ENSG00000167552

1 Isoform Switch

Summary Plot

Only the isoforms with fraction > 5% are shown below.

  • Note:

    • About the Coding Potential: Please check the spreadsheet in the “Results” tag to confirm the coding potential. The above figure only show the predicted coding potential. The “gene_biotype” in the result spreadsheet is from the database record. Therefore, if you find conflicts between “gene_biotype” and “codingPotential”, please trust the “gene_biotype”.

    • Notes on IDR and IDR_w_binding: As the prediction of Intrinsically Disordered Regions (IDR) and Intrinsically Disordered Binding Regions (IDBR) are done by two different tools we require two things to annotate the Intrinsically Disordered Binding Regions (IDBR). Firstly the IDBR (predicted by ANCHOR2) must be a region of at least 15 amino acids (after the smoothing). Secondly the fraction of the IDBR which overlaps the IDR predictions (done by IUPred3, again after smoothing) must be at least 80%. When that is the case the IDR type will be annotated as “IDR_w_binding_region” instead of just “IDR”. The current default parameters have not been rigorously tested and should be considered experimental.

    • For the function of any other domain, please Click HERE to search it through Pfam database.

Results

isoform_id gene_id condition_1 condition_2 gene_name gene_biotype iso_biotype gene_overall_mean gene_value_1 gene_value_2 gene_stderr_1 gene_stderr_2 gene_log2_fold_change iso_overall_mean iso_value_1 iso_value_2 iso_stderr_1 iso_stderr_2 iso_log2_fold_change IF_overall IF1 IF2 dIF isoform_switch_q_value gene_switch_q_value PTC codingPotential
ENST00000301071 ENSG00000167552 No_inf pgKDN_inf TUBA1A protein_coding protein_coding 150.2287 76.97075 213.7331 0.8771216 3.259766 1.473308 138.639130 66.135113 202.044265 1.100671 3.466882 1.6110363 0.9094833 0.85915 0.945475 0.086325 0.0007964643 0.0007964643 FALSE  
ENST00000679733 ENSG00000167552 No_inf pgKDN_inf TUBA1A protein_coding protein_coding 150.2287 76.97075 213.7331 0.8771216 3.259766 1.473308 6.762644 5.313561 7.182879 1.101277 2.884652 0.4341777 0.0503000 0.06915 0.033475 -0.035675 0.5077157579 0.0007964643 FALSE  
  • Note:
    • The comparisons made can be identified as “from ‘condition_1’ to ‘condition_2’”, meaning ‘condition_1’ is considered the ground state and ‘condition_2’ the changed state. This also means that a positive dIF value indicates that the isoform usage is increased in ‘condition_2’ compared to ‘condition_1’. Since the ‘isoformFeatures’ entry is the most relevant part of the switchAnalyzeRlist object, the most-used standard methods have also been implemented to work directly on isoformFeatures.

Help

Please Click HERE to learn more details about the results of IsoformSwitchAnalyzeR.

2 Differential Exon Usage

Counts

All exons whithin this gene region are shown and numbering below.

Expression

All exons whithin this gene region are shown and numbering below.

Splicing

All exons whithin this gene region are shown and numbering below.

Transcripts

All isoforms whithin this gene region are shown below.

Results

groupID featureID exonBaseMean dispersion pvalue padj seqnames start end width strand pgKDN.inf No.inf log2fold_No.inf_pgKDN.inf
ENSG00000167552 E001 0.6158846 1.630214e-02 1.513987e-01 4.147468e-01 12 49184686 49184770 85 - 0.118 0.334 1.892
ENSG00000167552 E002 0.4886223 8.498733e-02 3.852851e-01   12 49184771 49184794 24 - 0.118 0.248 1.308
ENSG00000167552 E003 83.9337028 2.522338e-04 4.357316e-01 7.122678e-01 12 49184795 49184958 164 - 1.901 1.875 -0.088
ENSG00000167552 E004 306.6646902 7.545424e-05 1.957169e-01 4.760700e-01 12 49184959 49185620 662 - 2.445 2.466 0.070
ENSG00000167552 E005 227.4250420 1.033446e-04 1.709757e-01 4.433795e-01 12 49185621 49185990 370 - 2.330 2.305 -0.084
ENSG00000167552 E006 0.8630483 1.777860e-01 1.883682e-01 4.667149e-01 12 49186016 49186162 147 - 0.166 0.405 1.721
ENSG00000167552 E007 0.6089622 1.479676e-02 5.954339e-01 8.220718e-01 12 49186163 49186309 147 - 0.166 0.248 0.723
ENSG00000167552 E008 140.7824767 1.483333e-04 3.267447e-01 6.191640e-01 12 49186310 49186458 149 - 2.123 2.098 -0.081
ENSG00000167552 E009 2.8492766 5.956404e-03 3.701636e-04 6.881905e-03 12 49186459 49186587 129 - 0.351 0.831 2.215
ENSG00000167552 E010 0.4899798 9.431123e-02 3.945362e-01   12 49186588 49186610 23 - 0.118 0.248 1.308
ENSG00000167552 E011 92.5110340 1.701001e-04 4.805112e-01 7.458838e-01 12 49186611 49186833 223 - 1.941 1.919 -0.074
ENSG00000167552 E012 0.6161696 1.956634e-02 1.522106e-01 4.160201e-01 12 49186834 49186989 156 - 0.118 0.334 1.893
ENSG00000167552 E013 0.6261456 1.502306e-02 1.906987e-02 1.231312e-01 12 49186990 49187084 95 - 0.063 0.405 3.308
ENSG00000167552 E014 2.7590785 6.062542e-03 3.579861e-07 1.837664e-05 12 49187085 49187869 785 - 0.210 0.899 3.477
ENSG00000167552 E015 0.4882780 1.577952e-02 3.739928e-01   12 49188417 49188888 472 - 0.118 0.248 1.308
ENSG00000167552 E016 0.0000000       12 49188889 49188976 88 -      
ENSG00000167552 E017 0.0000000       12 49188977 49189080 104 -      

Help

Please Click HERE to learn more details about the results from DEXseq.