ENSG00000170265

1 Isoform Switch

Summary Plot

Only the isoforms with fraction > 5% are shown below.

  • Note:

    • About the Coding Potential: Please check the spreadsheet in the “Results” tag to confirm the coding potential. The above figure only show the predicted coding potential. The “gene_biotype” in the result spreadsheet is from the database record. Therefore, if you find conflicts between “gene_biotype” and “codingPotential”, please trust the “gene_biotype”.

    • Notes on IDR and IDR_w_binding: As the prediction of Intrinsically Disordered Regions (IDR) and Intrinsically Disordered Binding Regions (IDBR) are done by two different tools we require two things to annotate the Intrinsically Disordered Binding Regions (IDBR). Firstly the IDBR (predicted by ANCHOR2) must be a region of at least 15 amino acids (after the smoothing). Secondly the fraction of the IDBR which overlaps the IDR predictions (done by IUPred3, again after smoothing) must be at least 80%. When that is the case the IDR type will be annotated as “IDR_w_binding_region” instead of just “IDR”. The current default parameters have not been rigorously tested and should be considered experimental.

    • For the function of any other domain, please Click HERE to search it through Pfam database.

Results

isoform_id gene_id condition_1 condition_2 gene_name gene_biotype iso_biotype gene_overall_mean gene_value_1 gene_value_2 gene_stderr_1 gene_stderr_2 gene_log2_fold_change iso_overall_mean iso_value_1 iso_value_2 iso_stderr_1 iso_stderr_2 iso_log2_fold_change IF_overall IF1 IF2 dIF isoform_switch_q_value gene_switch_q_value PTC codingPotential
ENST00000462740 ENSG00000170265 No_inf pgKDN_inf ZNF282 protein_coding retained_intron 11.99588 15.31062 10.2637 2.321911 0.5245673 -0.5765187 1.231775 3.695326 0.0000000 2.5003153 0.0000000 -8.533456 0.0624750 0.187425 0.000000 -0.187425 0.517135932 0.002234627   FALSE
ENST00000470381 ENSG00000170265 No_inf pgKDN_inf ZNF282 protein_coding retained_intron 11.99588 15.31062 10.2637 2.321911 0.5245673 -0.5765187 1.598140 4.144877 0.2108632 0.5418754 0.2108632 -4.233581 0.1110833 0.275275 0.019050 -0.256225 0.002234627 0.002234627 FALSE TRUE
ENST00000479907 ENSG00000170265 No_inf pgKDN_inf ZNF282 protein_coding protein_coding 11.99588 15.31062 10.2637 2.321911 0.5245673 -0.5765187 7.174660 7.470422 5.4643691 0.6158794 1.8934790 -0.450427 0.6225167 0.537325 0.506100 -0.031225 1.000000000 0.002234627 FALSE TRUE
ENST00000610704 ENSG00000170265 No_inf pgKDN_inf ZNF282 protein_coding protein_coding 11.99588 15.31062 10.2637 2.321911 0.5245673 -0.5765187 1.991307 0.000000 4.5884720 0.0000000 1.4971943 8.845011 0.2039417 0.000000 0.474875 0.474875 0.003276451 0.002234627 FALSE TRUE
  • Note:
    • The comparisons made can be identified as “from ‘condition_1’ to ‘condition_2’”, meaning ‘condition_1’ is considered the ground state and ‘condition_2’ the changed state. This also means that a positive dIF value indicates that the isoform usage is increased in ‘condition_2’ compared to ‘condition_1’. Since the ‘isoformFeatures’ entry is the most relevant part of the switchAnalyzeRlist object, the most-used standard methods have also been implemented to work directly on isoformFeatures.

Help

Please Click HERE to learn more details about the results of IsoformSwitchAnalyzeR.

2 Differential Exon Usage

Counts

All exons whithin this gene region are shown and numbering below.

Expression

All exons whithin this gene region are shown and numbering below.

Splicing

All exons whithin this gene region are shown and numbering below.

Transcripts

All isoforms whithin this gene region are shown below.

Results

groupID featureID exonBaseMean dispersion pvalue padj seqnames start end width strand pgKDN.inf No.inf log2fold_No.inf_pgKDN.inf
ENSG00000170265 E001 0.5879724 0.0158626080 1.559586e-02 0.1079362263 7 149195546 149195549 4 + 0.359 0.000 -11.668
ENSG00000170265 E002 6.1902142 0.0026258563 3.095647e-02 0.1657177282 7 149195550 149195754 205 + 0.965 0.735 -0.890
ENSG00000170265 E003 19.5251570 0.0008133358 3.754538e-02 0.1867883350 7 149198333 149198752 420 + 1.378 1.245 -0.464
ENSG00000170265 E004 0.3807797 0.0348889693 1.247664e-01   7 149206636 149206695 60 + 0.000 0.230 11.669
ENSG00000170265 E005 11.3633372 0.0015412251 2.354993e-01 0.5248304470 7 149206696 149206822 127 + 1.141 1.043 -0.356
ENSG00000170265 E006 11.4173186 0.0012196653 5.648497e-03 0.0540823747 7 149207351 149207470 120 + 1.201 0.973 -0.826
ENSG00000170265 E007 11.2345408 0.0014663992 1.958386e-01 0.4762853287 7 149210585 149210704 120 + 1.141 1.033 -0.390
ENSG00000170265 E008 0.7439024 0.0141223469 4.796590e-01 0.7453235454 7 149212308 149212357 50 + 0.180 0.286 0.862
ENSG00000170265 E009 10.9316724 0.0013366139 7.568995e-01 0.9042999870 7 149212358 149212471 114 + 1.062 1.086 0.089
ENSG00000170265 E010 7.3680205 0.0024061539 8.738796e-01 0.9569172168 7 149213701 149213814 114 + 0.913 0.928 0.055
ENSG00000170265 E011 5.0168459 0.0034589834 6.518424e-01 0.8533537670 7 149223812 149223990 179 + 0.806 0.753 -0.208
ENSG00000170265 E012 6.3655024 0.0278683558 7.583226e-01 0.9051436528 7 149223991 149224247 257 + 0.885 0.849 -0.138
ENSG00000170265 E013 120.6351083 0.0001757961 8.051089e-06 0.0002834383 7 149224248 149226238 1991 + 2.038 2.119 0.271

Help

Please Click HERE to learn more details about the results from DEXseq.