + 0.526 1.024 2.022
ENSG00000167460 E037 11.2242178 0.0195894271 3.963207e-10 3.653874e-08 19 16081076 16081343 268 + 0.714 1.364 2.407
ENSG00000167460 E038 2.5140312 0.0121798866 8.813871e-06 3.060962e-04 19 16081344 16081440 97 + 0.189 0.821 3.367
ENSG00000167460 E039 0.2539903 0.0159680309 9.684010e-02   19 16081441 16081448 8 + 0.000 0.220 11.585
ENSG00000167460 E040 1.7335520 0.0078922756 3.143542e-02 1.673184e-01 19 16081449 16081538 90 + 0.280 0.599 1.713
ENSG00000167460 E041 0.7441544 0.0137243803 1.259420e-01 3.762354e-01 19 16081539 16081543 5 + 0.134 0.366 1.865
ENSG00000167460 E042 6.1894257 0.0304596801 5.396284e-04 9.268891e-03 19 16081544 16081912 369 + 0.630 1.063 1.695
ENSG00000167460 E043 110.1525857 0.0001397518 4.686589e-03 4.730797e-02 19 16081913 16082046 134 + 2.060 1.977 -0.280
ENSG00000167460 E044 0.2448930 0.0161775843 6.440320e-01   19 16086294 16086422 129 + 0.072 0.124 0.865
ENSG00000167460 E045 184.7183668 0.0005642284 5.627256e-03 5.396041e-02 19 16086423 16086540 118 + 2.278 2.211 -0.223
ENSG00000167460 E046 131.7723895 0.0001208747 3.100293e-02 1.658183e-01 19 16088027 16088058 32 + 2.129 2.072 -0.191
ENSG00000167460 E047 176.4948518 0.0012159416 3.493659e-03 3.873114e-02 19 16088059 16088097 39 + 2.262 2.184 -0.262
ENSG00000167460 E048 0.2438580 0.0161238159 6.438108e-01   19 16088098 16088149 52 + 0.072 0.124 0.865
ENSG00000167460 E049 0.3533378 0.0157570426 2.790480e-01   19 16088150 16088259 110 + 0.189 0.000 -11.727
ENSG00000167460 E050 1.7152698 0.0078331955 2.759578e-01 5.693405e-01 19 16088260 16088618 359 + 0.356 0.520 0.865
ENSG00000167460 E051 0.7434668 0.0132301209 1.256536e-01 3.757903e-01 19 16088619 16088718 100 + 0.134 0.366 1.865
ENSG00000167460 E052 0.4816076 0.0152725911 6.838075e-01   19 16088719 16088849 131 + 0.189 0.124 -0.720
ENSG00000167460 E053 0.7285169 0.1228492076 9.385659e-01 9.822569e-01 19 16088850 16089044 195 + 0.237 0.220 -0.136
ENSG00000167460 E054 252.3828547 0.0045116014 6.633929e-04 1.088182e-02 19 16089045 16089120 76 + 2.427 2.315 -0.373
ENSG00000167460 E055 3.3686777 0.0420282527 2.947248e-04 5.724050e-03 19 16089121 16089653 533 + 0.356 0.881 2.379
ENSG00000167460 E056 0.7170221 0.1617519192 3.785925e-01 6.655695e-01 19 16092891 16093039 149 + 0.280 0.124 -1.457
ENSG00000167460 E057 1.0797733 0.0111994042 3.898610e-01 6.753850e-01 19 16093040 16093132 93 + 0.356 0.220 -0.943
ENSG00000167460 E058 1.3301480 0.1185832235 9.472704e-01 9.860370e-01 19 16093133 16093535 403 + 0.356 0.366 0.059
ENSG00000167460 E059 231.0435522 0.0004333970 1.790489e-07 9.863964e-06 19 16093536 16093598 63 + 2.390 2.276 -0.381
ENSG00000167460 E060 131.0351665 0.0001410042 1.346222e-03 1.882965e-02 19 16093684 16093753 70 + 2.136 2.049 -0.292
ENSG00000167460 E061 1.9617099 0.0553890884 2.867521e-01 5.802297e-01 19 16095264 16095357 94 + 0.389 0.561 0.865
ENSG00000167460 E062 1.4891021 0.0096444115 3.106054e-02 1.660606e-01 19 16095358 16095591 234 + 0.237 0.561 1.865
ENSG00000167460 E063 0.9886395 0.0147048073 1.276298e-01 3.787391e-01 19 16095592 16095775 184 + 0.189 0.423 1.602
ENSG00000167460 E064 0.6171744 0.0147045354 2.717033e-01 5.654600e-01 19 16095776 16095893 118 + 0.134 0.299 1.450
ENSG00000167460 E065 3.9941243 0.0794248954 4.268056e-04 7.711669e-03 19 16095894 16096744 851 + 0.389 0.951 2.449
ENSG00000167460 E066 7.5338390 0.0024904497 3.127456e-05 8.943595e-04 19 16099667 16101263 1597 + 0.714 1.132 1.589
ENSG00000167460 E067 113.1385487 0.0006046444 1.758860e-01 4.499932e-01 19 16101264 16101409 146 + 2.057 2.017 -0.133
ENSG00000167460 E068 858.6203690 0.0001521788 2.271392e-03 2.812068e-02 19 16101410 16102059 650 + 2.930 2.901 -0.098
ENSG00000167460 E069 1345.0942483 0.0002693785 1.718087e-02 1.146681e-01 19 16102060 16103002 943 + 3.106 3.128 0.073

Help

Please Click HERE to learn more details about the results from DEXseq.