ENSG00000169696

1 Isoform Switch

Summary Plot

Only the isoforms with fraction > 5% are shown below.

  • Note:

    • About the Coding Potential: Please check the spreadsheet in the “Results” tag to confirm the coding potential. The above figure only show the predicted coding potential. The “gene_biotype” in the result spreadsheet is from the database record. Therefore, if you find conflicts between “gene_biotype” and “codingPotential”, please trust the “gene_biotype”.

    • Notes on IDR and IDR_w_binding: As the prediction of Intrinsically Disordered Regions (IDR) and Intrinsically Disordered Binding Regions (IDBR) are done by two different tools we require two things to annotate the Intrinsically Disordered Binding Regions (IDBR). Firstly the IDBR (predicted by ANCHOR2) must be a region of at least 15 amino acids (after the smoothing). Secondly the fraction of the IDBR which overlaps the IDR predictions (done by IUPred3, again after smoothing) must be at least 80%. When that is the case the IDR type will be annotated as “IDR_w_binding_region” instead of just “IDR”. The current default parameters have not been rigorously tested and should be considered experimental.

    • For the function of any other domain, please Click HERE to search it through Pfam database.

Results

isoform_id gene_id condition_1 condition_2 gene_name gene_biotype iso_biotype gene_overall_mean gene_value_1 gene_value_2 gene_stderr_1 gene_stderr_2 gene_log2_fold_change iso_overall_mean iso_value_1 iso_value_2 iso_stderr_1 iso_stderr_2 iso_log2_fold_change IF_overall IF1 IF2 dIF isoform_switch_q_value gene_switch_q_value PTC codingPotential
ENST00000306739 ENSG00000169696 No_inf pgKDN_inf ASPSCR1 protein_coding protein_coding 22.75644 27.6694 19.00788 1.90785 0.70833 -0.5414563 5.837670 3.385205 6.8985945 2.0521507 2.3785289 1.02489338 0.27296667 0.129125 0.361225 0.232100 6.303899e-01 4.279168e-05 FALSE TRUE
ENST00000581647 ENSG00000169696 No_inf pgKDN_inf ASPSCR1 protein_coding protein_coding 22.75644 27.6694 19.00788 1.90785 0.70833 -0.5414563 1.652911 1.526631 1.1689995 0.4672812 0.9048228 -0.38220771 0.07203333 0.054150 0.061650 0.007500 8.404370e-01 4.279168e-05 FALSE TRUE
ENST00000582019 ENSG00000169696 No_inf pgKDN_inf ASPSCR1 protein_coding protein_coding 22.75644 27.6694 19.00788 1.90785 0.70833 -0.5414563 1.315598 2.622954 0.6680688 0.1503377 0.2333733 -1.95717868 0.05389167 0.095425 0.035725 -0.059700 4.078347e-01 4.279168e-05   FALSE
ENST00000583503 ENSG00000169696 No_inf pgKDN_inf ASPSCR1 protein_coding nonsense_mediated_decay 22.75644 27.6694 19.00788 1.90785 0.70833 -0.5414563 1.149258 3.095954 0.0000000 0.2230295 0.0000000 -8.27889282 0.04354167 0.113725 0.000000 -0.113725 4.279168e-05 4.279168e-05 TRUE TRUE
ENST00000583693 ENSG00000169696 No_inf pgKDN_inf ASPSCR1 protein_coding retained_intron 22.75644 27.6694 19.00788 1.90785 0.70833 -0.5414563 1.342228 2.136863 0.5967283 0.2005639 0.1416115 -1.82310778 0.05629167 0.078375 0.031225 -0.047150 5.051283e-01 4.279168e-05 TRUE TRUE
ENST00000583744 ENSG00000169696 No_inf pgKDN_inf ASPSCR1 protein_coding protein_coding 22.75644 27.6694 19.00788 1.90785 0.70833 -0.5414563 2.205912 3.337437 3.2802997 2.4435155 1.8952302 -0.02483791 0.09098333 0.109675 0.163275 0.053600 9.599005e-01 4.279168e-05 FALSE FALSE
MSTRG.13487.3 ENSG00000169696 No_inf pgKDN_inf ASPSCR1 protein_coding   22.75644 27.6694 19.00788 1.90785 0.70833 -0.5414563 1.587287 0.000000 2.6372900 0.0000000 1.9061727 8.04837245 0.08019167 0.000000 0.143900 0.143900 4.414246e-01 4.279168e-05 TRUE TRUE
MSTRG.13487.5 ENSG00000169696 No_inf pgKDN_inf ASPSCR1 protein_coding   22.75644 27.6694 19.00788 1.90785 0.70833 -0.5414563 3.340788 4.635075 1.3087344 1.7345540 0.8909501 -1.81654774 0.14756667 0.171700 0.073250 -0.098450 7.384263e-01 4.279168e-05 TRUE TRUE
  • Note:
    • The comparisons made can be identified as “from ‘condition_1’ to ‘condition_2’”, meaning ‘condition_1’ is considered the ground state and ‘condition_2’ the changed state. This also means that a positive dIF value indicates that the isoform usage is increased in ‘condition_2’ compared to ‘condition_1’. Since the ‘isoformFeatures’ entry is the most relevant part of the switchAnalyzeRlist object, the most-used standard methods have also been implemented to work directly on isoformFeatures.

Help

Please Click HERE to learn more details about the results of IsoformSwitchAnalyzeR.

2 Differential Exon Usage

Counts

All exons whithin this gene region are shown and numbering below.

Expression

All exons whithin this gene region are shown and numbering below.

Splicing

All exons whithin this gene region are shown and numbering below.

Transcripts

All isoforms whithin this gene region are shown below.

Results

groupID featureID exonBaseMean dispersion pvalue padj seqnames start end width strand pgKDN.inf No.inf log2fold_No.inf_pgKDN.inf
ENSG00000169696 E001 0.0000000       17 81976807 81976979 173 +      
ENSG00000169696 E002 0.1271363 0.012412464 8.466721e-01   17 81977550 81977580 31 + 0.000 0.078 9.183
ENSG00000169696 E003 0.2458395 0.016644540 7.365779e-01   17 81977581 81977601 21 + 0.115 0.078 -0.621
ENSG00000169696 E004 0.4918050 0.152455428 6.918258e-01   17 81977602 81977624 23 + 0.206 0.144 -0.622
ENSG00000169696 E005 0.6183120 0.026077351 9.747538e-01 9.954114e-01 17 81977625 81977628 4 + 0.206 0.202 -0.036
ENSG00000169696 E006 0.6183120 0.026077351 9.747538e-01 9.954114e-01 17 81977629 81977630 2 + 0.206 0.202 -0.036
ENSG00000169696 E007 0.6183120 0.026077351 9.747538e-01 9.954114e-01 17 81977631 81977633 3 + 0.206 0.202 -0.036
ENSG00000169696 E008 1.6917594 0.010572379 1.670243e-02 1.126881e-01 17 81977634 81977640 7 + 0.606 0.253 -1.943
ENSG00000169696 E009 6.7376288 0.028781448 1.367280e-01 3.935262e-01 17 81977641 81977704 64 + 0.978 0.801 -0.674
ENSG00000169696 E010 7.1168353 0.009059226 1.861259e-01 4.639953e-01 17 81977705 81977748 44 + 0.978 0.840 -0.522
ENSG00000169696 E011 1.4853600 0.190821261 7.032165e-01 8.792148e-01 17 81977899 81978185 287 + 0.345 0.411 0.380
ENSG00000169696 E012 1.4947984 0.008988818 2.970950e-01 5.903331e-01 17 81978186 81978339 154 + 0.281 0.443 0.964
ENSG00000169696 E013 2.3855724 0.006624294 2.631075e-02 1.502906e-01 17 81978340 81978804 465 + 0.281 0.619 1.794
ENSG00000169696 E014 7.2209302 0.028579015 8.600136e-02 3.037191e-01 17 81979184 81979239 56 + 1.018 0.815 -0.769
ENSG00000169696 E015 0.1271363 0.012412464 8.466721e-01   17 81982614 81982676 63 + 0.000 0.078 9.187
ENSG00000169696 E016 13.5232571 0.046380105 3.630979e-01 6.521734e-01 17 81983554 81983668 115 + 1.217 1.102 -0.413
ENSG00000169696 E017 12.8863788 0.001774059 8.652468e-02 3.048287e-01 17 81985507 81985607 101 + 1.209 1.074 -0.484
ENSG00000169696 E018 6.4891793 0.003557994 1.572780e-01 4.238542e-01 17 81994821 81994878 58 + 0.949 0.801 -0.567
ENSG00000169696 E019 0.4996734 0.048052921 5.752931e-01   17 81994879 81994957 79 + 0.115 0.202 0.964
ENSG00000169696 E020 0.9996906 0.017605634 3.988567e-01 6.826930e-01 17 81994958 81995150 193 + 0.206 0.339 0.964
ENSG00000169696 E021 0.0000000       17 81995443 81995548 106 +      
ENSG00000169696 E022 8.2140501 0.004893828 1.741833e-01 4.478217e-01 17 81995992 81996065 74 + 1.030 0.898 -0.492
ENSG00000169696 E023 24.5424774 0.007110049 3.376174e-02 1.748685e-01 17 81996420 81996846 427 + 1.475 1.337 -0.477
ENSG00000169696 E024 6.7925188 0.002241672 1.794038e-05 5.628834e-04 17 82004345 82006641 2297 + 0.495 1.012 2.126
ENSG00000169696 E025 2.1381299 0.099631559 3.335924e-02 1.736509e-01 17 82006642 82007434 793 + 0.206 0.598 2.285
ENSG00000169696 E026 6.0745146 0.014601498 4.120371e-08 2.611376e-06 17 82007435 82009036 1602 + 0.206 1.003 3.902
ENSG00000169696 E027 14.6290492 0.001125534 1.012156e-01 3.322516e-01 17 82009037 82009184 148 + 1.098 1.225 0.453
ENSG00000169696 E028 6.5725968 0.002422077 2.712395e-01 5.649583e-01 17 82009185 82009191 7 + 0.790 0.909 0.461
ENSG00000169696 E029 10.2804748 0.001535715 2.853026e-01 5.790002e-01 17 82009486 82009567 82 + 0.978 1.074 0.353
ENSG00000169696 E030 0.0000000       17 82009932 82010052 121 +      
ENSG00000169696 E031 4.3395677 0.003461946 3.308734e-01 6.231525e-01 17 82010802 82010810 9 + 0.637 0.759 0.504
ENSG00000169696 E032 9.0919058 0.001584716 3.608080e-01 6.503794e-01 17 82010811 82010868 58 + 1.042 0.959 -0.308
ENSG00000169696 E033 12.4053098 0.001541177 2.054408e-01 4.886662e-01 17 82011543 82011605 63 + 1.175 1.074 -0.364
ENSG00000169696 E034 0.0000000       17 82012084 82012155 72 +      
ENSG00000169696 E035 0.9877327 0.175179007 9.226173e-01 9.761735e-01 17 82012156 82012230 75 + 0.281 0.298 0.116
ENSG00000169696 E036 13.7043224 0.011183163 2.449455e-02 1.436435e-01 17 82012231 82012283 53 + 1.263 1.074 -0.673
ENSG00000169696 E037 1.4814249 0.340475495 8.509752e-01 9.472419e-01 17 82012882 82013050 169 + 0.401 0.377 -0.139
ENSG00000169696 E038 10.9195356 0.008681516 2.346397e-06 9.719707e-05 17 82013234 82015074 1841 + 0.694 1.193 1.888
ENSG00000169696 E039 1.6250809 0.008766822 2.173601e-01 5.037703e-01 17 82015075 82015213 139 + 0.281 0.473 1.116
ENSG00000169696 E040 1.9941562 0.007828973 2.299694e-01 5.184839e-01 17 82015214 82015356 143 + 0.345 0.527 0.964
ENSG00000169696 E041 9.1363504 0.001943704 2.046701e-04 4.268629e-03 17 82015357 82016193 837 + 0.720 1.102 1.454
ENSG00000169696 E042 1.8771810 0.007387621 1.100991e-01 3.481930e-01 17 82016194 82016308 115 + 0.281 0.527 1.379
ENSG00000169696 E043 2.4763266 0.017568003 6.848744e-01 8.696413e-01 17 82016309 82016475 167 + 0.495 0.552 0.272
ENSG00000169696 E044 13.0703585 0.004553330 8.458035e-03 7.181606e-02 17 82016476 82016527 52 + 1.255 1.044 -0.756
ENSG00000169696 E045 3.9839019 0.036883062 2.378459e-01 5.268563e-01 17 82016528 82016799 272 + 0.572 0.744 0.733
ENSG00000169696 E046 13.1473949 0.001236852 2.445300e-01 5.348344e-01 17 82016800 82016869 70 + 1.192 1.102 -0.324
ENSG00000169696 E047 2.3661543 0.006030728 2.349544e-01 5.240953e-01 17 82016870 82016940 71 + 0.401 0.576 0.864
ENSG00000169696 E048 13.8948284 0.006066442 4.080910e-01 6.904876e-01 17 82016941 82017088 148 + 1.201 1.134 -0.236
ENSG00000169696 E049 4.5506621 0.003114976 6.340907e-01 8.436261e-01 17 82017089 82017113 25 + 0.768 0.711 -0.229
ENSG00000169696 E050 0.1272623 0.012384052 8.467121e-01   17 82017114 82017133 20 + 0.000 0.078 9.187
ENSG00000169696 E051 4.9391828 0.004599372 8.039746e-01 9.271830e-01 17 82017309 82017406 98 + 0.745 0.773 0.116

Help

Please Click HERE to learn more details about the results from DEXseq.