ENSG00000170899

1 Isoform Switch

Summary Plot

Only the isoforms with fraction > 5% are shown below.

  • Note:

    • About the Coding Potential: Please check the spreadsheet in the “Results” tag to confirm the coding potential. The above figure only show the predicted coding potential. The “gene_biotype” in the result spreadsheet is from the database record. Therefore, if you find conflicts between “gene_biotype” and “codingPotential”, please trust the “gene_biotype”.

    • Notes on IDR and IDR_w_binding: As the prediction of Intrinsically Disordered Regions (IDR) and Intrinsically Disordered Binding Regions (IDBR) are done by two different tools we require two things to annotate the Intrinsically Disordered Binding Regions (IDBR). Firstly the IDBR (predicted by ANCHOR2) must be a region of at least 15 amino acids (after the smoothing). Secondly the fraction of the IDBR which overlaps the IDR predictions (done by IUPred3, again after smoothing) must be at least 80%. When that is the case the IDR type will be annotated as “IDR_w_binding_region” instead of just “IDR”. The current default parameters have not been rigorously tested and should be considered experimental.

    • For the function of any other domain, please Click HERE to search it through Pfam database.

Results

isoform_id gene_id condition_1 condition_2 gene_name gene_biotype iso_biotype gene_overall_mean gene_value_1 gene_value_2 gene_stderr_1 gene_stderr_2 gene_log2_fold_change iso_overall_mean iso_value_1 iso_value_2 iso_stderr_1 iso_stderr_2 iso_log2_fold_change IF_overall IF1 IF2 dIF isoform_switch_q_value gene_switch_q_value PTC codingPotential
ENST00000370963 ENSG00000170899 No_inf pgKDN_inf GSTA4 protein_coding protein_coding 6.311123 2.875903 3.26431 0.2244719 0.1931322 0.1821684 2.0389009 1.6943525 1.769190 0.6749837 0.7158542 0.06199683 0.54590833 0.553800 0.582825 0.029025 0.93575043 0.03411504 FALSE TRUE
ENST00000477599 ENSG00000170899 No_inf pgKDN_inf GSTA4 protein_coding protein_coding_CDS_not_defined 6.311123 2.875903 3.26431 0.2244719 0.1931322 0.1821684 0.7421584 0.3924516 1.373422 0.3924516 0.8024559 1.78135436 0.26237500 0.154375 0.382750 0.228375 0.80974221 0.03411504 FALSE TRUE
ENST00000486559 ENSG00000170899 No_inf pgKDN_inf GSTA4 protein_coding protein_coding_CDS_not_defined 6.311123 2.875903 3.26431 0.2244719 0.1931322 0.1821684 0.2409997 0.6583667 0.000000 0.1685290 0.0000000 -6.06256793 0.08916667 0.243675 0.000000 -0.243675 0.03411504 0.03411504 FALSE TRUE
MSTRG.24782.7 ENSG00000170899 No_inf pgKDN_inf GSTA4 protein_coding   6.311123 2.875903 3.26431 0.2244719 0.1931322 0.1821684 3.2049205 0.0000000 0.000000 0.0000000 0.0000000 0.00000000 0.07502500 0.000000 0.000000 0.000000   0.03411504   FALSE
  • Note:
    • The comparisons made can be identified as “from ‘condition_1’ to ‘condition_2’”, meaning ‘condition_1’ is considered the ground state and ‘condition_2’ the changed state. This also means that a positive dIF value indicates that the isoform usage is increased in ‘condition_2’ compared to ‘condition_1’. Since the ‘isoformFeatures’ entry is the most relevant part of the switchAnalyzeRlist object, the most-used standard methods have also been implemented to work directly on isoformFeatures.

Help

Please Click HERE to learn more details about the results of IsoformSwitchAnalyzeR.

2 Differential Exon Usage

Counts

All exons whithin this gene region are shown and numbering below.

Expression

All exons whithin this gene region are shown and numbering below.

Splicing

All exons whithin this gene region are shown and numbering below.

Transcripts

All isoforms whithin this gene region are shown below.

Results

groupID featureID exonBaseMean dispersion pvalue padj seqnames start end width strand pgKDN.inf No.inf log2fold_No.inf_pgKDN.inf
ENSG00000170899 E001 0.0000000       6 52977948 52977952 5 -      
ENSG00000170899 E002 4.6552291 0.003314004 0.816952817 0.93336864 6 52977953 52978254 302 - 0.753 0.751 -0.005
ENSG00000170899 E003 3.1686076 0.006206818 0.312681684 0.60610171 6 52978255 52978463 209 - 0.670 0.567 -0.452
ENSG00000170899 E004 3.2049624 0.005746336 0.518696843 0.77360231 6 52978464 52978592 129 - 0.568 0.669 0.442
ENSG00000170899 E005 1.9619830 0.065376094 0.927641163 0.97853270 6 52982574 52982622 49 - 0.472 0.471 -0.005
ENSG00000170899 E006 2.5415859 0.008921661 0.078552649 0.28719215 6 52982623 52982705 83 - 0.647 0.433 -1.005
ENSG00000170899 E007 0.1271363 0.012920188 0.574709847   6 52983627 52983681 55 - 0.000 0.095 11.380
ENSG00000170899 E008 3.1826931 0.031304198 0.837458618 0.94177129 6 52984464 52984605 142 - 0.622 0.621 -0.005
ENSG00000170899 E009 2.2230367 0.149180212 0.521934008 0.77563135 6 52985451 52985583 133 - 0.434 0.567 0.646
ENSG00000170899 E010 1.3625310 0.012025954 0.420780690 0.69995320 6 52987357 52987408 52 - 0.297 0.433 0.802
ENSG00000170899 E011 1.0153933 0.012860716 0.002426188 0.02943726 6 52987409 52988002 594 - 0.000 0.471 14.380
ENSG00000170899 E012 1.1066817 0.263369566 0.851210274 0.94728407 6 52994157 52994261 105 - 0.297 0.347 0.317
ENSG00000170899 E013 0.1176306 0.012239651 0.499965657   6 52994262 52994403 142 - 0.095 0.000 -11.495
ENSG00000170899 E014 0.0000000       6 52995071 52995248 178 -      
ENSG00000170899 E015 0.2352613 0.209112370 0.260104173   6 52995249 52995304 56 - 0.173 0.000 -12.495

Help

Please Click HERE to learn more details about the results from DEXseq.