ENSG00000169718

1 Isoform Switch

Summary Plot

Only the isoforms with fraction > 5% are shown below.

  • Note:

    • About the Coding Potential: Please check the spreadsheet in the “Results” tag to confirm the coding potential. The above figure only show the predicted coding potential. The “gene_biotype” in the result spreadsheet is from the database record. Therefore, if you find conflicts between “gene_biotype” and “codingPotential”, please trust the “gene_biotype”.

    • Notes on IDR and IDR_w_binding: As the prediction of Intrinsically Disordered Regions (IDR) and Intrinsically Disordered Binding Regions (IDBR) are done by two different tools we require two things to annotate the Intrinsically Disordered Binding Regions (IDBR). Firstly the IDBR (predicted by ANCHOR2) must be a region of at least 15 amino acids (after the smoothing). Secondly the fraction of the IDBR which overlaps the IDR predictions (done by IUPred3, again after smoothing) must be at least 80%. When that is the case the IDR type will be annotated as “IDR_w_binding_region” instead of just “IDR”. The current default parameters have not been rigorously tested and should be considered experimental.

    • For the function of any other domain, please Click HERE to search it through Pfam database.

Results

isoform_id gene_id condition_1 condition_2 gene_name gene_biotype iso_biotype gene_overall_mean gene_value_1 gene_value_2 gene_stderr_1 gene_stderr_2 gene_log2_fold_change iso_overall_mean iso_value_1 iso_value_2 iso_stderr_1 iso_stderr_2 iso_log2_fold_change IF_overall IF1 IF2 dIF isoform_switch_q_value gene_switch_q_value PTC codingPotential
ENST00000538833 ENSG00000169718 No_inf pgKDN_inf DUS1L protein_coding protein_coding 96.81919 88.284 93.38648 2.484638 4.93305 0.08105288 21.271968 21.46107 16.027832 1.619512 1.358808 -0.4209151 0.2200167 0.244225 0.173500 -0.070725 0.511167740 0.006100744 FALSE TRUE
ENST00000542088 ENSG00000169718 No_inf pgKDN_inf DUS1L protein_coding protein_coding 96.81919 88.284 93.38648 2.484638 4.93305 0.08105288 9.702559 14.08413 5.191439 1.209399 0.549260 -1.4381115 0.1020583 0.160325 0.055575 -0.104750 0.006100744 0.006100744 FALSE TRUE
ENST00000579854 ENSG00000169718 No_inf pgKDN_inf DUS1L protein_coding retained_intron 96.81919 88.284 93.38648 2.484638 4.93305 0.08105288 21.858606 14.94879 28.312170 5.834881 3.214535 0.9209379 0.2234500 0.165875 0.300000 0.134125 0.660358479 0.006100744 FALSE FALSE
MSTRG.13493.7 ENSG00000169718 No_inf pgKDN_inf DUS1L protein_coding   96.81919 88.284 93.38648 2.484638 4.93305 0.08105288 27.406187 22.41940 26.126358 1.291544 5.947110 0.2206668 0.2815750 0.255525 0.279000 0.023475 0.977804951 0.006100744 FALSE TRUE
  • Note:
    • The comparisons made can be identified as “from ‘condition_1’ to ‘condition_2’”, meaning ‘condition_1’ is considered the ground state and ‘condition_2’ the changed state. This also means that a positive dIF value indicates that the isoform usage is increased in ‘condition_2’ compared to ‘condition_1’. Since the ‘isoformFeatures’ entry is the most relevant part of the switchAnalyzeRlist object, the most-used standard methods have also been implemented to work directly on isoformFeatures.

Help

Please Click HERE to learn more details about the results of IsoformSwitchAnalyzeR.

2 Differential Exon Usage

Counts

All exons whithin this gene region are shown and numbering below.

Expression

All exons whithin this gene region are shown and numbering below.

Splicing

All exons whithin this gene region are shown and numbering below.

Transcripts

All isoforms whithin this gene region are shown below.

Results

groupID featureID exonBaseMean dispersion pvalue padj seqnames start end width strand pgKDN.inf No.inf log2fold_No.inf_pgKDN.inf
ENSG00000169718 E001 0.2537079 0.2358381482 3.238350e-01   17 82057506 82057608 103 - 0.000 0.168 11.591
ENSG00000169718 E002 0.4899767 0.1069814309 9.291166e-01   17 82057609 82057871 263 - 0.179 0.168 -0.111
ENSG00000169718 E003 0.1176306 0.0118074081 4.963938e-01   17 82057872 82057879 8 - 0.098 0.000 -10.943
ENSG00000169718 E004 0.3646036 0.0165592606 5.348350e-01   17 82057880 82057881 2 - 0.179 0.092 -1.111
ENSG00000169718 E005 1.3432640 0.0162945627 6.680506e-01 8.618602e-01 17 82057882 82057901 20 - 0.402 0.338 -0.374
ENSG00000169718 E006 2.4694877 0.1496820151 6.449380e-01 8.496517e-01 17 82057902 82057904 3 - 0.482 0.583 0.474
ENSG00000169718 E007 4.6646322 0.0437791264 9.833152e-01 9.986903e-01 17 82057905 82057913 9 - 0.747 0.757 0.041
ENSG00000169718 E008 27.6311334 0.0014309535 8.018992e-01 9.261025e-01 17 82057914 82058015 102 - 1.447 1.463 0.056
ENSG00000169718 E009 37.7959675 0.0003828189 8.401325e-01 9.425882e-01 17 82058016 82058091 76 - 1.581 1.593 0.039
ENSG00000169718 E010 64.6589268 0.0002437667 8.010345e-01 9.257540e-01 17 82058092 82058254 163 - 1.810 1.821 0.037
ENSG00000169718 E011 50.1132646 0.0003299967 6.328755e-01 8.427775e-01 17 82058341 82058408 68 - 1.717 1.699 -0.061
ENSG00000169718 E012 30.0347129 0.0004730352 9.530677e-01 9.884336e-01 17 82058409 82058416 8 - 1.492 1.490 -0.005
ENSG00000169718 E013 9.6842348 0.0016914004 2.245286e-03 2.789617e-02 17 82058417 82058486 70 - 0.852 1.137 1.059
ENSG00000169718 E014 20.2857891 0.0007647629 2.962595e-07 1.552814e-05 17 82058487 82058780 294 - 1.104 1.456 1.236
ENSG00000169718 E015 46.8082663 0.0003823673 6.263031e-01 8.393870e-01 17 82058781 82058818 38 - 1.689 1.669 -0.065
ENSG00000169718 E016 19.6373829 0.0029028452 1.259323e-02 9.328431e-02 17 82058819 82059947 1129 - 1.211 1.386 0.612
ENSG00000169718 E017 77.2943275 0.0002171820 9.171935e-01 9.739953e-01 17 82059948 82060093 146 - 1.890 1.895 0.018
ENSG00000169718 E018 0.9819717 0.0542966481 9.061787e-01 9.700585e-01 17 82060094 82060157 64 - 0.305 0.288 -0.111
ENSG00000169718 E019 7.3129410 0.1549117253 1.583131e-01 4.252220e-01 17 82060158 82060700 543 - 0.766 1.018 0.963
ENSG00000169718 E020 45.4135076 0.0006181823 9.572711e-02 3.222194e-01 17 82060701 82060780 80 - 1.623 1.699 0.259
ENSG00000169718 E021 20.0893562 0.0006632154 6.055428e-01 8.280558e-01 17 82060781 82060783 3 - 1.340 1.308 -0.111
ENSG00000169718 E022 0.2459655 0.0163339510 9.497248e-01   17 82060784 82060860 77 - 0.098 0.092 -0.111
ENSG00000169718 E023 0.6336374 0.0400965374 2.784449e-02 1.558171e-01 17 82060861 82060864 4 - 0.000 0.338 12.938
ENSG00000169718 E024 20.8397156 0.0006634300 8.261378e-01 9.370213e-01 17 82060865 82060876 12 - 1.345 1.332 -0.043
ENSG00000169718 E025 37.5068587 0.0003797741 7.134268e-01 8.845101e-01 17 82060877 82060954 78 - 1.593 1.577 -0.054
ENSG00000169718 E026 19.8777495 0.0006827712 9.099398e-01 9.714619e-01 17 82060955 82060961 7 - 1.314 1.323 0.032
ENSG00000169718 E027 0.9969502 0.1299694997 2.507158e-01 5.418048e-01 17 82060962 82061208 247 - 0.179 0.383 1.474
ENSG00000169718 E028 34.3476203 0.0066121435 9.406506e-01 9.831865e-01 17 82061209 82061257 49 - 1.548 1.546 -0.008
ENSG00000169718 E029 47.2322333 0.0007886865 9.438846e-01 9.844702e-01 17 82061258 82061353 96 - 1.679 1.684 0.017
ENSG00000169718 E030 3.4799918 0.0731489133 8.628347e-02 3.043566e-01 17 82061354 82061556 203 - 0.482 0.757 1.212
ENSG00000169718 E031 3.0711067 0.0369511915 7.106981e-01 8.830578e-01 17 82061557 82061617 61 - 0.579 0.633 0.238
ENSG00000169718 E032 47.2390971 0.0015216104 7.194576e-01 8.868439e-01 17 82061618 82061721 104 - 1.672 1.691 0.062
ENSG00000169718 E033 46.6722448 0.0003360278 3.958916e-01 6.807860e-01 17 82061901 82061983 83 - 1.695 1.660 -0.118
ENSG00000169718 E034 31.4694183 0.0128682922 5.486292e-01 7.935791e-01 17 82062861 82062881 21 - 1.532 1.490 -0.144
ENSG00000169718 E035 28.2936771 0.0048051001 6.265504e-01 8.395329e-01 17 82062882 82062894 13 - 1.481 1.452 -0.098
ENSG00000169718 E036 46.5185075 0.0003413867 2.690428e-01 5.626367e-01 17 82062895 82062973 79 - 1.700 1.654 -0.156
ENSG00000169718 E037 1.7327993 0.0473500309 3.907507e-01 6.761266e-01 17 82062974 82063467 494 - 0.356 0.494 0.737
ENSG00000169718 E038 29.3112652 0.0043278639 8.726975e-01 9.565454e-01 17 82063468 82063518 51 - 1.484 1.477 -0.026
ENSG00000169718 E039 35.5221661 0.0004062833 4.883882e-01 7.517117e-01 17 82064126 82064201 76 - 1.578 1.546 -0.111
ENSG00000169718 E040 25.2018507 0.0005666692 2.561573e-03 3.066565e-02 17 82064202 82064234 33 - 1.502 1.328 -0.603
ENSG00000169718 E041 0.4719109 0.0159225641 3.725945e-02   17 82064235 82064327 93 - 0.305 0.000 -12.943
ENSG00000169718 E042 51.6385282 0.0002918815 7.718698e-03 6.747168e-02 17 82064823 82065069 247 - 1.774 1.667 -0.364
ENSG00000169718 E043 0.6248897 0.0146861396 2.026898e-01 4.851963e-01 17 82065070 82065545 476 - 0.098 0.288 1.889
ENSG00000169718 E044 19.6573178 0.0007002145 1.250799e-01 3.749143e-01 17 82065613 82065887 275 - 1.364 1.266 -0.344
ENSG00000169718 E045 0.3809703 0.0258477443 1.213369e-01   17 82066179 82066242 64 - 0.000 0.232 12.202

Help

Please Click HERE to learn more details about the results from DEXseq.