ENSG00000169241

1 Isoform Switch

Summary Plot

Only the isoforms with fraction > 5% are shown below.

  • Note:

    • About the Coding Potential: Please check the spreadsheet in the “Results” tag to confirm the coding potential. The above figure only show the predicted coding potential. The “gene_biotype” in the result spreadsheet is from the database record. Therefore, if you find conflicts between “gene_biotype” and “codingPotential”, please trust the “gene_biotype”.

    • Notes on IDR and IDR_w_binding: As the prediction of Intrinsically Disordered Regions (IDR) and Intrinsically Disordered Binding Regions (IDBR) are done by two different tools we require two things to annotate the Intrinsically Disordered Binding Regions (IDBR). Firstly the IDBR (predicted by ANCHOR2) must be a region of at least 15 amino acids (after the smoothing). Secondly the fraction of the IDBR which overlaps the IDR predictions (done by IUPred3, again after smoothing) must be at least 80%. When that is the case the IDR type will be annotated as “IDR_w_binding_region” instead of just “IDR”. The current default parameters have not been rigorously tested and should be considered experimental.

    • For the function of any other domain, please Click HERE to search it through Pfam database.

Results

isoform_id gene_id condition_1 condition_2 gene_name gene_biotype iso_biotype gene_overall_mean gene_value_1 gene_value_2 gene_stderr_1 gene_stderr_2 gene_log2_fold_change iso_overall_mean iso_value_1 iso_value_2 iso_stderr_1 iso_stderr_2 iso_log2_fold_change IF_overall IF1 IF2 dIF isoform_switch_q_value gene_switch_q_value PTC codingPotential
ENST00000303343 ENSG00000169241 No_inf pgKDN_inf SLC50A1 protein_coding protein_coding 27.28182 21.16473 29.86 0.9739221 1.77853 0.4963536 1.8437250 0.0000000 4.689239 0.0000000 1.3046650 8.8762833 0.061550 0.00000 0.151350 0.151350 0.0000113815 1.13815e-05 FALSE TRUE
ENST00000368401 ENSG00000169241 No_inf pgKDN_inf SLC50A1 protein_coding protein_coding 27.28182 21.16473 29.86 0.9739221 1.77853 0.4963536 6.3751086 5.9527912 3.380532 0.9914906 1.9713175 -0.8144761 0.233850 0.28280 0.119925 -0.162875 0.4595651582 1.13815e-05 FALSE TRUE
ENST00000368404 ENSG00000169241 No_inf pgKDN_inf SLC50A1 protein_coding protein_coding 27.28182 21.16473 29.86 0.9739221 1.77853 0.4963536 6.5527710 6.7908271 7.398683 2.6046466 2.8943375 0.1235068 0.265450 0.33875 0.261650 -0.077100 0.9466937445 1.13815e-05 FALSE TRUE
ENST00000490276 ENSG00000169241 No_inf pgKDN_inf SLC50A1 protein_coding nonsense_mediated_decay 27.28182 21.16473 29.86 0.9739221 1.77853 0.4963536 1.1562685 0.2578071 2.344976 0.2578071 1.0262565 3.1364464 0.040375 0.01250 0.077450 0.064950 0.4498246785 1.13815e-05 FALSE FALSE
ENST00000506037 ENSG00000169241 No_inf pgKDN_inf SLC50A1 protein_coding retained_intron 27.28182 21.16473 29.86 0.9739221 1.77853 0.4963536 1.5624158 1.8570899 1.183983 0.4982793 0.4363099 -0.6450090 0.061275 0.08685 0.042575 -0.044275 0.6835462684 1.13815e-05   FALSE
ENST00000622581 ENSG00000169241 No_inf pgKDN_inf SLC50A1 protein_coding protein_coding 27.28182 21.16473 29.86 0.9739221 1.77853 0.4963536 0.8834487 2.6503460 0.000000 2.6503460 0.0000000 -8.0554701 0.036900 0.11070 0.000000 -0.110700 0.8350142258 1.13815e-05 FALSE TRUE
MSTRG.1951.10 ENSG00000169241 No_inf pgKDN_inf SLC50A1 protein_coding   27.28182 21.16473 29.86 0.9739221 1.77853 0.4963536 3.4218064 0.0000000 3.773707 0.0000000 2.8975687 8.5636564 0.104525 0.00000 0.115725 0.115725 0.5371173504 1.13815e-05 TRUE TRUE
  • Note:
    • The comparisons made can be identified as “from ‘condition_1’ to ‘condition_2’”, meaning ‘condition_1’ is considered the ground state and ‘condition_2’ the changed state. This also means that a positive dIF value indicates that the isoform usage is increased in ‘condition_2’ compared to ‘condition_1’. Since the ‘isoformFeatures’ entry is the most relevant part of the switchAnalyzeRlist object, the most-used standard methods have also been implemented to work directly on isoformFeatures.

Help

Please Click HERE to learn more details about the results of IsoformSwitchAnalyzeR.

2 Differential Exon Usage

Counts

All exons whithin this gene region are shown and numbering below.

Expression

All exons whithin this gene region are shown and numbering below.

Splicing

All exons whithin this gene region are shown and numbering below.

Transcripts

All isoforms whithin this gene region are shown below.

Results

groupID featureID exonBaseMean dispersion pvalue padj seqnames start end width strand pgKDN.inf No.inf log2fold_No.inf_pgKDN.inf
ENSG00000169241 E001 0.4792182 0.0168540605 0.380787263   1 155135344 155135356 13 + 0.226 0.101 -1.382
ENSG00000169241 E002 1.5654134 0.0860479355 0.300736901 0.59364709 1 155135357 155135390 34 + 0.485 0.312 -0.966
ENSG00000169241 E003 1.1953953 0.0109655308 0.078031345 0.28576500 1 155135391 155135392 2 + 0.451 0.183 -1.797
ENSG00000169241 E004 3.1257557 0.0047710402 0.037204022 0.18570678 1 155135393 155135598 206 + 0.727 0.453 -1.237
ENSG00000169241 E005 1.4771406 0.0186866646 0.441897814 0.71726606 1 155135599 155135680 82 + 0.331 0.453 0.689
ENSG00000169241 E006 0.1272623 0.0123076250 0.478856897   1 155135681 155135692 12 + 0.000 0.101 11.183
ENSG00000169241 E007 0.3804973 0.0165009714 0.082230599   1 155135812 155135827 16 + 0.000 0.252 12.612
ENSG00000169241 E008 0.3804973 0.0165009714 0.082230599   1 155135828 155135839 12 + 0.000 0.252 12.612
ENSG00000169241 E009 0.8887913 0.0127418901 0.002798965 0.03275317 1 155135840 155135849 10 + 0.000 0.453 13.655
ENSG00000169241 E010 0.8887913 0.0127418901 0.002798965 0.03275317 1 155135850 155135851 2 + 0.000 0.453 13.655
ENSG00000169241 E011 1.4853229 0.0100499164 0.175584370 0.44966607 1 155135852 155135857 6 + 0.282 0.491 1.203
ENSG00000169241 E012 1.8385957 0.0113296761 0.630405146 0.84149963 1 155135858 155135858 1 + 0.414 0.491 0.396
ENSG00000169241 E013 2.3273466 0.0449871663 0.648258878 0.85145511 1 155135859 155135866 8 + 0.485 0.559 0.356
ENSG00000169241 E014 4.6600780 0.0034207896 0.491129877 0.75354064 1 155135867 155135896 30 + 0.708 0.796 0.355
ENSG00000169241 E015 10.1495861 0.0049336474 0.667154033 0.86152588 1 155135897 155135972 76 + 1.024 1.071 0.169
ENSG00000169241 E016 6.1087260 0.0639978078 0.965552350 0.99277667 1 155135973 155135991 19 + 0.841 0.863 0.088
ENSG00000169241 E017 0.9694423 0.0127012700 0.590736037 0.81886807 1 155135992 155135997 6 + 0.331 0.252 -0.534
ENSG00000169241 E018 7.7112201 0.0027752630 0.549807907 0.79452708 1 155136299 155136315 17 + 0.907 0.973 0.249
ENSG00000169241 E019 13.0897680 0.0105920056 0.622768275 0.83751114 1 155136316 155136376 61 + 1.124 1.174 0.176
ENSG00000169241 E020 0.3813786 0.0210356583 0.083085899   1 155136377 155136396 20 + 0.000 0.252 12.603
ENSG00000169241 E021 0.6086803 0.0161988309 0.752096712 0.90241566 1 155136397 155136827 431 + 0.226 0.183 -0.382
ENSG00000169241 E022 15.5756244 0.0009763765 0.189967910 0.46891209 1 155136828 155136951 124 + 1.258 1.174 -0.298
ENSG00000169241 E023 1.8368660 0.5235029292 0.999059920 1.00000000 1 155136952 155137131 180 + 0.451 0.453 0.010
ENSG00000169241 E024 9.4129278 0.0015666471 0.857212917 0.94996551 1 155137561 155137578 18 + 1.005 1.030 0.091
ENSG00000169241 E025 21.5360634 0.0006949398 0.614707604 0.83263153 1 155137579 155137722 144 + 1.333 1.373 0.138
ENSG00000169241 E026 17.3635798 0.0008676949 0.700740064 0.87812715 1 155137979 155138047 69 + 1.247 1.282 0.122
ENSG00000169241 E027 15.7933077 0.0009226338 0.066375740 0.25950618 1 155138048 155138098 51 + 1.279 1.158 -0.428
ENSG00000169241 E028 1.0750815 0.2044946540 0.060949000 0.24786784 1 155138162 155138179 18 + 0.451 0.101 -2.799
ENSG00000169241 E029 42.4534552 0.0068083417 0.327265839 0.61980321 1 155138180 155138509 330 + 1.656 1.617 -0.130
ENSG00000169241 E030 13.2388040 0.0074138541 0.457577910 0.72943596 1 155138510 155138593 84 + 1.117 1.189 0.257
ENSG00000169241 E031 14.6942740 0.0009467193 0.507007863 0.76561518 1 155138594 155138759 166 + 1.167 1.224 0.203
ENSG00000169241 E032 5.6264724 0.0055287046 0.915570746 0.97353141 1 155138760 155138857 98 + 0.811 0.831 0.078
ENSG00000169241 E033 0.0000000       1 155153005 155153046 42 +      

Help

Please Click HERE to learn more details about the results from DEXseq.