ENSG00000170776

1 Isoform Switch

Summary Plot

Only the isoforms with fraction > 5% are shown below.

  • Note:

    • About the Coding Potential: Please check the spreadsheet in the “Results” tag to confirm the coding potential. The above figure only show the predicted coding potential. The “gene_biotype” in the result spreadsheet is from the database record. Therefore, if you find conflicts between “gene_biotype” and “codingPotential”, please trust the “gene_biotype”.

    • Notes on IDR and IDR_w_binding: As the prediction of Intrinsically Disordered Regions (IDR) and Intrinsically Disordered Binding Regions (IDBR) are done by two different tools we require two things to annotate the Intrinsically Disordered Binding Regions (IDBR). Firstly the IDBR (predicted by ANCHOR2) must be a region of at least 15 amino acids (after the smoothing). Secondly the fraction of the IDBR which overlaps the IDR predictions (done by IUPred3, again after smoothing) must be at least 80%. When that is the case the IDR type will be annotated as “IDR_w_binding_region” instead of just “IDR”. The current default parameters have not been rigorously tested and should be considered experimental.

    • For the function of any other domain, please Click HERE to search it through Pfam database.

Results

isoform_id gene_id condition_1 condition_2 gene_name gene_biotype iso_biotype gene_overall_mean gene_value_1 gene_value_2 gene_stderr_1 gene_stderr_2 gene_log2_fold_change iso_overall_mean iso_value_1 iso_value_2 iso_stderr_1 iso_stderr_2 iso_log2_fold_change IF_overall IF1 IF2 dIF isoform_switch_q_value gene_switch_q_value PTC codingPotential
ENST00000557852 ENSG00000170776 No_inf pgKDN_inf AKAP13 protein_coding protein_coding 43.34772 34.72246 47.61898 1.404883 1.564338 0.4555551 0.6407892 1.92236750 0.000000 0.65295497 0.0000000 -7.5942257 0.01921667 0.057650 0.00000 -0.057650 3.207054e-02 2.149746e-05 FALSE FALSE
ENST00000560185 ENSG00000170776 No_inf pgKDN_inf AKAP13 protein_coding protein_coding_CDS_not_defined 43.34772 34.72246 47.61898 1.404883 1.564338 0.4555551 11.3659267 11.91661354 9.024875 1.44718630 1.5781070 -0.4006079 0.26757500 0.341625 0.18780 -0.153825 2.149032e-01 2.149746e-05   FALSE
MSTRG.10135.15 ENSG00000170776 No_inf pgKDN_inf AKAP13 protein_coding   43.34772 34.72246 47.61898 1.404883 1.564338 0.4555551 3.0238109 0.05651489 5.751433 0.05651489 1.4982024 6.4366067 0.06447500 0.001800 0.12420 0.122400 2.149746e-05 2.149746e-05 FALSE TRUE
MSTRG.10135.23 ENSG00000170776 No_inf pgKDN_inf AKAP13 protein_coding   43.34772 34.72246 47.61898 1.404883 1.564338 0.4555551 1.5684866 2.02917324 0.000000 0.74713574 0.0000000 -7.6718405 0.03874167 0.060150 0.00000 -0.060150 3.065377e-02 2.149746e-05 FALSE TRUE
MSTRG.10135.24 ENSG00000170776 No_inf pgKDN_inf AKAP13 protein_coding   43.34772 34.72246 47.61898 1.404883 1.564338 0.4555551 1.7515063 0.82639637 3.892082 0.82639637 2.6192425 2.2219853 0.04020000 0.021575 0.08725 0.065675 8.259075e-01 2.149746e-05 FALSE TRUE
MSTRG.10135.32 ENSG00000170776 No_inf pgKDN_inf AKAP13 protein_coding   43.34772 34.72246 47.61898 1.404883 1.564338 0.4555551 5.0020583 2.87141674 5.489567 1.03179355 1.9022077 0.9325398 0.11277500 0.085525 0.11155 0.026025 9.639608e-01 2.149746e-05 FALSE TRUE
MSTRG.10135.35 ENSG00000170776 No_inf pgKDN_inf AKAP13 protein_coding   43.34772 34.72246 47.61898 1.404883 1.564338 0.4555551 8.5044657 6.89987944 8.383152 0.79064181 0.9358231 0.2805521 0.19707500 0.199300 0.17640 -0.022900 8.955220e-01 2.149746e-05 FALSE TRUE
  • Note:
    • The comparisons made can be identified as “from ‘condition_1’ to ‘condition_2’”, meaning ‘condition_1’ is considered the ground state and ‘condition_2’ the changed state. This also means that a positive dIF value indicates that the isoform usage is increased in ‘condition_2’ compared to ‘condition_1’. Since the ‘isoformFeatures’ entry is the most relevant part of the switchAnalyzeRlist object, the most-used standard methods have also been implemented to work directly on isoformFeatures.

Help

Please Click HERE to learn more details about the results of IsoformSwitchAnalyzeR.

2 Differential Exon Usage

Counts

All exons whithin this gene region are shown and numbering below.

Expression

All exons whithin this gene region are shown and numbering below.

Splicing

All exons whithin this gene region are shown and numbering below.

Transcripts

All isoforms whithin this gene region are shown below.

Results

groupID featureID exonBaseMean dispersion pvalue padj seqnames start end width strand pgKDN.inf No.inf log2fold_No.inf_pgKDN.inf
ENSG00000170776 E001 0.0000000       15 85380571 85380586 16 +      
ENSG00000170776 E002 0.0000000       15 85380587 85380595 9 +      
ENSG00000170776 E003 0.0000000       15 85380596 85380602 7 +      
ENSG00000170776 E004 0.1265070 0.0122638350 0.2843704789   15 85380603 85380639 37 + 0.000 0.125 10.220
ENSG00000170776 E005 0.5077596 0.0150405437 0.0094546451 0.0775436171 15 85380640 85380728 89 + 0.000 0.368 14.441
ENSG00000170776 E006 0.4999558 0.0153596517 0.1118200997 0.3512262102 15 85380729 85380755 27 + 0.072 0.301 2.471
ENSG00000170776 E007 0.6185939 0.0143879954 0.2683009370 0.5618319124 15 85380756 85380798 43 + 0.134 0.301 1.471
ENSG00000170776 E008 0.4912665 0.1040673137 0.5637692209   15 85381687 85382170 484 + 0.134 0.222 0.886
ENSG00000170776 E009 0.1187032 0.0118382140 1.0000000000   15 85480873 85481026 154 + 0.072 0.000 -12.314
ENSG00000170776 E010 0.7373883 0.4367203370 0.7056067757 0.8804209563 15 85485710 85485753 44 + 0.188 0.301 0.885
ENSG00000170776 E011 0.8645856 0.5553508560 0.3836031907 0.6696851974 15 85521428 85521575 148 + 0.188 0.368 1.300
ENSG00000170776 E012 1.9286012 0.0094909468 0.7274817949 0.8912412122 15 85533584 85533880 297 + 0.474 0.426 -0.251
ENSG00000170776 E013 0.6079886 0.0143358839 0.8337574270 0.9401261574 15 85533881 85536997 3117 + 0.188 0.222 0.301
ENSG00000170776 E014 0.3533378 0.0157572541 0.2818914721   15 85543772 85543789 18 + 0.188 0.000 -13.803
ENSG00000170776 E015 2.2983009 0.0148568547 0.7300208494 0.8925474235 15 85543790 85543955 166 + 0.524 0.477 -0.229
ENSG00000170776 E016 0.0000000       15 85544040 85544143 104 +      
ENSG00000170776 E017 0.2340080 0.2556567414 0.5953154708   15 85555446 85555491 46 + 0.133 0.000 -12.633
ENSG00000170776 E018 5.4483625 0.0955332906 0.9687584650 0.9936412263 15 85575131 85575329 199 + 0.794 0.801 0.029
ENSG00000170776 E019 1.2330996 0.0427334086 0.1323933631 0.3861819170 15 85577763 85577871 109 + 0.236 0.477 1.471
ENSG00000170776 E020 3.2367874 0.0970225351 0.2807764135 0.5739317146 15 85578930 85579553 624 + 0.679 0.477 -0.921
ENSG00000170776 E021 21.0353174 0.0006676270 0.3674244947 0.6560101228 15 85579554 85580951 1398 + 1.347 1.293 -0.189
ENSG00000170776 E022 24.4420378 0.0032756578 0.5179158831 0.7732814720 15 85580952 85581858 907 + 1.403 1.367 -0.125
ENSG00000170776 E023 10.1184831 0.0102999880 0.1470180925 0.4081153842 15 85581859 85582107 249 + 1.079 0.937 -0.521
ENSG00000170776 E024 0.1176306 0.0118384009 1.0000000000   15 85582910 85583164 255 + 0.072 0.000 -12.314
ENSG00000170776 E025 8.7571181 0.0118055613 0.0202797517 0.1280459058 15 85585702 85585823 122 + 1.052 0.801 -0.947
ENSG00000170776 E026 0.0000000       15 85619696 85619949 254 +      
ENSG00000170776 E027 0.0000000       15 85619950 85620087 138 +      
ENSG00000170776 E028 0.0000000       15 85620088 85620172 85 +      
ENSG00000170776 E029 0.0000000       15 85635097 85635105 9 +      
ENSG00000170776 E030 5.4937189 0.0027031504 0.0023906932 0.0291389038 15 85639374 85639449 76 + 0.904 0.522 -1.592
ENSG00000170776 E031 7.5472437 0.0115439035 0.0075732339 0.0665777988 15 85645818 85645918 101 + 1.008 0.698 -1.201
ENSG00000170776 E032 4.4275377 0.0145916691 0.0361832682 0.1826570934 15 85645919 85645954 36 + 0.806 0.522 -1.213
ENSG00000170776 E033 8.0554559 0.1028830082 0.2054127377 0.4886661881 15 85655417 85655527 111 + 1.000 0.823 -0.668
ENSG00000170776 E034 18.3461805 0.0009856680 0.1811806475 0.4570381254 15 85655528 85655787 260 + 1.303 1.212 -0.318
ENSG00000170776 E035 7.6242340 0.0018381742 0.9319496110 0.9801636146 15 85658537 85658590 54 + 0.923 0.920 -0.012
ENSG00000170776 E036 1.3221883 0.0100722118 0.5682484188 0.8058029715 15 85662388 85662453 66 + 0.387 0.301 -0.529
ENSG00000170776 E037 13.4102975 0.0059811597 0.4126484309 0.6937803695 15 85664563 85664755 193 + 1.167 1.102 -0.232
ENSG00000170776 E038 9.0435575 0.0016241731 0.1745239093 0.4482913046 15 85669722 85669830 109 + 1.030 0.902 -0.476
ENSG00000170776 E039 0.0000000       15 85677037 85677098 62 +      
ENSG00000170776 E040 4.0558271 0.0033767977 0.0072270080 0.0644373370 15 85682158 85682167 10 + 0.794 0.426 -1.650
ENSG00000170776 E041 7.3331645 0.0018429280 0.0708040762 0.2694305767 15 85682168 85682212 45 + 0.968 0.778 -0.730
ENSG00000170776 E042 0.0000000       15 85683527 85683612 86 +      
ENSG00000170776 E043 0.2435110 0.0163392322 0.6405151987   15 85684422 85684740 319 + 0.072 0.125 0.886
ENSG00000170776 E044 13.6286227 0.0012662431 0.1645398682 0.4337980648 15 85684741 85684873 133 + 1.188 1.079 -0.391
ENSG00000170776 E045 0.0000000       15 85684874 85685446 573 +      
ENSG00000170776 E046 0.7612467 0.0137747110 0.0010271520 0.0153019720 15 85689869 85690104 236 + 0.000 0.477 14.988
ENSG00000170776 E047 0.0000000       15 85693099 85693276 178 +      
ENSG00000170776 E048 19.9196568 0.0017130489 0.2997589991 0.5926176407 15 85693277 85693451 175 + 1.329 1.263 -0.233
ENSG00000170776 E049 11.9337192 0.0056252655 0.1539845202 0.4190425737 15 85708019 85708086 68 + 1.139 1.014 -0.456
ENSG00000170776 E050 0.1170040 0.0117282637 1.0000000000   15 85710443 85710578 136 + 0.072 0.000 -12.315
ENSG00000170776 E051 6.7208381 0.0020911517 0.0238802730 0.1414561940 15 85710579 85710581 3 + 0.950 0.698 -0.988
ENSG00000170776 E052 12.9217560 0.0041941943 0.2485735385 0.5393908557 15 85710582 85710645 64 + 1.161 1.066 -0.343
ENSG00000170776 E053 16.4885877 0.0012997521 0.8858346787 0.9617450241 15 85715788 85715923 136 + 1.222 1.238 0.058
ENSG00000170776 E054 0.1186381 0.0118572942 1.0000000000   15 85717152 85717289 138 + 0.072 0.000 -12.314
ENSG00000170776 E055 12.7615454 0.0010876045 0.3357811946 0.6276651630 15 85717290 85717402 113 + 1.091 1.175 0.301
ENSG00000170776 E056 2.3039325 0.0059331420 0.8993854644 0.9671895128 15 85718007 85718009 3 + 0.500 0.522 0.109
ENSG00000170776 E057 2.4215631 0.0057291220 0.9678166604 0.9934949327 15 85718010 85718012 3 + 0.524 0.522 -0.007
ENSG00000170776 E058 15.1163478 0.0009303936 0.5377525379 0.7867393294 15 85718013 85718159 147 + 1.207 1.166 -0.148
ENSG00000170776 E059 0.1272623 0.0124605877 0.2841977088   15 85718801 85718875 75 + 0.000 0.125 12.544
ENSG00000170776 E060 16.4745057 0.0044902102 0.8344341339 0.9403559135 15 85719076 85719211 136 + 1.231 1.221 -0.035
ENSG00000170776 E061 17.9539206 0.0014577705 0.6685040421 0.8619435827 15 85719212 85719326 115 + 1.249 1.286 0.128
ENSG00000170776 E062 18.2095809 0.0007168923 0.5154699948 0.7714884754 15 85721991 85722116 126 + 1.249 1.300 0.180
ENSG00000170776 E063 0.0000000       15 85722117 85722229 113 +      
ENSG00000170776 E064 16.3245669 0.0008688044 0.6096936451 0.8301746289 15 85722230 85722347 118 + 1.236 1.203 -0.114
ENSG00000170776 E065 24.0619026 0.0019386188 0.0088402555 0.0740546784 15 85723072 85723320 249 + 1.439 1.270 -0.585
ENSG00000170776 E066 0.0000000       15 85726410 85726486 77 +      
ENSG00000170776 E067 1.4367006 0.0163876793 0.1567714339 0.4231481491 15 85727066 85727247 182 + 0.447 0.222 -1.436
ENSG00000170776 E068 2.1545133 0.0550549975 0.1090750751 0.3467029172 15 85727381 85727390 10 + 0.568 0.301 -1.436
ENSG00000170776 E069 10.9008079 0.0382854021 0.8946382894 0.9651828592 15 85727391 85727463 73 + 1.065 1.054 -0.042
ENSG00000170776 E070 25.6221483 0.0077050803 0.4510839146 0.7242254476 15 85730513 85730707 195 + 1.427 1.380 -0.165
ENSG00000170776 E071 22.3546317 0.0006404737 0.3910396087 0.6762972664 15 85734992 85735150 159 + 1.371 1.322 -0.173
ENSG00000170776 E072 13.1972972 0.0502267613 0.9701256884 0.9939545008 15 85735560 85735598 39 + 1.133 1.145 0.043
ENSG00000170776 E073 11.4811322 0.0145560754 0.6060727521 0.8284730393 15 85735599 85735630 32 + 1.098 1.054 -0.160
ENSG00000170776 E074 12.1918472 0.0011467049 0.3165368237 0.6094565560 15 85736090 85736134 45 + 1.134 1.054 -0.289
ENSG00000170776 E075 6.4885264 0.0021024365 0.0745058182 0.2782995091 15 85740222 85740224 3 + 0.923 0.726 -0.771
ENSG00000170776 E076 11.6670425 0.0027939827 0.0268333893 0.1520521138 15 85740225 85740272 48 + 1.151 0.954 -0.719
ENSG00000170776 E077 1.1063686 0.0109412130 0.2246239340 0.5121266171 15 85740273 85740562 290 + 0.236 0.426 1.208
ENSG00000170776 E078 39.0647563 0.0004614731 0.2680312823 0.5614852473 15 85741046 85741495 450 + 1.605 1.556 -0.168
ENSG00000170776 E079 26.2931087 0.0005251595 0.8761750015 0.9579748796 15 85743492 85743825 334 + 1.415 1.431 0.053
ENSG00000170776 E080 373.6729168 0.0000851555 0.2723127855 0.5660679019 15 85744628 85747603 2976 + 2.550 2.571 0.071
ENSG00000170776 E081 50.1194083 0.0003001816 0.0182311541 0.1192576183 15 85747604 85747809 206 + 1.651 1.758 0.362
ENSG00000170776 E082 175.6045963 0.0022465002 0.0000236444 0.0007108344 15 85747810 85748751 942 + 2.182 2.305 0.412
ENSG00000170776 E083 56.4546089 0.0066146305 0.0033249045 0.0373283514 15 85748752 85749369 618 + 1.680 1.836 0.529

Help

Please Click HERE to learn more details about the results from DEXseq.