ENSG00000168488

1 Isoform Switch

Summary Plot

Only the isoforms with fraction > 5% are shown below.

  • Note:

    • About the Coding Potential: Please check the spreadsheet in the “Results” tag to confirm the coding potential. The above figure only show the predicted coding potential. The “gene_biotype” in the result spreadsheet is from the database record. Therefore, if you find conflicts between “gene_biotype” and “codingPotential”, please trust the “gene_biotype”.

    • Notes on IDR and IDR_w_binding: As the prediction of Intrinsically Disordered Regions (IDR) and Intrinsically Disordered Binding Regions (IDBR) are done by two different tools we require two things to annotate the Intrinsically Disordered Binding Regions (IDBR). Firstly the IDBR (predicted by ANCHOR2) must be a region of at least 15 amino acids (after the smoothing). Secondly the fraction of the IDBR which overlaps the IDR predictions (done by IUPred3, again after smoothing) must be at least 80%. When that is the case the IDR type will be annotated as “IDR_w_binding_region” instead of just “IDR”. The current default parameters have not been rigorously tested and should be considered experimental.

    • For the function of any other domain, please Click HERE to search it through Pfam database.

Results

isoform_id gene_id condition_1 condition_2 gene_name gene_biotype iso_biotype gene_overall_mean gene_value_1 gene_value_2 gene_stderr_1 gene_stderr_2 gene_log2_fold_change iso_overall_mean iso_value_1 iso_value_2 iso_stderr_1 iso_stderr_2 iso_log2_fold_change IF_overall IF1 IF2 dIF isoform_switch_q_value gene_switch_q_value PTC codingPotential
ENST00000336783 ENSG00000168488 No_inf pgKDN_inf ATXN2L protein_coding protein_coding 67.54451 59.44191 69.01088 3.340869 2.228567 0.2153096 5.345812 3.665321 5.374671 1.2879663 3.3083261 0.55098808 0.07939167 0.062275 0.082425 0.020150 0.85945799 0.01247224 FALSE TRUE
ENST00000382686 ENSG00000168488 No_inf pgKDN_inf ATXN2L protein_coding protein_coding 67.54451 59.44191 69.01088 3.340869 2.228567 0.2153096 4.348497 3.136211 5.255276 1.6597459 0.6094655 0.74289387 0.06292500 0.049600 0.077150 0.027550 0.71147559 0.01247224 FALSE TRUE
MSTRG.10924.12 ENSG00000168488 No_inf pgKDN_inf ATXN2L protein_coding   67.54451 59.44191 69.01088 3.340869 2.228567 0.2153096 8.204123 14.985458 2.730468 3.5312630 2.7304679 -2.45203145 0.13060000 0.264175 0.037000 -0.227175 0.01247224 0.01247224 FALSE TRUE
MSTRG.10924.13 ENSG00000168488 No_inf pgKDN_inf ATXN2L protein_coding   67.54451 59.44191 69.01088 3.340869 2.228567 0.2153096 7.361800 0.000000 8.411713 0.0000000 4.8565657 9.71796992 0.10176667 0.000000 0.117675 0.117675 0.76140174 0.01247224 FALSE TRUE
MSTRG.10924.17 ENSG00000168488 No_inf pgKDN_inf ATXN2L protein_coding   67.54451 59.44191 69.01088 3.340869 2.228567 0.2153096 4.078190 5.956729 6.277840 0.4313118 4.0403601 0.07562426 0.06593333 0.101425 0.096375 -0.005050 0.71908598 0.01247224 FALSE TRUE
MSTRG.10924.24 ENSG00000168488 No_inf pgKDN_inf ATXN2L protein_coding   67.54451 59.44191 69.01088 3.340869 2.228567 0.2153096 8.627578 7.522412 6.545831 1.5445404 1.8605610 -0.20033318 0.12494167 0.123025 0.093825 -0.029200 0.83685091 0.01247224 TRUE TRUE
  • Note:
    • The comparisons made can be identified as “from ‘condition_1’ to ‘condition_2’”, meaning ‘condition_1’ is considered the ground state and ‘condition_2’ the changed state. This also means that a positive dIF value indicates that the isoform usage is increased in ‘condition_2’ compared to ‘condition_1’. Since the ‘isoformFeatures’ entry is the most relevant part of the switchAnalyzeRlist object, the most-used standard methods have also been implemented to work directly on isoformFeatures.

Help

Please Click HERE to learn more details about the results of IsoformSwitchAnalyzeR.

2 Differential Exon Usage

Counts

All exons whithin this gene region are shown and numbering below.

Expression

All exons whithin this gene region are shown and numbering below.

Splicing

All exons whithin this gene region are shown and numbering below.

Transcripts

All isoforms whithin this gene region are shown below.

Results

groupID featureID exonBaseMean dispersion pvalue padj seqnames start end width strand pgKDN.inf No.inf log2fold_No.inf_pgKDN.inf
ENSG00000168488 E001 0.0000000       16 28822999 28823005 7 +      
ENSG00000168488 E002 0.0000000       16 28823006 28823018 13 +      
ENSG00000168488 E003 0.0000000       16 28823019 28823034 16 +      
ENSG00000168488 E004 0.0000000       16 28823035 28823047 13 +      
ENSG00000168488 E005 0.0000000       16 28823048 28823077 30 +      
ENSG00000168488 E006 0.0000000       16 28823078 28823092 15 +      
ENSG00000168488 E007 0.0000000       16 28823093 28823094 2 +      
ENSG00000168488 E008 0.0000000       16 28823095 28823251 157 +      
ENSG00000168488 E009 0.0000000       16 28823252 28823481 230 +      
ENSG00000168488 E010 0.0000000       16 28823482 28823558 77 +      
ENSG00000168488 E011 1.9263031 0.0570879398 8.582963e-02 0.3033310430 16 28824138 28824450 313 + 0.581 0.306 -1.461
ENSG00000168488 E012 1.0972129 0.0114271486 8.275991e-01 0.9375874930 16 28824451 28824542 92 + 0.337 0.306 -0.198
ENSG00000168488 E013 0.1186381 0.0117735530 5.798003e-01   16 28824543 28824661 119 + 0.091 0.000 -10.378
ENSG00000168488 E014 0.9886448 0.1663077264 4.974639e-01 0.7580752005 16 28825366 28825370 5 + 0.231 0.358 0.862
ENSG00000168488 E015 6.0812055 0.0043020192 2.607479e-01 0.5532980377 16 28825371 28825402 32 + 0.905 0.786 -0.461
ENSG00000168488 E016 12.1871704 0.0012430571 3.113949e-01 0.6045851582 16 28825624 28825680 57 + 1.157 1.079 -0.282
ENSG00000168488 E017 0.2457744 0.0164179630 9.525513e-01   16 28825681 28825769 89 + 0.091 0.099 0.124
ENSG00000168488 E018 22.2764333 0.0017361930 1.500265e-01 0.4124820565 16 28825770 28825841 72 + 1.409 1.321 -0.305
ENSG00000168488 E019 0.7532522 0.0145962948 7.732761e-02 0.2844487229 16 28825842 28826184 343 + 0.091 0.357 2.446
ENSG00000168488 E020 46.3254342 0.0004986475 1.070447e-01 0.3428888749 16 28826240 28826390 151 + 1.707 1.640 -0.227
ENSG00000168488 E021 0.3795211 0.5820332939 2.834329e-01   16 28826391 28826605 215 + 0.000 0.247 12.103
ENSG00000168488 E022 28.9568671 0.0004837637 2.342425e-02 0.1398454390 16 28826862 28826923 62 + 1.532 1.411 -0.415
ENSG00000168488 E023 32.7409972 0.0005301433 2.524619e-02 0.1462072179 16 28826924 28826986 63 + 1.580 1.468 -0.385
ENSG00000168488 E024 39.7851247 0.0030119521 2.720854e-01 0.5659022973 16 28829401 28829492 92 + 1.636 1.583 -0.178
ENSG00000168488 E025 1.4876853 0.0205908722 2.080888e-01 0.4918081893 16 28829778 28829857 80 + 0.287 0.483 1.124
ENSG00000168488 E026 17.6349862 0.0165578671 8.325033e-01 0.9395909582 16 28829858 28829868 11 + 1.258 1.282 0.084
ENSG00000168488 E027 43.7391499 0.0003381660 5.823251e-01 0.8139126271 16 28829869 28830058 190 + 1.661 1.640 -0.070
ENSG00000168488 E028 43.9368280 0.0087431512 5.830798e-01 0.8143311557 16 28830615 28830790 176 + 1.667 1.638 -0.100
ENSG00000168488 E029 0.4992614 0.0152558170 2.840865e-01   16 28830791 28830961 171 + 0.091 0.247 1.709
ENSG00000168488 E030 23.6852333 0.0009314721 1.715176e-02 0.1145163368 16 28830962 28830984 23 + 1.457 1.315 -0.492
ENSG00000168488 E031 43.5612446 0.0009213050 1.646244e-02 0.1116204259 16 28830985 28831072 88 + 1.699 1.592 -0.364
ENSG00000168488 E032 1.8228932 0.0075159185 5.336882e-01 0.7841074618 16 28832187 28832204 18 + 0.493 0.404 -0.461
ENSG00000168488 E033 76.0157348 0.0009172923 5.192388e-01 0.7739932615 16 28832205 28832399 195 + 1.873 1.900 0.092
ENSG00000168488 E034 37.5131355 0.0007238850 2.235731e-01 0.5111674726 16 28832496 28832567 72 + 1.553 1.617 0.219
ENSG00000168488 E035 41.8939481 0.0014768585 3.265012e-01 0.6189439649 16 28832817 28832887 71 + 1.606 1.658 0.175
ENSG00000168488 E036 65.7393184 0.0005474727 5.660331e-01 0.8045555646 16 28833059 28833195 137 + 1.811 1.837 0.087
ENSG00000168488 E037 75.7660211 0.0004138913 6.741470e-01 0.8649687546 16 28833196 28833354 159 + 1.876 1.894 0.064
ENSG00000168488 E038 51.8431955 0.0002968673 8.495686e-01 0.9464823086 16 28833439 28833508 70 + 1.725 1.721 -0.012
ENSG00000168488 E039 1.7318802 0.3876032710 4.593750e-01 0.7310474679 16 28833856 28834064 209 + 0.337 0.519 0.975
ENSG00000168488 E040 77.4096876 0.0002005788 2.618876e-01 0.5546345496 16 28834065 28834211 147 + 1.911 1.877 -0.113
ENSG00000168488 E041 0.4811992 0.0152837151 3.572890e-01   16 28834329 28834342 14 + 0.231 0.099 -1.461
ENSG00000168488 E042 46.5970513 0.0002983348 1.580921e-01 0.4249035205 16 28834343 28834415 73 + 1.705 1.648 -0.194
ENSG00000168488 E043 30.9037941 0.0004598539 5.570212e-01 0.7991695113 16 28834506 28834522 17 + 1.517 1.490 -0.093
ENSG00000168488 E044 83.3578560 0.0005664688 7.624605e-01 0.9073018056 16 28834523 28834693 171 + 1.929 1.923 -0.020
ENSG00000168488 E045 1.6057900 0.0082493263 3.372655e-01 0.6290798748 16 28834852 28835057 206 + 0.337 0.483 0.802
ENSG00000168488 E046 35.6636196 0.0008109291 4.569637e-01 0.7290818356 16 28835058 28835098 41 + 1.580 1.547 -0.113
ENSG00000168488 E047 58.7319742 0.0004385110 8.490274e-01 0.9464293487 16 28835099 28835187 89 + 1.770 1.782 0.040
ENSG00000168488 E048 1.1154934 0.0110475743 2.676950e-01 0.5611513402 16 28835188 28835277 90 + 0.231 0.404 1.124
ENSG00000168488 E049 62.2023069 0.0016438013 6.262856e-01 0.8393869879 16 28835278 28835399 122 + 1.808 1.793 -0.052
ENSG00000168488 E050 0.9961636 0.0115673233 1.246901e-01 0.3743682504 16 28835400 28835545 146 + 0.167 0.404 1.709
ENSG00000168488 E051 4.2724716 0.0105877334 7.848300e-01 0.9170065585 16 28835546 28835548 3 + 0.737 0.707 -0.124
ENSG00000168488 E052 17.1407128 0.0045149715 4.197200e-02 0.1993557097 16 28835549 28835554 6 + 1.326 1.178 -0.521
ENSG00000168488 E053 28.4122830 0.0084335559 2.279308e-01 0.5164132460 16 28835555 28835594 40 + 1.505 1.428 -0.262
ENSG00000168488 E054 40.2499031 0.0140078453 9.317494e-01 0.9800944147 16 28835595 28835668 74 + 1.616 1.614 -0.008
ENSG00000168488 E055 43.6847847 0.0051470216 3.114457e-01 0.6046050804 16 28835669 28835758 90 + 1.674 1.625 -0.167
ENSG00000168488 E056 63.2385409 0.0017790067 4.101753e-01 0.6921467096 16 28835933 28836122 190 + 1.822 1.793 -0.099
ENSG00000168488 E057 14.0817083 0.0058427086 2.556876e-03 0.0306178003 16 28836123 28836176 54 + 1.035 1.288 0.902
ENSG00000168488 E058 26.9460190 0.0005208362 7.207925e-06 0.0002574518 16 28836177 28836325 149 + 1.296 1.559 0.911
ENSG00000168488 E059 34.5130661 0.0082594371 6.599435e-02 0.2587481249 16 28836326 28836445 120 + 1.488 1.606 0.403
ENSG00000168488 E060 12.5747872 0.0014629636 1.944026e-02 0.1246571297 16 28836446 28836448 3 + 1.026 1.220 0.697
ENSG00000168488 E061 17.6849321 0.0130087133 2.332481e-01 0.5220785807 16 28836449 28836485 37 + 1.217 1.321 0.365
ENSG00000168488 E062 8.7600319 0.0388352761 1.176247e-01 0.3622941999 16 28836486 28836490 5 + 0.879 1.079 0.743
ENSG00000168488 E063 45.9758509 0.0231455796 1.514134e-03 0.0206533359 16 28836491 28836727 237 + 1.532 1.778 0.836
ENSG00000168488 E064 25.9339028 0.0010189669 4.955449e-02 0.2196115098 16 28836728 28836747 20 + 1.367 1.486 0.412
ENSG00000168488 E065 18.7727456 0.0107834223 3.124033e-01 0.6058233107 16 28836748 28836750 3 + 1.252 1.336 0.295
ENSG00000168488 E066 46.7292234 0.0006788517 8.157203e-01 0.9326124060 16 28836751 28836849 99 + 1.672 1.686 0.049
ENSG00000168488 E067 27.1816966 0.0051080896 6.946468e-01 0.8752493096 16 28836850 28837237 388 + 1.436 1.464 0.098

Help

Please Click HERE to learn more details about the results from DEXseq.