ENSG00000170632

1 Isoform Switch

Summary Plot

Only the isoforms with fraction > 5% are shown below.

  • Note:

    • About the Coding Potential: Please check the spreadsheet in the “Results” tag to confirm the coding potential. The above figure only show the predicted coding potential. The “gene_biotype” in the result spreadsheet is from the database record. Therefore, if you find conflicts between “gene_biotype” and “codingPotential”, please trust the “gene_biotype”.

    • Notes on IDR and IDR_w_binding: As the prediction of Intrinsically Disordered Regions (IDR) and Intrinsically Disordered Binding Regions (IDBR) are done by two different tools we require two things to annotate the Intrinsically Disordered Binding Regions (IDBR). Firstly the IDBR (predicted by ANCHOR2) must be a region of at least 15 amino acids (after the smoothing). Secondly the fraction of the IDBR which overlaps the IDR predictions (done by IUPred3, again after smoothing) must be at least 80%. When that is the case the IDR type will be annotated as “IDR_w_binding_region” instead of just “IDR”. The current default parameters have not been rigorously tested and should be considered experimental.

    • For the function of any other domain, please Click HERE to search it through Pfam database.

Results

isoform_id gene_id condition_1 condition_2 gene_name gene_biotype iso_biotype gene_overall_mean gene_value_1 gene_value_2 gene_stderr_1 gene_stderr_2 gene_log2_fold_change iso_overall_mean iso_value_1 iso_value_2 iso_stderr_1 iso_stderr_2 iso_log2_fold_change IF_overall IF1 IF2 dIF isoform_switch_q_value gene_switch_q_value PTC codingPotential
ENST00000323716 ENSG00000170632 No_inf pgKDN_inf ARMC10 protein_coding protein_coding 15.98087 14.96221 18.0608 0.3812121 0.3162455 0.2713731 5.0680119 5.212601 5.123860 2.050327 2.484336 -0.02472447 0.31986667 0.354450 0.281000 -0.073450 0.92627330 0.04982884 FALSE TRUE
ENST00000431642 ENSG00000170632 No_inf pgKDN_inf ARMC10 protein_coding protein_coding 15.98087 14.96221 18.0608 0.3812121 0.3162455 0.2713731 0.6716004 2.014801 0.000000 0.885883 0.000000 -7.66163648 0.04403333 0.132100 0.000000 -0.132100 0.04982884 0.04982884 FALSE TRUE
ENST00000441711 ENSG00000170632 No_inf pgKDN_inf ARMC10 protein_coding protein_coding 15.98087 14.96221 18.0608 0.3812121 0.3162455 0.2713731 5.7211864 2.842679 7.723710 1.777552 2.929224 1.43884315 0.35310000 0.185975 0.429525 0.243550 0.68238032 0.04982884 FALSE TRUE
ENST00000454559 ENSG00000170632 No_inf pgKDN_inf ARMC10 protein_coding protein_coding 15.98087 14.96221 18.0608 0.3812121 0.3162455 0.2713731 3.3368844 4.144241 4.018188 1.006553 1.288590 -0.04445380 0.20833333 0.276450 0.223975 -0.052475 0.86490011 0.04982884 FALSE TRUE
  • Note:
    • The comparisons made can be identified as “from ‘condition_1’ to ‘condition_2’”, meaning ‘condition_1’ is considered the ground state and ‘condition_2’ the changed state. This also means that a positive dIF value indicates that the isoform usage is increased in ‘condition_2’ compared to ‘condition_1’. Since the ‘isoformFeatures’ entry is the most relevant part of the switchAnalyzeRlist object, the most-used standard methods have also been implemented to work directly on isoformFeatures.

Help

Please Click HERE to learn more details about the results of IsoformSwitchAnalyzeR.

2 Differential Exon Usage

Counts

All exons whithin this gene region are shown and numbering below.

Expression

All exons whithin this gene region are shown and numbering below.

Splicing

All exons whithin this gene region are shown and numbering below.

Transcripts

All isoforms whithin this gene region are shown below.

Results

groupID featureID exonBaseMean dispersion pvalue padj seqnames start end width strand pgKDN.inf No.inf log2fold_No.inf_pgKDN.inf
ENSG00000170632 E001 0.2452102 0.0162720791 0.888210873   7 103074881 103074925 45 + 0.088 0.103 0.257
ENSG00000170632 E002 0.8508364 0.0142851919 0.888601124 0.96276287 7 103074926 103074949 24 + 0.278 0.256 -0.158
ENSG00000170632 E003 2.7929600 0.0387153982 0.577580897 0.81126884 7 103074950 103075139 190 + 0.616 0.533 -0.380
ENSG00000170632 E004 2.0564254 0.0908688200 0.269741089 0.56334381 7 103075140 103075167 28 + 0.567 0.369 -1.007
ENSG00000170632 E005 10.1671703 0.0015342003 0.019916848 0.12668891 7 103075168 103075411 244 + 1.132 0.929 -0.743
ENSG00000170632 E006 2.5612521 0.0071884368 0.809463590 0.92970855 7 103075777 103075881 105 + 0.567 0.533 -0.158
ENSG00000170632 E007 0.1272623 0.0124883813 0.448354275   7 103081882 103081908 27 + 0.000 0.103 10.613
ENSG00000170632 E008 0.2441403 0.0162877518 0.889088352   7 103083066 103083132 67 + 0.088 0.103 0.257
ENSG00000170632 E009 8.2767005 0.0428713812 0.505311061 0.76413026 7 103083682 103083830 149 + 1.008 0.915 -0.347
ENSG00000170632 E010 0.1268540 0.0123255429 0.448655292   7 103083831 103084029 199 + 0.000 0.103 10.613
ENSG00000170632 E011 0.2444846 0.0162621385 0.888920840   7 103084030 103084062 33 + 0.088 0.103 0.257
ENSG00000170632 E012 2.0653577 0.0089145649 0.400875778 0.68411895 7 103086630 103086638 9 + 0.539 0.416 -0.617
ENSG00000170632 E013 15.4228149 0.0016230464 0.144736077 0.40494447 7 103086639 103086764 126 + 1.261 1.158 -0.366
ENSG00000170632 E014 0.4821733 0.0183252937 0.414094580   7 103086869 103086937 69 + 0.223 0.103 -1.328
ENSG00000170632 E015 11.9287616 0.0016984687 0.453229632 0.72601960 7 103092477 103092653 177 + 1.139 1.078 -0.218
ENSG00000170632 E016 3.2282552 0.0067658078 0.015623821 0.10810201 7 103095727 103097276 1550 + 0.446 0.765 1.427
ENSG00000170632 E017 17.5932952 0.0010750577 0.797335400 0.92348622 7 103097277 103097348 72 + 1.261 1.277 0.057
ENSG00000170632 E018 50.6275704 0.0003669322 0.002626487 0.03121572 7 103098299 103099759 1461 + 1.663 1.761 0.334

Help

Please Click HERE to learn more details about the results from DEXseq.