ENSG00000167468

1 Isoform Switch

Summary Plot

Only the isoforms with fraction > 5% are shown below.

  • Note:

    • About the Coding Potential: Please check the spreadsheet in the “Results” tag to confirm the coding potential. The above figure only show the predicted coding potential. The “gene_biotype” in the result spreadsheet is from the database record. Therefore, if you find conflicts between “gene_biotype” and “codingPotential”, please trust the “gene_biotype”.

    • Notes on IDR and IDR_w_binding: As the prediction of Intrinsically Disordered Regions (IDR) and Intrinsically Disordered Binding Regions (IDBR) are done by two different tools we require two things to annotate the Intrinsically Disordered Binding Regions (IDBR). Firstly the IDBR (predicted by ANCHOR2) must be a region of at least 15 amino acids (after the smoothing). Secondly the fraction of the IDBR which overlaps the IDR predictions (done by IUPred3, again after smoothing) must be at least 80%. When that is the case the IDR type will be annotated as “IDR_w_binding_region” instead of just “IDR”. The current default parameters have not been rigorously tested and should be considered experimental.

    • For the function of any other domain, please Click HERE to search it through Pfam database.

Results

isoform_id gene_id condition_1 condition_2 gene_name gene_biotype iso_biotype gene_overall_mean gene_value_1 gene_value_2 gene_stderr_1 gene_stderr_2 gene_log2_fold_change iso_overall_mean iso_value_1 iso_value_2 iso_stderr_1 iso_stderr_2 iso_log2_fold_change IF_overall IF1 IF2 dIF isoform_switch_q_value gene_switch_q_value PTC codingPotential
ENST00000354171 ENSG00000167468 No_inf pgKDN_inf GPX4 protein_coding protein_coding 295.2515 281.4887 293.9508 8.807986 9.554975 0.06249584 55.11738 34.5668 67.43474 5.122232 10.93083 0.9639015 0.1868000 0.124225 0.232875 0.108650 0.18983857 0.04911706   FALSE
ENST00000611653 ENSG00000167468 No_inf pgKDN_inf GPX4 protein_coding protein_coding 295.2515 281.4887 293.9508 8.807986 9.554975 0.06249584 203.56660 212.7347 187.36264 10.521567 13.96797 -0.1832127 0.6906333 0.754650 0.635775 -0.118875 0.04911706 0.04911706   FALSE
  • Note:
    • The comparisons made can be identified as “from ‘condition_1’ to ‘condition_2’”, meaning ‘condition_1’ is considered the ground state and ‘condition_2’ the changed state. This also means that a positive dIF value indicates that the isoform usage is increased in ‘condition_2’ compared to ‘condition_1’. Since the ‘isoformFeatures’ entry is the most relevant part of the switchAnalyzeRlist object, the most-used standard methods have also been implemented to work directly on isoformFeatures.

Help

Please Click HERE to learn more details about the results of IsoformSwitchAnalyzeR.

2 Differential Exon Usage

Counts

All exons whithin this gene region are shown and numbering below.

Expression

All exons whithin this gene region are shown and numbering below.

Splicing

All exons whithin this gene region are shown and numbering below.

Transcripts

All isoforms whithin this gene region are shown below.

Results

groupID featureID exonBaseMean dispersion pvalue padj seqnames start end width strand pgKDN.inf No.inf log2fold_No.inf_pgKDN.inf
ENSG00000167468 E001 0.0000000       19 1103994 1104007 14 +      
ENSG00000167468 E002 2.5621713 5.887060e-03 0.407327116 0.68982807 19 1104008 1104051 44 + 0.608 0.494 -0.530
ENSG00000167468 E003 9.1035525 1.660773e-03 0.564123225 0.80337511 19 1104052 1104066 15 + 0.973 1.027 0.198
ENSG00000167468 E004 22.3201512 6.316733e-04 0.920492708 0.97521456 19 1104067 1104072 6 + 1.370 1.364 -0.020
ENSG00000167468 E005 67.0572116 9.780834e-04 0.774307565 0.91329493 19 1104073 1104127 55 + 1.837 1.827 -0.036
ENSG00000167468 E006 3.0656210 6.254960e-03 0.997755453 1.00000000 19 1104415 1104705 291 + 0.608 0.608 0.000
ENSG00000167468 E007 14.5821843 1.002714e-03 0.868809423 0.95487065 19 1104706 1104929 224 + 1.198 1.186 -0.043
ENSG00000167468 E008 0.7528434 3.432892e-02 0.119091207 0.36473720 19 1105152 1105155 4 + 0.099 0.338 2.206
ENSG00000167468 E009 1.3518905 4.023912e-02 0.878217802 0.95862342 19 1105156 1105185 30 + 0.357 0.382 0.148
ENSG00000167468 E010 123.7948685 1.371309e-04 0.694356856 0.87522677 19 1105186 1105252 67 + 2.089 2.100 0.036
ENSG00000167468 E011 77.1101737 2.075220e-04 0.795923951 0.92257590 19 1105253 1105274 22 + 1.896 1.888 -0.028
ENSG00000167468 E012 67.6095394 2.259102e-04 0.708112587 0.88166682 19 1105275 1105280 6 + 1.828 1.842 0.047
ENSG00000167468 E013 1.2243488 1.033214e-02 0.900460445 0.96768211 19 1105281 1105365 85 + 0.357 0.338 -0.115
ENSG00000167468 E014 167.7793642 1.054325e-04 0.940378492 0.98304758 19 1105366 1105453 88 + 2.225 2.227 0.007
ENSG00000167468 E015 158.1820579 1.281210e-04 0.949491478 0.98687390 19 1105454 1105510 57 + 2.201 2.200 -0.003
ENSG00000167468 E016 96.3645523 1.989884e-04 0.949324713 0.98676383 19 1105658 1105664 7 + 1.988 1.987 -0.005
ENSG00000167468 E017 318.5004213 9.520544e-05 0.568879828 0.80606110 19 1105665 1105809 145 + 2.498 2.508 0.031
ENSG00000167468 E018 1.3862286 1.005176e-02 0.005760046 0.05479799 19 1105810 1106180 371 + 0.099 0.525 3.206
ENSG00000167468 E019 2.3568993 6.278478e-03 0.152477058 0.41647410 19 1106181 1106241 61 + 0.403 0.608 1.000
ENSG00000167468 E020 125.2586916 1.599446e-03 0.297031443 0.59029787 19 1106242 1106266 25 + 2.082 2.115 0.111
ENSG00000167468 E021 3.3112825 1.275757e-01 0.873062794 0.95664070 19 1106378 1106399 22 + 0.635 0.633 -0.009
ENSG00000167468 E022 174.1588150 1.153638e-04 0.211079037 0.49589844 19 1106400 1106459 60 + 2.257 2.229 -0.091
ENSG00000167468 E023 125.2225228 5.663869e-04 0.141660508 0.40049499 19 1106540 1106572 33 + 2.121 2.081 -0.135
ENSG00000167468 E024 186.5149283 1.996752e-03 0.882926732 0.96056242 19 1106573 1106791 219 + 2.270 2.274 0.012

Help

Please Click HERE to learn more details about the results from DEXseq.