ENSG00000169710

1 Isoform Switch

Summary Plot

Only the isoforms with fraction > 5% are shown below.

  • Note:

    • About the Coding Potential: Please check the spreadsheet in the “Results” tag to confirm the coding potential. The above figure only show the predicted coding potential. The “gene_biotype” in the result spreadsheet is from the database record. Therefore, if you find conflicts between “gene_biotype” and “codingPotential”, please trust the “gene_biotype”.

    • Notes on IDR and IDR_w_binding: As the prediction of Intrinsically Disordered Regions (IDR) and Intrinsically Disordered Binding Regions (IDBR) are done by two different tools we require two things to annotate the Intrinsically Disordered Binding Regions (IDBR). Firstly the IDBR (predicted by ANCHOR2) must be a region of at least 15 amino acids (after the smoothing). Secondly the fraction of the IDBR which overlaps the IDR predictions (done by IUPred3, again after smoothing) must be at least 80%. When that is the case the IDR type will be annotated as “IDR_w_binding_region” instead of just “IDR”. The current default parameters have not been rigorously tested and should be considered experimental.

    • For the function of any other domain, please Click HERE to search it through Pfam database.

Results

isoform_id gene_id condition_1 condition_2 gene_name gene_biotype iso_biotype gene_overall_mean gene_value_1 gene_value_2 gene_stderr_1 gene_stderr_2 gene_log2_fold_change iso_overall_mean iso_value_1 iso_value_2 iso_stderr_1 iso_stderr_2 iso_log2_fold_change IF_overall IF1 IF2 dIF isoform_switch_q_value gene_switch_q_value PTC codingPotential
ENST00000306749 ENSG00000169710 No_inf pgKDN_inf FASN protein_coding protein_coding 88.1058 53.3119 95.02108 4.208253 1.5716 0.8336711 34.428975 13.634350 47.058350 5.693819 4.467436 1.7864537 0.3797167 0.264050 0.495625 0.231575 0.712238574 0.003143513 FALSE TRUE
ENST00000578424 ENSG00000169710 No_inf pgKDN_inf FASN protein_coding retained_intron 88.1058 53.3119 95.02108 4.208253 1.5716 0.8336711 8.810263 3.047281 9.227089 2.340765 4.501396 1.5951894 0.0957000 0.061050 0.099525 0.038475 0.808998498 0.003143513 FALSE TRUE
ENST00000580382 ENSG00000169710 No_inf pgKDN_inf FASN protein_coding nonsense_mediated_decay 88.1058 53.3119 95.02108 4.208253 1.5716 0.8336711 11.446363 6.800927 13.842412 2.562936 5.017057 1.0242141 0.1249500 0.123075 0.143225 0.020150 1.000000000 0.003143513 FALSE TRUE
MSTRG.13490.1 ENSG00000169710 No_inf pgKDN_inf FASN protein_coding   88.1058 53.3119 95.02108 4.208253 1.5716 0.8336711 10.540859 8.501895 7.853319 5.306967 4.610862 -0.1143420 0.1219167 0.159950 0.082550 -0.077400 1.000000000 0.003143513 FALSE TRUE
MSTRG.13490.3 ENSG00000169710 No_inf pgKDN_inf FASN protein_coding   88.1058 53.3119 95.02108 4.208253 1.5716 0.8336711 19.523694 18.164439 16.457536 1.197605 1.114462 -0.1422861 0.2417917 0.342000 0.172850 -0.169150 0.003143513 0.003143513 TRUE TRUE
  • Note:
    • The comparisons made can be identified as “from ‘condition_1’ to ‘condition_2’”, meaning ‘condition_1’ is considered the ground state and ‘condition_2’ the changed state. This also means that a positive dIF value indicates that the isoform usage is increased in ‘condition_2’ compared to ‘condition_1’. Since the ‘isoformFeatures’ entry is the most relevant part of the switchAnalyzeRlist object, the most-used standard methods have also been implemented to work directly on isoformFeatures.

Help

Please Click HERE to learn more details about the results of IsoformSwitchAnalyzeR.

2 Differential Exon Usage

Counts

All exons whithin this gene region are shown and numbering below.

Expression

All exons whithin this gene region are shown and numbering below.

Splicing

All exons whithin this gene region are shown and numbering below.

Transcripts

All isoforms whithin this gene region are shown below.

Results

groupID featureID exonBaseMean dispersion pvalue padj seqnames start end width strand pgKDN.inf No.inf log2fold_No.inf_pgKDN.inf
ENSG00000169710 E001 2.3108889 0.0093967591 4.717929e-01 7.390792e-01 17 82078338 82078339 2 - 0.467 0.572 0.502
ENSG00000169710 E002 272.0816283 0.0005663991 5.143867e-06 1.926593e-04 17 82078340 82078996 657 - 2.382 2.475 0.309
ENSG00000169710 E003 26.0223825 0.0034590137 7.724842e-04 1.230090e-02 17 82078997 82079006 10 - 1.326 1.537 0.730
ENSG00000169710 E004 76.1323768 0.0001999090 1.073674e-03 1.580878e-02 17 82079007 82079167 161 - 1.824 1.940 0.391
ENSG00000169710 E005 61.8578269 0.0002490139 1.227232e-01 3.707889e-01 17 82079168 82079221 54 - 1.757 1.819 0.209
ENSG00000169710 E006 63.2949454 0.0002551639 2.131931e-01 4.984116e-01 17 82079222 82079280 59 - 1.771 1.821 0.168
ENSG00000169710 E007 0.2441403 0.0164392504 6.050978e-01   17 82079281 82079299 19 - 0.070 0.128 0.961
ENSG00000169710 E008 150.2325100 0.0001209733 5.265582e-04 9.087805e-03 17 82079357 82079608 252 - 2.128 2.215 0.294
ENSG00000169710 E009 9.4452965 0.0139340153 4.169411e-09 3.171693e-07 17 82079609 82080015 407 - 0.687 1.289 2.256
ENSG00000169710 E010 64.0664231 0.0009331572 6.939845e-03 6.272108e-02 17 82080140 82080238 99 - 1.753 1.862 0.367
ENSG00000169710 E011 73.4996771 0.0002074458 4.583830e-01 7.303093e-01 17 82080370 82080535 166 - 1.863 1.836 -0.089
ENSG00000169710 E012 39.1987113 0.0003542901 8.049649e-01 9.278227e-01 17 82080536 82080590 55 - 1.590 1.578 -0.039
ENSG00000169710 E013 0.8467118 0.0132782778 7.609470e-01 9.065609e-01 17 82080591 82080691 101 - 0.274 0.226 -0.361
ENSG00000169710 E014 98.7704263 0.0001601628 9.801295e-01 9.977408e-01 17 82080692 82080922 231 - 1.980 1.980 0.001
ENSG00000169710 E015 0.4975013 0.0152804263 9.842474e-02   17 82080923 82080938 16 - 0.070 0.306 2.546
ENSG00000169710 E016 76.8243574 0.0002328082 4.776860e-01 7.439006e-01 17 82081164 82081352 189 - 1.863 1.889 0.089
ENSG00000169710 E017 96.9319493 0.0010238804 3.614030e-01 6.508367e-01 17 82081601 82081843 243 - 1.961 1.993 0.107
ENSG00000169710 E018 72.9788194 0.0043223688 9.063020e-01 9.701205e-01 17 82082009 82082160 152 - 1.852 1.847 -0.018
ENSG00000169710 E019 47.6667433 0.0024027398 8.966691e-02 3.111291e-01 17 82082323 82082414 92 - 1.697 1.612 -0.288
ENSG00000169710 E020 81.5265558 0.0001912521 5.439631e-03 5.260554e-02 17 82082527 82082678 152 - 1.930 1.832 -0.331
ENSG00000169710 E021 100.8115929 0.0001814087 2.550374e-01 5.469694e-01 17 82082914 82083115 202 - 2.001 1.966 -0.118
ENSG00000169710 E022 87.1754885 0.0004391435 4.344224e-01 7.117080e-01 17 82083202 82083425 224 - 1.936 1.910 -0.087
ENSG00000169710 E023 49.7607945 0.0062017579 9.129872e-01 9.723616e-01 17 82083517 82083639 123 - 1.685 1.692 0.024
ENSG00000169710 E024 38.3437689 0.0012082687 4.721993e-02 2.134745e-01 17 82083772 82083891 120 - 1.611 1.506 -0.358
ENSG00000169710 E025 12.6221645 0.0269458475 7.189398e-02 2.719866e-01 17 82083975 82083978 4 - 1.177 0.979 -0.718
ENSG00000169710 E026 43.6139675 0.0003582359 9.741303e-03 7.895814e-02 17 82083979 82084153 175 - 1.672 1.546 -0.429
ENSG00000169710 E027 54.8230783 0.0002679478 1.544134e-01 4.198327e-01 17 82084234 82084384 151 - 1.749 1.689 -0.204
ENSG00000169710 E028 71.6563140 0.0046514874 9.166204e-01 9.737743e-01 17 82084513 82084716 204 - 1.840 1.847 0.023
ENSG00000169710 E029 46.5088655 0.0003525343 3.410263e-01 6.326443e-01 17 82084799 82084953 155 - 1.673 1.630 -0.147
ENSG00000169710 E030 40.0435924 0.0041435926 1.281088e-01 3.793882e-01 17 82085035 82085156 122 - 1.624 1.537 -0.295
ENSG00000169710 E031 0.1186381 0.0118483773 1.000000e+00   17 82085158 82085237 80 - 0.070 0.000 -11.379
ENSG00000169710 E032 46.0149153 0.0003551513 2.567047e-01 5.488212e-01 17 82085238 82085402 165 - 1.672 1.620 -0.178
ENSG00000169710 E033 81.1630238 0.0001895520 1.114063e-01 3.505146e-01 17 82085482 82085871 390 - 1.915 1.860 -0.186
ENSG00000169710 E034 12.6663557 0.0190116442 3.385217e-01 6.302323e-01 17 82086254 82086259 6 - 1.151 1.051 -0.361
ENSG00000169710 E035 31.7197145 0.0119940114 9.127580e-01 9.722975e-01 17 82086260 82086425 166 - 1.499 1.492 -0.023
ENSG00000169710 E036 27.0672759 0.0005122598 4.707186e-01 7.383197e-01 17 82086426 82086558 133 - 1.445 1.402 -0.147
ENSG00000169710 E037 40.4702087 0.0003474307 6.755662e-03 6.158889e-02 17 82087050 82087253 204 - 1.643 1.506 -0.468
ENSG00000169710 E038 40.6985042 0.0082066909 2.907323e-01 5.842595e-01 17 82087325 82087504 180 - 1.624 1.558 -0.223
ENSG00000169710 E039 33.9489092 0.0018284936 4.345159e-01 7.117749e-01 17 82087685 82087861 177 - 1.540 1.497 -0.148
ENSG00000169710 E040 23.0117400 0.0006622120 8.280802e-01 9.377386e-01 17 82087954 82088034 81 - 1.357 1.372 0.051
ENSG00000169710 E041 41.5541388 0.0003709886 3.684755e-01 6.569923e-01 17 82088116 82088307 192 - 1.626 1.582 -0.147
ENSG00000169710 E042 38.6068946 0.0003588924 1.305330e-01 3.832730e-01 17 82088390 82088562 173 - 1.605 1.529 -0.261
ENSG00000169710 E043 29.9552889 0.0004737903 4.005672e-01 6.839551e-01 17 82088761 82088876 116 - 1.489 1.441 -0.163
ENSG00000169710 E044 47.8485827 0.0002910027 3.081548e-01 6.013468e-01 17 82088969 82089172 204 - 1.686 1.640 -0.155
ENSG00000169710 E045 30.7735626 0.0004993662 5.407677e-01 7.886342e-01 17 82089250 82089384 135 - 1.471 1.506 0.120
ENSG00000169710 E046 19.3577266 0.0153338746 4.487909e-02 2.070791e-01 17 82089632 82089726 95 - 1.225 1.390 0.578
ENSG00000169710 E047 27.9248023 0.0005265287 7.298759e-01 8.924511e-01 17 82090375 82090564 190 - 1.450 1.431 -0.067
ENSG00000169710 E048 12.6442542 0.0014167089 1.669787e-01 4.374096e-01 17 82090882 82090902 21 - 1.156 1.038 -0.429
ENSG00000169710 E049 30.4544796 0.0072129723 5.212265e-01 7.753053e-01 17 82090903 82091069 167 - 1.494 1.452 -0.143
ENSG00000169710 E050 50.3937554 0.0091050910 7.778354e-02 2.853862e-01 17 82091222 82091684 463 - 1.727 1.623 -0.351
ENSG00000169710 E051 25.6165078 0.0005784211 4.652213e-01 7.343707e-01 17 82092455 82092589 135 - 1.422 1.378 -0.153
ENSG00000169710 E052 26.0795360 0.0005035271 2.861020e-01 5.797614e-01 17 82092697 82092812 116 - 1.436 1.372 -0.223
ENSG00000169710 E053 23.4756314 0.0006017200 4.255995e-02 2.010535e-01 17 82092897 82093019 123 - 1.413 1.281 -0.461
ENSG00000169710 E054 22.7770930 0.0067476710 8.849526e-02 3.086207e-01 17 82093219 82093419 201 - 1.399 1.273 -0.437
ENSG00000169710 E055 8.3665000 0.0016644850 6.984456e-01 8.770247e-01 17 82093598 82093600 3 - 0.940 0.979 0.145
ENSG00000169710 E056 21.9743566 0.0007456883 4.494685e-01 7.231560e-01 17 82093601 82093771 171 - 1.360 1.311 -0.172
ENSG00000169710 E057 2.3219009 0.0085461785 2.376266e-01 5.265732e-01 17 82093772 82094103 332 - 0.440 0.610 0.809
ENSG00000169710 E058 1.7238895 0.2205500543 2.667982e-01 5.601987e-01 17 82094104 82094187 84 - 0.312 0.572 1.377
ENSG00000169710 E059 21.7299201 0.0019377074 3.442980e-01 6.356108e-01 17 82095320 82095472 153 - 1.360 1.296 -0.223
ENSG00000169710 E060 12.3640133 0.0212314008 6.925990e-01 8.741897e-01 17 82096319 82096389 71 - 1.093 1.135 0.148
ENSG00000169710 E061 6.1949828 0.0171126189 4.813192e-01 7.464123e-01 17 82096390 82096402 13 - 0.809 0.894 0.329
ENSG00000169710 E062 6.3024187 0.0182562403 7.340860e-01 8.944097e-01 17 82096403 82096414 12 - 0.832 0.874 0.165
ENSG00000169710 E063 6.2939539 0.0024471845 9.255638e-01 9.776500e-01 17 82096415 82096447 33 - 0.843 0.854 0.044
ENSG00000169710 E064 1.9204177 0.0313728677 4.637015e-01 7.335242e-01 17 82096448 82096452 5 - 0.492 0.374 -0.624
ENSG00000169710 E065 0.0000000       17 82096453 82096478 26 -      
ENSG00000169710 E066 0.1271363 0.0123291465 2.639281e-01   17 82096787 82096802 16 - 0.000 0.128 11.842
ENSG00000169710 E067 0.1271363 0.0123291465 2.639281e-01   17 82096803 82096876 74 - 0.000 0.128 11.842
ENSG00000169710 E068 0.0000000       17 82097258 82097490 233 -      
ENSG00000169710 E069 0.1268540 0.0123950961 2.638198e-01   17 82097491 82097527 37 - 0.000 0.128 11.841
ENSG00000169710 E070 7.1260375 0.0029796595 7.754362e-01 9.137908e-01 17 82098121 82098294 174 - 0.904 0.874 -0.113

Help

Please Click HERE to learn more details about the results from DEXseq.