ENSG00000169221

1 Isoform Switch

Summary Plot

Only the isoforms with fraction > 5% are shown below.

  • Note:

    • About the Coding Potential: Please check the spreadsheet in the “Results” tag to confirm the coding potential. The above figure only show the predicted coding potential. The “gene_biotype” in the result spreadsheet is from the database record. Therefore, if you find conflicts between “gene_biotype” and “codingPotential”, please trust the “gene_biotype”.

    • Notes on IDR and IDR_w_binding: As the prediction of Intrinsically Disordered Regions (IDR) and Intrinsically Disordered Binding Regions (IDBR) are done by two different tools we require two things to annotate the Intrinsically Disordered Binding Regions (IDBR). Firstly the IDBR (predicted by ANCHOR2) must be a region of at least 15 amino acids (after the smoothing). Secondly the fraction of the IDBR which overlaps the IDR predictions (done by IUPred3, again after smoothing) must be at least 80%. When that is the case the IDR type will be annotated as “IDR_w_binding_region” instead of just “IDR”. The current default parameters have not been rigorously tested and should be considered experimental.

    • For the function of any other domain, please Click HERE to search it through Pfam database.

Results

isoform_id gene_id condition_1 condition_2 gene_name gene_biotype iso_biotype gene_overall_mean gene_value_1 gene_value_2 gene_stderr_1 gene_stderr_2 gene_log2_fold_change iso_overall_mean iso_value_1 iso_value_2 iso_stderr_1 iso_stderr_2 iso_log2_fold_change IF_overall IF1 IF2 dIF isoform_switch_q_value gene_switch_q_value PTC codingPotential
ENST00000409939 ENSG00000169221 No_inf pgKDN_inf TBC1D10B protein_coding protein_coding 26.20089 22.25618 27.29614 0.7663049 0.8824287 0.2943712 18.202963 11.503948 20.961025 0.6510730 0.2765379 0.8650148 0.68420000 0.518025 0.770775 0.25275 0.01426999 0.01426999 FALSE TRUE
ENST00000475650 ENSG00000169221 No_inf pgKDN_inf TBC1D10B protein_coding retained_intron 26.20089 22.25618 27.29614 0.7663049 0.8824287 0.2943712 4.153015 6.908668 2.996591 0.5467337 0.5832021 -1.2023656 0.16865000 0.310600 0.108450 -0.20215 0.03361959 0.01426999 FALSE TRUE
ENST00000478158 ENSG00000169221 No_inf pgKDN_inf TBC1D10B protein_coding retained_intron 26.20089 22.25618 27.29614 0.7663049 0.8824287 0.2943712 2.336684 2.979478 1.627172 0.1425862 0.2076506 -0.8686880 0.09245833 0.134275 0.059675 -0.07460 0.39256252 0.01426999 FALSE TRUE
  • Note:
    • The comparisons made can be identified as “from ‘condition_1’ to ‘condition_2’”, meaning ‘condition_1’ is considered the ground state and ‘condition_2’ the changed state. This also means that a positive dIF value indicates that the isoform usage is increased in ‘condition_2’ compared to ‘condition_1’. Since the ‘isoformFeatures’ entry is the most relevant part of the switchAnalyzeRlist object, the most-used standard methods have also been implemented to work directly on isoformFeatures.

Help

Please Click HERE to learn more details about the results of IsoformSwitchAnalyzeR.

2 Differential Exon Usage

Counts

All exons whithin this gene region are shown and numbering below.

Expression

All exons whithin this gene region are shown and numbering below.

Splicing

All exons whithin this gene region are shown and numbering below.

Transcripts

All isoforms whithin this gene region are shown below.

Results

groupID featureID exonBaseMean dispersion pvalue padj seqnames start end width strand pgKDN.inf No.inf log2fold_No.inf_pgKDN.inf
ENSG00000169221 E001 0.0000000       16 30357102 30357106 5 -      
ENSG00000169221 E002 178.2841073 0.0001120450 3.876579e-01 6.733769e-01 16 30357107 30358093 987 - 2.261 2.246 -0.049
ENSG00000169221 E003 73.1832820 0.0002190046 1.758339e-02 1.164468e-01 16 30358094 30358573 480 - 1.830 1.909 0.265
ENSG00000169221 E004 22.6337513 0.0006244089 6.628057e-01 8.594862e-01 16 30358663 30358775 113 - 1.360 1.387 0.095
ENSG00000169221 E005 15.8934066 0.0008712021 8.853999e-01 9.614604e-01 16 30358776 30358817 42 - 1.222 1.233 0.040
ENSG00000169221 E006 2.2471964 0.0062567277 8.274124e-03 7.073164e-02 16 30358818 30359171 354 - 0.284 0.666 1.980
ENSG00000169221 E007 8.6365409 0.0016462009 2.941412e-01 5.875480e-01 16 30359172 30359183 12 - 1.029 0.931 -0.361
ENSG00000169221 E008 25.7363591 0.0005868341 3.760720e-01 6.632788e-01 16 30359184 30359361 178 - 1.450 1.401 -0.171
ENSG00000169221 E009 1.4973478 0.0088401757 5.134731e-02 2.245079e-01 16 30359362 30359537 176 - 0.228 0.524 1.758
ENSG00000169221 E010 11.7845642 0.0055060750 8.978088e-02 3.112381e-01 16 30359538 30359603 66 - 1.171 1.026 -0.525
ENSG00000169221 E011 0.4981279 0.0156916461 2.660824e-01   16 30359604 30359674 71 - 0.090 0.250 1.757
ENSG00000169221 E012 8.5313967 0.0021987941 4.819651e-01 7.469628e-01 16 30359727 30359749 23 - 1.010 0.944 -0.242
ENSG00000169221 E013 6.4508678 0.0021887389 4.191167e-01 6.987592e-01 16 30359750 30359841 92 - 0.911 0.827 -0.322
ENSG00000169221 E014 0.0000000       16 30359842 30360176 335 -      
ENSG00000169221 E015 9.7945122 0.0593260389 6.859750e-01 8.703070e-01 16 30364900 30365006 107 - 1.009 1.057 0.173
ENSG00000169221 E016 13.2069744 0.0012575516 6.759360e-01 8.658253e-01 16 30365105 30365212 108 - 1.136 1.169 0.119
ENSG00000169221 E017 10.9712819 0.0015328149 6.203547e-01 8.358492e-01 16 30365495 30365594 100 - 1.098 1.057 -0.149
ENSG00000169221 E018 22.7290168 0.0006419067 2.550546e-10 2.421851e-08 16 30365595 30368007 2413 - 1.136 1.535 1.391
ENSG00000169221 E019 60.6910544 0.0002627719 1.020594e-05 3.472853e-04 16 30369228 30370494 1267 - 1.862 1.700 -0.546

Help

Please Click HERE to learn more details about the results from DEXseq.