ENSG00000167986

1 Isoform Switch

Summary Plot

Only the isoforms with fraction > 5% are shown below.

  • Note:

    • About the Coding Potential: Please check the spreadsheet in the “Results” tag to confirm the coding potential. The above figure only show the predicted coding potential. The “gene_biotype” in the result spreadsheet is from the database record. Therefore, if you find conflicts between “gene_biotype” and “codingPotential”, please trust the “gene_biotype”.

    • Notes on IDR and IDR_w_binding: As the prediction of Intrinsically Disordered Regions (IDR) and Intrinsically Disordered Binding Regions (IDBR) are done by two different tools we require two things to annotate the Intrinsically Disordered Binding Regions (IDBR). Firstly the IDBR (predicted by ANCHOR2) must be a region of at least 15 amino acids (after the smoothing). Secondly the fraction of the IDBR which overlaps the IDR predictions (done by IUPred3, again after smoothing) must be at least 80%. When that is the case the IDR type will be annotated as “IDR_w_binding_region” instead of just “IDR”. The current default parameters have not been rigorously tested and should be considered experimental.

    • For the function of any other domain, please Click HERE to search it through Pfam database.

Results

isoform_id gene_id condition_1 condition_2 gene_name gene_biotype iso_biotype gene_overall_mean gene_value_1 gene_value_2 gene_stderr_1 gene_stderr_2 gene_log2_fold_change iso_overall_mean iso_value_1 iso_value_2 iso_stderr_1 iso_stderr_2 iso_log2_fold_change IF_overall IF1 IF2 dIF isoform_switch_q_value gene_switch_q_value PTC codingPotential
ENST00000301764 ENSG00000167986 No_inf pgKDN_inf DDB1 protein_coding protein_coding 85.50816 56.84681 97.99181 1.398911 2.732963 0.7854751 54.923000 26.130609 67.3392314 3.737517 4.1935775 1.3653687 0.61655833 0.456400 0.687950 0.231550 0.04505338 0.01393678 FALSE TRUE
ENST00000451943 ENSG00000167986 No_inf pgKDN_inf DDB1 protein_coding retained_intron 85.50816 56.84681 97.99181 1.398911 2.732963 0.7854751 6.808845 10.464787 6.6786519 1.483427 2.2730706 -0.6471336 0.09367500 0.183100 0.066425 -0.116675 0.43264813 0.01393678 FALSE TRUE
ENST00000680452 ENSG00000167986 No_inf pgKDN_inf DDB1 protein_coding retained_intron 85.50816 56.84681 97.99181 1.398911 2.732963 0.7854751 2.779685 5.710993 0.4596079 1.623058 0.4596079 -3.6067372 0.04198333 0.099550 0.004450 -0.095100 0.01393678 0.01393678 FALSE TRUE
ENST00000680717 ENSG00000167986 No_inf pgKDN_inf DDB1 protein_coding protein_coding 85.50816 56.84681 97.99181 1.398911 2.732963 0.7854751 12.336146 3.228035 16.9539153 2.063844 5.2844357 2.3892786 0.13202500 0.058675 0.175150 0.116475 0.40928691 0.01393678 FALSE TRUE
  • Note:
    • The comparisons made can be identified as “from ‘condition_1’ to ‘condition_2’”, meaning ‘condition_1’ is considered the ground state and ‘condition_2’ the changed state. This also means that a positive dIF value indicates that the isoform usage is increased in ‘condition_2’ compared to ‘condition_1’. Since the ‘isoformFeatures’ entry is the most relevant part of the switchAnalyzeRlist object, the most-used standard methods have also been implemented to work directly on isoformFeatures.

Help

Please Click HERE to learn more details about the results of IsoformSwitchAnalyzeR.

2 Differential Exon Usage

Counts

All exons whithin this gene region are shown and numbering below.

Expression

All exons whithin this gene region are shown and numbering below.

Splicing

All exons whithin this gene region are shown and numbering below.

Transcripts

All isoforms whithin this gene region are shown below.

Results

groupID featureID exonBaseMean dispersion pvalue padj seqnames start end width strand pgKDN.inf No.inf log2fold_No.inf_pgKDN.inf
ENSG00000167986 E001 1.4403806 9.011428e-03 4.385426e-01 0.7147152185 11 61299451 61299454 4 - 0.421 0.299 -0.725
ENSG00000167986 E002 2.7624700 1.006160e-02 3.442385e-01 0.6355586677 11 61299455 61299462 8 - 0.612 0.474 -0.642
ENSG00000167986 E003 2.8897323 5.836114e-03 5.148221e-01 0.7711822580 11 61299463 61299463 1 - 0.612 0.520 -0.420
ENSG00000167986 E004 4.0939404 4.591877e-03 4.575361e-01 0.7293909069 11 61299464 61299469 6 - 0.729 0.633 -0.403
ENSG00000167986 E005 22.2704553 5.955439e-04 6.037239e-01 0.8271413142 11 61299470 61299555 86 - 1.365 1.331 -0.116
ENSG00000167986 E006 53.9404071 2.628586e-04 1.102398e-01 0.3483973469 11 61299556 61299680 125 - 1.699 1.766 0.226
ENSG00000167986 E007 172.0642100 9.704127e-05 4.438713e-06 0.0001699060 11 61299681 61300050 370 - 2.181 2.287 0.353
ENSG00000167986 E008 41.6160777 3.562338e-04 4.932707e-01 0.7552132360 11 61300051 61300070 20 - 1.603 1.636 0.112
ENSG00000167986 E009 112.9164706 1.378182e-04 7.511678e-03 0.0662436803 11 61300071 61300219 149 - 2.012 2.089 0.258
ENSG00000167986 E010 1.3463555 9.042479e-02 5.198715e-01 0.7745083675 11 61300220 61300808 589 - 0.320 0.423 0.596
ENSG00000167986 E011 105.9189411 2.352254e-04 5.626767e-02 0.2365307340 11 61300809 61300932 124 - 1.992 2.050 0.193
ENSG00000167986 E012 0.4900408 1.580189e-02 5.560107e-01   11 61300933 61300936 4 - 0.135 0.220 0.860
ENSG00000167986 E013 2.0772643 8.105058e-03 3.367249e-01 0.6287555157 11 61300937 61301711 775 - 0.421 0.561 0.690
ENSG00000167986 E014 2.5792302 1.871042e-02 1.331780e-01 0.3875901832 11 61301712 61302256 545 - 0.450 0.665 0.998
ENSG00000167986 E015 86.8053072 1.837077e-04 1.393576e-01 0.3969010350 11 61302257 61302359 103 - 1.910 1.959 0.165
ENSG00000167986 E016 2.7136666 6.018234e-03 2.704379e-02 0.1528108543 11 61302360 61302580 221 - 0.421 0.723 1.391
ENSG00000167986 E017 1.6055925 1.899884e-01 1.399367e-01 0.3978778464 11 61302581 61302581 1 - 0.281 0.561 1.538
ENSG00000167986 E018 127.0908864 3.146934e-04 4.965039e-01 0.7574956791 11 61302582 61302751 170 - 2.086 2.105 0.064
ENSG00000167986 E019 1.9409656 1.374919e-01 9.161173e-01 0.9737053414 11 61302752 61303045 294 - 0.450 0.474 0.124
ENSG00000167986 E020 82.4137689 1.917274e-04 2.714846e-01 0.5652348963 11 61303046 61303155 110 - 1.892 1.930 0.127
ENSG00000167986 E021 2.6981460 1.518476e-02 1.819536e-01 0.4579765756 11 61303156 61303581 426 - 0.477 0.665 0.860
ENSG00000167986 E022 0.2442663 1.630648e-02 6.426181e-01   11 61303751 61303864 114 - 0.072 0.124 0.860
ENSG00000167986 E023 108.0370009 2.506579e-04 6.247594e-01 0.8385803099 11 61303865 61304035 171 - 2.028 2.014 -0.049
ENSG00000167986 E024 74.3819510 3.483959e-03 2.130985e-01 0.4983588275 11 61308983 61309077 95 - 1.882 1.828 -0.182
ENSG00000167986 E025 30.0967255 6.023442e-03 6.560412e-01 0.8559418865 11 61309796 61309808 13 - 1.467 1.496 0.098
ENSG00000167986 E026 40.0228809 1.183389e-03 6.760331e-01 0.8658253105 11 61309809 61309861 53 - 1.591 1.612 0.072
ENSG00000167986 E027 67.8033103 2.777382e-04 4.607571e-01 0.7319790207 11 61309862 61309960 99 - 1.813 1.841 0.094
ENSG00000167986 E028 0.1265070 1.229608e-02 2.856960e-01   11 61309961 61309979 19 - 0.000 0.124 13.700
ENSG00000167986 E029 32.4156589 3.548216e-03 4.008417e-01 0.6841189461 11 61310295 61310295 1 - 1.491 1.540 0.166
ENSG00000167986 E030 82.8531651 1.774229e-04 3.647876e-01 0.6533270790 11 61310296 61310418 123 - 1.897 1.928 0.104
ENSG00000167986 E031 1.2398956 9.996872e-03 2.859221e-02 0.1583744551 11 61310419 61311349 931 - 0.189 0.520 2.083
ENSG00000167986 E032 68.1107779 2.145292e-04 1.689331e-01 0.4404105331 11 61311784 61311895 112 - 1.805 1.857 0.174
ENSG00000167986 E033 48.0623230 2.971254e-04 6.705037e-01 0.8630640748 11 61311989 61312084 96 - 1.683 1.664 -0.064
ENSG00000167986 E034 36.8814408 3.794478e-04 3.157927e-01 0.6086103700 11 61313499 61313537 39 - 1.583 1.531 -0.175
ENSG00000167986 E035 38.1559648 6.341356e-04 9.141898e-01 0.9729445660 11 61313538 61313585 48 - 1.580 1.575 -0.018
ENSG00000167986 E036 54.3322494 3.361128e-04 4.577498e-01 0.7296020969 11 61313586 61313672 87 - 1.740 1.709 -0.106
ENSG00000167986 E037 33.9568476 3.086789e-03 9.440793e-03 0.0774652411 11 61313673 61313706 34 - 1.580 1.427 -0.527
ENSG00000167986 E038 0.7263444 1.410799e-02 9.113257e-01 0.9717869788 11 61313707 61313859 153 - 0.237 0.220 -0.140
ENSG00000167986 E039 0.3711203 1.655185e-02 2.806585e-01   11 61313860 61313861 2 - 0.072 0.220 1.860
ENSG00000167986 E040 56.4556328 1.848422e-03 2.178602e-02 0.1339575277 11 61313862 61313969 108 - 1.781 1.677 -0.353
ENSG00000167986 E041 23.5590125 6.373537e-04 2.757487e-01 0.5692686486 11 61314047 61314047 1 - 1.401 1.331 -0.241
ENSG00000167986 E042 68.6211489 2.259576e-04 3.563421e-01 0.6461310421 11 61314048 61314202 155 - 1.841 1.806 -0.117
ENSG00000167986 E043 23.1119811 6.045783e-04 1.574949e-01 0.4241355720 11 61314203 61314210 8 - 1.333 1.421 0.307
ENSG00000167986 E044 0.7353160 1.429355e-02 4.732410e-01 0.7403013084 11 61314211 61314261 51 - 0.189 0.299 0.860
ENSG00000167986 E045 1.1059629 1.089095e-02 2.266801e-01 0.5148990130 11 61314262 61314307 46 - 0.237 0.423 1.182
ENSG00000167986 E046 30.8435264 5.255341e-04 3.824363e-01 0.6686654001 11 61314308 61314337 30 - 1.470 1.518 0.165
ENSG00000167986 E047 58.4330176 5.379018e-04 3.009297e-02 0.1632152330 11 61314338 61314452 115 - 1.791 1.700 -0.309
ENSG00000167986 E048 31.2987479 1.128883e-03 3.838122e-03 0.0412936913 11 61314453 61314486 34 - 1.550 1.382 -0.580
ENSG00000167986 E049 2.1226110 2.535558e-02 1.064010e-03 0.0157136656 11 61314487 61314883 397 - 0.237 0.723 2.561
ENSG00000167986 E050 0.7523083 1.405115e-02 1.729872e-02 0.1151411820 11 61314884 61314928 45 - 0.072 0.423 3.182
ENSG00000167986 E051 2.9906934 1.228465e-01 2.981470e-03 0.0343889208 11 61314929 61315331 403 - 0.320 0.841 2.445
ENSG00000167986 E052 2.8213172 5.260707e-03 1.081780e-01 0.3449479626 11 61315332 61315523 192 - 0.477 0.695 0.986
ENSG00000167986 E053 4.8690766 5.535589e-02 2.495669e-05 0.0007453014 11 61315524 61316280 757 - 0.421 1.037 2.597
ENSG00000167986 E054 0.4992916 2.812016e-02 1.154690e-01   11 61316281 61316284 4 - 0.072 0.299 2.445
ENSG00000167986 E055 50.5082633 2.837013e-04 3.929436e-03 0.0419331608 11 61316285 61316393 109 - 1.741 1.612 -0.440
ENSG00000167986 E056 36.4208044 4.084036e-04 5.530300e-01 0.7963078504 11 61316492 61316567 76 - 1.570 1.540 -0.104
ENSG00000167986 E057 0.1268540 1.229118e-02 2.857444e-01   11 61316568 61316569 2 - 0.000 0.124 13.700
ENSG00000167986 E058 1.4870560 5.845724e-02 4.413256e-02 0.2053883220 11 61321255 61321594 340 - 0.237 0.561 1.860
ENSG00000167986 E059 41.1769559 1.995587e-03 1.041797e-01 0.3372645088 11 61321595 61321697 103 - 1.640 1.556 -0.288
ENSG00000167986 E060 0.1271363 1.228680e-02 2.858224e-01   11 61321698 61322164 467 - 0.000 0.124 13.700
ENSG00000167986 E061 20.5588733 8.627148e-03 6.360882e-01 0.8448073130 11 61322296 61322316 21 - 1.333 1.297 -0.127
ENSG00000167986 E062 35.9342716 4.172706e-04 4.292022e-01 0.7075845272 11 61322317 61322412 96 - 1.568 1.527 -0.140
ENSG00000167986 E063 0.8778423 2.722221e-02 7.303522e-03 0.0649584722 11 61322413 61322958 546 - 0.072 0.474 3.445
ENSG00000167986 E064 31.5822239 4.359926e-04 1.258533e-02 0.0932386199 11 61323011 61323094 84 - 1.546 1.405 -0.485
ENSG00000167986 E065 0.3798680 3.510943e-02 3.142765e-02   11 61323095 61323660 566 - 0.000 0.299 15.021
ENSG00000167986 E066 0.1268540 1.229118e-02 2.857444e-01   11 61323661 61323757 97 - 0.000 0.124 13.700
ENSG00000167986 E067 0.0000000       11 61323758 61323978 221 -      
ENSG00000167986 E068 49.4576891 3.194677e-04 7.359343e-03 0.0653148660 11 61323979 61324137 159 - 1.730 1.608 -0.413
ENSG00000167986 E069 0.1176306 1.173022e-02 1.000000e+00   11 61324138 61324237 100 - 0.072 0.000 -13.392
ENSG00000167986 E070 0.1176306 1.173022e-02 1.000000e+00   11 61324238 61324387 150 - 0.072 0.000 -13.392
ENSG00000167986 E071 33.8715962 2.912786e-03 1.411357e-02 0.1007146335 11 61325611 61325708 98 - 1.576 1.432 -0.494
ENSG00000167986 E072 0.1271363 1.228680e-02 2.858224e-01   11 61325709 61326229 521 - 0.000 0.124 13.700
ENSG00000167986 E073 38.9088385 3.725038e-04 3.499537e-03 0.0387644387 11 61326779 61326893 115 - 1.637 1.487 -0.512
ENSG00000167986 E074 0.1176306 1.173022e-02 1.000000e+00   11 61326894 61326924 31 - 0.072 0.000 -13.392
ENSG00000167986 E075 0.0000000       11 61327511 61327551 41 -      
ENSG00000167986 E076 0.0000000       11 61328746 61328862 117 -      
ENSG00000167986 E077 0.0000000       11 61329362 61329362 1 -      
ENSG00000167986 E078 37.1243308 1.323521e-02 6.445110e-02 0.2558029086 11 61329363 61329473 111 - 1.610 1.482 -0.438
ENSG00000167986 E079 38.1399871 3.629916e-04 7.310005e-01 0.8931580579 11 61329474 61329584 111 - 1.585 1.568 -0.058
ENSG00000167986 E080 37.3664063 7.882263e-04 4.262752e-01 0.7049477545 11 61329958 61330074 117 - 1.585 1.544 -0.140
ENSG00000167986 E081 0.2542726 2.316782e-01 1.310491e-01   11 61330075 61330183 109 - 0.000 0.220 13.719
ENSG00000167986 E082 0.0000000       11 61330184 61330209 26 -      
ENSG00000167986 E083 37.9678845 2.030542e-03 4.673829e-01 0.7357802437 11 61331543 61331691 149 - 1.591 1.552 -0.133
ENSG00000167986 E084 3.4546437 4.086803e-03 7.565577e-03 0.0665538755 11 61331692 61332633 942 - 0.477 0.820 1.488
ENSG00000167986 E085 0.3532727 1.574212e-02 2.800011e-01   11 61332634 61332737 104 - 0.189 0.000 -14.885
ENSG00000167986 E086 0.2441377 1.620530e-02 6.427532e-01   11 61332738 61332907 170 - 0.072 0.124 0.860
ENSG00000167986 E087 27.7653577 4.932784e-04 1.045286e-01 0.3379244724 11 61332908 61333008 101 - 1.478 1.382 -0.332
ENSG00000167986 E088 18.3960459 9.401843e-04 4.989493e-01 0.7592565316 11 61333009 61333140 132 - 1.291 1.243 -0.168
ENSG00000167986 E089 0.3621491 1.659192e-02 1.000000e+00   11 61333145 61333224 80 - 0.135 0.124 -0.140
ENSG00000167986 E090 0.2533610 1.598778e-02 9.650169e-02   11 61333526 61333603 78 - 0.000 0.220 14.633
ENSG00000167986 E091 0.0000000       11 61333604 61333807 204 -      
ENSG00000167986 E092 0.0000000       11 61335311 61335435 125 -      
ENSG00000167986 E093 0.0000000       11 61342368 61342596 229 -      

Help

Please Click HERE to learn more details about the results from DEXseq.