ENSG00000169180

1 Isoform Switch

Summary Plot

Only the isoforms with fraction > 5% are shown below.

  • Note:

    • About the Coding Potential: Please check the spreadsheet in the “Results” tag to confirm the coding potential. The above figure only show the predicted coding potential. The “gene_biotype” in the result spreadsheet is from the database record. Therefore, if you find conflicts between “gene_biotype” and “codingPotential”, please trust the “gene_biotype”.

    • Notes on IDR and IDR_w_binding: As the prediction of Intrinsically Disordered Regions (IDR) and Intrinsically Disordered Binding Regions (IDBR) are done by two different tools we require two things to annotate the Intrinsically Disordered Binding Regions (IDBR). Firstly the IDBR (predicted by ANCHOR2) must be a region of at least 15 amino acids (after the smoothing). Secondly the fraction of the IDBR which overlaps the IDR predictions (done by IUPred3, again after smoothing) must be at least 80%. When that is the case the IDR type will be annotated as “IDR_w_binding_region” instead of just “IDR”. The current default parameters have not been rigorously tested and should be considered experimental.

    • For the function of any other domain, please Click HERE to search it through Pfam database.

Results

isoform_id gene_id condition_1 condition_2 gene_name gene_biotype iso_biotype gene_overall_mean gene_value_1 gene_value_2 gene_stderr_1 gene_stderr_2 gene_log2_fold_change iso_overall_mean iso_value_1 iso_value_2 iso_stderr_1 iso_stderr_2 iso_log2_fold_change IF_overall IF1 IF2 dIF isoform_switch_q_value gene_switch_q_value PTC codingPotential
ENST00000304658 ENSG00000169180 No_inf pgKDN_inf XPO6 protein_coding protein_coding 57.86438 46.49457 59.44688 3.334028 2.619656 0.3544712 16.844921 8.195344 20.767888 0.3868846 1.6892883 1.3404133 0.28459167 0.178725 0.351350 0.172625 0.04460873 0.04460873 FALSE TRUE
ENST00000566175 ENSG00000169180 No_inf pgKDN_inf XPO6 protein_coding nonsense_mediated_decay 57.86438 46.49457 59.44688 3.334028 2.619656 0.3544712 1.936424 2.704556 0.000000 2.7045557 0.0000000 -8.0845723 0.02998333 0.050350 0.000000 -0.050350 0.83578623 0.04460873   FALSE
MSTRG.10906.1 ENSG00000169180 No_inf pgKDN_inf XPO6 protein_coding   57.86438 46.49457 59.44688 3.334028 2.619656 0.3544712 15.609450 10.492039 20.177708 1.7850512 1.4768125 0.9428077 0.26814167 0.227150 0.341075 0.113925 0.44043779 0.04460873 FALSE TRUE
MSTRG.10906.2 ENSG00000169180 No_inf pgKDN_inf XPO6 protein_coding   57.86438 46.49457 59.44688 3.334028 2.619656 0.3544712 5.682541 7.948898 3.166351 0.6573356 2.0323815 -1.3251985 0.10775833 0.176100 0.054350 -0.121750 0.31528274 0.04460873 FALSE TRUE
MSTRG.10906.5 ENSG00000169180 No_inf pgKDN_inf XPO6 protein_coding   57.86438 46.49457 59.44688 3.334028 2.619656 0.3544712 4.225384 5.193983 2.961851 0.3099416 0.4748658 -0.8082547 0.07712500 0.113600 0.050000 -0.063600 0.26409325 0.04460873 FALSE TRUE
  • Note:
    • The comparisons made can be identified as “from ‘condition_1’ to ‘condition_2’”, meaning ‘condition_1’ is considered the ground state and ‘condition_2’ the changed state. This also means that a positive dIF value indicates that the isoform usage is increased in ‘condition_2’ compared to ‘condition_1’. Since the ‘isoformFeatures’ entry is the most relevant part of the switchAnalyzeRlist object, the most-used standard methods have also been implemented to work directly on isoformFeatures.

Help

Please Click HERE to learn more details about the results of IsoformSwitchAnalyzeR.

2 Differential Exon Usage

Counts

All exons whithin this gene region are shown and numbering below.

Expression

All exons whithin this gene region are shown and numbering below.

Splicing

All exons whithin this gene region are shown and numbering below.

Transcripts

All isoforms whithin this gene region are shown below.

Results

groupID featureID exonBaseMean dispersion pvalue padj seqnames start end width strand pgKDN.inf No.inf log2fold_No.inf_pgKDN.inf
ENSG00000169180 E001 0.6135291 0.6713951107 6.507449e-01 8.529729e-01 16 28097976 28097978 3 - 0.146 0.278 1.167
ENSG00000169180 E002 0.8584220 0.1889907384 4.568055e-01 7.289927e-01 16 28097979 28097992 14 - 0.204 0.342 0.996
ENSG00000169180 E003 1.2304211 0.0843923999 2.619689e-01 5.547105e-01 16 28097993 28097994 2 - 0.255 0.446 1.166
ENSG00000169180 E004 144.7241559 0.0001121904 5.354881e-03 5.207540e-02 16 28097995 28098618 624 - 2.127 2.197 0.231
ENSG00000169180 E005 26.6751795 0.0005098110 4.115976e-01 6.931372e-01 16 28098619 28098639 21 - 1.415 1.464 0.169
ENSG00000169180 E006 1.9883026 0.0072318823 2.282238e-02 1.376963e-01 16 28101055 28101269 215 - 0.301 0.633 1.718
ENSG00000169180 E007 1.6035239 0.0447216734 1.493160e-01 4.115499e-01 16 28101270 28101457 188 - 0.301 0.531 1.258
ENSG00000169180 E008 64.3217245 0.0002267391 9.707978e-01 9.942297e-01 16 28101458 28101649 192 - 1.808 1.811 0.011
ENSG00000169180 E009 27.5449046 0.0005659656 3.984077e-01 6.823221e-01 16 28101650 28101688 39 - 1.469 1.422 -0.160
ENSG00000169180 E010 46.1559888 0.0003214772 6.968576e-01 8.762517e-01 16 28101847 28101945 99 - 1.674 1.659 -0.052
ENSG00000169180 E011 0.2448930 0.0163825469 7.575056e-01   16 28101946 28101986 41 - 0.079 0.114 0.581
ENSG00000169180 E012 58.1027297 0.0002934452 2.112889e-01 4.961968e-01 16 28104546 28104707 162 - 1.744 1.795 0.172
ENSG00000169180 E013 0.2441377 0.0163548595 7.572549e-01   16 28105689 28106042 354 - 0.079 0.114 0.580
ENSG00000169180 E014 34.9117936 0.0081054369 6.301494e-01 8.413867e-01 16 28106043 28106111 69 - 1.537 1.567 0.104
ENSG00000169180 E015 39.9824218 0.0114109434 2.728686e-01 5.666446e-01 16 28106112 28106214 103 - 1.575 1.647 0.245
ENSG00000169180 E016 26.8034306 0.0008090115 4.493780e-01 7.231560e-01 16 28106383 28106452 70 - 1.419 1.464 0.158
ENSG00000169180 E017 20.3686401 0.0007101253 2.361969e-01 5.254188e-01 16 28106453 28106497 45 - 1.354 1.278 -0.268
ENSG00000169180 E018 13.6784192 0.0011088640 1.543315e-01 4.196903e-01 16 28107522 28107528 7 - 1.204 1.092 -0.400
ENSG00000169180 E019 25.9640032 0.0015712741 3.399074e-01 6.315912e-01 16 28107529 28107587 59 - 1.448 1.392 -0.193
ENSG00000169180 E020 33.3304057 0.0004188723 7.219194e-01 8.881589e-01 16 28107588 28107677 90 - 1.521 1.542 0.070
ENSG00000169180 E021 0.1271363 0.0124109502 3.567661e-01   16 28111730 28111816 87 - 0.000 0.114 12.170
ENSG00000169180 E022 39.0673525 0.0004262028 5.693374e-01 8.063702e-01 16 28111817 28111942 126 - 1.585 1.614 0.100
ENSG00000169180 E023 22.2880934 0.0006272233 6.043651e-01 8.274383e-01 16 28111943 28112006 64 - 1.347 1.381 0.119
ENSG00000169180 E024 29.1728013 0.0005048047 8.485123e-01 9.463588e-01 16 28112904 28113050 147 - 1.477 1.469 -0.030
ENSG00000169180 E025 1.2170764 0.0519470919 9.819204e-01 9.984333e-01 16 28117037 28117317 281 - 0.343 0.342 -0.005
ENSG00000169180 E026 37.8101178 0.0027875260 9.943010e-01 1.000000e+00 16 28117318 28117462 145 - 1.582 1.584 0.007
ENSG00000169180 E027 35.5643634 0.0004280671 1.532570e-02 1.066963e-01 16 28121670 28121762 93 - 1.605 1.482 -0.420
ENSG00000169180 E028 34.0707144 0.0011275754 1.527225e-01 4.168912e-01 16 28125689 28125768 80 - 1.569 1.495 -0.253
ENSG00000169180 E029 25.5500490 0.0011119060 8.227660e-01 9.356232e-01 16 28125769 28125828 60 - 1.412 1.427 0.053
ENSG00000169180 E030 11.1915605 0.0148360655 8.431205e-01 9.438511e-01 16 28125829 28125831 3 - 1.072 1.093 0.074
ENSG00000169180 E031 12.1453938 0.0138951072 8.416558e-01 9.431903e-01 16 28125832 28125848 17 - 1.121 1.103 -0.065
ENSG00000169180 E032 0.0000000       16 28126618 28126760 143 -      
ENSG00000169180 E033 20.4748849 0.0044440820 1.923073e-01 4.722657e-01 16 28132334 28132397 64 - 1.362 1.271 -0.318
ENSG00000169180 E034 14.1512074 0.0027042560 9.498353e-02 3.206787e-01 16 28132398 28132403 6 - 1.226 1.093 -0.475
ENSG00000169180 E035 28.6781549 0.0015479925 7.168941e-01 8.859171e-01 16 28133841 28133930 90 - 1.475 1.455 -0.066
ENSG00000169180 E036 9.6626975 0.0015091690 1.589095e-01 4.260183e-01 16 28133931 28133933 3 - 0.964 1.093 0.471
ENSG00000169180 E037 23.5162256 0.0013007408 5.237845e-01 7.769257e-01 16 28135216 28135324 109 - 1.366 1.407 0.144
ENSG00000169180 E038 0.1186381 0.0118876139 8.094514e-01   16 28146091 28146093 3 - 0.079 0.000 -12.273
ENSG00000169180 E039 17.7147733 0.0007781896 4.307024e-01 7.085378e-01 16 28146094 28146161 68 - 1.288 1.235 -0.188
ENSG00000169180 E040 11.9271816 0.0025614016 7.463585e-01 8.996729e-01 16 28146162 28146171 10 - 1.094 1.123 0.105
ENSG00000169180 E041 13.9786694 0.0010079527 9.675104e-01 9.934121e-01 16 28146172 28146203 32 - 1.171 1.169 -0.004
ENSG00000169180 E042 0.1186381 0.0118876139 8.094514e-01   16 28146204 28146303 100 - 0.079 0.000 -12.273
ENSG00000169180 E043 25.3952871 0.0010062200 8.919234e-01 9.641356e-01 16 28152659 28152785 127 - 1.419 1.412 -0.022
ENSG00000169180 E044 2.7305971 0.1708723275 9.211759e-02 3.152532e-01 16 28152786 28152929 144 - 0.380 0.740 1.680
ENSG00000169180 E045 2.7367966 0.3065379935 7.924082e-02 2.886924e-01 16 28152930 28152964 35 - 0.342 0.763 1.998
ENSG00000169180 E046 22.8248016 0.0012720055 8.589198e-14 1.290389e-11 16 28152965 28154197 1233 - 1.108 1.584 1.664
ENSG00000169180 E047 1.2512260 0.0109613045 1.100330e-02 8.559341e-02 16 28154588 28154612 25 - 0.146 0.531 2.580
ENSG00000169180 E048 2.4923482 0.0061725712 1.808417e-03 2.363916e-02 16 28155597 28155701 105 - 0.301 0.740 2.165
ENSG00000169180 E049 2.3369487 0.0157948157 1.329392e-01 3.871580e-01 16 28155702 28155771 70 - 0.415 0.633 1.040
ENSG00000169180 E050 2.9455296 0.0047898761 1.728992e-01 4.458649e-01 16 28155772 28155945 174 - 0.505 0.689 0.821
ENSG00000169180 E051 1.6144408 0.0205723858 4.048917e-02 1.951687e-01 16 28155946 28155975 30 - 0.255 0.567 1.751
ENSG00000169180 E052 15.9619716 0.0009425030 4.423221e-01 7.176956e-01 16 28156074 28156132 59 - 1.199 1.257 0.204
ENSG00000169180 E053 32.7198062 0.0004573766 9.894846e-01 1.000000e+00 16 28156133 28156314 182 - 1.521 1.523 0.004
ENSG00000169180 E054 29.1487595 0.0034451623 2.760162e-02 1.549887e-01 16 28156315 28156527 213 - 1.524 1.392 -0.456
ENSG00000169180 E055 0.2441377 0.0163548595 7.572549e-01   16 28165271 28165419 149 - 0.079 0.114 0.580
ENSG00000169180 E056 15.0488689 0.0010095017 6.061236e-01 8.284945e-01 16 28166508 28166585 78 - 1.215 1.178 -0.132
ENSG00000169180 E057 16.3743678 0.0023072033 4.649672e-01 7.342704e-01 16 28169750 28169844 95 - 1.256 1.203 -0.185
ENSG00000169180 E058 12.8209488 0.0010781399 1.307420e-01 3.835152e-01 16 28169845 28169909 65 - 1.182 1.060 -0.440
ENSG00000169180 E059 0.1170040 0.0117208337 8.095305e-01   16 28173065 28173122 58 - 0.079 0.000 -12.274
ENSG00000169180 E060 21.1932984 0.0006671983 6.674234e-04 1.093201e-02 16 28175898 28176057 160 - 1.422 1.195 -0.793
ENSG00000169180 E061 10.8252306 0.0090665802 1.315753e-02 9.609185e-02 16 28176058 28176095 38 - 1.153 0.913 -0.879
ENSG00000169180 E062 17.2150144 0.0007937279 7.009195e-04 1.137286e-02 16 28177220 28177332 113 - 1.343 1.093 -0.886
ENSG00000169180 E063 11.1310836 0.0028072627 9.057685e-06 3.137554e-04 16 28180941 28181031 91 - 1.210 0.784 -1.580
ENSG00000169180 E064 0.0000000       16 28181032 28181122 91 -      
ENSG00000169180 E065 0.9602512 0.0265936301 3.774291e-01 6.644123e-01 16 28208987 28209055 69 - 0.343 0.204 -1.005
ENSG00000169180 E066 0.2530140 0.2900974701 1.857358e-01   16 28209056 28209122 67 - 0.000 0.204 12.161
ENSG00000169180 E067 23.3302065 0.0018805965 1.672372e-02 1.127753e-01 16 28211366 28211965 600 - 1.438 1.285 -0.533

Help

Please Click HERE to learn more details about the results from DEXseq.