ENSG00000169592

1 Isoform Switch

Summary Plot

Only the isoforms with fraction > 5% are shown below.

  • Note:

    • About the Coding Potential: Please check the spreadsheet in the “Results” tag to confirm the coding potential. The above figure only show the predicted coding potential. The “gene_biotype” in the result spreadsheet is from the database record. Therefore, if you find conflicts between “gene_biotype” and “codingPotential”, please trust the “gene_biotype”.

    • Notes on IDR and IDR_w_binding: As the prediction of Intrinsically Disordered Regions (IDR) and Intrinsically Disordered Binding Regions (IDBR) are done by two different tools we require two things to annotate the Intrinsically Disordered Binding Regions (IDBR). Firstly the IDBR (predicted by ANCHOR2) must be a region of at least 15 amino acids (after the smoothing). Secondly the fraction of the IDBR which overlaps the IDR predictions (done by IUPred3, again after smoothing) must be at least 80%. When that is the case the IDR type will be annotated as “IDR_w_binding_region” instead of just “IDR”. The current default parameters have not been rigorously tested and should be considered experimental.

    • For the function of any other domain, please Click HERE to search it through Pfam database.

Results

isoform_id gene_id condition_1 condition_2 gene_name gene_biotype iso_biotype gene_overall_mean gene_value_1 gene_value_2 gene_stderr_1 gene_stderr_2 gene_log2_fold_change iso_overall_mean iso_value_1 iso_value_2 iso_stderr_1 iso_stderr_2 iso_log2_fold_change IF_overall IF1 IF2 dIF isoform_switch_q_value gene_switch_q_value PTC codingPotential
ENST00000563197 ENSG00000169592 No_inf pgKDN_inf INO80E protein_coding protein_coding 47.39312 51.68837 44.86521 2.294667 1.657847 -0.2041999 16.910753 16.916266 13.785110 1.087219 4.8628842 -0.2951068 0.35776667 0.328175 0.301275 -0.026900 9.012126e-01 8.466131e-10 FALSE TRUE
ENST00000567254 ENSG00000169592 No_inf pgKDN_inf INO80E protein_coding protein_coding 47.39312 51.68837 44.86521 2.294667 1.657847 -0.2041999 1.730578 0.000000 3.311517 0.000000 0.7826417 8.3756987 0.03737500 0.000000 0.073650 0.073650 5.442044e-06 8.466131e-10 FALSE TRUE
ENST00000567705 ENSG00000169592 No_inf pgKDN_inf INO80E protein_coding protein_coding 47.39312 51.68837 44.86521 2.294667 1.657847 -0.2041999 1.238789 0.000000 3.716368 0.000000 3.7163684 8.5416265 0.03011667 0.000000 0.090350 0.090350 8.404370e-01 8.466131e-10 FALSE TRUE
ENST00000568043 ENSG00000169592 No_inf pgKDN_inf INO80E protein_coding retained_intron 47.39312 51.68837 44.86521 2.294667 1.657847 -0.2041999 4.113949 5.042721 3.805510 1.303937 1.6387453 -0.4051847 0.08566667 0.096650 0.084250 -0.012400 8.787421e-01 8.466131e-10 FALSE FALSE
ENST00000620599 ENSG00000169592 No_inf pgKDN_inf INO80E protein_coding protein_coding 47.39312 51.68837 44.86521 2.294667 1.657847 -0.2041999 3.574860 0.000000 5.446678 0.000000 0.4966343 9.0918791 0.07846667 0.000000 0.122200 0.122200 8.466131e-10 8.466131e-10 FALSE TRUE
MSTRG.10993.5 ENSG00000169592 No_inf pgKDN_inf INO80E protein_coding   47.39312 51.68837 44.86521 2.294667 1.657847 -0.2041999 3.678924 4.785181 3.209872 2.763339 1.6157211 -0.5745818 0.07827500 0.097350 0.069425 -0.027925 9.054949e-01 8.466131e-10 FALSE TRUE
MSTRG.10993.7 ENSG00000169592 No_inf pgKDN_inf INO80E protein_coding   47.39312 51.68837 44.86521 2.294667 1.657847 -0.2041999 3.426253 7.944932 0.000000 2.654089 0.0000000 -9.6357058 0.07069167 0.157500 0.000000 -0.157500 1.262380e-02 8.466131e-10 TRUE FALSE
  • Note:
    • The comparisons made can be identified as “from ‘condition_1’ to ‘condition_2’”, meaning ‘condition_1’ is considered the ground state and ‘condition_2’ the changed state. This also means that a positive dIF value indicates that the isoform usage is increased in ‘condition_2’ compared to ‘condition_1’. Since the ‘isoformFeatures’ entry is the most relevant part of the switchAnalyzeRlist object, the most-used standard methods have also been implemented to work directly on isoformFeatures.

Help

Please Click HERE to learn more details about the results of IsoformSwitchAnalyzeR.

2 Differential Exon Usage

Counts

All exons whithin this gene region are shown and numbering below.

Expression

All exons whithin this gene region are shown and numbering below.

Splicing

All exons whithin this gene region are shown and numbering below.

Transcripts

All isoforms whithin this gene region are shown below.

Results

groupID featureID exonBaseMean dispersion pvalue padj seqnames start end width strand pgKDN.inf No.inf log2fold_No.inf_pgKDN.inf
ENSG00000169592 E001 0.1265070 0.0123044818 1.000000e+00   16 29995715 29996162 448 + 0.000 0.066 8.276
ENSG00000169592 E002 0.2536433 0.0159164894 6.754498e-01   16 29996163 29996200 38 + 0.000 0.123 11.455
ENSG00000169592 E003 0.2543986 0.0159458530 6.753742e-01   16 29996201 29996209 9 + 0.000 0.123 11.455
ENSG00000169592 E004 0.2543986 0.0159458530 6.753742e-01   16 29996210 29996217 8 + 0.000 0.123 11.455
ENSG00000169592 E005 1.1341578 0.0132698445 1.653291e-01 4.349901e-01 16 29996218 29996237 20 + 0.135 0.364 1.843
ENSG00000169592 E006 1.3884305 0.0459519153 9.854576e-02 3.275434e-01 16 29996238 29996240 3 + 0.135 0.421 2.165
ENSG00000169592 E007 1.5054318 0.0263561607 2.703743e-01 5.640056e-01 16 29996241 29996243 3 + 0.238 0.421 1.165
ENSG00000169592 E008 1.5054318 0.0263561607 2.703743e-01 5.640056e-01 16 29996244 29996245 2 + 0.238 0.421 1.165
ENSG00000169592 E009 1.8768345 0.0176752704 3.500021e-01 6.402025e-01 16 29996246 29996249 4 + 0.322 0.472 0.843
ENSG00000169592 E010 1.9938385 0.0221197398 6.113431e-01 8.308705e-01 16 29996250 29996250 1 + 0.391 0.472 0.428
ENSG00000169592 E011 2.3652384 0.0296345507 6.740305e-01 8.649499e-01 16 29996251 29996251 1 + 0.451 0.518 0.329
ENSG00000169592 E012 4.2433659 0.0037497408 3.367965e-01 6.288168e-01 16 29996252 29996261 10 + 0.594 0.721 0.543
ENSG00000169592 E013 6.8266895 0.0024842931 9.835828e-01 9.986903e-01 16 29996262 29996273 12 + 0.858 0.859 0.003
ENSG00000169592 E014 27.5567279 0.0046722068 2.060451e-04 4.293986e-03 16 29996274 29996391 118 + 1.566 1.335 -0.795
ENSG00000169592 E015 3.0645542 0.0174363029 9.115515e-02 3.135934e-01 16 29996392 29996546 155 + 0.731 0.496 -1.041
ENSG00000169592 E016 29.8996290 0.0006250676 2.981229e-05 8.607581e-04 16 29996547 29996617 71 + 1.599 1.370 -0.787
ENSG00000169592 E017 0.4996734 0.0338697657 8.472081e-01   16 29996618 29996807 190 + 0.135 0.174 0.428
ENSG00000169592 E018 32.7103092 0.0004555361 3.931021e-03 4.194178e-02 16 29996808 29996860 53 + 1.591 1.438 -0.527
ENSG00000169592 E019 0.7423943 0.0132658387 9.053632e-01 9.697122e-01 16 29999270 29999568 299 + 0.238 0.219 -0.157
ENSG00000169592 E020 33.0934505 0.0004248014 1.193007e-05 3.981406e-04 16 30000758 30000836 79 + 1.641 1.414 -0.780
ENSG00000169592 E021 19.6000238 0.0007751173 1.225659e-06 5.564366e-05 16 30000929 30000970 42 + 1.475 1.155 -1.121
ENSG00000169592 E022 27.8873533 0.0012051865 3.368377e-06 1.334828e-04 16 30000971 30001040 70 + 1.591 1.326 -0.915
ENSG00000169592 E023 15.5238684 0.0009228160 6.275068e-03 5.832145e-02 16 30001212 30001413 202 + 1.006 1.236 0.828
ENSG00000169592 E024 22.0163719 0.0007220889 5.146882e-01 7.711405e-01 16 30001414 30001464 51 + 1.293 1.335 0.148
ENSG00000169592 E025 20.5009009 0.0012729210 8.387730e-01 9.421068e-01 16 30001465 30001530 66 + 1.285 1.298 0.045
ENSG00000169592 E026 50.2423316 0.0003088480 3.838012e-05 1.063717e-03 16 30001531 30002435 905 + 1.525 1.719 0.657
ENSG00000169592 E027 27.4774571 0.0012837739 1.752810e-06 7.599361e-05 16 30002436 30003013 578 + 1.162 1.489 1.141
ENSG00000169592 E028 7.0700084 0.0104359545 7.178969e-01 8.865073e-01 16 30003014 30003435 422 + 0.900 0.859 -0.157
ENSG00000169592 E029 12.0344361 0.0013068471 2.997516e-03 3.449286e-02 16 30003436 30003526 91 + 0.858 1.145 1.059
ENSG00000169592 E030 12.1076936 0.0011590286 1.096785e-01 3.475557e-01 16 30003527 30003649 123 + 0.973 1.118 0.529
ENSG00000169592 E031 6.8684542 0.0047029953 1.336176e-01 3.884293e-01 16 30003650 30003670 21 + 0.731 0.906 0.684
ENSG00000169592 E032 8.3919853 0.0047972712 1.684645e-02 1.131925e-01 16 30003671 30003714 44 + 0.731 1.001 1.039
ENSG00000169592 E033 52.1368437 0.0003323336 4.502655e-06 1.717441e-04 16 30003715 30004554 840 + 1.525 1.738 0.725
ENSG00000169592 E034 6.0463813 0.0095631610 1.015592e-03 1.518574e-02 16 30004555 30004567 13 + 0.451 0.906 1.947
ENSG00000169592 E035 15.4146337 0.0076174397 2.030975e-03 2.583663e-02 16 30004568 30004657 90 + 0.956 1.244 1.042
ENSG00000169592 E036 27.6973474 0.0005719195 2.507954e-02 1.457038e-01 16 30004658 30005220 563 + 1.317 1.455 0.480
ENSG00000169592 E037 28.7256002 0.0005094763 2.005891e-01 4.826704e-01 16 30005221 30005367 147 + 1.486 1.411 -0.259
ENSG00000169592 E038 36.5232519 0.0065690585 6.554146e-03 6.018922e-02 16 30005368 30005793 426 + 1.641 1.482 -0.543

Help

Please Click HERE to learn more details about the results from DEXseq.