ENSG00000168297

1 Isoform Switch

Summary Plot

Only the isoforms with fraction > 5% are shown below.

  • Note:

    • About the Coding Potential: Please check the spreadsheet in the “Results” tag to confirm the coding potential. The above figure only show the predicted coding potential. The “gene_biotype” in the result spreadsheet is from the database record. Therefore, if you find conflicts between “gene_biotype” and “codingPotential”, please trust the “gene_biotype”.

    • Notes on IDR and IDR_w_binding: As the prediction of Intrinsically Disordered Regions (IDR) and Intrinsically Disordered Binding Regions (IDBR) are done by two different tools we require two things to annotate the Intrinsically Disordered Binding Regions (IDBR). Firstly the IDBR (predicted by ANCHOR2) must be a region of at least 15 amino acids (after the smoothing). Secondly the fraction of the IDBR which overlaps the IDR predictions (done by IUPred3, again after smoothing) must be at least 80%. When that is the case the IDR type will be annotated as “IDR_w_binding_region” instead of just “IDR”. The current default parameters have not been rigorously tested and should be considered experimental.

    • For the function of any other domain, please Click HERE to search it through Pfam database.

Results

isoform_id gene_id condition_1 condition_2 gene_name gene_biotype iso_biotype gene_overall_mean gene_value_1 gene_value_2 gene_stderr_1 gene_stderr_2 gene_log2_fold_change iso_overall_mean iso_value_1 iso_value_2 iso_stderr_1 iso_stderr_2 iso_log2_fold_change IF_overall IF1 IF2 dIF isoform_switch_q_value gene_switch_q_value PTC codingPotential
ENST00000302779 ENSG00000168297 No_inf pgKDN_inf PXK protein_coding protein_coding 10.57456 13.02181 9.574131 0.2434611 0.6726995 -0.4433184 1.4225290 0.0000000 3.2859558 0.0000000 1.5538303 8.3645531 0.14884167 0.000000 0.320875 0.320875 0.02790741 0.02790741 FALSE TRUE
ENST00000356151 ENSG00000168297 No_inf pgKDN_inf PXK protein_coding protein_coding 10.57456 13.02181 9.574131 0.2434611 0.6726995 -0.4433184 2.7201357 2.1213972 1.8472278 1.2248328 1.1110358 -0.1986487 0.27060000 0.164725 0.212275 0.047550 1.00000000 0.02790741 FALSE TRUE
ENST00000383715 ENSG00000168297 No_inf pgKDN_inf PXK protein_coding protein_coding 10.57456 13.02181 9.574131 0.2434611 0.6726995 -0.4433184 0.6496293 1.0299920 0.4056493 0.5950000 0.2995872 -1.3231337 0.05957500 0.081375 0.038575 -0.042800 0.94534478 0.02790741 FALSE TRUE
ENST00000468776 ENSG00000168297 No_inf pgKDN_inf PXK protein_coding nonsense_mediated_decay 10.57456 13.02181 9.574131 0.2434611 0.6726995 -0.4433184 0.7197390 1.3947598 0.7644571 1.3947598 0.7644571 -0.8590661 0.06492500 0.110275 0.084500 -0.025775 0.99630167 0.02790741 FALSE TRUE
ENST00000479134 ENSG00000168297 No_inf pgKDN_inf PXK protein_coding protein_coding 10.57456 13.02181 9.574131 0.2434611 0.6726995 -0.4433184 1.2920670 2.3971413 0.8928547 1.4172740 0.8928547 -1.4147551 0.11097500 0.185700 0.078325 -0.107375 0.83425739 0.02790741 FALSE TRUE
ENST00000493474 ENSG00000168297 No_inf pgKDN_inf PXK protein_coding protein_coding 10.57456 13.02181 9.574131 0.2434611 0.6726995 -0.4433184 0.4980643 0.7555095 0.0000000 0.7555095 0.0000000 -6.2583484 0.04021667 0.055225 0.000000 -0.055225 0.88529709 0.02790741   FALSE
MSTRG.20305.7 ENSG00000168297 No_inf pgKDN_inf PXK protein_coding   10.57456 13.02181 9.574131 0.2434611 0.6726995 -0.4433184 2.2245450 3.2239245 1.6620768 1.7125272 0.9652727 -0.9516449 0.21290833 0.242825 0.188500 -0.054325 0.86217975 0.02790741 FALSE TRUE
  • Note:
    • The comparisons made can be identified as “from ‘condition_1’ to ‘condition_2’”, meaning ‘condition_1’ is considered the ground state and ‘condition_2’ the changed state. This also means that a positive dIF value indicates that the isoform usage is increased in ‘condition_2’ compared to ‘condition_1’. Since the ‘isoformFeatures’ entry is the most relevant part of the switchAnalyzeRlist object, the most-used standard methods have also been implemented to work directly on isoformFeatures.

Help

Please Click HERE to learn more details about the results of IsoformSwitchAnalyzeR.

2 Differential Exon Usage

Counts

All exons whithin this gene region are shown and numbering below.

Expression

All exons whithin this gene region are shown and numbering below.

Splicing

All exons whithin this gene region are shown and numbering below.

Transcripts

All isoforms whithin this gene region are shown below.

Results

groupID featureID exonBaseMean dispersion pvalue padj seqnames start end width strand pgKDN.inf No.inf log2fold_No.inf_pgKDN.inf
ENSG00000168297 E001 0.0000000       3 58332880 58332884 5 +      
ENSG00000168297 E002 0.0000000       3 58332885 58332889 5 +      
ENSG00000168297 E003 0.0000000       3 58332890 58332891 2 +      
ENSG00000168297 E004 0.0000000       3 58332892 58332897 6 +      
ENSG00000168297 E005 0.1268540 0.0123305160 0.723465861   3 58332898 58332902 5 + 0.000 0.084 8.420
ENSG00000168297 E006 0.2438580 0.0162194835 0.816779263   3 58332903 58332909 7 + 0.108 0.084 -0.407
ENSG00000168297 E007 0.4795001 0.0175607830 0.197155248   3 58332910 58332910 1 + 0.266 0.084 -1.992
ENSG00000168297 E008 1.2238457 0.0107844373 0.640173853 0.84709516 3 58332911 58332933 23 + 0.382 0.314 -0.407
ENSG00000168297 E009 1.3506997 0.0105802233 0.848690275 0.94638312 3 58332934 58332947 14 + 0.382 0.357 -0.144
ENSG00000168297 E010 1.9472688 0.0951759460 0.357722260 0.64723131 3 58332948 58332986 39 + 0.548 0.396 -0.769
ENSG00000168297 E011 3.6748092 0.0076716869 0.422062009 0.70132147 3 58332987 58333090 104 + 0.718 0.622 -0.407
ENSG00000168297 E012 0.0000000       3 58333306 58333624 319 +      
ENSG00000168297 E013 2.1879735 0.0066274284 0.117938132 0.36273239 3 58365874 58365924 51 + 0.613 0.396 -1.059
ENSG00000168297 E014 3.2008206 0.0374539827 0.992790774 1.00000000 3 58369431 58369478 48 + 0.613 0.622 0.040
ENSG00000168297 E015 9.8310392 0.0017034825 0.663786647 0.86015275 3 58382514 58382700 187 + 1.047 1.015 -0.118
ENSG00000168297 E016 6.0956235 0.0243798791 0.093401813 0.31772522 3 58390582 58390659 78 + 0.949 0.754 -0.755
ENSG00000168297 E017 4.9098595 0.0219770642 0.566227991 0.80460915 3 58391147 58391220 74 + 0.803 0.737 -0.263
ENSG00000168297 E018 4.6409384 0.0038426575 0.118692134 0.36401351 3 58391773 58391847 75 + 0.840 0.664 -0.712
ENSG00000168297 E019 7.5252244 0.0402078524 0.838941514 0.94219637 3 58394998 58395102 105 + 0.906 0.937 0.119
ENSG00000168297 E020 4.9691394 0.0031435489 0.102526766 0.33476684 3 58395658 58395673 16 + 0.642 0.842 0.815
ENSG00000168297 E021 9.3655632 0.0019326261 0.752068334 0.90241566 3 58395674 58395759 86 + 0.988 1.024 0.130
ENSG00000168297 E022 8.8242164 0.0026194004 0.302450983 0.59552677 3 58397039 58397137 99 + 1.036 0.948 -0.327
ENSG00000168297 E023 7.0850629 0.0022067227 0.096007390 0.32272126 3 58397138 58397200 63 + 0.988 0.829 -0.606
ENSG00000168297 E024 11.3431312 0.0013606059 0.800792012 0.92561060 3 58397605 58397722 118 + 1.069 1.096 0.100
ENSG00000168297 E025 7.9060854 0.0022181341 0.407483079 0.68998215 3 58399299 58399377 79 + 0.890 0.978 0.330
ENSG00000168297 E026 5.9930894 0.0028056712 0.236844989 0.52578707 3 58403862 58403910 49 + 0.906 0.785 -0.466
ENSG00000168297 E027 6.3329959 0.0035478963 0.058560008 0.24244077 3 58408924 58408978 55 + 0.963 0.770 -0.742
ENSG00000168297 E028 5.0009873 0.0055106127 0.162689994 0.43129031 3 58408979 58409001 23 + 0.857 0.702 -0.619
ENSG00000168297 E029 9.3425032 0.0019250452 0.884119834 0.96104401 3 58409532 58409615 84 + 1.013 1.006 -0.025
ENSG00000168297 E030 4.4594935 0.0037731629 0.259038206 0.55160165 3 58409616 58409618 3 + 0.642 0.785 0.593
ENSG00000168297 E031 6.5564505 0.0082714102 0.338502397 0.63023234 3 58410090 58410159 70 + 0.803 0.915 0.432
ENSG00000168297 E032 1.4779548 0.0283802649 0.958528359 0.99016047 3 58412901 58412903 3 + 0.382 0.396 0.078
ENSG00000168297 E033 4.3123932 0.0262857197 0.977139342 0.99644601 3 58412904 58412963 60 + 0.718 0.720 0.008
ENSG00000168297 E034 3.1439211 0.1941633851 0.050259431 0.22151607 3 58412964 58414527 1564 + 0.328 0.738 1.985
ENSG00000168297 E035 1.1416794 0.0112018043 0.003785059 0.04091601 3 58420536 58420538 3 + 0.000 0.464 13.457
ENSG00000168297 E036 1.2586834 0.0105462676 0.024380634 0.14317782 3 58420539 58420568 30 + 0.108 0.464 2.763
ENSG00000168297 E037 4.3260623 0.0033973600 0.513983553 0.77078769 3 58420569 58420960 392 + 0.669 0.754 0.352
ENSG00000168297 E038 0.6342667 0.0142579904 0.044879663 0.20707905 3 58423461 58423494 34 + 0.000 0.314 12.746
ENSG00000168297 E039 72.5305307 0.0002909024 0.121395881 0.36877902 3 58424752 58426183 1432 + 1.828 1.881 0.180

Help

Please Click HERE to learn more details about the results from DEXseq.