ENSG00000169981

1 Isoform Switch

Summary Plot

Only the isoforms with fraction > 5% are shown below.

  • Note:

    • About the Coding Potential: Please check the spreadsheet in the “Results” tag to confirm the coding potential. The above figure only show the predicted coding potential. The “gene_biotype” in the result spreadsheet is from the database record. Therefore, if you find conflicts between “gene_biotype” and “codingPotential”, please trust the “gene_biotype”.

    • Notes on IDR and IDR_w_binding: As the prediction of Intrinsically Disordered Regions (IDR) and Intrinsically Disordered Binding Regions (IDBR) are done by two different tools we require two things to annotate the Intrinsically Disordered Binding Regions (IDBR). Firstly the IDBR (predicted by ANCHOR2) must be a region of at least 15 amino acids (after the smoothing). Secondly the fraction of the IDBR which overlaps the IDR predictions (done by IUPred3, again after smoothing) must be at least 80%. When that is the case the IDR type will be annotated as “IDR_w_binding_region” instead of just “IDR”. The current default parameters have not been rigorously tested and should be considered experimental.

    • For the function of any other domain, please Click HERE to search it through Pfam database.

Results

isoform_id gene_id condition_1 condition_2 gene_name gene_biotype iso_biotype gene_overall_mean gene_value_1 gene_value_2 gene_stderr_1 gene_stderr_2 gene_log2_fold_change iso_overall_mean iso_value_1 iso_value_2 iso_stderr_1 iso_stderr_2 iso_log2_fold_change IF_overall IF1 IF2 dIF isoform_switch_q_value gene_switch_q_value PTC codingPotential
ENST00000296092 ENSG00000169981 No_inf pgKDN_inf ZNF35 protein_coding protein_coding 5.888312 5.015729 6.793836 0.4570315 0.485126 0.4370154 1.4521679 0.0000000 3.260727 0.0000000 1.9083381 8.3534674 0.21710000 0.000000 0.44905 0.449050 6.063340e-01 3.844963e-05 FALSE TRUE
ENST00000396056 ENSG00000169981 No_inf pgKDN_inf ZNF35 protein_coding protein_coding 5.888312 5.015729 6.793836 0.4570315 0.485126 0.4370154 1.6596039 0.0000000 1.971233 0.0000000 0.9784258 7.6302545 0.29335000 0.000000 0.31060 0.310600 1.616064e-01 3.844963e-05 FALSE TRUE
ENST00000399560 ENSG00000169981 No_inf pgKDN_inf ZNF35 protein_coding protein_coding 5.888312 5.015729 6.793836 0.4570315 0.485126 0.4370154 1.0921187 1.7144790 1.561877 0.1532742 0.6790305 -0.1336723 0.19642500 0.348925 0.24035 -0.108575 8.129711e-01 3.844963e-05 FALSE TRUE
ENST00000415571 ENSG00000169981 No_inf pgKDN_inf ZNF35 protein_coding protein_coding 5.888312 5.015729 6.793836 0.4570315 0.485126 0.4370154 0.3460743 1.0382228 0.000000 0.5654734 0.0000000 -6.7118016 0.07133333 0.214000 0.00000 -0.214000 1.080971e-01 3.844963e-05 FALSE TRUE
ENST00000453164 ENSG00000169981 No_inf pgKDN_inf ZNF35 protein_coding protein_coding 5.888312 5.015729 6.793836 0.4570315 0.485126 0.4370154 0.9748616 1.7144790 0.000000 0.1532742 0.0000000 -7.4300168 0.16887500 0.348925 0.00000 -0.348925 3.844963e-05 3.844963e-05 FALSE TRUE
MSTRG.20023.1 ENSG00000169981 No_inf pgKDN_inf ZNF35 protein_coding   5.888312 5.015729 6.793836 0.4570315 0.485126 0.4370154 0.3634859 0.5485486 0.000000 0.5485486 0.0000000 -5.8036109 0.05291667 0.088125 0.00000 -0.088125 8.297023e-01 3.844963e-05 FALSE FALSE
  • Note:
    • The comparisons made can be identified as “from ‘condition_1’ to ‘condition_2’”, meaning ‘condition_1’ is considered the ground state and ‘condition_2’ the changed state. This also means that a positive dIF value indicates that the isoform usage is increased in ‘condition_2’ compared to ‘condition_1’. Since the ‘isoformFeatures’ entry is the most relevant part of the switchAnalyzeRlist object, the most-used standard methods have also been implemented to work directly on isoformFeatures.

Help

Please Click HERE to learn more details about the results of IsoformSwitchAnalyzeR.

2 Differential Exon Usage

Counts

All exons whithin this gene region are shown and numbering below.

Expression

All exons whithin this gene region are shown and numbering below.

Splicing

All exons whithin this gene region are shown and numbering below.

Transcripts

All isoforms whithin this gene region are shown below.

Results

groupID featureID exonBaseMean dispersion pvalue padj seqnames start end width strand pgKDN.inf No.inf log2fold_No.inf_pgKDN.inf
ENSG00000169981 E001 0.1271363 0.0125024491 0.375688883   3 44648663 44648731 69 + 0.000 0.109 10.221
ENSG00000169981 E002 0.1271363 0.0125024491 0.375688883   3 44648732 44648740 9 + 0.000 0.109 11.728
ENSG00000169981 E003 0.1271363 0.0125024491 0.375688883   3 44648741 44648741 1 + 0.000 0.109 11.728
ENSG00000169981 E004 0.1271363 0.0125024491 0.375688883   3 44648742 44648744 3 + 0.000 0.109 11.728
ENSG00000169981 E005 1.6620130 0.0096563903 0.003994188 0.04238099 3 44648745 44648811 67 + 0.571 0.109 -3.248
ENSG00000169981 E006 1.1799048 0.0120868501 0.002612901 0.03110223 3 44648812 44648834 23 + 0.490 0.000 -14.811
ENSG00000169981 E007 0.8248678 0.0143364711 0.015132527 0.10574731 3 44650941 44650943 3 + 0.392 0.000 -14.438
ENSG00000169981 E008 6.2887000 0.0038802816 0.193757398 0.47362619 3 44650944 44651259 316 + 0.920 0.768 -0.590
ENSG00000169981 E009 1.5911861 0.0100195242 0.729661183 0.89226950 3 44652557 44652701 145 + 0.392 0.434 0.230
ENSG00000169981 E010 62.1739140 0.0004704282 0.002722919 0.03205104 3 44658701 44660828 2128 + 1.784 1.814 0.100

Help

Please Click HERE to learn more details about the results from DEXseq.