ENSG00000168268

1 Isoform Switch

Summary Plot

Only the isoforms with fraction > 5% are shown below.

  • Note:

    • About the Coding Potential: Please check the spreadsheet in the “Results” tag to confirm the coding potential. The above figure only show the predicted coding potential. The “gene_biotype” in the result spreadsheet is from the database record. Therefore, if you find conflicts between “gene_biotype” and “codingPotential”, please trust the “gene_biotype”.

    • Notes on IDR and IDR_w_binding: As the prediction of Intrinsically Disordered Regions (IDR) and Intrinsically Disordered Binding Regions (IDBR) are done by two different tools we require two things to annotate the Intrinsically Disordered Binding Regions (IDBR). Firstly the IDBR (predicted by ANCHOR2) must be a region of at least 15 amino acids (after the smoothing). Secondly the fraction of the IDBR which overlaps the IDR predictions (done by IUPred3, again after smoothing) must be at least 80%. When that is the case the IDR type will be annotated as “IDR_w_binding_region” instead of just “IDR”. The current default parameters have not been rigorously tested and should be considered experimental.

    • For the function of any other domain, please Click HERE to search it through Pfam database.

Results

isoform_id gene_id condition_1 condition_2 gene_name gene_biotype iso_biotype gene_overall_mean gene_value_1 gene_value_2 gene_stderr_1 gene_stderr_2 gene_log2_fold_change iso_overall_mean iso_value_1 iso_value_2 iso_stderr_1 iso_stderr_2 iso_log2_fold_change IF_overall IF1 IF2 dIF isoform_switch_q_value gene_switch_q_value PTC codingPotential
ENST00000422318 ENSG00000168268 No_inf pgKDN_inf NT5DC2 protein_coding protein_coding 116.937 75.19569 169.4011 2.842226 4.880578 1.171615 74.029605 35.990148 118.348982 1.1183135 3.4631959 1.71709445 0.60691667 0.482125 0.700650 0.218525 0.001933261 0.001933261 FALSE TRUE
ENST00000463947 ENSG00000168268 No_inf pgKDN_inf NT5DC2 protein_coding protein_coding 116.937 75.19569 169.4011 2.842226 4.880578 1.171615 25.132873 21.627783 32.977326 2.9891247 6.1574364 0.60835915 0.22475000 0.285900 0.192225 -0.093675 0.486731349 0.001933261 FALSE TRUE
ENST00000490681 ENSG00000168268 No_inf pgKDN_inf NT5DC2 protein_coding protein_coding_CDS_not_defined 116.937 75.19569 169.4011 2.842226 4.880578 1.171615 6.546588 6.485016 6.663182 0.6076363 0.4265124 0.03904168 0.06228333 0.086700 0.039400 -0.047300 0.156146221 0.001933261   FALSE
  • Note:
    • The comparisons made can be identified as “from ‘condition_1’ to ‘condition_2’”, meaning ‘condition_1’ is considered the ground state and ‘condition_2’ the changed state. This also means that a positive dIF value indicates that the isoform usage is increased in ‘condition_2’ compared to ‘condition_1’. Since the ‘isoformFeatures’ entry is the most relevant part of the switchAnalyzeRlist object, the most-used standard methods have also been implemented to work directly on isoformFeatures.

Help

Please Click HERE to learn more details about the results of IsoformSwitchAnalyzeR.

2 Differential Exon Usage

Counts

All exons whithin this gene region are shown and numbering below.

Expression

All exons whithin this gene region are shown and numbering below.

Splicing

All exons whithin this gene region are shown and numbering below.

Transcripts

All isoforms whithin this gene region are shown below.

Results

groupID featureID exonBaseMean dispersion pvalue padj seqnames start end width strand pgKDN.inf No.inf log2fold_No.inf_pgKDN.inf
ENSG00000168268 E001 0.0000000       3 52524385 52524386 2 -      
ENSG00000168268 E002 0.0000000       3 52524387 52524400 14 -      
ENSG00000168268 E003 0.0000000       3 52524401 52524469 69 -      
ENSG00000168268 E004 18.6208001 0.0070207178 2.370913e-01 5.260957e-01 3 52524470 52524522 53 - 1.230 1.320 0.318
ENSG00000168268 E005 60.2588139 0.0002477425 3.485737e-01 6.391556e-01 3 52524523 52524611 89 - 1.740 1.778 0.126
ENSG00000168268 E006 34.8776071 0.0009398021 8.709610e-01 9.556169e-01 3 52524612 52524612 1 - 1.518 1.525 0.027
ENSG00000168268 E007 102.5085683 0.0001627151 9.866018e-01 9.993874e-01 3 52524613 52524731 119 - 1.980 1.978 -0.006
ENSG00000168268 E008 82.7692027 0.0002616489 1.601710e-01 4.278229e-01 3 52524817 52524881 65 - 1.873 1.921 0.162
ENSG00000168268 E009 1.2617667 0.0100888030 6.062079e-05 1.556915e-03 3 52524882 52524962 81 - 0.063 0.648 4.460
ENSG00000168268 E010 97.6364226 0.0001788732 8.385390e-02 2.987454e-01 3 52524963 52525059 97 - 1.942 1.996 0.181
ENSG00000168268 E011 58.8916788 0.0009725889 5.160630e-01 7.718286e-01 3 52525060 52525103 44 - 1.734 1.761 0.090
ENSG00000168268 E012 83.8488017 0.0050723257 8.592804e-01 9.509963e-01 3 52525209 52525295 87 - 1.891 1.898 0.022
ENSG00000168268 E013 7.6207837 0.0017949102 2.596616e-05 7.694828e-04 3 52525296 52526491 1196 - 0.731 1.147 1.570
ENSG00000168268 E014 84.2710936 0.0002243756 9.695631e-01 9.937497e-01 3 52527294 52527375 82 - 1.896 1.894 -0.009
ENSG00000168268 E015 7.8271800 0.0098498426 2.205694e-03 2.750564e-02 3 52527376 52527616 241 - 0.790 1.109 1.200
ENSG00000168268 E016 88.3892027 0.0020480275 1.045392e-01 3.379245e-01 3 52527617 52527718 102 - 1.935 1.870 -0.220
ENSG00000168268 E017 2.8062104 0.0069132995 1.465999e-01 4.076740e-01 3 52527719 52527828 110 - 0.482 0.684 0.911
ENSG00000168268 E018 66.3058240 0.0003143684 1.628429e-01 4.313800e-01 3 52527829 52527931 103 - 1.810 1.752 -0.195
ENSG00000168268 E019 0.4980357 0.0260283714 6.132549e-02   3 52528007 52528012 6 - 0.063 0.332 2.875
ENSG00000168268 E020 25.4653661 0.0147820617 9.979604e-01 1.000000e+00 3 52528013 52528020 8 - 1.389 1.386 -0.009
ENSG00000168268 E021 52.4203556 0.0002875966 6.697915e-01 8.627784e-01 3 52528021 52528073 53 - 1.699 1.678 -0.069
ENSG00000168268 E022 0.0000000       3 52528074 52528074 1 -      
ENSG00000168268 E023 40.6924278 0.0003583428 4.760184e-01 7.426548e-01 3 52528183 52528191 9 - 1.597 1.559 -0.129
ENSG00000168268 E024 76.7702429 0.0018117153 9.141436e-01 9.729281e-01 3 52528192 52528311 120 - 1.858 1.852 -0.021
ENSG00000168268 E025 43.5050576 0.0003345958 1.760932e-01 4.502223e-01 3 52528446 52528511 66 - 1.593 1.657 0.217
ENSG00000168268 E026 30.7460084 0.0014559579 9.868739e-01 9.995478e-01 3 52528512 52528539 28 - 1.467 1.467 0.000
ENSG00000168268 E027 46.5668881 0.0119396010 3.724048e-01 6.603114e-01 3 52528637 52528692 56 - 1.659 1.602 -0.192
ENSG00000168268 E028 0.2459004 0.0165049362 4.833645e-01   3 52528693 52528765 73 - 0.063 0.141 1.290
ENSG00000168268 E029 48.3650960 0.0003192939 2.008368e-01 4.829217e-01 3 52528861 52528912 52 - 1.677 1.615 -0.210
ENSG00000168268 E030 39.1974554 0.0003929258 8.210412e-01 9.350145e-01 3 52528913 52528935 23 - 1.566 1.577 0.036
ENSG00000168268 E031 92.6797089 0.0009699406 3.349114e-02 1.741252e-01 3 52529150 52529334 185 - 1.959 1.881 -0.263
ENSG00000168268 E032 2.2164852 0.0154913014 2.247887e-02 1.363445e-01 3 52529889 52529944 56 - 0.353 0.684 1.612
ENSG00000168268 E033 9.5899066 0.0014867655 1.830878e-06 7.874525e-05 3 52532163 52532514 352 - 0.811 1.242 1.587
ENSG00000168268 E034 72.8795025 0.0025025805 5.350597e-05 1.410455e-03 3 52533506 52533857 352 - 1.882 1.699 -0.617
ENSG00000168268 E035 0.3628435 0.0166306090 8.482276e-01   3 52534210 52534350 141 - 0.118 0.141 0.290
ENSG00000168268 E036 0.1170040 0.0116827545 1.000000e+00   3 52534351 52534532 182 - 0.063 0.000 -8.632
ENSG00000168268 E037 0.1265070 0.0123588080 1.981515e-01   3 52534533 52535054 522 - 0.000 0.141 11.107

Help

Please Click HERE to learn more details about the results from DEXseq.