ENSG00000171241

1 Isoform Switch

Summary Plot

Only the isoforms with fraction > 5% are shown below.

  • Note:

    • About the Coding Potential: Please check the spreadsheet in the “Results” tag to confirm the coding potential. The above figure only show the predicted coding potential. The “gene_biotype” in the result spreadsheet is from the database record. Therefore, if you find conflicts between “gene_biotype” and “codingPotential”, please trust the “gene_biotype”.

    • Notes on IDR and IDR_w_binding: As the prediction of Intrinsically Disordered Regions (IDR) and Intrinsically Disordered Binding Regions (IDBR) are done by two different tools we require two things to annotate the Intrinsically Disordered Binding Regions (IDBR). Firstly the IDBR (predicted by ANCHOR2) must be a region of at least 15 amino acids (after the smoothing). Secondly the fraction of the IDBR which overlaps the IDR predictions (done by IUPred3, again after smoothing) must be at least 80%. When that is the case the IDR type will be annotated as “IDR_w_binding_region” instead of just “IDR”. The current default parameters have not been rigorously tested and should be considered experimental.

    • For the function of any other domain, please Click HERE to search it through Pfam database.

Results

isoform_id gene_id condition_1 condition_2 gene_name gene_biotype iso_biotype gene_overall_mean gene_value_1 gene_value_2 gene_stderr_1 gene_stderr_2 gene_log2_fold_change iso_overall_mean iso_value_1 iso_value_2 iso_stderr_1 iso_stderr_2 iso_log2_fold_change IF_overall IF1 IF2 dIF isoform_switch_q_value gene_switch_q_value PTC codingPotential
ENST00000303383 ENSG00000171241 No_inf pgKDN_inf SHCBP1 protein_coding protein_coding 13.11572 7.556897 16.91302 0.596282 1.340677 1.161213 3.8686701 4.691938 3.4088577 0.7945421 1.9681304 -0.4597413 0.35193333 0.632275 0.220700 -0.411575 0.34550122 0.03818245 FALSE TRUE
ENST00000564272 ENSG00000171241 No_inf pgKDN_inf SHCBP1 protein_coding protein_coding_CDS_not_defined 13.11572 7.556897 16.91302 0.596282 1.340677 1.161213 0.6552151 1.066052 0.4802733 0.4422055 0.1602310 -1.1340897 0.06374167 0.130500 0.030850 -0.099650 0.51983764 0.03818245   FALSE
ENST00000566016 ENSG00000171241 No_inf pgKDN_inf SHCBP1 protein_coding retained_intron 13.11572 7.556897 16.91302 0.596282 1.340677 1.161213 0.5669716 0.104535 1.5963799 0.1045350 0.5671688 3.8099523 0.03505000 0.014075 0.091075 0.077000 0.51046804 0.03818245 FALSE TRUE
ENST00000567698 ENSG00000171241 No_inf pgKDN_inf SHCBP1 protein_coding retained_intron 13.11572 7.556897 16.91302 0.596282 1.340677 1.161213 0.5333801 0.000000 0.7850020 0.0000000 0.7850020 6.3128866 0.03287500 0.000000 0.051450 0.051450 0.96573760 0.03818245   FALSE
ENST00000569702 ENSG00000171241 No_inf pgKDN_inf SHCBP1 protein_coding protein_coding 13.11572 7.556897 16.91302 0.596282 1.340677 1.161213 0.5380357 0.000000 1.6141071 0.0000000 1.6141071 7.3435030 0.02571667 0.000000 0.077150 0.077150 0.94090040 0.03818245 FALSE FALSE
MSTRG.11111.1 ENSG00000171241 No_inf pgKDN_inf SHCBP1 protein_coding   13.11572 7.556897 16.91302 0.596282 1.340677 1.161213 5.1346144 0.000000 6.3215077 0.0000000 2.5669651 9.3064053 0.33519167 0.000000 0.356625 0.356625 0.03818245 0.03818245 FALSE TRUE
MSTRG.11111.3 ENSG00000171241 No_inf pgKDN_inf SHCBP1 protein_coding   13.11572 7.556897 16.91302 0.596282 1.340677 1.161213 1.7407028 1.694371 2.4724843 0.9798243 1.4302025 0.5425449 0.15048333 0.223150 0.157150 -0.066000 0.96337607 0.03818245 FALSE TRUE
  • Note:
    • The comparisons made can be identified as “from ‘condition_1’ to ‘condition_2’”, meaning ‘condition_1’ is considered the ground state and ‘condition_2’ the changed state. This also means that a positive dIF value indicates that the isoform usage is increased in ‘condition_2’ compared to ‘condition_1’. Since the ‘isoformFeatures’ entry is the most relevant part of the switchAnalyzeRlist object, the most-used standard methods have also been implemented to work directly on isoformFeatures.

Help

Please Click HERE to learn more details about the results of IsoformSwitchAnalyzeR.

2 Differential Exon Usage

Counts

All exons whithin this gene region are shown and numbering below.

Expression

All exons whithin this gene region are shown and numbering below.

Splicing

All exons whithin this gene region are shown and numbering below.

Transcripts

All isoforms whithin this gene region are shown below.

Results

groupID featureID exonBaseMean dispersion pvalue padj seqnames start end width strand pgKDN.inf No.inf log2fold_No.inf_pgKDN.inf
ENSG00000171241 E001 0.0000000       16 46578591 46578700 110 -      
ENSG00000171241 E002 115.3117820 0.0001570365 0.0005677171 0.009640824 16 46578701 46581912 3212 - 2.017 2.100 0.276
ENSG00000171241 E003 21.6172207 0.0025670308 0.2756977443 0.569262498 16 46581913 46582054 142 - 1.311 1.383 0.250
ENSG00000171241 E004 17.1330278 0.0077554171 0.4355008309 0.712263148 16 46583516 46583657 142 - 1.219 1.281 0.221
ENSG00000171241 E005 13.5830362 0.0010182381 0.6885910985 0.871761161 16 46584003 46584089 87 - 1.136 1.169 0.117
ENSG00000171241 E006 0.0000000       16 46584090 46584253 164 -      
ENSG00000171241 E007 13.3072381 0.0087106755 0.9608018749 0.991223521 16 46595552 46595623 72 - 1.142 1.138 -0.012
ENSG00000171241 E008 8.4348127 0.0197009076 0.4507192426 0.723894215 16 46595624 46595670 47 - 0.989 0.905 -0.312
ENSG00000171241 E009 14.0120011 0.0010368355 0.5024642631 0.762132504 16 46599831 46599928 98 - 1.179 1.128 -0.185
ENSG00000171241 E010 8.1030702 0.0016598993 0.7327988370 0.893755738 16 46599929 46599962 34 - 0.956 0.923 -0.123
ENSG00000171241 E011 7.6194554 0.0037001545 0.8046007756 0.927647247 16 46603539 46603593 55 - 0.929 0.906 -0.090
ENSG00000171241 E012 10.1103452 0.0015607097 0.0889674429 0.309532323 16 46603594 46603659 66 - 1.082 0.923 -0.585
ENSG00000171241 E013 0.3644776 0.0165478059 1.0000000000   16 46603660 46603974 315 - 0.133 0.126 -0.090
ENSG00000171241 E014 7.9632243 0.0021110791 0.2981264828 0.591123625 16 46603975 46603989 15 - 0.973 0.868 -0.397
ENSG00000171241 E015 19.2127081 0.0007180334 0.3610517280 0.650660381 16 46603990 46604143 154 - 1.311 1.250 -0.215
ENSG00000171241 E016 0.0000000       16 46604144 46604227 84 -      
ENSG00000171241 E017 24.1396432 0.0005935122 0.4724881596 0.739714845 16 46604228 46604461 234 - 1.368 1.412 0.153
ENSG00000171241 E018 11.7004126 0.0012152895 0.2091945644 0.493444309 16 46608297 46608389 93 - 1.125 1.017 -0.392
ENSG00000171241 E019 14.1748992 0.0021125810 0.0050384795 0.049898155 16 46615946 46616154 209 - 1.237 1.003 -0.843
ENSG00000171241 E020 9.7240253 0.0014741108 0.0264882200 0.150806402 16 46617634 46617749 116 - 1.082 0.868 -0.797
ENSG00000171241 E021 10.8402479 0.0014100093 0.1529636927 0.417270009 16 46618205 46618372 168 - 1.101 0.973 -0.469
ENSG00000171241 E022 1.3703027 0.0128261429 0.0116820286 0.089029042 16 46620466 46620900 435 - 0.186 0.566 2.325
ENSG00000171241 E023 6.6070144 0.0030332384 0.1384990499 0.395862116 16 46621257 46621412 156 - 0.920 0.756 -0.641
ENSG00000171241 E024 0.3811266 0.0384989743 0.0293618417   16 46621679 46621719 41 - 0.000 0.302 10.972

Help

Please Click HERE to learn more details about the results from DEXseq.