ENSG00000168300

1 Isoform Switch

Summary Plot

Only the isoforms with fraction > 5% are shown below.

  • Note:

    • About the Coding Potential: Please check the spreadsheet in the “Results” tag to confirm the coding potential. The above figure only show the predicted coding potential. The “gene_biotype” in the result spreadsheet is from the database record. Therefore, if you find conflicts between “gene_biotype” and “codingPotential”, please trust the “gene_biotype”.

    • Notes on IDR and IDR_w_binding: As the prediction of Intrinsically Disordered Regions (IDR) and Intrinsically Disordered Binding Regions (IDBR) are done by two different tools we require two things to annotate the Intrinsically Disordered Binding Regions (IDBR). Firstly the IDBR (predicted by ANCHOR2) must be a region of at least 15 amino acids (after the smoothing). Secondly the fraction of the IDBR which overlaps the IDR predictions (done by IUPred3, again after smoothing) must be at least 80%. When that is the case the IDR type will be annotated as “IDR_w_binding_region” instead of just “IDR”. The current default parameters have not been rigorously tested and should be considered experimental.

    • For the function of any other domain, please Click HERE to search it through Pfam database.

Results

isoform_id gene_id condition_1 condition_2 gene_name gene_biotype iso_biotype gene_overall_mean gene_value_1 gene_value_2 gene_stderr_1 gene_stderr_2 gene_log2_fold_change iso_overall_mean iso_value_1 iso_value_2 iso_stderr_1 iso_stderr_2 iso_log2_fold_change IF_overall IF1 IF2 dIF isoform_switch_q_value gene_switch_q_value PTC codingPotential
ENST00000522514 ENSG00000168300 No_inf pgKDN_inf PCMTD1 protein_coding protein_coding 14.48049 23.11951 11.73608 0.504702 0.713276 -0.977556 6.7869250 8.4205135 7.6978873 1.1732112 1.1611707 -0.129285 0.51739167 0.363350 0.676600 0.313250 0.26452342 0.01153327 FALSE TRUE
ENST00000544451 ENSG00000168300 No_inf pgKDN_inf PCMTD1 protein_coding protein_coding 14.48049 23.11951 11.73608 0.504702 0.713276 -0.977556 4.6549211 10.9590203 0.7680353 1.1903823 0.7680353 -3.817455 0.25971667 0.474625 0.064575 -0.410050 0.01153327 0.01153327 FALSE TRUE
MSTRG.27650.4 ENSG00000168300 No_inf pgKDN_inf PCMTD1 protein_coding   14.48049 23.11951 11.73608 0.504702 0.713276 -0.977556 0.8843415 0.4195342 1.3002857 0.4195342 1.3002857 1.609037 0.07708333 0.018825 0.096450 0.077625 0.92254139 0.01153327 FALSE TRUE
  • Note:
    • The comparisons made can be identified as “from ‘condition_1’ to ‘condition_2’”, meaning ‘condition_1’ is considered the ground state and ‘condition_2’ the changed state. This also means that a positive dIF value indicates that the isoform usage is increased in ‘condition_2’ compared to ‘condition_1’. Since the ‘isoformFeatures’ entry is the most relevant part of the switchAnalyzeRlist object, the most-used standard methods have also been implemented to work directly on isoformFeatures.

Help

Please Click HERE to learn more details about the results of IsoformSwitchAnalyzeR.

2 Differential Exon Usage

Counts

All exons whithin this gene region are shown and numbering below.

Expression

All exons whithin this gene region are shown and numbering below.

Splicing

All exons whithin this gene region are shown and numbering below.

Transcripts

All isoforms whithin this gene region are shown below.

Results

groupID featureID exonBaseMean dispersion pvalue padj seqnames start end width strand pgKDN.inf No.inf log2fold_No.inf_pgKDN.inf
ENSG00000168300 E001 0.000000       8 51817575 51817579 5 -      
ENSG00000168300 E002 0.000000       8 51817580 51817582 3 -      
ENSG00000168300 E003 1.752374 0.2681692063 6.298479e-01 8.412426e-01 8 51817583 51817617 35 - 0.319 0.451 0.747
ENSG00000168300 E004 206.673919 0.0001088626 2.280044e-06 9.481256e-05 8 51817618 51820146 2529 - 2.231 2.298 0.224
ENSG00000168300 E005 41.007062 0.0167256861 5.931773e-01 8.206764e-01 8 51820147 51820718 572 - 1.610 1.575 -0.119
ENSG00000168300 E006 2.467067 0.0060145009 4.280578e-01 7.065607e-01 8 51826929 51827361 433 - 0.590 0.475 -0.541
ENSG00000168300 E007 15.605670 0.0010198436 4.090524e-01 6.913117e-01 8 51831444 51831567 124 - 1.228 1.164 -0.228
ENSG00000168300 E008 17.627936 0.0041295030 1.734950e-02 1.153368e-01 8 51833518 51833689 172 - 1.349 1.174 -0.616
ENSG00000168300 E009 1.014356 0.0137408530 3.382377e-02 1.750217e-01 8 51839447 51839638 192 - 0.000 0.367 11.383
ENSG00000168300 E010 3.489864 0.0040547662 4.519571e-01 7.251265e-01 8 51844809 51845660 852 - 0.548 0.651 0.459
ENSG00000168300 E011 8.718185 0.0016649926 8.470393e-03 7.185312e-02 8 51845661 51845763 103 - 1.112 0.863 -0.922
ENSG00000168300 E012 2.277821 0.0130080616 7.339360e-03 6.518048e-02 8 51848945 51850086 1142 - 0.134 0.582 2.962
ENSG00000168300 E013 1.107597 0.0109250280 4.215761e-01 7.007515e-01 8 51860486 51860844 359 - 0.389 0.262 -0.804
ENSG00000168300 E014 4.308194 0.0054243142 1.651405e-01 4.346635e-01 8 51860845 51860860 16 - 0.808 0.635 -0.711
ENSG00000168300 E015 18.270413 0.0032481880 3.571456e-02 1.811728e-01 8 51860861 51861246 386 - 1.349 1.197 -0.533
ENSG00000168300 E016 0.000000       8 51870248 51870390 143 -      
ENSG00000168300 E017 4.989430 0.0270743367 5.577931e-04 9.514236e-03 8 51898930 51899186 257 - 1.002 0.562 -1.770

Help

Please Click HERE to learn more details about the results from DEXseq.