ENSG00000169660

1 Isoform Switch

Summary Plot

Only the isoforms with fraction > 5% are shown below.

  • Note:

    • About the Coding Potential: Please check the spreadsheet in the “Results” tag to confirm the coding potential. The above figure only show the predicted coding potential. The “gene_biotype” in the result spreadsheet is from the database record. Therefore, if you find conflicts between “gene_biotype” and “codingPotential”, please trust the “gene_biotype”.

    • Notes on IDR and IDR_w_binding: As the prediction of Intrinsically Disordered Regions (IDR) and Intrinsically Disordered Binding Regions (IDBR) are done by two different tools we require two things to annotate the Intrinsically Disordered Binding Regions (IDBR). Firstly the IDBR (predicted by ANCHOR2) must be a region of at least 15 amino acids (after the smoothing). Secondly the fraction of the IDBR which overlaps the IDR predictions (done by IUPred3, again after smoothing) must be at least 80%. When that is the case the IDR type will be annotated as “IDR_w_binding_region” instead of just “IDR”. The current default parameters have not been rigorously tested and should be considered experimental.

    • For the function of any other domain, please Click HERE to search it through Pfam database.

Results

isoform_id gene_id condition_1 condition_2 gene_name gene_biotype iso_biotype gene_overall_mean gene_value_1 gene_value_2 gene_stderr_1 gene_stderr_2 gene_log2_fold_change iso_overall_mean iso_value_1 iso_value_2 iso_stderr_1 iso_stderr_2 iso_log2_fold_change IF_overall IF1 IF2 dIF isoform_switch_q_value gene_switch_q_value PTC codingPotential
ENST00000327949 ENSG00000169660 No_inf pgKDN_inf HEXD protein_coding protein_coding 12.04819 16.64097 9.021292 2.115584 0.7697384 -0.8826016 1.2996563 0.0000000 2.9740335 0.0000000 1.1875315 8.2211199 0.14090833 0.000000 0.330650 0.330650 0.01073505 0.01073505 FALSE TRUE
ENST00000337014 ENSG00000169660 No_inf pgKDN_inf HEXD protein_coding protein_coding 12.04819 16.64097 9.021292 2.115584 0.7697384 -0.8826016 2.2019780 3.0922739 1.5062384 0.5622354 0.9796379 -1.0328295 0.18595000 0.192450 0.174200 -0.018250 0.83258656 0.01073505 FALSE TRUE
ENST00000578616 ENSG00000169660 No_inf pgKDN_inf HEXD protein_coding nonsense_mediated_decay 12.04819 16.64097 9.021292 2.115584 0.7697384 -0.8826016 0.6151380 0.1602616 0.0000000 0.1602616 0.0000000 -4.0896815 0.05680000 0.011575 0.000000 -0.011575 0.93059082 0.01073505 FALSE TRUE
ENST00000582429 ENSG00000169660 No_inf pgKDN_inf HEXD protein_coding nonsense_mediated_decay 12.04819 16.64097 9.021292 2.115584 0.7697384 -0.8826016 0.9592952 1.5634481 0.5638150 0.9269363 0.5638150 -1.4552719 0.06922500 0.082375 0.056450 -0.025925 0.84913442 0.01073505 TRUE TRUE
ENST00000583354 ENSG00000169660 No_inf pgKDN_inf HEXD protein_coding nonsense_mediated_decay 12.04819 16.64097 9.021292 2.115584 0.7697384 -0.8826016 0.8300885 1.7323767 0.4474169 1.4226633 0.4474169 -1.9294750 0.05176667 0.080925 0.044975 -0.035950 0.87063602 0.01073505 FALSE FALSE
ENST00000583978 ENSG00000169660 No_inf pgKDN_inf HEXD protein_coding retained_intron 12.04819 16.64097 9.021292 2.115584 0.7697384 -0.8826016 1.4558619 2.0255134 0.9814664 0.4559961 0.3589971 -1.0377570 0.12319167 0.128825 0.111625 -0.017200 0.94694262 0.01073505   FALSE
ENST00000644886 ENSG00000169660 No_inf pgKDN_inf HEXD protein_coding retained_intron 12.04819 16.64097 9.021292 2.115584 0.7697384 -0.8826016 0.5765418 1.3909026 0.0000000 0.8041175 0.0000000 -7.1302129 0.03613333 0.076350 0.000000 -0.076350 0.59320943 0.01073505 FALSE TRUE
MSTRG.13527.10 ENSG00000169660 No_inf pgKDN_inf HEXD protein_coding   12.04819 16.64097 9.021292 2.115584 0.7697384 -0.8826016 1.9551513 2.9672985 1.4880412 1.3013365 0.5006547 -0.9909266 0.16997500 0.198925 0.174350 -0.024575 1.00000000 0.01073505 TRUE TRUE
  • Note:
    • The comparisons made can be identified as “from ‘condition_1’ to ‘condition_2’”, meaning ‘condition_1’ is considered the ground state and ‘condition_2’ the changed state. This also means that a positive dIF value indicates that the isoform usage is increased in ‘condition_2’ compared to ‘condition_1’. Since the ‘isoformFeatures’ entry is the most relevant part of the switchAnalyzeRlist object, the most-used standard methods have also been implemented to work directly on isoformFeatures.

Help

Please Click HERE to learn more details about the results of IsoformSwitchAnalyzeR.

2 Differential Exon Usage

Counts

All exons whithin this gene region are shown and numbering below.

Expression

All exons whithin this gene region are shown and numbering below.

Splicing

All exons whithin this gene region are shown and numbering below.

Transcripts

All isoforms whithin this gene region are shown below.

Results

groupID featureID exonBaseMean dispersion pvalue padj seqnames start end width strand pgKDN.inf No.inf log2fold_No.inf_pgKDN.inf
ENSG00000169660 E001 0.0000000       17 82418318 82418346 29 +      
ENSG00000169660 E002 0.4894115 0.016227405 0.558464059   17 82418347 82418660 314 + 0.219 0.135 -0.844
ENSG00000169660 E003 0.8616929 0.014821709 0.696690145 0.87616673 17 82418661 82418672 12 + 0.298 0.238 -0.429
ENSG00000169660 E004 1.3526125 0.225732965 0.685859456 0.87025700 17 82418673 82418686 14 + 0.422 0.321 -0.582
ENSG00000169660 E005 1.3526125 0.225732965 0.685859456 0.87025700 17 82418687 82418689 3 + 0.422 0.321 -0.582
ENSG00000169660 E006 1.4702431 0.105671651 0.392544843 0.67753180 17 82418690 82418696 7 + 0.472 0.321 -0.845
ENSG00000169660 E007 1.7236041 0.078451900 0.637771588 0.84546638 17 82418697 82418712 16 + 0.472 0.391 -0.430
ENSG00000169660 E008 1.7236041 0.078451900 0.637771588 0.84546638 17 82418713 82418715 3 + 0.472 0.391 -0.430
ENSG00000169660 E009 2.8380652 0.005474192 0.728149740 0.89158893 17 82418716 82418740 25 + 0.597 0.551 -0.207
ENSG00000169660 E010 5.3858182 0.002997371 0.050370091 0.22176820 17 82419749 82419799 51 + 0.915 0.701 -0.844
ENSG00000169660 E011 7.2553921 0.002137793 0.176180509 0.45032355 17 82419800 82419883 84 + 0.979 0.847 -0.500
ENSG00000169660 E012 3.6010125 0.005210605 0.606657123 0.82883965 17 82419884 82420422 539 + 0.597 0.668 0.308
ENSG00000169660 E013 0.8707590 0.051519787 0.712134278 0.88376093 17 82423310 82423599 290 + 0.219 0.282 0.478
ENSG00000169660 E014 3.3398170 0.060828084 0.849577289 0.94648231 17 82424394 82424418 25 + 0.631 0.613 -0.078
ENSG00000169660 E015 5.4211669 0.185455619 0.603066621 0.82686115 17 82424419 82424503 85 + 0.839 0.760 -0.311
ENSG00000169660 E016 0.7522469 0.013826580 0.316920767 0.60970533 17 82428030 82428127 98 + 0.123 0.282 1.478
ENSG00000169660 E017 1.5959973 0.076228627 0.487271681 0.75082883 17 82428558 82428562 5 + 0.472 0.358 -0.621
ENSG00000169660 E018 4.9590732 0.002935698 0.679352774 0.86752886 17 82428563 82428645 83 + 0.721 0.773 0.210
ENSG00000169660 E019 7.4003109 0.002086729 0.474908525 0.74156677 17 82433658 82433799 142 + 0.948 0.879 -0.259
ENSG00000169660 E020 3.3310650 0.004474213 0.579624825 0.81231138 17 82433800 82433822 23 + 0.663 0.594 -0.304
ENSG00000169660 E021 9.4858255 0.003626152 0.278449176 0.57168752 17 82435689 82435872 184 + 1.060 0.965 -0.352
ENSG00000169660 E022 6.9282761 0.023076817 0.952602609 0.98825179 17 82436667 82436728 62 + 0.878 0.879 0.004
ENSG00000169660 E023 4.7343276 0.018130281 0.254741568 0.54655230 17 82436729 82436738 10 + 0.631 0.786 0.641
ENSG00000169660 E024 8.3985630 0.001773124 0.001237341 0.01764070 17 82436739 82437126 388 + 0.693 1.043 1.352
ENSG00000169660 E025 1.6505716 0.009667919 0.001733119 0.02284870 17 82437127 82437167 41 + 0.000 0.528 11.696
ENSG00000169660 E026 4.8331357 0.004293653 0.768861479 0.91062684 17 82437168 82437214 47 + 0.721 0.760 0.156
ENSG00000169660 E027 8.3081575 0.001682481 0.003104344 0.03538991 17 82437215 82437363 149 + 1.107 0.835 -1.014
ENSG00000169660 E028 6.2833608 0.002314852 0.407455512 0.68998215 17 82439631 82439713 83 + 0.897 0.812 -0.330
ENSG00000169660 E029 7.7460030 0.002184379 0.025126551 0.14579617 17 82439714 82439999 286 + 0.748 0.990 0.933
ENSG00000169660 E030 4.2167075 0.003549773 0.689492375 0.87238327 17 82440000 82440113 114 + 0.663 0.716 0.220
ENSG00000169660 E031 6.2542229 0.002325046 0.091299601 0.31388021 17 82440114 82440262 149 + 0.948 0.773 -0.674
ENSG00000169660 E032 4.8405236 0.017870538 0.547208602 0.79270363 17 82440263 82440334 72 + 0.693 0.773 0.326
ENSG00000169660 E033 4.4992076 0.013814185 0.095419868 0.32159593 17 82440335 82440472 138 + 0.559 0.786 0.963
ENSG00000169660 E034 5.2509482 0.002796790 0.045090626 0.20766099 17 82440473 82440613 141 + 0.597 0.847 1.030
ENSG00000169660 E035 1.1158775 0.263075800 0.918814977 0.97439961 17 82440997 82441070 74 + 0.298 0.321 0.156
ENSG00000169660 E036 1.4869978 0.282536974 0.916306378 0.97370772 17 82441071 82441075 5 + 0.364 0.391 0.156
ENSG00000169660 E037 1.3514255 0.376993846 0.638863915 0.84638876 17 82441076 82441152 77 + 0.422 0.321 -0.581
ENSG00000169660 E038 1.1157184 0.288038613 0.959822127 0.99071895 17 82441153 82441164 12 + 0.298 0.321 0.155
ENSG00000169660 E039 8.3257022 0.002025206 0.313133026 0.60640741 17 82441165 82441266 102 + 0.878 0.982 0.389
ENSG00000169660 E040 6.1980760 0.002550931 0.814109219 0.93207452 17 82441800 82441820 21 + 0.818 0.847 0.113
ENSG00000169660 E041 5.3364170 0.002847639 0.676635339 0.86596864 17 82441821 82441889 69 + 0.748 0.799 0.206
ENSG00000169660 E042 0.0000000       17 82442177 82442645 469 +      

Help

Please Click HERE to learn more details about the results from DEXseq.