ENSG00000168734

1 Isoform Switch

Summary Plot

Only the isoforms with fraction > 5% are shown below.

  • Note:

    • About the Coding Potential: Please check the spreadsheet in the “Results” tag to confirm the coding potential. The above figure only show the predicted coding potential. The “gene_biotype” in the result spreadsheet is from the database record. Therefore, if you find conflicts between “gene_biotype” and “codingPotential”, please trust the “gene_biotype”.

    • Notes on IDR and IDR_w_binding: As the prediction of Intrinsically Disordered Regions (IDR) and Intrinsically Disordered Binding Regions (IDBR) are done by two different tools we require two things to annotate the Intrinsically Disordered Binding Regions (IDBR). Firstly the IDBR (predicted by ANCHOR2) must be a region of at least 15 amino acids (after the smoothing). Secondly the fraction of the IDBR which overlaps the IDR predictions (done by IUPred3, again after smoothing) must be at least 80%. When that is the case the IDR type will be annotated as “IDR_w_binding_region” instead of just “IDR”. The current default parameters have not been rigorously tested and should be considered experimental.

    • For the function of any other domain, please Click HERE to search it through Pfam database.

Results

isoform_id gene_id condition_1 condition_2 gene_name gene_biotype iso_biotype gene_overall_mean gene_value_1 gene_value_2 gene_stderr_1 gene_stderr_2 gene_log2_fold_change iso_overall_mean iso_value_1 iso_value_2 iso_stderr_1 iso_stderr_2 iso_log2_fold_change IF_overall IF1 IF2 dIF isoform_switch_q_value gene_switch_q_value PTC codingPotential
ENST00000372886 ENSG00000168734 No_inf pgKDN_inf PKIG protein_coding protein_coding 10.17306 4.047208 12.7484 0.5789241 1.565669 1.652889 6.7422692 0.8538451 7.899748 0.8538451 0.2299847 3.194787 0.57502500 0.250000 0.646950 0.396950 0.18882402 0.04414447   FALSE
ENST00000372891 ENSG00000168734 No_inf pgKDN_inf PKIG protein_coding protein_coding 10.17306 4.047208 12.7484 0.5789241 1.565669 1.652889 0.4676659 0.0000000 1.213867 0.0000000 0.4449585 6.935303 0.03772500 0.000000 0.099825 0.099825 0.17510353 0.04414447 TRUE FALSE
ENST00000372892 ENSG00000168734 No_inf pgKDN_inf PKIG protein_coding protein_coding 10.17306 4.047208 12.7484 0.5789241 1.565669 1.652889 0.8778448 0.0000000 1.810275 0.0000000 1.0594068 7.508012 0.06545833 0.000000 0.131925 0.131925 0.69984230 0.04414447 TRUE FALSE
ENST00000372894 ENSG00000168734 No_inf pgKDN_inf PKIG protein_coding protein_coding 10.17306 4.047208 12.7484 0.5789241 1.565669 1.652889 1.1689194 2.6744283 0.000000 0.8957816 0.0000000 -8.068471 0.24098333 0.660025 0.000000 -0.660025 0.04414447 0.04414447   FALSE
ENST00000477390 ENSG00000168734 No_inf pgKDN_inf PKIG protein_coding protein_coding_CDS_not_defined 10.17306 4.047208 12.7484 0.5789241 1.565669 1.652889 0.3516936 0.0000000 1.055081 0.0000000 1.0550809 6.734819 0.02074167 0.000000 0.062225 0.062225 1.00000000 0.04414447   FALSE
  • Note:
    • The comparisons made can be identified as “from ‘condition_1’ to ‘condition_2’”, meaning ‘condition_1’ is considered the ground state and ‘condition_2’ the changed state. This also means that a positive dIF value indicates that the isoform usage is increased in ‘condition_2’ compared to ‘condition_1’. Since the ‘isoformFeatures’ entry is the most relevant part of the switchAnalyzeRlist object, the most-used standard methods have also been implemented to work directly on isoformFeatures.

Help

Please Click HERE to learn more details about the results of IsoformSwitchAnalyzeR.

2 Differential Exon Usage

Counts

All exons whithin this gene region are shown and numbering below.

Expression

All exons whithin this gene region are shown and numbering below.

Splicing

All exons whithin this gene region are shown and numbering below.

Transcripts

All isoforms whithin this gene region are shown below.

Results

groupID featureID exonBaseMean dispersion pvalue padj seqnames start end width strand pgKDN.inf No.inf log2fold_No.inf_pgKDN.inf
ENSG00000168734 E001 0.6064191 0.019074021 0.5285311373 0.78020471 20 44531785 44531908 124 + 0.161 0.255 0.829
ENSG00000168734 E002 0.6064191 0.019074021 0.5285311373 0.78020471 20 44531909 44531915 7 + 0.161 0.255 0.829
ENSG00000168734 E003 1.2415671 0.012227881 0.0045528244 0.04639184 20 44531916 44531926 11 + 0.161 0.579 2.637
ENSG00000168734 E004 1.3688294 0.012117994 0.0015536978 0.02101232 20 44531927 44531978 52 + 0.161 0.623 2.829
ENSG00000168734 E005 0.0000000       20 44564201 44564340 140 +      
ENSG00000168734 E006 0.2346346 0.016294412 1.0000000000   20 44582579 44582584 6 + 0.114 0.000 -9.820
ENSG00000168734 E007 4.0291943 0.003927481 0.0009005499 0.01383374 20 44582585 44582731 147 + 0.763 0.255 -2.586
ENSG00000168734 E008 0.0000000       20 44585100 44585204 105 +      
ENSG00000168734 E009 4.0878302 0.004014631 0.9384784494 0.98223255 20 44589797 44589866 70 + 0.677 0.662 -0.060
ENSG00000168734 E010 0.6088699 0.016737644 0.5306317532 0.78163231 20 44598616 44598890 275 + 0.161 0.255 0.829
ENSG00000168734 E011 0.1176306 0.012612101 1.0000000000   20 44614308 44614533 226 + 0.061 0.000 -8.990
ENSG00000168734 E012 8.4581192 0.001872769 0.0010330127 0.01536104 20 44614534 44614707 174 + 1.013 0.662 -1.370
ENSG00000168734 E013 0.1170040 0.012066314 1.0000000000   20 44614708 44614768 61 + 0.061 0.000 -8.990
ENSG00000168734 E014 13.6737037 0.001477494 0.0477474994 0.21488765 20 44618285 44619037 753 + 1.088 1.209 0.433
ENSG00000168734 E015 0.0000000       20 44623933 44624247 315 +      

Help

Please Click HERE to learn more details about the results from DEXseq.