ENSG00000168779

1 Isoform Switch

Summary Plot

Only the isoforms with fraction > 5% are shown below.

  • Note:

    • About the Coding Potential: Please check the spreadsheet in the “Results” tag to confirm the coding potential. The above figure only show the predicted coding potential. The “gene_biotype” in the result spreadsheet is from the database record. Therefore, if you find conflicts between “gene_biotype” and “codingPotential”, please trust the “gene_biotype”.

    • Notes on IDR and IDR_w_binding: As the prediction of Intrinsically Disordered Regions (IDR) and Intrinsically Disordered Binding Regions (IDBR) are done by two different tools we require two things to annotate the Intrinsically Disordered Binding Regions (IDBR). Firstly the IDBR (predicted by ANCHOR2) must be a region of at least 15 amino acids (after the smoothing). Secondly the fraction of the IDBR which overlaps the IDR predictions (done by IUPred3, again after smoothing) must be at least 80%. When that is the case the IDR type will be annotated as “IDR_w_binding_region” instead of just “IDR”. The current default parameters have not been rigorously tested and should be considered experimental.

    • For the function of any other domain, please Click HERE to search it through Pfam database.

Results

isoform_id gene_id condition_1 condition_2 gene_name gene_biotype iso_biotype gene_overall_mean gene_value_1 gene_value_2 gene_stderr_1 gene_stderr_2 gene_log2_fold_change iso_overall_mean iso_value_1 iso_value_2 iso_stderr_1 iso_stderr_2 iso_log2_fold_change IF_overall IF1 IF2 dIF isoform_switch_q_value gene_switch_q_value PTC codingPotential
ENST00000441443 ENSG00000168779 No_inf pgKDN_inf SHOX2 protein_coding protein_coding 47.71377 106.2374 17.45967 0.5175597 0.2620329 -2.604503 3.071731 2.594127 2.7196437 2.5941268 0.9743206 0.06791293 0.1280833 0.024600 0.157375 0.132775 0.125928451 0.000316363 FALSE  
ENST00000483851 ENSG00000168779 No_inf pgKDN_inf SHOX2 protein_coding protein_coding 47.71377 106.2374 17.45967 0.5175597 0.2620329 -2.604503 5.792748 12.812384 2.0819744 2.3220672 1.4417410 -2.61572745 0.1218250 0.120525 0.119350 -0.001175 0.801795232 0.000316363 FALSE  
MSTRG.21011.3 ENSG00000168779 No_inf pgKDN_inf SHOX2 protein_coding   47.71377 106.2374 17.45967 0.5175597 0.2620329 -2.604503 5.438002 9.047578 6.2094027 5.6925007 1.0361730 -0.54234926 0.1640167 0.085150 0.354250 0.269100 0.221359191 0.000316363 FALSE  
MSTRG.21011.4 ENSG00000168779 No_inf pgKDN_inf SHOX2 protein_coding   47.71377 106.2374 17.45967 0.5175597 0.2620329 -2.604503 13.689466 33.672562 3.3196292 0.5315935 0.6116525 -3.33856847 0.2399500 0.317000 0.190500 -0.126500 0.234786578 0.000316363 FALSE  
MSTRG.21011.5 ENSG00000168779 No_inf pgKDN_inf SHOX2 protein_coding   47.71377 106.2374 17.45967 0.5175597 0.2620329 -2.604503 3.135672 8.862585 0.0000000 2.0433864 0.0000000 -9.79321074 0.0367750 0.083650 0.000000 -0.083650 0.000316363 0.000316363 FALSE  
MSTRG.21011.6 ENSG00000168779 No_inf pgKDN_inf SHOX2 protein_coding   47.71377 106.2374 17.45967 0.5175597 0.2620329 -2.604503 5.978656 14.941097 0.3798544 5.3120934 0.3798544 -5.26117201 0.0985750 0.140475 0.021425 -0.119050 0.397094356 0.000316363 FALSE  
MSTRG.21011.7 ENSG00000168779 No_inf pgKDN_inf SHOX2 protein_coding   47.71377 106.2374 17.45967 0.5175597 0.2620329 -2.604503 3.689179 9.825221 0.7390996 0.8016686 0.2009948 -3.71472788 0.0535750 0.092375 0.042100 -0.050275 0.413802223 0.000316363 FALSE  
MSTRG.21011.9 ENSG00000168779 No_inf pgKDN_inf SHOX2 protein_coding   47.71377 106.2374 17.45967 0.5175597 0.2620329 -2.604503 5.555893 11.735563 1.6167468 2.0952797 0.7346194 -2.85205426 0.1250417 0.110350 0.092600 -0.017750 0.854045472 0.000316363 FALSE  
  • Note:
    • The comparisons made can be identified as “from ‘condition_1’ to ‘condition_2’”, meaning ‘condition_1’ is considered the ground state and ‘condition_2’ the changed state. This also means that a positive dIF value indicates that the isoform usage is increased in ‘condition_2’ compared to ‘condition_1’. Since the ‘isoformFeatures’ entry is the most relevant part of the switchAnalyzeRlist object, the most-used standard methods have also been implemented to work directly on isoformFeatures.

Help

Please Click HERE to learn more details about the results of IsoformSwitchAnalyzeR.

2 Differential Exon Usage

Counts

All exons whithin this gene region are shown and numbering below.

Expression

All exons whithin this gene region are shown and numbering below.

Splicing

All exons whithin this gene region are shown and numbering below.

Transcripts

All isoforms whithin this gene region are shown below.

Results

groupID featureID exonBaseMean dispersion pvalue padj seqnames start end width strand pgKDN.inf No.inf log2fold_No.inf_pgKDN.inf
ENSG00000168779 E001 0.0000000       3 158095905 158095953 49 -      
ENSG00000168779 E002 0.0000000       3 158095954 158095963 10 -      
ENSG00000168779 E003 0.2346346 0.0155996151 5.144532e-03   3 158095964 158095964 1 - 0.372 0.000 -12.789
ENSG00000168779 E004 1.2128866 0.1402548775 1.579293e-03 2.127312e-02 3 158095965 158095966 2 - 0.704 0.132 -3.518
ENSG00000168779 E005 4.3593896 0.0506492451 4.587211e-02 2.098468e-01 3 158095967 158096010 44 - 0.850 0.519 -1.402
ENSG00000168779 E006 355.1789514 0.0008552470 1.033221e-01 3.360184e-01 3 158096011 158096978 968 - 2.387 2.341 -0.155
ENSG00000168779 E007 101.9956815 0.0001499901 2.424158e-01 5.320888e-01 3 158096979 158097158 180 - 1.862 1.802 -0.200
ENSG00000168779 E008 478.5251378 0.0008283103 2.797154e-06 1.132596e-04 3 158097159 158098284 1126 - 2.561 2.464 -0.324
ENSG00000168779 E009 10.0404770 0.0013459519 2.366905e-01 5.256600e-01 3 158098285 158098320 36 - 0.991 0.841 -0.568
ENSG00000168779 E010 0.7525292 0.0301252876 6.956486e-01 8.757607e-01 3 158099856 158099859 4 - 0.224 0.159 -0.611
ENSG00000168779 E011 33.6728099 0.0004252996 1.676295e-01 4.383214e-01 3 158099860 158099884 25 - 1.438 1.328 -0.380
ENSG00000168779 E012 48.7089202 0.0003017882 8.154007e-01 9.325040e-01 3 158099885 158099948 64 - 1.516 1.493 -0.079
ENSG00000168779 E013 43.5809216 0.0003766045 6.460525e-01 8.502110e-01 3 158100254 158100311 58 - 1.427 1.451 0.085
ENSG00000168779 E014 96.0068091 0.0006114035 4.836022e-01 7.480598e-01 3 158102678 158102886 209 - 1.819 1.779 -0.137
ENSG00000168779 E015 89.0408802 0.0003027084 2.821740e-05 8.235267e-04 3 158102887 158103226 340 - 1.542 1.771 0.778
ENSG00000168779 E016 133.0088138 0.0008106710 4.642889e-08 2.911739e-06 3 158103227 158104000 774 - 1.690 1.944 0.856
ENSG00000168779 E017 32.3594624 0.0004321847 1.265102e-03 1.792748e-02 3 158104001 158104142 142 - 1.047 1.349 1.072
ENSG00000168779 E018 27.1735600 0.0004965977 4.420305e-03 4.548668e-02 3 158104143 158104347 205 - 0.991 1.276 1.024
ENSG00000168779 E019 23.8358185 0.0084239130 2.550591e-01 5.469942e-01 3 158104348 158104562 215 - 1.097 1.210 0.405
ENSG00000168779 E020 41.4462407 0.0003787969 2.063259e-03 2.618349e-02 3 158104563 158105057 495 - 1.201 1.449 0.864
ENSG00000168779 E021 9.9907669 0.0015042802 4.010223e-02 1.941190e-01 3 158105058 158105125 68 - 0.569 0.883 1.295
ENSG00000168779 E022 7.2082994 0.0018784853 9.216439e-02 3.153257e-01 3 158105126 158105129 4 - 0.481 0.762 1.236
ENSG00000168779 E023 15.5661413 0.0009124773 8.107737e-03 6.973093e-02 3 158105130 158105466 337 - 0.704 1.055 1.352
ENSG00000168779 E024 39.4116287 0.0003586656 8.844608e-01 9.610937e-01 3 158105679 158106552 874 - 1.404 1.407 0.010

Help

Please Click HERE to learn more details about the results from DEXseq.