ENSG00000168385

1 Isoform Switch

Summary Plot

Only the isoforms with fraction > 5% are shown below.

  • Note:

    • About the Coding Potential: Please check the spreadsheet in the “Results” tag to confirm the coding potential. The above figure only show the predicted coding potential. The “gene_biotype” in the result spreadsheet is from the database record. Therefore, if you find conflicts between “gene_biotype” and “codingPotential”, please trust the “gene_biotype”.

    • Notes on IDR and IDR_w_binding: As the prediction of Intrinsically Disordered Regions (IDR) and Intrinsically Disordered Binding Regions (IDBR) are done by two different tools we require two things to annotate the Intrinsically Disordered Binding Regions (IDBR). Firstly the IDBR (predicted by ANCHOR2) must be a region of at least 15 amino acids (after the smoothing). Secondly the fraction of the IDBR which overlaps the IDR predictions (done by IUPred3, again after smoothing) must be at least 80%. When that is the case the IDR type will be annotated as “IDR_w_binding_region” instead of just “IDR”. The current default parameters have not been rigorously tested and should be considered experimental.

    • For the function of any other domain, please Click HERE to search it through Pfam database.

Results

isoform_id gene_id condition_1 condition_2 gene_name gene_biotype iso_biotype gene_overall_mean gene_value_1 gene_value_2 gene_stderr_1 gene_stderr_2 gene_log2_fold_change iso_overall_mean iso_value_1 iso_value_2 iso_stderr_1 iso_stderr_2 iso_log2_fold_change IF_overall IF1 IF2 dIF isoform_switch_q_value gene_switch_q_value PTC codingPotential
ENST00000391971 ENSG00000168385 No_inf pgKDN_inf SEPTIN2 protein_coding protein_coding 194.2805 216.9559 192.9487 4.874518 10.4433 -0.1691765 73.51600 58.443000 89.69023 7.286014 1.025330 0.6178346 0.38602500 0.268025 0.468350 0.200325 0.001207257 0.001207257 FALSE TRUE
ENST00000441533 ENSG00000168385 No_inf pgKDN_inf SEPTIN2 protein_coding protein_coding 194.2805 216.9559 192.9487 4.874518 10.4433 -0.1691765 11.39662 7.516523 13.11209 7.516523 7.576762 0.8019419 0.05540833 0.032525 0.062975 0.030450 0.837094506 0.001207257   FALSE
ENST00000451310 ENSG00000168385 No_inf pgKDN_inf SEPTIN2 protein_coding protein_coding 194.2805 216.9559 192.9487 4.874518 10.4433 -0.1691765 61.31702 82.921623 52.11650 6.756682 8.054345 -0.6699053 0.31042500 0.381850 0.266825 -0.115025 0.260242044 0.001207257   FALSE
  • Note:
    • The comparisons made can be identified as “from ‘condition_1’ to ‘condition_2’”, meaning ‘condition_1’ is considered the ground state and ‘condition_2’ the changed state. This also means that a positive dIF value indicates that the isoform usage is increased in ‘condition_2’ compared to ‘condition_1’. Since the ‘isoformFeatures’ entry is the most relevant part of the switchAnalyzeRlist object, the most-used standard methods have also been implemented to work directly on isoformFeatures.

Help

Please Click HERE to learn more details about the results of IsoformSwitchAnalyzeR.

2 Differential Exon Usage

Counts

All exons whithin this gene region are shown and numbering below.

Expression

All exons whithin this gene region are shown and numbering below.

Splicing

All exons whithin this gene region are shown and numbering below.

Transcripts

All isoforms whithin this gene region are shown below.

Results

groupID featureID exonBaseMean dispersion pvalue padj seqnames start end width strand pgKDN.inf No.inf log2fold_No.inf_pgKDN.inf
ENSG00000168385 E001 0.0000000       2 241315100 241315269 170 +      
ENSG00000168385 E002 0.0000000       2 241315270 241315288 19 +      
ENSG00000168385 E003 0.9518843 0.0119900005 0.0191682008 0.12355845 2 241315289 241315354 66 + 0.442 0.092 -2.899
ENSG00000168385 E004 3.0375457 0.0049400130 0.2226061471 0.50996532 2 241315355 241315446 92 + 0.680 0.528 -0.677
ENSG00000168385 E005 3.4203011 0.0052271881 0.5383194202 0.78712544 2 241315447 241315610 164 + 0.680 0.611 -0.299
ENSG00000168385 E006 0.0000000       2 241315861 241315863 3 +      
ENSG00000168385 E007 0.0000000       2 241315864 241315874 11 +      
ENSG00000168385 E008 0.0000000       2 241315875 241315881 7 +      
ENSG00000168385 E009 0.0000000       2 241315882 241315882 1 +      
ENSG00000168385 E010 0.0000000       2 241315883 241315893 11 +      
ENSG00000168385 E011 0.0000000       2 241315894 241315900 7 +      
ENSG00000168385 E012 0.0000000       2 241315901 241315903 3 +      
ENSG00000168385 E013 0.0000000       2 241315904 241315904 1 +      
ENSG00000168385 E014 0.0000000       2 241315905 241315905 1 +      
ENSG00000168385 E015 0.1176306 0.0117398907 0.4900718730   2 241315906 241315912 7 + 0.098 0.000 -11.715
ENSG00000168385 E016 0.3623976 0.1494045078 0.5600894062   2 241315913 241315914 2 + 0.178 0.092 -1.092
ENSG00000168385 E017 1.7320386 0.0089249529 0.3738897473 0.66157179 2 241315915 241315920 6 + 0.355 0.496 0.756
ENSG00000168385 E018 2.9928941 0.0180895062 0.0299026154 0.16263670 2 241315921 241315923 3 + 0.401 0.722 1.493
ENSG00000168385 E019 2.9928941 0.0180895062 0.0299026154 0.16263670 2 241315924 241315924 1 + 0.401 0.722 1.493
ENSG00000168385 E020 2.9928941 0.0180895062 0.0299026154 0.16263670 2 241315925 241315927 3 + 0.401 0.722 1.493
ENSG00000168385 E021 3.9795859 0.0432207308 0.0560012128 0.23581897 2 241315928 241315934 7 + 0.515 0.810 1.261
ENSG00000168385 E022 4.1064399 0.0303406781 0.0333018993 0.17345289 2 241315935 241315935 1 + 0.515 0.825 1.323
ENSG00000168385 E023 6.3311973 0.0026994227 0.0199991686 0.12695998 2 241315936 241315943 8 + 0.703 0.968 1.037
ENSG00000168385 E024 6.4580512 0.0023276827 0.0145493093 0.10291863 2 241315944 241315945 2 + 0.703 0.979 1.078
ENSG00000168385 E025 7.3383133 0.0018636839 0.0035185360 0.03889031 2 241315946 241315950 5 + 0.724 1.040 1.213
ENSG00000168385 E026 7.4651672 0.0018135325 0.0025179679 0.03027287 2 241315951 241315952 2 + 0.724 1.049 1.247
ENSG00000168385 E027 12.5723921 0.0010523822 0.1934003578 0.47315499 2 241315953 241315958 6 + 1.065 1.183 0.423
ENSG00000168385 E028 23.1811001 0.0016493774 0.7861140959 0.91758390 2 241315959 241315982 24 + 1.385 1.380 -0.016
ENSG00000168385 E029 0.1271363 0.0123043794 0.5904284088   2 241316003 241316169 167 + 0.000 0.092 10.952
ENSG00000168385 E030 1.9763696 0.0069906866 0.4191872051 0.69875916 2 241316170 241316315 146 + 0.401 0.528 0.645
ENSG00000168385 E031 1.3673762 0.0095964160 0.1717541539 0.44439379 2 241316316 241316421 106 + 0.245 0.462 1.323
ENSG00000168385 E032 1.3700203 0.0111736977 0.1729096678 0.44586489 2 241316422 241316429 8 + 0.245 0.462 1.323
ENSG00000168385 E033 3.1015908 0.0058562739 0.1182895094 0.36333655 2 241316430 241316482 53 + 0.480 0.702 0.995
ENSG00000168385 E034 3.2018838 0.0379403926 0.6237850090 0.83809347 2 241316483 241316540 58 + 0.577 0.659 0.356
ENSG00000168385 E035 1.3606439 0.0096771631 0.4554861960 0.72797346 2 241316541 241316550 10 + 0.303 0.425 0.715
ENSG00000168385 E036 1.3606439 0.0096771631 0.4554861960 0.72797346 2 241316551 241316555 5 + 0.303 0.425 0.715
ENSG00000168385 E037 0.4996088 0.0152398400 0.3663812565   2 241316556 241316575 20 + 0.098 0.233 1.493
ENSG00000168385 E038 14.5435811 0.0009348182 0.1317703312 0.38513526 2 241317499 241317599 101 + 1.118 1.245 0.452
ENSG00000168385 E039 0.6162956 0.0184368741 0.7336528900 0.89417614 2 241318237 241318344 108 + 0.178 0.233 0.493
ENSG00000168385 E040 1.1157134 0.0130108197 0.3908406199 0.67612657 2 241320203 241320287 85 + 0.245 0.384 0.908
ENSG00000168385 E041 1.2235925 0.0683184568 0.8976469813 0.96625659 2 241324154 241324215 62 + 0.355 0.340 -0.092
ENSG00000168385 E042 32.7091347 0.0030219799 0.4467860047 0.72107768 2 241324216 241324241 26 + 1.542 1.512 -0.103
ENSG00000168385 E043 6.1108719 0.0077153698 0.5570173434 0.79916951 2 241324409 241324662 254 + 0.879 0.825 -0.208
ENSG00000168385 E044 2.3408770 0.0059936916 0.6316363283 0.84198619 2 241324663 241325244 582 + 0.480 0.557 0.367
ENSG00000168385 E045 0.3809703 0.0288590241 0.1244194005   2 241325967 241325992 26 + 0.000 0.233 12.369
ENSG00000168385 E046 67.9012714 0.0021594895 0.0124393881 0.09247498 2 241325993 241326113 121 + 1.883 1.794 -0.300
ENSG00000168385 E047 1.1244371 0.0108252010 0.1184457167 0.36354719 2 241329644 241329738 95 + 0.178 0.425 1.715
ENSG00000168385 E048 65.7297014 0.0002294219 0.0138615278 0.09934985 2 241335126 241335212 87 + 1.863 1.785 -0.264
ENSG00000168385 E049 0.7515530 0.0141268389 0.1167066806 0.36042477 2 241335213 241335321 109 + 0.098 0.340 2.230
ENSG00000168385 E050 0.5080420 0.0158425591 0.0559838408 0.23580105 2 241335322 241335351 30 + 0.000 0.290 12.872
ENSG00000168385 E051 3.5925371 0.0644265473 0.2199028756 0.50656406 2 241335352 241335640 289 + 0.547 0.741 0.834
ENSG00000168385 E052 1.6416352 0.0081237690 0.0018241795 0.02376584 2 241335843 241335945 103 + 0.098 0.585 3.493
ENSG00000168385 E053 0.6261805 0.0149412296 0.2074358473 0.49101792 2 241335946 241335958 13 + 0.098 0.290 1.908
ENSG00000168385 E054 0.8713906 0.0335370198 0.3156471498 0.60848639 2 241335959 241335974 16 + 0.178 0.340 1.230
ENSG00000168385 E055 81.1233089 0.0001933322 0.0035590123 0.03918983 2 241335975 241336098 124 + 1.956 1.872 -0.284
ENSG00000168385 E056 3.6071719 0.0789911974 0.0755639305 0.28079487 2 241336099 241336381 283 + 0.480 0.776 1.300
ENSG00000168385 E057 4.6072499 0.1203989313 0.1218078166 0.36939510 2 241336785 241337098 314 + 0.578 0.855 1.148
ENSG00000168385 E058 2.7480354 0.1912286959 0.1171188179 0.36134582 2 241337311 241337381 71 + 0.355 0.701 1.672
ENSG00000168385 E059 71.9822600 0.0011397405 0.0345825801 0.17768666 2 241337382 241337475 94 + 1.897 1.830 -0.224
ENSG00000168385 E060 51.1073100 0.0003134966 0.0023478232 0.02876590 2 241337476 241337516 41 + 1.774 1.659 -0.389
ENSG00000168385 E061 5.7301996 0.0024867476 0.0030455127 0.03489823 2 241337517 241337672 156 + 0.606 0.957 1.410
ENSG00000168385 E062 60.8829233 0.0066464937 0.1184448802 0.36354719 2 241337673 241337719 47 + 1.824 1.759 -0.220
ENSG00000168385 E063 64.1790333 0.0051995761 0.0898317805 0.31135449 2 241337720 241337790 71 + 1.848 1.780 -0.230
ENSG00000168385 E064 82.8939113 0.0028609313 0.0548201296 0.23323096 2 241342992 241343093 102 + 1.955 1.892 -0.211
ENSG00000168385 E065 100.7635948 0.0001931885 0.0971935724 0.32472515 2 241343752 241343897 146 + 2.026 1.989 -0.124
ENSG00000168385 E066 75.5733766 0.0002041050 0.2288660302 0.51757560 2 241346166 241346249 84 + 1.898 1.869 -0.097
ENSG00000168385 E067 3.0107397 0.0065628872 0.0016937751 0.02245626 2 241346250 241346602 353 + 0.303 0.759 2.230
ENSG00000168385 E068 77.0386355 0.0017172154 0.0322560122 0.16994772 2 241348134 241348191 58 + 1.926 1.858 -0.230
ENSG00000168385 E069 59.3790544 0.0141250723 0.3481108389 0.63857011 2 241350073 241350086 14 + 1.802 1.759 -0.146
ENSG00000168385 E070 109.8937745 0.0016873809 0.3303873092 0.62288567 2 241350087 241350203 117 + 2.054 2.035 -0.063
ENSG00000168385 E071 2.3591921 0.0715623243 0.2248423687 0.51238637 2 241351943 241351966 24 + 0.401 0.611 1.023
ENSG00000168385 E072 1650.5359538 0.0010476075 0.0008073701 0.01269895 2 241351967 241354027 2061 + 3.196 3.234 0.127

Help

Please Click HERE to learn more details about the results from DEXseq.