ENSG00000168758

1 Isoform Switch

Summary Plot

Only the isoforms with fraction > 5% are shown below.

  • Note:

    • About the Coding Potential: Please check the spreadsheet in the “Results” tag to confirm the coding potential. The above figure only show the predicted coding potential. The “gene_biotype” in the result spreadsheet is from the database record. Therefore, if you find conflicts between “gene_biotype” and “codingPotential”, please trust the “gene_biotype”.

    • Notes on IDR and IDR_w_binding: As the prediction of Intrinsically Disordered Regions (IDR) and Intrinsically Disordered Binding Regions (IDBR) are done by two different tools we require two things to annotate the Intrinsically Disordered Binding Regions (IDBR). Firstly the IDBR (predicted by ANCHOR2) must be a region of at least 15 amino acids (after the smoothing). Secondly the fraction of the IDBR which overlaps the IDR predictions (done by IUPred3, again after smoothing) must be at least 80%. When that is the case the IDR type will be annotated as “IDR_w_binding_region” instead of just “IDR”. The current default parameters have not been rigorously tested and should be considered experimental.

    • For the function of any other domain, please Click HERE to search it through Pfam database.

Results

isoform_id gene_id condition_1 condition_2 gene_name gene_biotype iso_biotype gene_overall_mean gene_value_1 gene_value_2 gene_stderr_1 gene_stderr_2 gene_log2_fold_change iso_overall_mean iso_value_1 iso_value_2 iso_stderr_1 iso_stderr_2 iso_log2_fold_change IF_overall IF1 IF2 dIF isoform_switch_q_value gene_switch_q_value PTC codingPotential
ENST00000474420 ENSG00000168758 No_inf pgKDN_inf SEMA4C protein_coding retained_intron 30.98613 32.60965 31.98301 0.6938358 0.1828728 -0.02798459 1.775197 3.848595 0.00000 1.3232625 0.000000 -8.5919318 0.05654167 0.117475 0.000000 -0.117475 0.02394056 0.02394056 FALSE TRUE
MSTRG.16710.10 ENSG00000168758 No_inf pgKDN_inf SEMA4C protein_coding   30.98613 32.60965 31.98301 0.6938358 0.1828728 -0.02798459 22.010126 20.980058 23.77366 0.8319835 1.403929 0.1802647 0.71236667 0.643075 0.743625 0.100550 0.52893799 0.02394056 FALSE TRUE
  • Note:
    • The comparisons made can be identified as “from ‘condition_1’ to ‘condition_2’”, meaning ‘condition_1’ is considered the ground state and ‘condition_2’ the changed state. This also means that a positive dIF value indicates that the isoform usage is increased in ‘condition_2’ compared to ‘condition_1’. Since the ‘isoformFeatures’ entry is the most relevant part of the switchAnalyzeRlist object, the most-used standard methods have also been implemented to work directly on isoformFeatures.

Help

Please Click HERE to learn more details about the results of IsoformSwitchAnalyzeR.

2 Differential Exon Usage

Counts

All exons whithin this gene region are shown and numbering below.

Expression

All exons whithin this gene region are shown and numbering below.

Splicing

All exons whithin this gene region are shown and numbering below.

Transcripts

All isoforms whithin this gene region are shown below.

Results

groupID featureID exonBaseMean dispersion pvalue padj seqnames start end width strand pgKDN.inf No.inf log2fold_No.inf_pgKDN.inf
ENSG00000168758 E001 0.0000000       2 96859718 96859735 18 -      
ENSG00000168758 E002 0.1272623 0.0123328607 6.262057e-01   2 96859736 96859741 6 - 0.000 0.089 8.613
ENSG00000168758 E003 0.3730368 0.0165650101 6.829429e-01   2 96859742 96859747 6 - 0.102 0.162 0.778
ENSG00000168758 E004 2.8210390 0.0050720109 8.741378e-01 9.569878e-01 2 96859748 96860028 281 - 0.592 0.570 -0.097
ENSG00000168758 E005 0.1176306 0.0117275533 4.611321e-01   2 96860029 96860035 7 - 0.102 0.000 -11.717
ENSG00000168758 E006 0.2362687 0.0156849896 1.940710e-01   2 96860036 96860044 9 - 0.184 0.000 -12.651
ENSG00000168758 E007 4.4398853 0.0034729161 3.842404e-01 6.703419e-01 2 96860045 96860068 24 - 0.672 0.777 0.430
ENSG00000168758 E008 273.7627164 0.0001177286 1.929245e-01 4.727265e-01 2 96860069 96861455 1387 - 2.447 2.428 -0.063
ENSG00000168758 E009 3.4915951 0.0105059765 2.510340e-02 1.457300e-01 2 96861456 96861578 123 - 0.455 0.760 1.363
ENSG00000168758 E010 25.5967164 0.0011192713 3.011120e-01 5.941404e-01 2 96861579 96861649 71 - 1.455 1.394 -0.208
ENSG00000168758 E011 38.7271094 0.0004012839 5.356672e-01 7.853253e-01 2 96861737 96861894 158 - 1.580 1.609 0.100
ENSG00000168758 E012 19.1812391 0.0009536876 1.312446e-13 1.928759e-11 2 96861895 96863328 1434 - 0.910 1.471 2.000
ENSG00000168758 E013 26.0221300 0.0006068014 9.838940e-01 9.986907e-01 2 96863682 96863794 113 - 1.430 1.429 -0.004
ENSG00000168758 E014 40.5329956 0.0003717840 1.391188e-01 3.965979e-01 2 96863926 96864148 223 - 1.652 1.584 -0.231
ENSG00000168758 E015 32.2906246 0.0004881268 1.700403e-01 4.421655e-01 2 96864238 96864382 145 - 1.478 1.550 0.244
ENSG00000168758 E016 29.9771031 0.0004593313 9.347755e-01 9.812413e-01 2 96864705 96864880 176 - 1.486 1.490 0.015
ENSG00000168758 E017 11.7261058 0.0133641127 2.276429e-01 5.160967e-01 2 96864964 96864993 30 - 1.161 1.049 -0.403
ENSG00000168758 E018 21.3529244 0.0151345631 8.348380e-01 9.405494e-01 2 96864994 96865115 122 - 1.356 1.339 -0.056
ENSG00000168758 E019 10.4314857 0.0182959581 7.296047e-01 8.922265e-01 2 96865204 96865233 30 - 1.073 1.040 -0.120
ENSG00000168758 E020 19.5087902 0.0008819534 6.795518e-01 8.676012e-01 2 96865234 96865320 87 - 1.324 1.297 -0.095
ENSG00000168758 E021 18.4976901 0.0007323202 3.873741e-01 6.733127e-01 2 96865441 96865537 97 - 1.319 1.261 -0.203
ENSG00000168758 E022 0.3726284 0.0165616960 6.831526e-01   2 96865538 96865593 56 - 0.102 0.162 0.778
ENSG00000168758 E023 7.3308067 0.0030956326 2.739441e-01 5.676327e-01 2 96865666 96865666 1 - 0.976 0.866 -0.415
ENSG00000168758 E024 21.5378073 0.0029029604 2.056158e-01 4.889818e-01 2 96865667 96865764 98 - 1.394 1.312 -0.288
ENSG00000168758 E025 16.6936613 0.0101389959 8.628542e-01 9.525989e-01 2 96865867 96865929 63 - 1.253 1.238 -0.052
ENSG00000168758 E026 23.4310015 0.0081863825 6.247984e-01 8.385803e-01 2 96866283 96866431 149 - 1.404 1.370 -0.117
ENSG00000168758 E027 4.3442918 0.0138304570 9.258770e-02 3.160922e-01 2 96866432 96866930 499 - 0.592 0.809 0.904
ENSG00000168758 E028 16.5731187 0.0135192079 7.992924e-01 9.247095e-01 2 96867778 96867923 146 - 1.253 1.233 -0.073
ENSG00000168758 E029 2.7023385 0.0053212614 9.479487e-01 9.864316e-01 2 96867924 96867926 3 - 0.562 0.570 0.041
ENSG00000168758 E030 5.4242153 0.0027868970 4.878088e-01 7.512272e-01 2 96868416 96868794 379 - 0.760 0.838 0.308
ENSG00000168758 E031 1.2625224 0.0152066943 1.458940e-02 1.031142e-01 2 96869187 96869245 59 - 0.102 0.483 2.948
ENSG00000168758 E032 4.0636981 0.0098683430 6.765840e-01 8.659598e-01 2 96869876 96870122 247 - 0.672 0.725 0.218
ENSG00000168758 E033 1.3683201 0.0240873109 2.122779e-01 4.974796e-01 2 96870378 96870757 380 - 0.254 0.449 1.193

Help

Please Click HERE to learn more details about the results from DEXseq.