ENSG00000170638

1 Isoform Switch

Summary Plot

Only the isoforms with fraction > 5% are shown below.

  • Note:

    • About the Coding Potential: Please check the spreadsheet in the “Results” tag to confirm the coding potential. The above figure only show the predicted coding potential. The “gene_biotype” in the result spreadsheet is from the database record. Therefore, if you find conflicts between “gene_biotype” and “codingPotential”, please trust the “gene_biotype”.

    • Notes on IDR and IDR_w_binding: As the prediction of Intrinsically Disordered Regions (IDR) and Intrinsically Disordered Binding Regions (IDBR) are done by two different tools we require two things to annotate the Intrinsically Disordered Binding Regions (IDBR). Firstly the IDBR (predicted by ANCHOR2) must be a region of at least 15 amino acids (after the smoothing). Secondly the fraction of the IDBR which overlaps the IDR predictions (done by IUPred3, again after smoothing) must be at least 80%. When that is the case the IDR type will be annotated as “IDR_w_binding_region” instead of just “IDR”. The current default parameters have not been rigorously tested and should be considered experimental.

    • For the function of any other domain, please Click HERE to search it through Pfam database.

Results

isoform_id gene_id condition_1 condition_2 gene_name gene_biotype iso_biotype gene_overall_mean gene_value_1 gene_value_2 gene_stderr_1 gene_stderr_2 gene_log2_fold_change iso_overall_mean iso_value_1 iso_value_2 iso_stderr_1 iso_stderr_2 iso_log2_fold_change IF_overall IF1 IF2 dIF isoform_switch_q_value gene_switch_q_value PTC codingPotential
ENST00000303434 ENSG00000170638 No_inf pgKDN_inf TRABD protein_coding protein_coding 35.7002 36.07804 29.33007 0.2530163 1.235653 -0.2986488 6.984501 0.000000 7.293981 0.000000 3.4818240 9.51253927 0.19105000 0.000000 0.23855 0.238550 0.009188529 0.009188529 FALSE TRUE
ENST00000380909 ENSG00000170638 No_inf pgKDN_inf TRABD protein_coding protein_coding 35.7002 36.07804 29.33007 0.2530163 1.235653 -0.2986488 14.611998 14.656942 13.946605 1.060318 2.2361560 -0.07162004 0.41904167 0.406225 0.48720 0.080975 0.840746904 0.009188529 FALSE TRUE
ENST00000395827 ENSG00000170638 No_inf pgKDN_inf TRABD protein_coding protein_coding 35.7002 36.07804 29.33007 0.2530163 1.235653 -0.2986488 1.955271 2.674375 1.266622 1.128958 1.2666224 -1.07225428 0.05334167 0.073875 0.04125 -0.032625 0.517876656 0.009188529 FALSE TRUE
ENST00000395829 ENSG00000170638 No_inf pgKDN_inf TRABD protein_coding protein_coding 35.7002 36.07804 29.33007 0.2530163 1.235653 -0.2986488 2.136266 3.144666 0.000000 1.177429 0.0000000 -8.30134335 0.05477500 0.087625 0.00000 -0.087625 0.045679344 0.009188529 FALSE TRUE
ENST00000463233 ENSG00000170638 No_inf pgKDN_inf TRABD protein_coding retained_intron 35.7002 36.07804 29.33007 0.2530163 1.235653 -0.2986488 8.487349 13.169368 6.258636 0.268368 0.9175978 -1.07205786 0.24030000 0.365050 0.21385 -0.151200 0.213903301 0.009188529 TRUE TRUE
  • Note:
    • The comparisons made can be identified as “from ‘condition_1’ to ‘condition_2’”, meaning ‘condition_1’ is considered the ground state and ‘condition_2’ the changed state. This also means that a positive dIF value indicates that the isoform usage is increased in ‘condition_2’ compared to ‘condition_1’. Since the ‘isoformFeatures’ entry is the most relevant part of the switchAnalyzeRlist object, the most-used standard methods have also been implemented to work directly on isoformFeatures.

Help

Please Click HERE to learn more details about the results of IsoformSwitchAnalyzeR.

2 Differential Exon Usage

Counts

All exons whithin this gene region are shown and numbering below.

Expression

All exons whithin this gene region are shown and numbering below.

Splicing

All exons whithin this gene region are shown and numbering below.

Transcripts

All isoforms whithin this gene region are shown below.

Results

groupID featureID exonBaseMean dispersion pvalue padj seqnames start end width strand pgKDN.inf No.inf log2fold_No.inf_pgKDN.inf
ENSG00000170638 E001 0.1186381 0.0118242213 0.4009465589   22 50185913 50185916 4 + 0.108 0.000 -11.329
ENSG00000170638 E002 0.3542802 0.0243648475 0.0597099622   22 50185917 50185917 1 + 0.267 0.000 -12.914
ENSG00000170638 E003 8.3200095 0.0031626510 0.1622848064 0.430680772 22 50185918 50185976 59 + 1.037 0.903 -0.499
ENSG00000170638 E004 2.9190880 0.0056416963 0.1346980010 0.390164397 22 50185977 50186001 25 + 0.695 0.494 -0.899
ENSG00000170638 E005 1.8719234 0.2898191419 0.2870020809 0.580396334 22 50190598 50190648 51 + 0.329 0.523 1.044
ENSG00000170638 E006 0.2536433 0.0161183437 0.3583518259   22 50193014 50193026 13 + 0.000 0.154 11.396
ENSG00000170638 E007 16.2017975 0.0008901221 0.3416071549 0.633099834 22 50193027 50193093 67 + 1.268 1.200 -0.239
ENSG00000170638 E008 17.4978432 0.0008064385 0.0479072178 0.215377398 22 50193576 50193654 79 + 1.335 1.200 -0.474
ENSG00000170638 E009 34.0583775 0.0004145535 0.5982054601 0.823828953 22 50194340 50194506 167 + 1.553 1.527 -0.090
ENSG00000170638 E010 43.2138612 0.0003450765 0.1130015143 0.353701101 22 50194900 50195040 141 + 1.596 1.666 0.240
ENSG00000170638 E011 1.8784708 0.0081743624 0.0640628685 0.254924377 22 50196893 50197240 348 + 0.267 0.550 1.586
ENSG00000170638 E012 42.4007055 0.0004509395 0.5369275720 0.786126143 22 50197241 50197351 111 + 1.614 1.642 0.095
ENSG00000170638 E013 1.7478453 0.0579678572 0.1170107045 0.361053569 22 50197352 50197448 97 + 0.267 0.523 1.461
ENSG00000170638 E014 41.1274021 0.0004800287 0.0704740447 0.268770126 22 50197449 50197588 140 + 1.567 1.650 0.284
ENSG00000170638 E015 5.1341750 0.0234068867 0.0041736079 0.043761489 22 50197589 50197822 234 + 0.513 0.903 1.631
ENSG00000170638 E016 40.9536711 0.0061966132 0.1085678117 0.345701757 22 50197823 50197995 173 + 1.665 1.579 -0.293
ENSG00000170638 E017 8.4452493 0.0016721945 0.0428115166 0.201676683 22 50197996 50198074 79 + 0.841 1.040 0.748
ENSG00000170638 E018 32.7770336 0.0004417106 0.2291351567 0.517793266 22 50198075 50198186 112 + 1.557 1.496 -0.208
ENSG00000170638 E019 47.4273091 0.0030060839 0.0207073533 0.129616632 22 50198345 50198515 171 + 1.738 1.631 -0.362
ENSG00000170638 E020 76.1328627 0.0002954202 0.6221424526 0.837170506 22 50198516 50199115 600 + 1.890 1.874 -0.053
ENSG00000170638 E021 22.1465556 0.0115582605 0.0005534149 0.009454506 22 50199116 50199598 483 + 1.180 1.449 0.942

Help

Please Click HERE to learn more details about the results from DEXseq.