ENSG00000168958

1 Isoform Switch

Summary Plot

Only the isoforms with fraction > 5% are shown below.

  • Note:

    • About the Coding Potential: Please check the spreadsheet in the “Results” tag to confirm the coding potential. The above figure only show the predicted coding potential. The “gene_biotype” in the result spreadsheet is from the database record. Therefore, if you find conflicts between “gene_biotype” and “codingPotential”, please trust the “gene_biotype”.

    • Notes on IDR and IDR_w_binding: As the prediction of Intrinsically Disordered Regions (IDR) and Intrinsically Disordered Binding Regions (IDBR) are done by two different tools we require two things to annotate the Intrinsically Disordered Binding Regions (IDBR). Firstly the IDBR (predicted by ANCHOR2) must be a region of at least 15 amino acids (after the smoothing). Secondly the fraction of the IDBR which overlaps the IDR predictions (done by IUPred3, again after smoothing) must be at least 80%. When that is the case the IDR type will be annotated as “IDR_w_binding_region” instead of just “IDR”. The current default parameters have not been rigorously tested and should be considered experimental.

    • For the function of any other domain, please Click HERE to search it through Pfam database.

Results

isoform_id gene_id condition_1 condition_2 gene_name gene_biotype iso_biotype gene_overall_mean gene_value_1 gene_value_2 gene_stderr_1 gene_stderr_2 gene_log2_fold_change iso_overall_mean iso_value_1 iso_value_2 iso_stderr_1 iso_stderr_2 iso_log2_fold_change IF_overall IF1 IF2 dIF isoform_switch_q_value gene_switch_q_value PTC codingPotential
ENST00000409565 ENSG00000168958 No_inf pgKDN_inf MFF protein_coding protein_coding 56.51551 51.61432 62.71235 3.92171 1.993146 0.2809288 4.797937 8.460100 4.190817 0.8296189 4.190817 -1.0117092 0.09016667 0.166025 0.072400 -0.093625 0.04886953 0.02171302 FALSE  
ENST00000476924 ENSG00000168958 No_inf pgKDN_inf MFF protein_coding protein_coding_CDS_not_defined 56.51551 51.61432 62.71235 3.92171 1.993146 0.2809288 3.504521 0.000000 5.680525 0.0000000 2.409906 9.1524179 0.05915833 0.000000 0.089525 0.089525 0.02171302 0.02171302 FALSE  
ENST00000534203 ENSG00000168958 No_inf pgKDN_inf MFF protein_coding protein_coding 56.51551 51.61432 62.71235 3.92171 1.993146 0.2809288 2.515147 0.000000 5.698725 0.0000000 4.576178 9.1570248 0.03980000 0.000000 0.085250 0.085250 0.50116377 0.02171302 FALSE  
MSTRG.17716.18 ENSG00000168958 No_inf pgKDN_inf MFF protein_coding   56.51551 51.61432 62.71235 3.92171 1.993146 0.2809288 3.517225 4.950471 3.127830 0.9391642 1.314218 -0.6607098 0.06400000 0.097250 0.050725 -0.046525 0.68230266 0.02171302 FALSE  
MSTRG.17716.19 ENSG00000168958 No_inf pgKDN_inf MFF protein_coding   56.51551 51.61432 62.71235 3.92171 1.993146 0.2809288 3.475498 3.252330 3.663111 0.6891192 1.322950 0.1710995 0.06274167 0.065425 0.059525 -0.005900 0.92856464 0.02171302 FALSE  
MSTRG.17716.8 ENSG00000168958 No_inf pgKDN_inf MFF protein_coding   56.51551 51.61432 62.71235 3.92171 1.993146 0.2809288 18.283850 12.466575 21.109481 1.0513385 1.833632 0.7593524 0.32159167 0.241275 0.338825 0.097550 0.46964779 0.02171302 FALSE  
  • Note:
    • The comparisons made can be identified as “from ‘condition_1’ to ‘condition_2’”, meaning ‘condition_1’ is considered the ground state and ‘condition_2’ the changed state. This also means that a positive dIF value indicates that the isoform usage is increased in ‘condition_2’ compared to ‘condition_1’. Since the ‘isoformFeatures’ entry is the most relevant part of the switchAnalyzeRlist object, the most-used standard methods have also been implemented to work directly on isoformFeatures.

Help

Please Click HERE to learn more details about the results of IsoformSwitchAnalyzeR.

2 Differential Exon Usage

Counts

All exons whithin this gene region are shown and numbering below.

Expression

All exons whithin this gene region are shown and numbering below.

Splicing

All exons whithin this gene region are shown and numbering below.

Transcripts

All isoforms whithin this gene region are shown below.

Results

groupID featureID exonBaseMean dispersion pvalue padj seqnames start end width strand pgKDN.inf No.inf log2fold_No.inf_pgKDN.inf
ENSG00000168958 E001 0.0000000       2 227325151 227325220 70 +      
ENSG00000168958 E002 0.0000000       2 227325221 227325233 13 +      
ENSG00000168958 E003 0.0000000       2 227325234 227325238 5 +      
ENSG00000168958 E004 0.0000000       2 227325239 227325244 6 +      
ENSG00000168958 E005 0.0000000       2 227325245 227325249 5 +      
ENSG00000168958 E006 0.0000000       2 227325250 227325250 1 +      
ENSG00000168958 E007 0.0000000       2 227325251 227325256 6 +      
ENSG00000168958 E008 0.0000000       2 227325257 227325258 2 +      
ENSG00000168958 E009 0.0000000       2 227325259 227325260 2 +      
ENSG00000168958 E010 0.0000000       2 227325261 227325261 1 +      
ENSG00000168958 E011 0.0000000       2 227325262 227325264 3 +      
ENSG00000168958 E012 0.0000000       2 227325265 227325267 3 +      
ENSG00000168958 E013 0.0000000       2 227325268 227325270 3 +      
ENSG00000168958 E014 0.0000000       2 227325271 227325275 5 +      
ENSG00000168958 E015 0.0000000       2 227325276 227325364 89 +      
ENSG00000168958 E016 0.0000000       2 227325365 227325427 63 +      
ENSG00000168958 E017 0.0000000       2 227325428 227325442 15 +      
ENSG00000168958 E018 0.0000000       2 227325443 227325450 8 +      
ENSG00000168958 E019 0.0000000       2 227325451 227325542 92 +      
ENSG00000168958 E020 0.0000000       2 227325543 227325660 118 +      
ENSG00000168958 E021 12.2417229 0.0011557911 9.332810e-03 0.076906916 2 227328678 227328789 112 + 1.215 1.004 -0.760
ENSG00000168958 E022 0.7532517 0.0133332379 7.992032e-02 0.290178165 2 227328790 227328899 110 + 0.092 0.355 2.414
ENSG00000168958 E023 3.0200314 0.0129621654 9.309783e-05 0.002241580 2 227328900 227329484 585 + 0.233 0.800 2.900
ENSG00000168958 E024 0.8708828 0.0130817715 2.228841e-01 0.510317141 2 227329485 227329605 121 + 0.169 0.355 1.414
ENSG00000168958 E025 1.8397943 0.0074231357 7.094138e-01 0.882448176 2 227329606 227329659 54 + 0.425 0.480 0.285
ENSG00000168958 E026 2.0758136 0.0070552145 9.076878e-01 0.970698400 2 227329660 227329697 38 + 0.496 0.480 -0.078
ENSG00000168958 E027 3.6558223 0.0047490395 5.771084e-01 0.810946954 2 227329698 227329783 86 + 0.702 0.632 -0.295
ENSG00000168958 E028 6.5701113 0.0588901545 5.816259e-02 0.241402008 2 227329784 227330594 811 + 0.722 0.993 1.052
ENSG00000168958 E029 0.3622142 0.0166368375 6.226590e-01   2 227330595 227330625 31 + 0.169 0.098 -0.908
ENSG00000168958 E030 20.0242022 0.0014074273 5.129680e-03 0.050581589 2 227330626 227330700 75 + 1.405 1.222 -0.640
ENSG00000168958 E031 24.1648584 0.0008507141 8.123366e-03 0.069809787 2 227330701 227330780 80 + 1.473 1.316 -0.541
ENSG00000168958 E032 27.5801534 0.0006458940 6.763658e-03 0.061640948 2 227330781 227330846 66 + 1.525 1.376 -0.514
ENSG00000168958 E033 60.9727498 0.0019033765 4.180830e-02 0.198949065 2 227332419 227332588 170 + 1.830 1.751 -0.268
ENSG00000168958 E034 46.2771222 0.0070510328 3.993737e-01 0.683196489 2 227340292 227340380 89 + 1.695 1.653 -0.144
ENSG00000168958 E035 0.8793806 0.0122774295 4.153109e-02 0.198084326 2 227340381 227340561 181 + 0.092 0.401 2.677
ENSG00000168958 E036 9.7870408 0.0318224664 9.077927e-01 0.970698594 2 227342745 227342819 75 + 1.040 1.025 -0.052
ENSG00000168958 E037 2.6133435 0.0075459523 3.612408e-02 0.182494948 2 227346228 227346315 88 + 0.384 0.680 1.414
ENSG00000168958 E038 5.8565925 0.0335638692 1.897092e-03 0.024583799 2 227346725 227347225 501 + 0.585 0.993 1.637
ENSG00000168958 E039 31.1017304 0.0005121118 1.368681e-01 0.393766205 2 227347226 227347384 159 + 1.543 1.467 -0.260
ENSG00000168958 E040 11.5289147 0.0012576976 4.189309e-04 0.007602497 2 227351681 227352513 833 + 0.922 1.222 1.092
ENSG00000168958 E041 25.3846000 0.0007526014 4.298922e-01 0.707938861 2 227352514 227352573 60 + 1.397 1.444 0.162
ENSG00000168958 E042 5.2994505 0.0437262412 2.955447e-01 0.588698287 2 227355298 227355676 379 + 0.722 0.864 0.566
ENSG00000168958 E043 48.6162391 0.0003321692 3.684766e-02 0.184851790 2 227355677 227355761 85 + 1.650 1.737 0.297
ENSG00000168958 E044 48.6440152 0.0015400021 2.961422e-01 0.589203761 2 227356986 227357119 134 + 1.672 1.719 0.158
ENSG00000168958 E045 91.1673564 0.0004510324 1.487917e-01 0.410860641 2 227357120 227357836 717 + 1.942 1.986 0.147
ENSG00000168958 E046 0.2374063 0.2315743520 3.152831e-01   2 227360495 227360523 29 + 0.169 0.000 -9.180

Help

Please Click HERE to learn more details about the results from DEXseq.