ENSG00000171204

1 Isoform Switch

Summary Plot

Only the isoforms with fraction > 5% are shown below.

  • Note:

    • About the Coding Potential: Please check the spreadsheet in the “Results” tag to confirm the coding potential. The above figure only show the predicted coding potential. The “gene_biotype” in the result spreadsheet is from the database record. Therefore, if you find conflicts between “gene_biotype” and “codingPotential”, please trust the “gene_biotype”.

    • Notes on IDR and IDR_w_binding: As the prediction of Intrinsically Disordered Regions (IDR) and Intrinsically Disordered Binding Regions (IDBR) are done by two different tools we require two things to annotate the Intrinsically Disordered Binding Regions (IDBR). Firstly the IDBR (predicted by ANCHOR2) must be a region of at least 15 amino acids (after the smoothing). Secondly the fraction of the IDBR which overlaps the IDR predictions (done by IUPred3, again after smoothing) must be at least 80%. When that is the case the IDR type will be annotated as “IDR_w_binding_region” instead of just “IDR”. The current default parameters have not been rigorously tested and should be considered experimental.

    • For the function of any other domain, please Click HERE to search it through Pfam database.

Results

isoform_id gene_id condition_1 condition_2 gene_name gene_biotype iso_biotype gene_overall_mean gene_value_1 gene_value_2 gene_stderr_1 gene_stderr_2 gene_log2_fold_change iso_overall_mean iso_value_1 iso_value_2 iso_stderr_1 iso_stderr_2 iso_log2_fold_change IF_overall IF1 IF2 dIF isoform_switch_q_value gene_switch_q_value PTC codingPotential
ENST00000358867 ENSG00000171204 No_inf pgKDN_inf TMEM126B protein_coding protein_coding 37.77392 35.50167 42.62676 5.333368 2.847352 0.2638048 14.273675 11.608581 20.538777 2.9665841 1.7736111 0.8226187 0.36333333 0.313250 0.481750 0.168500 0.2388359605 0.0002466873 FALSE  
ENST00000393375 ENSG00000171204 No_inf pgKDN_inf TMEM126B protein_coding protein_coding 37.77392 35.50167 42.62676 5.333368 2.847352 0.2638048 3.973033 3.467544 2.646450 3.4675440 2.6464502 -0.3885691 0.13703333 0.140850 0.077200 -0.063650 1.0000000000 0.0002466873 FALSE  
ENST00000529197 ENSG00000171204 No_inf pgKDN_inf TMEM126B protein_coding nonsense_mediated_decay 37.77392 35.50167 42.62676 5.333368 2.847352 0.2638048 1.090855 3.272566 0.000000 3.2725655 0.0000000 -8.3586800 0.03885833 0.116575 0.000000 -0.116575 0.8489909132 0.0002466873 FALSE  
ENST00000530901 ENSG00000171204 No_inf pgKDN_inf TMEM126B protein_coding nonsense_mediated_decay 37.77392 35.50167 42.62676 5.333368 2.847352 0.2638048 1.326829 0.000000 2.611135 0.0000000 0.5819554 8.0340477 0.03657500 0.000000 0.062325 0.062325 0.0002466873 0.0002466873    
ENST00000531477 ENSG00000171204 No_inf pgKDN_inf TMEM126B protein_coding nonsense_mediated_decay 37.77392 35.50167 42.62676 5.333368 2.847352 0.2638048 2.211625 2.021656 2.189573 1.0323828 1.3904603 0.1145678 0.05642500 0.056050 0.048575 -0.007475 0.9074711169 0.0002466873 FALSE  
ENST00000531718 ENSG00000171204 No_inf pgKDN_inf TMEM126B protein_coding nonsense_mediated_decay 37.77392 35.50167 42.62676 5.333368 2.847352 0.2638048 10.110032 9.019322 11.228372 5.2114768 3.7994024 0.3157435 0.23689167 0.201950 0.247650 0.045700 0.8489909132 0.0002466873    
ENST00000534341 ENSG00000171204 No_inf pgKDN_inf TMEM126B protein_coding protein_coding 37.77392 35.50167 42.62676 5.333368 2.847352 0.2638048 2.700219 3.548422 1.329022 0.6064396 0.2163817 -1.4100585 0.07805833 0.107150 0.031125 -0.076025 0.2009761872 0.0002466873 FALSE  
  • Note:
    • The comparisons made can be identified as “from ‘condition_1’ to ‘condition_2’”, meaning ‘condition_1’ is considered the ground state and ‘condition_2’ the changed state. This also means that a positive dIF value indicates that the isoform usage is increased in ‘condition_2’ compared to ‘condition_1’. Since the ‘isoformFeatures’ entry is the most relevant part of the switchAnalyzeRlist object, the most-used standard methods have also been implemented to work directly on isoformFeatures.

Help

Please Click HERE to learn more details about the results of IsoformSwitchAnalyzeR.

2 Differential Exon Usage

Counts

All exons whithin this gene region are shown and numbering below.

Expression

All exons whithin this gene region are shown and numbering below.

Splicing

All exons whithin this gene region are shown and numbering below.

Transcripts

All isoforms whithin this gene region are shown below.

Results

groupID featureID exonBaseMean dispersion pvalue padj seqnames start end width strand pgKDN.inf No.inf log2fold_No.inf_pgKDN.inf
ENSG00000171204 E001 0.1271363 0.0123196624 0.53357101   11 85628573 85628592 20 + 0.000 0.096 9.063
ENSG00000171204 E002 0.2543986 0.0160731213 0.23943012   11 85628593 85628596 4 + 0.000 0.174 11.943
ENSG00000171204 E003 0.3731018 0.0166137940 0.57790242   11 85628597 85628601 5 + 0.095 0.174 1.016
ENSG00000171204 E004 0.9820640 0.0120664340 0.99007810 1.00000000 11 85628602 85628603 2 + 0.295 0.298 0.016
ENSG00000171204 E005 1.8266995 0.0079366714 0.45306781 0.72590138 11 85628604 85628604 1 + 0.504 0.394 -0.569
ENSG00000171204 E006 4.3780496 0.0044180278 0.19573917 0.47609796 11 85628605 85628618 14 + 0.803 0.648 -0.636
ENSG00000171204 E007 6.0802232 0.0098562577 0.11315737 0.35386112 11 85628619 85628629 11 + 0.932 0.754 -0.690
ENSG00000171204 E008 18.1989693 0.0008453123 0.38296409 0.66910542 11 85628630 85628688 59 + 1.311 1.255 -0.197
ENSG00000171204 E009 1.9541832 0.0084146440 0.63449473 0.84377293 11 85629132 85629203 72 + 0.504 0.435 -0.346
ENSG00000171204 E010 1.2248833 0.0103825027 0.98952183 1.00000000 11 85629204 85629262 59 + 0.346 0.348 0.016
ENSG00000171204 E011 18.3216931 0.0007692927 0.13633393 0.39274651 11 85631145 85631316 172 + 1.232 1.331 0.347
ENSG00000171204 E012 30.6955185 0.0006268161 0.50582253 0.76461269 11 85631687 85631808 122 + 1.517 1.485 -0.110
ENSG00000171204 E013 28.9009168 0.0006173586 0.94564300 0.98532339 11 85634086 85634176 91 + 1.473 1.478 0.016
ENSG00000171204 E014 24.5230909 0.0006816374 0.61079421 0.83068427 11 85634177 85634279 103 + 1.391 1.421 0.103
ENSG00000171204 E015 3.5795809 0.0044127553 0.34152429 0.63304708 11 85634280 85635087 808 + 0.593 0.715 0.519
ENSG00000171204 E016 23.2426725 0.0006369292 0.69658520 0.87609603 11 85635667 85635778 112 + 1.395 1.374 -0.075
ENSG00000171204 E017 4.5994718 0.0033545273 0.01180802 0.08967247 11 85635779 85636045 267 + 0.566 0.869 1.257
ENSG00000171204 E018 52.6614793 0.0003296719 0.99614268 1.00000000 11 85636046 85636539 494 + 1.729 1.730 0.003

Help

Please Click HERE to learn more details about the results from DEXseq.