ENSG00000168615

1 Isoform Switch

Summary Plot

Only the isoforms with fraction > 5% are shown below.

  • Note:

    • About the Coding Potential: Please check the spreadsheet in the “Results” tag to confirm the coding potential. The above figure only show the predicted coding potential. The “gene_biotype” in the result spreadsheet is from the database record. Therefore, if you find conflicts between “gene_biotype” and “codingPotential”, please trust the “gene_biotype”.

    • Notes on IDR and IDR_w_binding: As the prediction of Intrinsically Disordered Regions (IDR) and Intrinsically Disordered Binding Regions (IDBR) are done by two different tools we require two things to annotate the Intrinsically Disordered Binding Regions (IDBR). Firstly the IDBR (predicted by ANCHOR2) must be a region of at least 15 amino acids (after the smoothing). Secondly the fraction of the IDBR which overlaps the IDR predictions (done by IUPred3, again after smoothing) must be at least 80%. When that is the case the IDR type will be annotated as “IDR_w_binding_region” instead of just “IDR”. The current default parameters have not been rigorously tested and should be considered experimental.

    • For the function of any other domain, please Click HERE to search it through Pfam database.

Results

isoform_id gene_id condition_1 condition_2 gene_name gene_biotype iso_biotype gene_overall_mean gene_value_1 gene_value_2 gene_stderr_1 gene_stderr_2 gene_log2_fold_change iso_overall_mean iso_value_1 iso_value_2 iso_stderr_1 iso_stderr_2 iso_log2_fold_change IF_overall IF1 IF2 dIF isoform_switch_q_value gene_switch_q_value PTC codingPotential
ENST00000487273 ENSG00000168615 No_inf pgKDN_inf ADAM9 protein_coding protein_coding 171.2728 107.4686 233.5862 0.7773883 1.83731 1.119967 122.57027 57.95398 169.98032 0.3497326 4.302696 1.5522239 0.6920917 0.539300 0.727775 0.188475 9.504808e-07 9.504808e-07 FALSE TRUE
ENST00000678863 ENSG00000168615 No_inf pgKDN_inf ADAM9 protein_coding nonsense_mediated_decay 171.2728 107.4686 233.5862 0.7773883 1.83731 1.119967 38.91116 41.11661 50.23188 0.2992714 2.813607 0.2888182 0.2481500 0.382625 0.215000 -0.167625 4.259750e-05 9.504808e-07 TRUE TRUE
  • Note:
    • The comparisons made can be identified as “from ‘condition_1’ to ‘condition_2’”, meaning ‘condition_1’ is considered the ground state and ‘condition_2’ the changed state. This also means that a positive dIF value indicates that the isoform usage is increased in ‘condition_2’ compared to ‘condition_1’. Since the ‘isoformFeatures’ entry is the most relevant part of the switchAnalyzeRlist object, the most-used standard methods have also been implemented to work directly on isoformFeatures.

Help

Please Click HERE to learn more details about the results of IsoformSwitchAnalyzeR.

2 Differential Exon Usage

Counts

All exons whithin this gene region are shown and numbering below.

Expression

All exons whithin this gene region are shown and numbering below.

Splicing

All exons whithin this gene region are shown and numbering below.

Transcripts

All isoforms whithin this gene region are shown below.

Results

groupID featureID exonBaseMean dispersion pvalue padj seqnames start end width strand pgKDN.inf No.inf log2fold_No.inf_pgKDN.inf
ENSG00000168615 E001 0.0000000       8 38996754 38996765 12 +      
ENSG00000168615 E002 1.3214940 2.340470e-02 7.016738e-01 8.785828e-01 8 38996766 38996868 103 + 0.374 0.312 -0.375
ENSG00000168615 E003 2.5099019 9.942354e-02 2.672356e-01 5.604226e-01 8 38996869 38996913 45 + 0.591 0.381 -1.047
ENSG00000168615 E004 3.5971696 1.481161e-01 4.853851e-01 7.492421e-01 8 38996914 38996942 29 + 0.692 0.539 -0.675
ENSG00000168615 E005 4.3384917 1.244122e-02 5.388255e-01 7.873694e-01 8 38996943 38996972 30 + 0.735 0.654 -0.338
ENSG00000168615 E006 3.3873600 6.896482e-03 9.459934e-01 9.855131e-01 8 38996973 38996974 2 + 0.628 0.619 -0.038
ENSG00000168615 E007 7.5716797 5.245057e-03 1.319657e-01 3.854348e-01 8 38996975 38996985 11 + 0.963 0.797 -0.638
ENSG00000168615 E008 30.4214141 4.438521e-04 6.867705e-03 6.227740e-02 8 38996986 38997025 40 + 1.524 1.364 -0.552
ENSG00000168615 E009 75.4535197 1.839674e-04 3.017487e-06 1.214516e-04 8 38997026 38997160 135 + 1.915 1.735 -0.607
ENSG00000168615 E010 1.3558909 4.762720e-02 1.599410e-01 4.275271e-01 8 39006609 39007885 1277 + 0.268 0.492 1.303
ENSG00000168615 E011 77.2020402 2.680284e-04 4.067412e-03 4.292991e-02 8 39007886 39007983 98 + 1.905 1.798 -0.361
ENSG00000168615 E012 61.4305438 1.686823e-03 2.287503e-01 5.174874e-01 8 39011658 39011716 59 + 1.791 1.738 -0.178
ENSG00000168615 E013 62.2835170 5.811443e-03 7.199476e-02 2.720803e-01 8 39013965 39014043 79 + 1.809 1.715 -0.319
ENSG00000168615 E014 0.1272623 1.239605e-02 2.470333e-01   8 39014044 39014491 448 + 0.000 0.131 11.488
ENSG00000168615 E015 2.4564390 2.168114e-02 5.258243e-02 2.279222e-01 8 39014492 39016117 1626 + 0.404 0.687 1.330
ENSG00000168615 E016 64.0197495 1.466550e-03 8.334802e-02 2.975220e-01 8 39016118 39016194 77 + 1.815 1.741 -0.251
ENSG00000168615 E017 4.7329023 3.471406e-03 3.678422e-07 1.878712e-05 8 39016195 39017218 1024 + 0.432 1.035 2.526
ENSG00000168615 E018 118.4996108 1.339520e-04 6.063258e-03 5.694547e-02 8 39017219 39017414 196 + 2.082 2.000 -0.273
ENSG00000168615 E019 54.3535142 2.571233e-04 4.657554e-02 2.117870e-01 8 39018853 39018881 29 + 1.749 1.662 -0.295
ENSG00000168615 E020 55.0308080 2.647885e-04 2.573505e-01 5.495654e-01 8 39018882 39018918 37 + 1.743 1.694 -0.164
ENSG00000168615 E021 2.2578979 6.545300e-03 1.226866e-05 4.074493e-04 8 39018919 39021642 2724 + 0.180 0.797 3.362
ENSG00000168615 E022 65.3822364 2.171357e-04 4.338914e-03 4.489927e-02 8 39021643 39021714 72 + 1.836 1.721 -0.389
ENSG00000168615 E023 136.5018249 1.250925e-04 7.523634e-03 6.631456e-02 8 39023156 39023325 170 + 2.140 2.066 -0.247
ENSG00000168615 E024 106.5777198 1.547715e-04 4.785060e-01 7.444887e-01 8 39025803 39025884 82 + 2.017 1.995 -0.072
ENSG00000168615 E025 147.4064173 2.475600e-03 1.465972e-01 4.076740e-01 8 39026677 39026810 134 + 2.165 2.117 -0.162
ENSG00000168615 E026 0.0000000       8 39032718 39032836 119 +      
ENSG00000168615 E027 185.3652197 9.375210e-05 9.032562e-05 2.186545e-03 8 39041946 39042117 172 + 2.278 2.185 -0.311
ENSG00000168615 E028 0.1265070 1.233358e-02 2.470403e-01   8 39046002 39046058 57 + 0.000 0.131 11.489
ENSG00000168615 E029 0.0000000       8 39046954 39047046 93 +      
ENSG00000168615 E030 124.3717364 2.339084e-04 1.788742e-03 2.342739e-02 8 39054481 39054573 93 + 2.105 2.013 -0.308
ENSG00000168615 E031 184.9026847 1.061217e-04 1.797664e-01 4.550178e-01 8 39055577 39055772 196 + 2.257 2.226 -0.104
ENSG00000168615 E032 114.8873557 1.483549e-04 4.272316e-01 7.057152e-01 8 39071298 39071403 106 + 2.050 2.027 -0.077
ENSG00000168615 E033 0.3638483 1.675259e-02 1.000000e+00   8 39071404 39071413 10 + 0.128 0.131 0.040
ENSG00000168615 E034 6.7837221 3.686305e-02 1.355823e-03 1.895411e-02 8 39072937 39076146 3210 + 0.693 1.088 1.516
ENSG00000168615 E035 4.7114984 3.046481e-03 4.041988e-05 1.110469e-03 8 39076147 39076275 129 + 0.508 0.990 1.984
ENSG00000168615 E036 179.4472194 9.879709e-05 4.610538e-01 7.320564e-01 8 39077228 39077411 184 + 2.228 2.246 0.061
ENSG00000168615 E037 114.2863202 8.508848e-04 8.224887e-01 9.355712e-01 8 39082641 39082721 81 + 2.037 2.045 0.027
ENSG00000168615 E038 172.5469918 1.118745e-04 8.485587e-01 9.463687e-01 8 39082968 39083073 106 + 2.218 2.214 -0.013
ENSG00000168615 E039 171.1309429 2.665053e-04 1.305479e-01 3.832730e-01 8 39090047 39090135 89 + 2.226 2.189 -0.125
ENSG00000168615 E040 150.8560007 1.167253e-04 7.282687e-01 8.916594e-01 8 39090136 39090188 53 + 2.162 2.154 -0.028
ENSG00000168615 E041 10.4896357 1.328000e-03 7.606297e-16 1.395367e-13 8 39090189 39091242 1054 + 0.645 1.370 2.718
ENSG00000168615 E042 0.7453831 4.750176e-01 3.908089e-01 6.761266e-01 8 39091243 39091258 16 + 0.128 0.381 2.041
ENSG00000168615 E043 99.6980301 1.870587e-03 6.441739e-01 8.492705e-01 8 39091259 39091263 5 + 1.975 1.992 0.059
ENSG00000168615 E044 189.2874510 1.604150e-03 1.582889e-01 4.251911e-01 8 39091264 39091346 83 + 2.243 2.283 0.135
ENSG00000168615 E045 0.9613264 1.171629e-02 6.355584e-01 8.445196e-01 8 39091672 39091764 93 + 0.306 0.231 -0.545
ENSG00000168615 E046 2.3030824 6.355101e-03 7.108697e-01 8.831060e-01 8 39100456 39101862 1407 + 0.484 0.539 0.263
ENSG00000168615 E047 160.1358011 4.386681e-04 1.813586e-02 1.188938e-01 8 39101863 39101930 68 + 2.163 2.225 0.208
ENSG00000168615 E048 1630.1895329 2.315570e-05 1.947021e-15 3.420541e-13 8 39103607 39105445 1839 + 3.172 3.223 0.172

Help

Please Click HERE to learn more details about the results from DEXseq.