ENSG00000169756

1 Isoform Switch

Summary Plot

Only the isoforms with fraction > 5% are shown below.

  • Note:

    • About the Coding Potential: Please check the spreadsheet in the “Results” tag to confirm the coding potential. The above figure only show the predicted coding potential. The “gene_biotype” in the result spreadsheet is from the database record. Therefore, if you find conflicts between “gene_biotype” and “codingPotential”, please trust the “gene_biotype”.

    • Notes on IDR and IDR_w_binding: As the prediction of Intrinsically Disordered Regions (IDR) and Intrinsically Disordered Binding Regions (IDBR) are done by two different tools we require two things to annotate the Intrinsically Disordered Binding Regions (IDBR). Firstly the IDBR (predicted by ANCHOR2) must be a region of at least 15 amino acids (after the smoothing). Secondly the fraction of the IDBR which overlaps the IDR predictions (done by IUPred3, again after smoothing) must be at least 80%. When that is the case the IDR type will be annotated as “IDR_w_binding_region” instead of just “IDR”. The current default parameters have not been rigorously tested and should be considered experimental.

    • For the function of any other domain, please Click HERE to search it through Pfam database.

Results

isoform_id gene_id condition_1 condition_2 gene_name gene_biotype iso_biotype gene_overall_mean gene_value_1 gene_value_2 gene_stderr_1 gene_stderr_2 gene_log2_fold_change iso_overall_mean iso_value_1 iso_value_2 iso_stderr_1 iso_stderr_2 iso_log2_fold_change IF_overall IF1 IF2 dIF isoform_switch_q_value gene_switch_q_value PTC codingPotential
ENST00000332345 ENSG00000169756 No_inf pgKDN_inf LIMS1 protein_coding protein_coding 156.1711 105.418 212.9379 1.224779 1.283447 1.014243 92.334055 47.939597 138.48421 7.2227537 7.933811 1.5302351 0.56972500 0.455050 0.650050 0.19500 0.10496919 0.03388354 FALSE TRUE
ENST00000393310 ENSG00000169756 No_inf pgKDN_inf LIMS1 protein_coding protein_coding 156.1711 105.418 212.9379 1.224779 1.283447 1.014243 13.580632 10.644570 17.01028 2.3560667 6.412434 0.6757827 0.08950000 0.101050 0.080200 -0.02085 0.84657453 0.03388354 FALSE TRUE
ENST00000544547 ENSG00000169756 No_inf pgKDN_inf LIMS1 protein_coding protein_coding 156.1711 105.418 212.9379 1.224779 1.283447 1.014243 23.388958 15.355664 29.18167 2.1057305 5.133465 0.9258467 0.15076667 0.145075 0.137425 -0.00765 0.95608030 0.03388354 FALSE TRUE
MSTRG.16813.25 ENSG00000169756 No_inf pgKDN_inf LIMS1 protein_coding   156.1711 105.418 212.9379 1.224779 1.283447 1.014243 7.272127 21.816382 0.00000 7.4542731 0.000000 -11.0918573 0.06901667 0.207050 0.000000 -0.20705 0.03388354 0.03388354 FALSE TRUE
MSTRG.16813.8 ENSG00000169756 No_inf pgKDN_inf LIMS1 protein_coding   156.1711 105.418 212.9379 1.224779 1.283447 1.014243 8.481960 3.638276 11.09866 0.9379974 3.691325 1.6063983 0.05274167 0.034725 0.052025 0.01730 0.83729822 0.03388354 FALSE TRUE
  • Note:
    • The comparisons made can be identified as “from ‘condition_1’ to ‘condition_2’”, meaning ‘condition_1’ is considered the ground state and ‘condition_2’ the changed state. This also means that a positive dIF value indicates that the isoform usage is increased in ‘condition_2’ compared to ‘condition_1’. Since the ‘isoformFeatures’ entry is the most relevant part of the switchAnalyzeRlist object, the most-used standard methods have also been implemented to work directly on isoformFeatures.

Help

Please Click HERE to learn more details about the results of IsoformSwitchAnalyzeR.

2 Differential Exon Usage

Counts

All exons whithin this gene region are shown and numbering below.

Expression

All exons whithin this gene region are shown and numbering below.

Splicing

All exons whithin this gene region are shown and numbering below.

Transcripts

All isoforms whithin this gene region are shown below.

Results

groupID featureID exonBaseMean dispersion pvalue padj seqnames start end width strand pgKDN.inf No.inf log2fold_No.inf_pgKDN.inf
ENSG00000169756 E001 0.3628435 0.0166686105 1.000000000   2 108533671 108533808 138 + 0.130 0.128 -0.036
ENSG00000169756 E002 0.9491777 0.0840030027 0.186607622 0.46459380 2 108534422 108534469 48 + 0.348 0.128 -1.842
ENSG00000169756 E003 10.1630739 0.0083648086 0.959183256 0.99036277 2 108534470 108534594 125 + 1.027 1.038 0.041
ENSG00000169756 E004 0.1176306 0.0117754219 1.000000000   2 108570704 108570800 97 + 0.070 0.000 -12.829
ENSG00000169756 E005 0.0000000       2 108580179 108580395 217 +      
ENSG00000169756 E006 1.2057433 0.0113096675 0.748081588 0.90061271 2 108588311 108588323 13 + 0.348 0.307 -0.258
ENSG00000169756 E007 1.4498186 0.0124457142 0.914018540 0.97292808 2 108588324 108588327 4 + 0.381 0.374 -0.036
ENSG00000169756 E008 2.6750113 0.0139911522 0.566674171 0.80470574 2 108588328 108588341 14 + 0.516 0.610 0.434
ENSG00000169756 E009 33.8082180 0.0005171354 0.147694456 0.40910856 2 108588342 108588425 84 + 1.544 1.483 -0.210
ENSG00000169756 E010 3.2580244 0.0047756067 0.570450994 0.80698725 2 108588426 108588465 40 + 0.636 0.572 -0.284
ENSG00000169756 E011 3.3802230 0.0160685167 0.777379213 0.91456820 2 108588466 108588496 31 + 0.636 0.610 -0.114
ENSG00000169756 E012 14.2369813 0.0073606891 0.365361113 0.65391487 2 108588497 108588628 132 + 1.187 1.124 -0.224
ENSG00000169756 E013 0.8256295 0.0381613389 0.038173850 0.18862305 2 108593888 108593936 49 + 0.348 0.000 -15.242
ENSG00000169756 E014 0.6015365 0.0482209831 0.496680789 0.75766660 2 108594471 108594622 152 + 0.231 0.128 -1.036
ENSG00000169756 E015 0.0000000       2 108607161 108607255 95 +      
ENSG00000169756 E016 0.1265070 0.0122971626 0.275834949   2 108621251 108621265 15 + 0.000 0.128 13.347
ENSG00000169756 E017 0.1265070 0.0122971626 0.275834949   2 108621266 108621272 7 + 0.000 0.128 13.347
ENSG00000169756 E018 0.9641590 0.0179050454 0.555036186 0.79775251 2 108621273 108621461 189 + 0.312 0.226 -0.621
ENSG00000169756 E019 0.0000000       2 108654812 108654918 107 +      
ENSG00000169756 E020 0.1268540 0.0123584784 0.275776763   2 108654919 108655011 93 + 0.000 0.128 13.345
ENSG00000169756 E021 0.1268540 0.0123584784 0.275776763   2 108655012 108655015 4 + 0.000 0.128 13.345
ENSG00000169756 E022 0.2541163 0.0160523269 0.091630687   2 108655016 108655036 21 + 0.000 0.226 14.271
ENSG00000169756 E023 0.2541163 0.0160523269 0.091630687   2 108655037 108655052 16 + 0.000 0.226 14.271
ENSG00000169756 E024 0.1272623 0.0123600330 0.275793142   2 108655053 108655256 204 + 0.000 0.128 13.345
ENSG00000169756 E025 0.0000000       2 108657894 108657940 47 +      
ENSG00000169756 E026 68.4637376 0.0008953565 0.035846390 0.18161947 2 108659605 108659694 90 + 1.845 1.779 -0.224
ENSG00000169756 E027 23.1421264 0.0066794565 0.938638331 0.98227560 2 108659695 108659764 70 + 1.360 1.372 0.042
ENSG00000169756 E028 0.0000000       2 108659765 108659945 181 +      
ENSG00000169756 E029 0.2448930 0.0163568920 0.625790698   2 108660153 108660313 161 + 0.070 0.128 0.964
ENSG00000169756 E030 0.0000000       2 108660616 108660701 86 +      
ENSG00000169756 E031 0.2444846 0.0163778006 0.625744862   2 108661729 108661785 57 + 0.070 0.128 0.964
ENSG00000169756 E032 1.0996024 0.0234941688 0.562547037 0.80237719 2 108662229 108662800 572 + 0.273 0.374 0.642
ENSG00000169756 E033 0.1272623 0.0123600330 0.275793142   2 108670759 108670780 22 + 0.000 0.128 13.345
ENSG00000169756 E034 0.1268540 0.0123584784 0.275776763   2 108670781 108670847 67 + 0.000 0.128 13.345
ENSG00000169756 E035 0.3646036 0.0166458991 1.000000000   2 108670848 108671005 158 + 0.131 0.128 -0.036
ENSG00000169756 E036 0.4896948 0.0158768064 0.536105344   2 108672325 108672445 121 + 0.130 0.226 0.964
ENSG00000169756 E037 0.0000000       2 108672880 108672927 48 +      
ENSG00000169756 E038 48.5922893 0.0012945035 0.666050289 0.86112658 2 108672928 108673029 102 + 1.663 1.701 0.128
ENSG00000169756 E039 1.7402597 0.0077230186 0.005921370 0.05597952 2 108673030 108673953 924 + 0.231 0.645 2.286
ENSG00000169756 E040 129.9696415 0.0008126985 0.503866659 0.76333655 2 108675878 108676028 151 + 2.099 2.097 -0.006
ENSG00000169756 E041 59.3244099 0.0032877771 0.011083387 0.08596168 2 108676606 108676698 93 + 1.796 1.692 -0.352
ENSG00000169756 E042 17.1826209 0.0009050331 0.666646739 0.86134299 2 108677979 108678027 49 + 1.247 1.232 -0.051
ENSG00000169756 E043 4.8246389 0.0275527688 0.001027338 0.01530197 2 108678715 108679429 715 + 0.538 0.980 1.800
ENSG00000169756 E044 68.5706508 0.0003270571 0.455561110 0.72805004 2 108680695 108680770 76 + 1.828 1.817 -0.036
ENSG00000169756 E045 0.7429595 0.3785450923 0.234234404 0.52322213 2 108680969 108681104 136 + 0.130 0.374 1.965
ENSG00000169756 E046 0.6158232 0.6895363799 0.545056144 0.79113633 2 108681105 108681112 8 + 0.130 0.306 1.550
ENSG00000169756 E047 1.1062733 0.4105602673 0.439832791 0.71565879 2 108681113 108681160 48 + 0.231 0.433 1.286
ENSG00000169756 E048 2467.2921602 0.0031072620 0.186825924 0.46486099 2 108683885 108687305 3421 + 3.365 3.389 0.081

Help

Please Click HERE to learn more details about the results from DEXseq.