ENSG00000168003

1 Isoform Switch

Summary Plot

Only the isoforms with fraction > 5% are shown below.

  • Note:

    • About the Coding Potential: Please check the spreadsheet in the “Results” tag to confirm the coding potential. The above figure only show the predicted coding potential. The “gene_biotype” in the result spreadsheet is from the database record. Therefore, if you find conflicts between “gene_biotype” and “codingPotential”, please trust the “gene_biotype”.

    • Notes on IDR and IDR_w_binding: As the prediction of Intrinsically Disordered Regions (IDR) and Intrinsically Disordered Binding Regions (IDBR) are done by two different tools we require two things to annotate the Intrinsically Disordered Binding Regions (IDBR). Firstly the IDBR (predicted by ANCHOR2) must be a region of at least 15 amino acids (after the smoothing). Secondly the fraction of the IDBR which overlaps the IDR predictions (done by IUPred3, again after smoothing) must be at least 80%. When that is the case the IDR type will be annotated as “IDR_w_binding_region” instead of just “IDR”. The current default parameters have not been rigorously tested and should be considered experimental.

    • For the function of any other domain, please Click HERE to search it through Pfam database.

Results

isoform_id gene_id condition_1 condition_2 gene_name gene_biotype iso_biotype gene_overall_mean gene_value_1 gene_value_2 gene_stderr_1 gene_stderr_2 gene_log2_fold_change iso_overall_mean iso_value_1 iso_value_2 iso_stderr_1 iso_stderr_2 iso_log2_fold_change IF_overall IF1 IF2 dIF isoform_switch_q_value gene_switch_q_value PTC codingPotential
ENST00000338663 ENSG00000168003 No_inf pgKDN_inf SLC3A2 protein_coding protein_coding 183.061 79.05119 181.4342 1.062849 4.121797 1.198484 129.48754 39.118333 123.529332 2.390716 4.071212 1.658685 0.6534917 0.495000 0.683150 0.188150 0.01936416 0.01936416 FALSE TRUE
ENST00000536981 ENSG00000168003 No_inf pgKDN_inf SLC3A2 protein_coding protein_coding 183.061 79.05119 181.4342 1.062849 4.121797 1.198484 22.37906 5.647903 33.790715 5.647903 9.559372 2.578714 0.1164500 0.071025 0.183000 0.111975 0.11505312 0.01936416 FALSE TRUE
ENST00000679594 ENSG00000168003 No_inf pgKDN_inf SLC3A2 protein_coding retained_intron 183.061 79.05119 181.4342 1.062849 4.121797 1.198484 11.91928 20.183454 6.937397 4.779322 2.393466 -1.539343 0.1081833 0.255775 0.038625 -0.217150 0.07610564 0.01936416 FALSE TRUE
  • Note:
    • The comparisons made can be identified as “from ‘condition_1’ to ‘condition_2’”, meaning ‘condition_1’ is considered the ground state and ‘condition_2’ the changed state. This also means that a positive dIF value indicates that the isoform usage is increased in ‘condition_2’ compared to ‘condition_1’. Since the ‘isoformFeatures’ entry is the most relevant part of the switchAnalyzeRlist object, the most-used standard methods have also been implemented to work directly on isoformFeatures.

Help

Please Click HERE to learn more details about the results of IsoformSwitchAnalyzeR.

2 Differential Exon Usage

Counts

All exons whithin this gene region are shown and numbering below.

Expression

All exons whithin this gene region are shown and numbering below.

Splicing

All exons whithin this gene region are shown and numbering below.

Transcripts

All isoforms whithin this gene region are shown below.

Results

groupID featureID exonBaseMean dispersion pvalue padj seqnames start end width strand pgKDN.inf No.inf log2fold_No.inf_pgKDN.inf
ENSG00000168003 E001 0.2539903 1.603056e-02 8.484000e-02   11 62856004 62856101 98 + 0.000 0.227 12.336
ENSG00000168003 E002 0.2539903 1.603056e-02 8.484000e-02   11 62856102 62856108 7 + 0.000 0.227 14.235
ENSG00000168003 E003 0.2539903 1.603056e-02 8.484000e-02   11 62856109 62856110 2 + 0.000 0.227 14.235
ENSG00000168003 E004 0.0000000       11 62856111 62856143 33 +      
ENSG00000168003 E005 0.1187032 1.186333e-02 1.000000e+00   11 62856144 62856160 17 + 0.070 0.000 -12.790
ENSG00000168003 E006 0.2373413 1.574484e-02 5.770796e-01   11 62856161 62856167 7 + 0.130 0.000 -13.718
ENSG00000168003 E007 1.3257024 1.086042e-02 6.440349e-01 0.8492134309 11 62856168 62856381 214 + 0.379 0.308 -0.434
ENSG00000168003 E008 0.0000000       11 62856382 62856453 72 +      
ENSG00000168003 E009 0.4719109 1.587300e-02 1.787976e-01   11 62870745 62870795 51 + 0.230 0.000 -14.665
ENSG00000168003 E010 0.3542802 2.870753e-02 3.159067e-01   11 62870796 62870837 42 + 0.183 0.000 -14.163
ENSG00000168003 E011 1.3454351 2.307915e-01 6.114221e-01 0.8308704974 11 62871577 62871669 93 + 0.311 0.435 0.718
ENSG00000168003 E012 0.8532560 1.746855e-01 6.408560e-01 0.8475909025 11 62876784 62876786 3 + 0.230 0.308 0.567
ENSG00000168003 E013 1.0878907 1.362710e-01 9.917164e-01 1.0000000000 11 62876787 62876879 93 + 0.311 0.308 -0.018
ENSG00000168003 E014 0.0000000       11 62879891 62879998 108 +      
ENSG00000168003 E015 0.2536433 1.599328e-02 8.488640e-02   11 62880342 62880600 259 + 0.000 0.227 14.236
ENSG00000168003 E016 0.7326703 5.057544e-02 4.309772e-01 0.7087183512 11 62880863 62880890 28 + 0.183 0.308 0.982
ENSG00000168003 E017 0.8513735 1.549932e-02 6.242523e-01 0.8383800296 11 62880891 62880895 5 + 0.230 0.308 0.566
ENSG00000168003 E018 3.1364483 1.380934e-02 7.501905e-01 0.9014575061 11 62880896 62880906 11 + 0.617 0.574 -0.189
ENSG00000168003 E019 35.7804292 3.927812e-04 2.134928e-02 0.1323355748 11 62880907 62881018 112 + 1.585 1.465 -0.409
ENSG00000168003 E020 30.0295066 6.065082e-04 7.405660e-02 0.2772483763 11 62881019 62881056 38 + 1.505 1.405 -0.345
ENSG00000168003 E021 70.2925685 2.345217e-04 6.000917e-05 0.0015471007 11 62881057 62881182 126 + 1.881 1.729 -0.513
ENSG00000168003 E022 84.7002076 1.860581e-04 5.965317e-04 0.0100259714 11 62881183 62881315 133 + 1.951 1.835 -0.390
ENSG00000168003 E023 80.6363461 6.688427e-04 6.241716e-02 0.2510932520 11 62881316 62881447 132 + 1.914 1.850 -0.215
ENSG00000168003 E024 0.5954966 1.689424e-01 5.821719e-01 0.8138831344 11 62881448 62881453 6 + 0.229 0.128 -1.017
ENSG00000168003 E025 0.0000000       11 62881698 62881698 1 +      
ENSG00000168003 E026 1.0082801 1.022488e-01 4.257156e-03 0.0443510630 11 62881699 62881718 20 + 0.070 0.532 3.789
ENSG00000168003 E027 0.8895770 1.062366e-01 6.789366e-04 0.0110826797 11 62881719 62881721 3 + 0.000 0.532 15.456
ENSG00000168003 E028 1.5162607 8.010624e-02 1.539806e-04 0.0033692886 11 62881722 62881758 37 + 0.070 0.680 4.441
ENSG00000168003 E029 1.5162607 8.010624e-02 1.539806e-04 0.0033692886 11 62881759 62881785 27 + 0.070 0.680 4.441
ENSG00000168003 E030 1.9961363 6.974173e-03 8.905266e-04 0.0137297034 11 62881786 62881804 19 + 0.230 0.710 2.566
ENSG00000168003 E031 4.1155714 4.054114e-02 2.006377e-05 0.0006197706 11 62881805 62881880 76 + 0.379 0.982 2.625
ENSG00000168003 E032 3.8211054 4.195907e-03 6.583251e-03 0.0603640049 11 62881881 62881892 12 + 0.514 0.857 1.451
ENSG00000168003 E033 36.4067053 2.647915e-03 1.619905e-01 0.4303205289 11 62881893 62881900 8 + 1.524 1.604 0.275
ENSG00000168003 E034 120.5236868 2.039397e-04 4.824221e-01 0.7473274669 11 62881901 62882066 166 + 2.071 2.055 -0.054
ENSG00000168003 E035 6.2610170 2.583398e-03 5.760830e-03 0.0547979912 11 62882067 62882504 438 + 0.714 1.012 1.151
ENSG00000168003 E036 1.3689805 2.034898e-02 1.039852e-02 0.0823944176 11 62882505 62882529 25 + 0.183 0.574 2.396
ENSG00000168003 E037 3.8344496 3.651367e-03 5.838563e-04 0.0098528483 11 62882530 62882618 89 + 0.465 0.896 1.844
ENSG00000168003 E038 1.6161093 8.316051e-03 1.020910e-02 0.0813832570 11 62882619 62882666 48 + 0.230 0.612 2.151
ENSG00000168003 E039 2.9752398 5.924655e-03 1.265016e-03 0.0179274801 11 62882667 62882774 108 + 0.379 0.813 1.981
ENSG00000168003 E040 2.3496584 6.136295e-03 1.016056e-02 0.0811250062 11 62882775 62882807 33 + 0.346 0.710 1.759
ENSG00000168003 E041 2.4776801 5.760001e-03 5.064805e-03 0.0501036650 11 62882808 62882907 100 + 0.346 0.738 1.874
ENSG00000168003 E042 85.6756245 5.236175e-04 9.071667e-01 0.9704972065 11 62882908 62882999 92 + 1.916 1.924 0.027
ENSG00000168003 E043 6.0884209 3.730265e-02 8.706519e-06 0.0003031432 11 62883348 62883988 641 + 0.536 1.115 2.303
ENSG00000168003 E044 2.1018078 4.232628e-02 1.746007e-02 0.1158577336 11 62883989 62884112 124 + 0.311 0.680 1.856
ENSG00000168003 E045 2.9479872 4.796660e-03 4.393626e-02 0.2048105700 11 62884113 62884456 344 + 0.465 0.738 1.222
ENSG00000168003 E046 90.7429343 3.838977e-04 3.710409e-01 0.6590824296 11 62884457 62884525 69 + 1.931 1.964 0.112
ENSG00000168003 E047 94.1415808 1.791580e-04 8.877389e-01 0.9624175711 11 62884632 62884690 59 + 1.956 1.964 0.028
ENSG00000168003 E048 191.0097028 1.592511e-04 7.779620e-01 0.9148664358 11 62885177 62885357 181 + 2.265 2.262 -0.008
ENSG00000168003 E049 0.9970753 2.141053e-02 1.963574e-02 0.1255523669 11 62885358 62885464 107 + 0.130 0.486 2.566
ENSG00000168003 E050 167.3003404 1.014652e-04 7.289245e-01 0.8919146666 11 62885465 62885608 144 + 2.208 2.204 -0.014
ENSG00000168003 E051 2.3037101 8.787630e-03 7.856030e-01 0.9174636405 11 62885609 62886196 588 + 0.490 0.532 0.204
ENSG00000168003 E052 0.3631878 1.655006e-02 1.000000e+00   11 62886437 62886440 4 + 0.130 0.128 -0.019
ENSG00000168003 E053 0.5999299 4.784968e-02 5.254450e-01 0.7782126729 11 62886441 62886460 20 + 0.230 0.128 -1.019
ENSG00000168003 E054 1.9518833 4.500397e-02 4.426323e-01 0.7179180560 11 62886461 62886568 108 + 0.410 0.532 0.618
ENSG00000168003 E055 0.8540801 1.705981e-02 6.252240e-01 0.8386805763 11 62887870 62888100 231 + 0.230 0.308 0.566
ENSG00000168003 E056 0.0000000       11 62888101 62888112 12 +      
ENSG00000168003 E057 0.8521935 1.524448e-02 6.237943e-01 0.8380934668 11 62888113 62888134 22 + 0.230 0.308 0.566
ENSG00000168003 E058 94.1819592 1.699245e-04 7.686543e-01 0.9105427152 11 62888135 62888218 84 + 1.954 1.968 0.045
ENSG00000168003 E059 2.4821133 5.995905e-03 1.141955e-03 0.0165921852 11 62888219 62888330 112 + 0.311 0.765 2.204
ENSG00000168003 E060 260.8308195 9.661238e-05 3.124918e-01 0.6058643179 11 62888331 62888651 321 + 2.404 2.389 -0.049
ENSG00000168003 E061 87.3237298 1.437028e-03 5.496782e-01 0.7944035123 11 62888652 62888880 229 + 1.918 1.943 0.085

Help

Please Click HERE to learn more details about the results from DEXseq.