ENSG00000168067

1 Isoform Switch

Summary Plot

Only the isoforms with fraction > 5% are shown below.

  • Note:

    • About the Coding Potential: Please check the spreadsheet in the “Results” tag to confirm the coding potential. The above figure only show the predicted coding potential. The “gene_biotype” in the result spreadsheet is from the database record. Therefore, if you find conflicts between “gene_biotype” and “codingPotential”, please trust the “gene_biotype”.

    • Notes on IDR and IDR_w_binding: As the prediction of Intrinsically Disordered Regions (IDR) and Intrinsically Disordered Binding Regions (IDBR) are done by two different tools we require two things to annotate the Intrinsically Disordered Binding Regions (IDBR). Firstly the IDBR (predicted by ANCHOR2) must be a region of at least 15 amino acids (after the smoothing). Secondly the fraction of the IDBR which overlaps the IDR predictions (done by IUPred3, again after smoothing) must be at least 80%. When that is the case the IDR type will be annotated as “IDR_w_binding_region” instead of just “IDR”. The current default parameters have not been rigorously tested and should be considered experimental.

    • For the function of any other domain, please Click HERE to search it through Pfam database.

Results

isoform_id gene_id condition_1 condition_2 gene_name gene_biotype iso_biotype gene_overall_mean gene_value_1 gene_value_2 gene_stderr_1 gene_stderr_2 gene_log2_fold_change iso_overall_mean iso_value_1 iso_value_2 iso_stderr_1 iso_stderr_2 iso_log2_fold_change IF_overall IF1 IF2 dIF isoform_switch_q_value gene_switch_q_value PTC codingPotential
ENST00000294066 ENSG00000168067 No_inf pgKDN_inf MAP4K2 protein_coding protein_coding 12.58973 7.512908 14.80632 0.3833315 3.796001 0.9778248 0.4371343 0.7615735 0.2415469 0.1301718 0.0414844 -1.61697587 0.05315833 0.103425 0.018425 -0.085000 0.219872400 0.004542376 FALSE TRUE
ENST00000377350 ENSG00000168067 No_inf pgKDN_inf MAP4K2 protein_coding protein_coding 12.58973 7.512908 14.80632 0.3833315 3.796001 0.9778248 2.9363738 2.9738937 2.8696026 0.6178639 0.3663511 -0.05132643 0.36417500 0.390900 0.302975 -0.087925 0.824020795 0.004542376 FALSE TRUE
ENST00000424945 ENSG00000168067 No_inf pgKDN_inf MAP4K2 protein_coding nonsense_mediated_decay 12.58973 7.512908 14.80632 0.3833315 3.796001 0.9778248 0.1362856 0.4088568 0.0000000 0.4088568 0.0000000 -5.38838535 0.02024167 0.060725 0.000000 -0.060725 0.824039411 0.004542376 TRUE TRUE
ENST00000489952 ENSG00000168067 No_inf pgKDN_inf MAP4K2 protein_coding retained_intron 12.58973 7.512908 14.80632 0.3833315 3.796001 0.9778248 0.6308659 0.6759771 0.4588480 0.3935410 0.2650181 -0.54904002 0.08398333 0.089200 0.026150 -0.063050 0.844532020 0.004542376 TRUE TRUE
MSTRG.4919.12 ENSG00000168067 No_inf pgKDN_inf MAP4K2 protein_coding   12.58973 7.512908 14.80632 0.3833315 3.796001 0.9778248 6.4810670 0.0000000 9.7604777 0.0000000 4.0556599 9.93228528 0.24693333 0.000000 0.522925 0.522925 0.004542376 0.004542376   FALSE
MSTRG.4919.3 ENSG00000168067 No_inf pgKDN_inf MAP4K2 protein_coding   12.58973 7.512908 14.80632 0.3833315 3.796001 0.9778248 1.0179280 1.2047431 0.6351774 0.5775712 0.6351774 -0.91288339 0.10765000 0.161650 0.038025 -0.123625 0.476333458 0.004542376 FALSE TRUE
MSTRG.4919.4 ENSG00000168067 No_inf pgKDN_inf MAP4K2 protein_coding   12.58973 7.512908 14.80632 0.3833315 3.796001 0.9778248 0.4869230 1.1208830 0.0000000 0.4825581 0.0000000 -6.82130582 0.07408333 0.150750 0.000000 -0.150750 0.057068929 0.004542376 TRUE TRUE
  • Note:
    • The comparisons made can be identified as “from ‘condition_1’ to ‘condition_2’”, meaning ‘condition_1’ is considered the ground state and ‘condition_2’ the changed state. This also means that a positive dIF value indicates that the isoform usage is increased in ‘condition_2’ compared to ‘condition_1’. Since the ‘isoformFeatures’ entry is the most relevant part of the switchAnalyzeRlist object, the most-used standard methods have also been implemented to work directly on isoformFeatures.

Help

Please Click HERE to learn more details about the results of IsoformSwitchAnalyzeR.

2 Differential Exon Usage

Counts

All exons whithin this gene region are shown and numbering below.

Expression

All exons whithin this gene region are shown and numbering below.

Splicing

All exons whithin this gene region are shown and numbering below.

Transcripts

All isoforms whithin this gene region are shown below.

Results

groupID featureID exonBaseMean dispersion pvalue padj seqnames start end width strand pgKDN.inf No.inf log2fold_No.inf_pgKDN.inf
ENSG00000168067 E001 8.6481707 0.008985037 0.001270999 0.01800159 11 64784918 64788817 3900 - 0.695 1.055 1.386
ENSG00000168067 E002 0.0000000       11 64788818 64788869 52 -      
ENSG00000168067 E003 0.2537694 0.016103796 0.528316234   11 64788870 64789046 177 - 0.000 0.135 10.816
ENSG00000168067 E004 0.4900381 0.016200882 0.552913686   11 64789047 64789136 90 - 0.220 0.135 -0.862
ENSG00000168067 E005 10.3900814 0.008497289 0.967554289 0.99341205 11 64789137 64789536 400 - 1.037 1.034 -0.014
ENSG00000168067 E006 6.4055563 0.041909424 0.404835413 0.68754584 11 64789537 64789624 88 - 0.917 0.809 -0.415
ENSG00000168067 E007 5.9688607 0.002457816 0.351926647 0.64206376 11 64789730 64789785 56 - 0.750 0.856 0.418
ENSG00000168067 E008 6.3286232 0.010043908 0.552474166 0.79603392 11 64789889 64789959 71 - 0.798 0.867 0.267
ENSG00000168067 E009 5.5673875 0.097210226 0.844799155 0.94467677 11 64790188 64790274 87 - 0.798 0.797 -0.005
ENSG00000168067 E010 2.9930589 0.004921214 0.272863040 0.56664458 11 64790394 64790450 57 - 0.474 0.630 0.723
ENSG00000168067 E011 0.9971399 0.012753343 0.527669134 0.77953422 11 64790451 64790462 12 - 0.220 0.320 0.723
ENSG00000168067 E012 2.8475409 0.005147657 0.946203686 0.98560295 11 64791909 64791957 49 - 0.561 0.571 0.045
ENSG00000168067 E013 4.6927721 0.003179000 0.604147434 0.82737132 11 64791958 64792086 129 - 0.775 0.714 -0.245
ENSG00000168067 E014 0.3795211 0.464193700 0.517327646   11 64792087 64792171 85 - 0.000 0.189 11.334
ENSG00000168067 E015 4.9637573 0.003568433 0.694081950 0.87492222 11 64792172 64792275 104 - 0.723 0.771 0.192
ENSG00000168067 E016 0.4901668 0.107662106 0.565854094   11 64792276 64792363 88 - 0.220 0.135 -0.862
ENSG00000168067 E017 4.0801328 0.003824651 0.912169283 0.97202289 11 64792364 64792422 59 - 0.695 0.682 -0.055
ENSG00000168067 E018 6.4396740 0.011905943 0.913564673 0.97274447 11 64796273 64796390 118 - 0.841 0.856 0.056
ENSG00000168067 E019 3.2256150 0.004605089 0.617659538 0.83450437 11 64796493 64796553 61 - 0.561 0.630 0.308
ENSG00000168067 E020 4.2345250 0.003527438 0.262749887 0.55553540 11 64796634 64796713 80 - 0.599 0.743 0.612
ENSG00000168067 E021 4.1347392 0.003665501 0.028641929 0.15847265 11 64796809 64796893 85 - 0.474 0.771 1.308
ENSG00000168067 E022 0.0000000       11 64796971 64796981 11 -      
ENSG00000168067 E023 2.6184166 0.006031208 0.253398595 0.54494995 11 64796982 64797023 42 - 0.423 0.592 0.816
ENSG00000168067 E024 2.2220554 0.006350475 0.761471027 0.90689974 11 64797104 64797150 47 - 0.520 0.477 -0.210
ENSG00000168067 E025 1.6984933 0.008490659 0.029660338 0.16191273 11 64797151 64797168 18 - 0.599 0.281 -1.710
ENSG00000168067 E026 1.2162242 0.152562581 0.171876805 0.44455758 11 64797169 64797192 24 - 0.474 0.237 -1.447
ENSG00000168067 E027 4.3084049 0.003867544 0.363552633 0.65241897 11 64797275 64797380 106 - 0.775 0.666 -0.447
ENSG00000168067 E028 0.3810317 0.038948295 0.285601902   11 64797381 64797424 44 - 0.000 0.189 11.381
ENSG00000168067 E029 0.5003641 0.036004882 0.689189902 0.87214379 11 64797425 64797500 76 - 0.124 0.189 0.723
ENSG00000168067 E030 2.4781188 0.006619508 0.966568457 0.99327230 11 64797501 64797519 19 - 0.520 0.526 0.031
ENSG00000168067 E031 2.3767902 0.010175142 0.177178253 0.45168897 11 64797520 64797534 15 - 0.365 0.571 1.045
ENSG00000168067 E032 2.4955517 0.007041898 0.318546047 0.61126173 11 64797626 64797664 39 - 0.423 0.571 0.723
ENSG00000168067 E033 2.8688443 0.005193734 0.338379727 0.63014407 11 64798794 64798837 44 - 0.474 0.611 0.640
ENSG00000168067 E034 3.4689640 0.105490753 0.957885516 0.98990594 11 64799421 64799479 59 - 0.634 0.630 -0.015
ENSG00000168067 E035 2.7238595 0.008432242 0.927966922 0.97862297 11 64799605 64799683 79 - 0.561 0.549 -0.055
ENSG00000168067 E036 1.6139398 0.008759673 0.725055142 0.88961736 11 64800109 64800175 67 - 0.365 0.421 0.308
ENSG00000168067 E037 1.5942382 0.008436263 0.429880655 0.70793886 11 64800176 64800181 6 - 0.474 0.356 -0.640
ENSG00000168067 E038 2.2128931 0.006584210 0.434187436 0.71143107 11 64800182 64800216 35 - 0.561 0.450 -0.540
ENSG00000168067 E039 2.4668834 0.005832203 0.673842375 0.86494151 11 64800311 64800335 25 - 0.561 0.502 -0.277
ENSG00000168067 E040 2.0963897 0.006988167 0.627696592 0.83998598 11 64800336 64800347 12 - 0.520 0.450 -0.348
ENSG00000168067 E041 1.9607203 0.087670155 0.334657192 0.62647603 11 64800348 64800392 45 - 0.561 0.390 -0.862
ENSG00000168067 E042 1.0880778 0.012043417 0.059652405 0.24488452 11 64800764 64800799 36 - 0.474 0.189 -1.862
ENSG00000168067 E043 1.3434876 0.009864678 0.200905392 0.48295736 11 64800800 64800826 27 - 0.474 0.281 -1.125
ENSG00000168067 E044 3.5813157 0.004732399 0.778584501 0.91492053 11 64800900 64801031 132 - 0.666 0.630 -0.152
ENSG00000168067 E045 2.4761081 0.006008469 0.967630871 0.99345548 11 64801111 64801183 73 - 0.520 0.526 0.031
ENSG00000168067 E046 1.4778025 0.009711115 0.657839087 0.85691946 11 64801579 64801621 43 - 0.423 0.356 -0.377
ENSG00000168067 E047 2.1936364 0.006857415 0.084155122 0.29955269 11 64801710 64801757 48 - 0.633 0.390 -1.184
ENSG00000168067 E048 0.0000000       11 64801758 64801813 56 -      
ENSG00000168067 E049 2.8094012 0.005492316 0.102610858 0.33489377 11 64802066 64802121 56 - 0.695 0.477 -0.988
ENSG00000168067 E050 2.0665949 0.007479138 0.051345118 0.22450786 11 64802419 64802483 65 - 0.633 0.356 -1.377
ENSG00000168067 E051 1.5854870 0.155825352 0.246504463 0.53715499 11 64802563 64802627 65 - 0.520 0.320 -1.084
ENSG00000168067 E052 1.2239671 0.198285439 0.378307912 0.66529365 11 64802628 64802630 3 - 0.423 0.281 -0.861
ENSG00000168067 E053 1.4773281 0.025744270 0.658143451 0.85707014 11 64802631 64802653 23 - 0.423 0.356 -0.377
ENSG00000168067 E054 1.3705825 0.010877039 0.567145738 0.80498008 11 64802885 64802942 58 - 0.299 0.390 0.553
ENSG00000168067 E055 0.0000000       11 64802943 64803053 111 -      
ENSG00000168067 E056 1.6050987 0.009026047 0.819585590 0.93441130 11 64803054 64803241 188 - 0.423 0.390 -0.184

Help

Please Click HERE to learn more details about the results from DEXseq.