ENSG00000170412

1 Isoform Switch

Summary Plot

Only the isoforms with fraction > 5% are shown below.

  • Note:

    • About the Coding Potential: Please check the spreadsheet in the “Results” tag to confirm the coding potential. The above figure only show the predicted coding potential. The “gene_biotype” in the result spreadsheet is from the database record. Therefore, if you find conflicts between “gene_biotype” and “codingPotential”, please trust the “gene_biotype”.

    • Notes on IDR and IDR_w_binding: As the prediction of Intrinsically Disordered Regions (IDR) and Intrinsically Disordered Binding Regions (IDBR) are done by two different tools we require two things to annotate the Intrinsically Disordered Binding Regions (IDBR). Firstly the IDBR (predicted by ANCHOR2) must be a region of at least 15 amino acids (after the smoothing). Secondly the fraction of the IDBR which overlaps the IDR predictions (done by IUPred3, again after smoothing) must be at least 80%. When that is the case the IDR type will be annotated as “IDR_w_binding_region” instead of just “IDR”. The current default parameters have not been rigorously tested and should be considered experimental.

    • For the function of any other domain, please Click HERE to search it through Pfam database.

Results

isoform_id gene_id condition_1 condition_2 gene_name gene_biotype iso_biotype gene_overall_mean gene_value_1 gene_value_2 gene_stderr_1 gene_stderr_2 gene_log2_fold_change iso_overall_mean iso_value_1 iso_value_2 iso_stderr_1 iso_stderr_2 iso_log2_fold_change IF_overall IF1 IF2 dIF isoform_switch_q_value gene_switch_q_value PTC codingPotential
ENST00000342648 ENSG00000170412 No_inf pgKDN_inf GPRC5C protein_coding protein_coding 8.27769 3.782242 8.726482 0.657702 0.7587092 1.204001 0.4721089 0.0000000 0.84791941 0.00000000 0.59175941 6.422770 0.04772500 0.000000 0.086350 0.086350 0.706199177 0.006242462 FALSE FALSE
ENST00000392627 ENSG00000170412 No_inf pgKDN_inf GPRC5C protein_coding protein_coding 8.27769 3.782242 8.726482 0.657702 0.7587092 1.204001 2.5196833 0.6806154 4.91933338 0.23261604 0.73625639 2.835438 0.31045833 0.159425 0.576825 0.417400 0.087096205 0.006242462 FALSE TRUE
ENST00000481232 ENSG00000170412 No_inf pgKDN_inf GPRC5C protein_coding protein_coding 8.27769 3.782242 8.726482 0.657702 0.7587092 1.204001 0.6273919 0.0000000 1.05356205 0.00000000 0.66021352 6.732760 0.06645833 0.000000 0.117525 0.117525 0.677370367 0.006242462 FALSE FALSE
ENST00000577663 ENSG00000170412 No_inf pgKDN_inf GPRC5C protein_coding retained_intron 8.27769 3.782242 8.726482 0.657702 0.7587092 1.204001 0.1250984 0.2606914 0.05909391 0.07072749 0.03413209 -1.970019 0.02580000 0.065275 0.007375 -0.057900 0.373266625 0.006242462 FALSE FALSE
ENST00000582873 ENSG00000170412 No_inf pgKDN_inf GPRC5C protein_coding protein_coding_CDS_not_defined 8.27769 3.782242 8.726482 0.657702 0.7587092 1.204001 2.3854016 2.2896109 0.56160387 0.32154333 0.56160387 -2.008302 0.33036667 0.619775 0.057475 -0.562300 0.006242462 0.006242462 FALSE FALSE
ENST00000652232 ENSG00000170412 No_inf pgKDN_inf GPRC5C protein_coding protein_coding 8.27769 3.782242 8.726482 0.657702 0.7587092 1.204001 0.5934842 0.2595043 0.61828871 0.15360622 0.35763129 1.221119 0.07357500 0.078200 0.077375 -0.000825 0.987181331 0.006242462 FALSE TRUE
  • Note:
    • The comparisons made can be identified as “from ‘condition_1’ to ‘condition_2’”, meaning ‘condition_1’ is considered the ground state and ‘condition_2’ the changed state. This also means that a positive dIF value indicates that the isoform usage is increased in ‘condition_2’ compared to ‘condition_1’. Since the ‘isoformFeatures’ entry is the most relevant part of the switchAnalyzeRlist object, the most-used standard methods have also been implemented to work directly on isoformFeatures.

Help

Please Click HERE to learn more details about the results of IsoformSwitchAnalyzeR.

2 Differential Exon Usage

Counts

All exons whithin this gene region are shown and numbering below.

Expression

All exons whithin this gene region are shown and numbering below.

Splicing

All exons whithin this gene region are shown and numbering below.

Transcripts

All isoforms whithin this gene region are shown below.

Results

groupID featureID exonBaseMean dispersion pvalue padj seqnames start end width strand pgKDN.inf No.inf log2fold_No.inf_pgKDN.inf
ENSG00000170412 E001 0.0000000       17 74424851 74424932 82 +      
ENSG00000170412 E002 0.4731135 0.267961577 0.5564213921   17 74431384 74431527 144 + 0.188 0.000 -10.506
ENSG00000170412 E003 1.7802805 0.076445708 0.1050244530 0.338906433 17 74431528 74431835 308 + 0.461 0.159 -2.094
ENSG00000170412 E004 1.3146913 0.010947707 0.6669357144 0.861475300 17 74431836 74432087 252 + 0.346 0.276 -0.457
ENSG00000170412 E005 1.3127738 0.010921897 0.6646789575 0.860591389 17 74432088 74432115 28 + 0.346 0.276 -0.457
ENSG00000170412 E006 1.0695800 0.011107615 0.3634059693 0.652335549 17 74432116 74432132 17 + 0.318 0.159 -1.287
ENSG00000170412 E007 1.0695800 0.011107615 0.3634059693 0.652335549 17 74432133 74432141 9 + 0.318 0.159 -1.287
ENSG00000170412 E008 0.2346346 0.016146480 1.0000000000   17 74432142 74432523 382 + 0.104 0.000 -11.472
ENSG00000170412 E009 0.0000000       17 74433697 74433757 61 +      
ENSG00000170412 E010 2.7217114 0.005327945 0.0103152368 0.081935491 17 74439745 74439895 151 + 0.599 0.159 -2.746
ENSG00000170412 E011 3.3480107 0.004810936 0.4446022713 0.719145240 17 74439896 74440046 151 + 0.614 0.507 -0.489
ENSG00000170412 E012 10.6628395 0.002763673 0.3989468911 0.682729364 17 74440047 74440682 636 + 1.025 0.953 -0.267
ENSG00000170412 E013 4.5357893 0.003554859 0.2185589363 0.505153532 17 74440683 74440827 145 + 0.726 0.563 -0.702
ENSG00000170412 E014 0.1272623 0.012498598 0.1297235611   17 74443077 74443084 8 + 0.000 0.159 12.795
ENSG00000170412 E015 0.1272623 0.012498598 0.1297235611   17 74443085 74443134 50 + 0.000 0.159 12.795
ENSG00000170412 E016 1.9591309 0.050571993 0.0297028686 0.162077763 17 74443135 74443817 683 + 0.318 0.658 1.713
ENSG00000170412 E017 6.0302089 0.002627826 0.2850697343 0.578783524 17 74443818 74443912 95 + 0.758 0.884 0.491
ENSG00000170412 E018 1.3794614 0.009791366 0.0000453168 0.001230054 17 74445204 74446848 1645 + 0.104 0.698 3.883
ENSG00000170412 E019 7.4325000 0.005945616 0.8632246022 0.952789576 17 74446849 74446998 150 + 0.874 0.858 -0.064
ENSG00000170412 E020 9.7558746 0.001520693 0.2828528578 0.576501626 17 74446999 74447429 431 + 0.946 1.049 0.379
ENSG00000170412 E021 0.0000000       17 74448823 74448915 93 +      
ENSG00000170412 E022 0.3645386 0.205418384 0.6718480165   17 74449335 74450580 1246 + 0.104 0.159 0.713
ENSG00000170412 E023 0.6086152 0.015729213 0.4108796962 0.692638174 17 74450887 74451653 767 + 0.148 0.276 1.128

Help

Please Click HERE to learn more details about the results from DEXseq.