ENSG00000167895

1 Isoform Switch

Summary Plot

Only the isoforms with fraction > 5% are shown below.

  • Note:

    • About the Coding Potential: Please check the spreadsheet in the “Results” tag to confirm the coding potential. The above figure only show the predicted coding potential. The “gene_biotype” in the result spreadsheet is from the database record. Therefore, if you find conflicts between “gene_biotype” and “codingPotential”, please trust the “gene_biotype”.

    • Notes on IDR and IDR_w_binding: As the prediction of Intrinsically Disordered Regions (IDR) and Intrinsically Disordered Binding Regions (IDBR) are done by two different tools we require two things to annotate the Intrinsically Disordered Binding Regions (IDBR). Firstly the IDBR (predicted by ANCHOR2) must be a region of at least 15 amino acids (after the smoothing). Secondly the fraction of the IDBR which overlaps the IDR predictions (done by IUPred3, again after smoothing) must be at least 80%. When that is the case the IDR type will be annotated as “IDR_w_binding_region” instead of just “IDR”. The current default parameters have not been rigorously tested and should be considered experimental.

    • For the function of any other domain, please Click HERE to search it through Pfam database.

Results

isoform_id gene_id condition_1 condition_2 gene_name gene_biotype iso_biotype gene_overall_mean gene_value_1 gene_value_2 gene_stderr_1 gene_stderr_2 gene_log2_fold_change iso_overall_mean iso_value_1 iso_value_2 iso_stderr_1 iso_stderr_2 iso_log2_fold_change IF_overall IF1 IF2 dIF isoform_switch_q_value gene_switch_q_value PTC codingPotential
ENST00000318430 ENSG00000167895 No_inf pgKDN_inf TMC8 protein_coding protein_coding 28.2636 42.98604 18.15282 8.584914 1.159895 -1.243215 9.1245043 13.824676 6.5280775 0.6298142 2.7298798 -1.0813505 0.35314167 0.352000 0.353375 0.001375 0.959732162 0.005880837 FALSE TRUE
ENST00000590184 ENSG00000167895 No_inf pgKDN_inf TMC8 protein_coding retained_intron 28.2636 42.98604 18.15282 8.584914 1.159895 -1.243215 1.6886766 5.066030 0.0000000 1.6888253 0.0000000 -8.9875567 0.04423333 0.132700 0.000000 -0.132700 0.069901781 0.005880837 TRUE TRUE
ENST00000591003 ENSG00000167895 No_inf pgKDN_inf TMC8 protein_coding retained_intron 28.2636 42.98604 18.15282 8.584914 1.159895 -1.243215 3.1201232 7.796586 0.0000000 7.7965861 0.0000000 -9.6085480 0.05365000 0.115275 0.000000 -0.115275 1.000000000 0.005880837 FALSE FALSE
ENST00000592399 ENSG00000167895 No_inf pgKDN_inf TMC8 protein_coding protein_coding_CDS_not_defined 28.2636 42.98604 18.15282 8.584914 1.159895 -1.243215 1.8356670 2.298043 1.2512256 0.3899625 0.4769917 -0.8718438 0.06769167 0.057275 0.068475 0.011200 1.000000000 0.005880837   FALSE
ENST00000698566 ENSG00000167895 No_inf pgKDN_inf TMC8 protein_coding retained_intron 28.2636 42.98604 18.15282 8.584914 1.159895 -1.243215 1.3006353 1.160449 1.3209087 1.1604493 0.2479390 0.1853493 0.05622500 0.027950 0.071150 0.043200 0.204448517 0.005880837 FALSE TRUE
ENST00000698567 ENSG00000167895 No_inf pgKDN_inf TMC8 protein_coding protein_coding_CDS_not_defined 28.2636 42.98604 18.15282 8.584914 1.159895 -1.243215 1.6362476 0.000000 2.6118230 0.0000000 0.8781032 8.0344265 0.07537500 0.000000 0.143950 0.143950 0.005880837 0.005880837 FALSE TRUE
ENST00000698571 ENSG00000167895 No_inf pgKDN_inf TMC8 protein_coding protein_coding_CDS_not_defined 28.2636 42.98604 18.15282 8.584914 1.159895 -1.243215 1.0987423 0.000000 1.3936503 0.0000000 1.3936503 7.1330398 0.04456667 0.000000 0.065000 0.065000 0.764137642 0.005880837 FALSE FALSE
MSTRG.13379.1 ENSG00000167895 No_inf pgKDN_inf TMC8 protein_coding   28.2636 42.98604 18.15282 8.584914 1.159895 -1.243215 1.1361200 0.000000 1.9585068 0.0000000 1.9585068 7.6209578 0.05488333 0.000000 0.122300 0.122300 0.801088512 0.005880837 FALSE TRUE
MSTRG.13379.14 ENSG00000167895 No_inf pgKDN_inf TMC8 protein_coding   28.2636 42.98604 18.15282 8.584914 1.159895 -1.243215 0.8542409 2.562723 0.0000000 2.5627227 0.0000000 -8.0071521 0.02057500 0.061725 0.000000 -0.061725 0.994869462 0.005880837 FALSE TRUE
MSTRG.13379.17 ENSG00000167895 No_inf pgKDN_inf TMC8 protein_coding   28.2636 42.98604 18.15282 8.584914 1.159895 -1.243215 1.7061120 3.899063 0.6215394 1.4378289 0.2258262 -2.6298780 0.05743333 0.109850 0.036675 -0.073175 0.839167787 0.005880837 FALSE TRUE
  • Note:
    • The comparisons made can be identified as “from ‘condition_1’ to ‘condition_2’”, meaning ‘condition_1’ is considered the ground state and ‘condition_2’ the changed state. This also means that a positive dIF value indicates that the isoform usage is increased in ‘condition_2’ compared to ‘condition_1’. Since the ‘isoformFeatures’ entry is the most relevant part of the switchAnalyzeRlist object, the most-used standard methods have also been implemented to work directly on isoformFeatures.

Help

Please Click HERE to learn more details about the results of IsoformSwitchAnalyzeR.

2 Differential Exon Usage

Counts

All exons whithin this gene region are shown and numbering below.

Expression

All exons whithin this gene region are shown and numbering below.

Splicing

All exons whithin this gene region are shown and numbering below.

Transcripts

All isoforms whithin this gene region are shown below.

Results

groupID featureID exonBaseMean dispersion pvalue padj seqnames start end width strand pgKDN.inf No.inf log2fold_No.inf_pgKDN.inf
ENSG00000167895 E001 0.1186381 0.0119535801 2.557863e-01   17 78130770 78130770 1 + 0.129 0.000 -10.175
ENSG00000167895 E002 0.4991354 0.0153472668 7.567945e-01   17 78130771 78130777 7 + 0.129 0.182 0.595
ENSG00000167895 E003 0.4991354 0.0153472668 7.567945e-01   17 78130778 78130778 1 + 0.129 0.182 0.595
ENSG00000167895 E004 0.4991354 0.0153472668 7.567945e-01   17 78130779 78130787 9 + 0.129 0.182 0.595
ENSG00000167895 E005 0.4991354 0.0153472668 7.567945e-01   17 78130788 78130851 64 + 0.129 0.182 0.595
ENSG00000167895 E006 0.0000000       17 78130852 78130887 36 +      
ENSG00000167895 E007 0.0000000       17 78131281 78131385 105 +      
ENSG00000167895 E008 0.5071304 0.0158484736 1.847559e-01 0.462116845 17 78131386 78131405 20 + 0.000 0.229 12.402
ENSG00000167895 E009 19.7792744 0.0009653144 4.533923e-01 0.726147993 17 78131406 78131737 332 + 1.322 1.272 -0.176
ENSG00000167895 E010 9.9736209 0.0014801797 1.107626e-01 0.349308182 17 78131882 78132030 149 + 1.105 0.962 -0.523
ENSG00000167895 E011 0.3712740 0.0166592862 1.000000e+00   17 78132031 78132214 184 + 0.129 0.129 0.010
ENSG00000167895 E012 0.0000000       17 78132356 78132357 2 +      
ENSG00000167895 E013 0.0000000       17 78132358 78132358 1 +      
ENSG00000167895 E014 3.8324737 0.0080386964 5.483466e-01 0.793468030 17 78132359 78132465 107 + 0.711 0.633 -0.327
ENSG00000167895 E015 4.9305045 0.0042842299 2.408766e-01 0.530154530 17 78132466 78132488 23 + 0.837 0.698 -0.554
ENSG00000167895 E016 5.9168452 0.0023674887 2.381486e-01 0.527070502 17 78132489 78132508 20 + 0.898 0.768 -0.505
ENSG00000167895 E017 10.8705295 0.0015183309 4.243247e-01 0.703499096 17 78132788 78132870 83 + 1.093 1.023 -0.253
ENSG00000167895 E018 9.2301823 0.0146613185 1.306618e-01 0.383384899 17 78133406 78133435 30 + 1.081 0.928 -0.564
ENSG00000167895 E019 16.0547626 0.0013536840 1.681004e-01 0.439091907 17 78133436 78133542 107 + 1.269 1.168 -0.359
ENSG00000167895 E020 0.3813786 0.0251534322 3.243142e-01   17 78133543 78133553 11 + 0.000 0.182 11.985
ENSG00000167895 E021 8.4288588 0.0096310180 9.437789e-01 0.984427032 17 78133853 78133887 35 + 0.951 0.945 -0.022
ENSG00000167895 E022 15.9824907 0.0009945734 8.698347e-01 0.955211951 17 78133888 78134000 113 + 1.209 1.198 -0.040
ENSG00000167895 E023 0.3720293 0.0167353276 1.000000e+00   17 78134001 78134012 12 + 0.129 0.129 0.010
ENSG00000167895 E024 20.4726889 0.0006524646 6.065951e-02 0.247305931 17 78134394 78134515 122 + 1.382 1.260 -0.427
ENSG00000167895 E025 10.4108706 0.0014765215 9.831293e-01 0.998690264 17 78134516 78134537 22 + 1.028 1.030 0.010
ENSG00000167895 E026 9.7030980 0.0034720344 3.276392e-01 0.620210533 17 78134538 78134564 27 + 0.934 1.030 0.358
ENSG00000167895 E027 0.6328821 0.3640218583 2.460541e-01 0.536688389 17 78134565 78134571 7 + 0.000 0.271 12.126
ENSG00000167895 E028 0.6328821 0.3640218583 2.460541e-01 0.536688389 17 78134572 78134609 38 + 0.000 0.271 12.126
ENSG00000167895 E029 0.3714026 0.0166712350 1.000000e+00   17 78134868 78134869 2 + 0.129 0.129 0.010
ENSG00000167895 E030 18.9740695 0.0007426787 8.423312e-01 0.943457118 17 78134870 78135009 140 + 1.261 1.276 0.052
ENSG00000167895 E031 1.6034303 0.0101894223 7.074418e-01 0.881283487 17 78136620 78137049 430 + 0.435 0.378 -0.312
ENSG00000167895 E032 16.7072987 0.0009399705 7.353685e-01 0.895108556 17 78137235 78137323 89 + 1.236 1.212 -0.085
ENSG00000167895 E033 9.4893494 0.0016344653 2.138962e-01 0.499182115 17 78137324 78137358 35 + 1.068 0.954 -0.421
ENSG00000167895 E034 6.0465347 0.0166384631 4.713889e-04 0.008332970 17 78137359 78137653 295 + 0.435 0.928 2.114
ENSG00000167895 E035 2.5105021 0.0091494806 6.580417e-02 0.258424127 17 78137654 78137716 63 + 0.309 0.597 1.512
ENSG00000167895 E036 19.4361342 0.0010163590 5.369600e-02 0.230699910 17 78137717 78137814 98 + 1.180 1.322 0.498
ENSG00000167895 E037 10.9609150 0.0015207339 2.157447e-01 0.501637085 17 78138005 78138027 23 + 0.968 1.083 0.425
ENSG00000167895 E038 35.5357772 0.0004108182 5.206493e-01 0.774851517 17 78138028 78138188 161 + 1.554 1.522 -0.109
ENSG00000167895 E039 15.5410448 0.0161613556 1.569624e-01 0.423322759 17 78138349 78138362 14 + 1.269 1.147 -0.434
ENSG00000167895 E040 17.3164471 0.0064323546 4.040795e-03 0.042732601 17 78138363 78138420 58 + 1.370 1.152 -0.765
ENSG00000167895 E041 18.8611845 0.0022183272 7.227094e-02 0.272708548 17 78138421 78138479 59 + 1.350 1.225 -0.437
ENSG00000167895 E042 0.4982566 0.0152820618 7.566836e-01   17 78138550 78138573 24 + 0.129 0.182 0.595
ENSG00000167895 E043 26.8700879 0.0037812452 7.287120e-01 0.891847000 17 78138574 78138732 159 + 1.429 1.409 -0.069
ENSG00000167895 E044 10.1722082 0.0014967073 1.497052e-04 0.003295592 17 78138733 78139161 429 + 0.711 1.113 1.533
ENSG00000167895 E045 18.9632636 0.0007811435 8.831344e-01 0.960605822 17 78139162 78139240 79 + 1.277 1.268 -0.032
ENSG00000167895 E046 13.0683096 0.0038207424 5.021021e-05 0.001334385 17 78139241 78139704 464 + 0.814 1.212 1.469
ENSG00000167895 E047 8.8748640 0.0159811534 1.893430e-01 0.467990768 17 78140834 78140836 3 + 1.055 0.919 -0.505
ENSG00000167895 E048 207.5393688 0.0001386574 3.305985e-02 0.172709216 17 78140837 78142968 2132 + 2.260 2.301 0.137

Help

Please Click HERE to learn more details about the results from DEXseq.