ENSG00000168389

1 Isoform Switch

Summary Plot

Only the isoforms with fraction > 5% are shown below.

  • Note:

    • About the Coding Potential: Please check the spreadsheet in the “Results” tag to confirm the coding potential. The above figure only show the predicted coding potential. The “gene_biotype” in the result spreadsheet is from the database record. Therefore, if you find conflicts between “gene_biotype” and “codingPotential”, please trust the “gene_biotype”.

    • Notes on IDR and IDR_w_binding: As the prediction of Intrinsically Disordered Regions (IDR) and Intrinsically Disordered Binding Regions (IDBR) are done by two different tools we require two things to annotate the Intrinsically Disordered Binding Regions (IDBR). Firstly the IDBR (predicted by ANCHOR2) must be a region of at least 15 amino acids (after the smoothing). Secondly the fraction of the IDBR which overlaps the IDR predictions (done by IUPred3, again after smoothing) must be at least 80%. When that is the case the IDR type will be annotated as “IDR_w_binding_region” instead of just “IDR”. The current default parameters have not been rigorously tested and should be considered experimental.

    • For the function of any other domain, please Click HERE to search it through Pfam database.

Results

isoform_id gene_id condition_1 condition_2 gene_name gene_biotype iso_biotype gene_overall_mean gene_value_1 gene_value_2 gene_stderr_1 gene_stderr_2 gene_log2_fold_change iso_overall_mean iso_value_1 iso_value_2 iso_stderr_1 iso_stderr_2 iso_log2_fold_change IF_overall IF1 IF2 dIF isoform_switch_q_value gene_switch_q_value PTC codingPotential
ENST00000372811 ENSG00000168389 No_inf pgKDN_inf MFSD2A protein_coding protein_coding 569.6761 170.0547 618.7603 5.370587 9.106766 1.86332 165.60779 41.71984 195.54812 1.626513 2.883421 2.228446 0.2816500 0.246425 0.316300 0.069875 0.12917199 8.976816e-05 FALSE  
ENST00000434861 ENSG00000168389 No_inf pgKDN_inf MFSD2A protein_coding protein_coding 569.6761 170.0547 618.7603 5.370587 9.106766 1.86332 70.29997 8.49943 73.59819 2.228765 6.386035 3.112732 0.1028000 0.049400 0.119325 0.069925 0.02514607 8.976816e-05 FALSE  
ENST00000469745 ENSG00000168389 No_inf pgKDN_inf MFSD2A protein_coding protein_coding_CDS_not_defined 569.6761 170.0547 618.7603 5.370587 9.106766 1.86332 119.54822 38.32597 123.07087 1.278093 8.062955 1.682836 0.2128750 0.225625 0.198500 -0.027125 0.72899006 8.976816e-05 FALSE  
ENST00000491515 ENSG00000168389 No_inf pgKDN_inf MFSD2A protein_coding protein_coding_CDS_not_defined 569.6761 170.0547 618.7603 5.370587 9.106766 1.86332 161.05567 51.64535 178.22695 4.853858 7.748361 1.786807 0.2884667 0.302575 0.287700 -0.014875 0.89386229 8.976816e-05 FALSE  
  • Note:
    • The comparisons made can be identified as “from ‘condition_1’ to ‘condition_2’”, meaning ‘condition_1’ is considered the ground state and ‘condition_2’ the changed state. This also means that a positive dIF value indicates that the isoform usage is increased in ‘condition_2’ compared to ‘condition_1’. Since the ‘isoformFeatures’ entry is the most relevant part of the switchAnalyzeRlist object, the most-used standard methods have also been implemented to work directly on isoformFeatures.

Help

Please Click HERE to learn more details about the results of IsoformSwitchAnalyzeR.

2 Differential Exon Usage

Counts

All exons whithin this gene region are shown and numbering below.

Expression

All exons whithin this gene region are shown and numbering below.

Splicing

All exons whithin this gene region are shown and numbering below.

Transcripts

All isoforms whithin this gene region are shown below.

Results

groupID featureID exonBaseMean dispersion pvalue padj seqnames start end width strand pgKDN.inf No.inf log2fold_No.inf_pgKDN.inf
ENSG00000168389 E001 0.2537694 1.632432e-02 3.075998e-02   1 39955081 39955111 31 + 0.000 0.279 11.789
ENSG00000168389 E002 1.1009895 3.343785e-01 2.402104e-01 5.294229e-01 1 39955112 39955144 33 + 0.222 0.447 1.433
ENSG00000168389 E003 1.1009895 3.343785e-01 2.402104e-01 5.294229e-01 1 39955145 39955145 1 + 0.222 0.447 1.433
ENSG00000168389 E004 1.1009895 3.343785e-01 2.402104e-01 5.294229e-01 1 39955146 39955149 4 + 0.222 0.447 1.433
ENSG00000168389 E005 6.0798747 6.054537e-03 9.091563e-03 7.553534e-02 1 39955150 39955157 8 + 0.698 1.000 1.173
ENSG00000168389 E006 161.3041891 4.770963e-04 1.498860e-07 8.385842e-06 1 39955158 39955379 222 + 2.177 2.017 -0.534
ENSG00000168389 E007 61.6450676 2.553588e-03 3.619790e-03 3.964861e-02 1 39955380 39955385 6 + 1.762 1.613 -0.504
ENSG00000168389 E008 199.2741900 9.586925e-05 2.170084e-06 9.108272e-05 1 39957087 39957221 135 + 2.261 2.139 -0.406
ENSG00000168389 E009 0.6078897 1.574181e-02 3.964338e-01 6.811489e-01 1 39957821 39957960 140 + 0.146 0.279 1.173
ENSG00000168389 E010 1.6682423 1.396293e-01 4.934006e-01 7.553525e-01 1 39958662 39958700 39 + 0.414 0.279 -0.826
ENSG00000168389 E011 230.3278735 5.523175e-04 5.561548e-05 1.456276e-03 1 39958701 39958825 125 + 2.319 2.218 -0.337
ENSG00000168389 E012 23.7476313 5.790766e-02 1.815242e-06 7.819749e-05 1 39960707 39961345 639 + 1.090 1.696 2.104
ENSG00000168389 E013 67.5971039 1.586719e-03 6.126165e-49 9.717900e-46 1 39964211 39965210 1000 + 1.537 2.132 2.010
ENSG00000168389 E014 251.5910199 8.037925e-05 1.030675e-01 3.355332e-01 1 39965211 39965334 124 + 2.343 2.310 -0.111
ENSG00000168389 E015 176.8591163 1.543232e-03 6.363118e-02 2.538751e-01 1 39965471 39965549 79 + 2.195 2.141 -0.183
ENSG00000168389 E016 257.1342179 9.706782e-05 8.421736e-01 9.433810e-01 1 39965857 39966014 158 + 2.345 2.344 -0.003
ENSG00000168389 E017 203.1915330 1.089245e-04 5.807062e-01 8.130581e-01 1 39966601 39966661 61 + 2.239 2.256 0.057
ENSG00000168389 E018 186.7193411 4.680983e-04 7.623136e-01 9.072585e-01 1 39966662 39966691 30 + 2.207 2.203 -0.016
ENSG00000168389 E019 350.5443544 4.003174e-04 1.763741e-01 4.504692e-01 1 39966811 39966932 122 + 2.484 2.460 -0.080
ENSG00000168389 E020 276.3719153 8.301078e-05 5.524366e-01 7.960223e-01 1 39967086 39967169 84 + 2.378 2.369 -0.031
ENSG00000168389 E021 9.5748217 2.534104e-03 7.597056e-09 5.514665e-07 1 39967483 39967618 136 + 0.763 1.299 1.980
ENSG00000168389 E022 4.5227182 3.471544e-03 7.651380e-04 1.222000e-02 1 39967619 39967627 9 + 0.548 0.959 1.680
ENSG00000168389 E023 261.9898812 7.575741e-05 3.750585e-01 6.626832e-01 1 39967628 39967711 84 + 2.347 2.370 0.075
ENSG00000168389 E024 14.3323774 1.994605e-03 8.894720e-10 7.675645e-08 1 39967712 39967803 92 + 0.947 1.433 1.733
ENSG00000168389 E025 309.9762171 3.454166e-04 4.651906e-01 7.343486e-01 1 39967804 39967916 113 + 2.428 2.416 -0.040
ENSG00000168389 E026 20.7500214 6.508187e-04 2.541524e-05 7.573181e-04 1 39967917 39968333 417 + 1.183 1.474 1.016
ENSG00000168389 E027 191.8687654 9.934446e-05 5.023945e-01 7.620787e-01 1 39968334 39968376 43 + 2.221 2.207 -0.046
ENSG00000168389 E028 281.4170565 6.937466e-05 1.323135e-01 3.860198e-01 1 39968377 39968477 101 + 2.375 2.409 0.115
ENSG00000168389 E029 375.8556289 9.783797e-04 9.634498e-01 9.922870e-01 1 39968569 39968745 177 + 2.508 2.512 0.014
ENSG00000168389 E030 667.6743782 4.964059e-05 7.070611e-01 8.811693e-01 1 39969505 39970981 1477 + 2.756 2.764 0.028

Help

Please Click HERE to learn more details about the results from DEXseq.