ENSG00000168090

1 Isoform Switch

Summary Plot

Only the isoforms with fraction > 5% are shown below.

  • Note:

    • About the Coding Potential: Please check the spreadsheet in the “Results” tag to confirm the coding potential. The above figure only show the predicted coding potential. The “gene_biotype” in the result spreadsheet is from the database record. Therefore, if you find conflicts between “gene_biotype” and “codingPotential”, please trust the “gene_biotype”.

    • Notes on IDR and IDR_w_binding: As the prediction of Intrinsically Disordered Regions (IDR) and Intrinsically Disordered Binding Regions (IDBR) are done by two different tools we require two things to annotate the Intrinsically Disordered Binding Regions (IDBR). Firstly the IDBR (predicted by ANCHOR2) must be a region of at least 15 amino acids (after the smoothing). Secondly the fraction of the IDBR which overlaps the IDR predictions (done by IUPred3, again after smoothing) must be at least 80%. When that is the case the IDR type will be annotated as “IDR_w_binding_region” instead of just “IDR”. The current default parameters have not been rigorously tested and should be considered experimental.

    • For the function of any other domain, please Click HERE to search it through Pfam database.

Results

isoform_id gene_id condition_1 condition_2 gene_name gene_biotype iso_biotype gene_overall_mean gene_value_1 gene_value_2 gene_stderr_1 gene_stderr_2 gene_log2_fold_change iso_overall_mean iso_value_1 iso_value_2 iso_stderr_1 iso_stderr_2 iso_log2_fold_change IF_overall IF1 IF2 dIF isoform_switch_q_value gene_switch_q_value PTC codingPotential
ENST00000303904 ENSG00000168090 No_inf pgKDN_inf COPS6 protein_coding protein_coding 56.90997 50.56237 54.5179 0.7512873 1.146527 0.1086451 46.32895 38.31404 49.37186 1.909319 0.9528185 0.3657314 0.8218583 0.75705 0.9059 0.14885 0.002625716 0.002625716 FALSE TRUE
  • Note:
    • The comparisons made can be identified as “from ‘condition_1’ to ‘condition_2’”, meaning ‘condition_1’ is considered the ground state and ‘condition_2’ the changed state. This also means that a positive dIF value indicates that the isoform usage is increased in ‘condition_2’ compared to ‘condition_1’. Since the ‘isoformFeatures’ entry is the most relevant part of the switchAnalyzeRlist object, the most-used standard methods have also been implemented to work directly on isoformFeatures.

Help

Please Click HERE to learn more details about the results of IsoformSwitchAnalyzeR.

2 Differential Exon Usage

Counts

All exons whithin this gene region are shown and numbering below.

Expression

All exons whithin this gene region are shown and numbering below.

Splicing

All exons whithin this gene region are shown and numbering below.

Transcripts

All isoforms whithin this gene region are shown below.

Results

groupID featureID exonBaseMean dispersion pvalue padj seqnames start end width strand pgKDN.inf No.inf log2fold_No.inf_pgKDN.inf
ENSG00000168090 E001 0.3618970 0.0165874136 0.6014651745   7 100088969 100088974 6 + 0.171 0.096 -0.957
ENSG00000168090 E002 1.2044551 0.0106639231 0.2206701939 0.50760337 7 100088975 100088980 6 + 0.429 0.242 -1.179
ENSG00000168090 E003 2.0569960 0.0071507555 0.2497702760 0.54076954 7 100088981 100088981 1 + 0.563 0.396 -0.831
ENSG00000168090 E004 6.4698522 0.0682828925 0.7922728442 0.92065679 7 100088982 100088989 8 + 0.889 0.858 -0.119
ENSG00000168090 E005 6.4698522 0.0682828925 0.7922728442 0.92065679 7 100088990 100088992 3 + 0.889 0.858 -0.119
ENSG00000168090 E006 23.4513505 0.0006450696 0.2569676008 0.54920906 7 100088993 100089053 61 + 1.351 1.421 0.240
ENSG00000168090 E007 25.7332813 0.0005758243 0.6335357298 0.84328252 7 100089054 100089066 13 + 1.412 1.441 0.098
ENSG00000168090 E008 18.7545974 0.0007279838 0.6801596082 0.86792524 7 100089290 100089292 3 + 1.281 1.309 0.100
ENSG00000168090 E009 45.2131825 0.0003746590 0.3141755511 0.60727320 7 100089293 100089415 123 + 1.686 1.643 -0.144
ENSG00000168090 E010 0.3646686 0.2410069296 0.6520779973   7 100089416 100089614 199 + 0.171 0.096 -0.958
ENSG00000168090 E011 62.8445874 0.0013477448 0.0583132144 0.24179787 7 100089615 100089746 132 + 1.840 1.768 -0.244
ENSG00000168090 E012 5.8379512 0.0036022523 0.0041839221 0.04381663 7 100089747 100090361 615 + 0.641 0.964 1.280
ENSG00000168090 E013 0.8633608 0.0127507919 0.6825678507 0.86858482 7 100090362 100090398 37 + 0.236 0.300 0.458
ENSG00000168090 E014 25.4396883 0.0069429667 0.6406256278 0.84746881 7 100090399 100090427 29 + 1.436 1.408 -0.096
ENSG00000168090 E015 22.5213695 0.0043793548 0.9075854348 0.97066594 7 100090428 100090436 9 + 1.374 1.368 -0.020
ENSG00000168090 E016 39.7326144 0.0003670305 0.5503605321 0.79484576 7 100090437 100090487 51 + 1.623 1.597 -0.090
ENSG00000168090 E017 1.1423087 0.0108256536 0.0008877323 0.01369927 7 100090488 100090591 104 + 0.000 0.510 12.508
ENSG00000168090 E018 45.2660457 0.0003402360 0.8779413144 0.95851479 7 100090592 100090654 63 + 1.668 1.662 -0.019
ENSG00000168090 E019 2.4823388 0.0114242380 0.0665372422 0.25985660 7 100090655 100090901 247 + 0.389 0.651 1.265
ENSG00000168090 E020 35.2340366 0.0004222307 0.8098033024 0.92982259 7 100090902 100090949 48 + 1.565 1.554 -0.037
ENSG00000168090 E021 1.8773378 0.1171475270 0.0427997395 0.20166623 7 100090950 100091037 88 + 0.236 0.600 2.043
ENSG00000168090 E022 54.7505545 0.0002680060 0.7277820397 0.89131928 7 100091038 100091152 115 + 1.739 1.753 0.050
ENSG00000168090 E023 1.7429027 0.0090226237 0.0974291966 0.32521034 7 100091153 100091237 85 + 0.293 0.542 1.365
ENSG00000168090 E024 33.2507985 0.0004433414 0.5267900546 0.77897196 7 100091238 100091307 70 + 1.550 1.519 -0.106
ENSG00000168090 E025 19.5194919 0.0007754440 0.2745319778 0.56815194 7 100091308 100091330 23 + 1.347 1.276 -0.246
ENSG00000168090 E026 43.2110014 0.0003255094 0.9937233807 1.00000000 7 100091420 100091520 101 + 1.645 1.646 0.002
ENSG00000168090 E027 71.6680338 0.0002363452 0.0820062705 0.29466530 7 100091649 100092187 539 + 1.830 1.889 0.201

Help

Please Click HERE to learn more details about the results from DEXseq.