ENSG00000171316

1 Isoform Switch

Summary Plot

Only the isoforms with fraction > 5% are shown below.

  • Note:

    • About the Coding Potential: Please check the spreadsheet in the “Results” tag to confirm the coding potential. The above figure only show the predicted coding potential. The “gene_biotype” in the result spreadsheet is from the database record. Therefore, if you find conflicts between “gene_biotype” and “codingPotential”, please trust the “gene_biotype”.

    • Notes on IDR and IDR_w_binding: As the prediction of Intrinsically Disordered Regions (IDR) and Intrinsically Disordered Binding Regions (IDBR) are done by two different tools we require two things to annotate the Intrinsically Disordered Binding Regions (IDBR). Firstly the IDBR (predicted by ANCHOR2) must be a region of at least 15 amino acids (after the smoothing). Secondly the fraction of the IDBR which overlaps the IDR predictions (done by IUPred3, again after smoothing) must be at least 80%. When that is the case the IDR type will be annotated as “IDR_w_binding_region” instead of just “IDR”. The current default parameters have not been rigorously tested and should be considered experimental.

    • For the function of any other domain, please Click HERE to search it through Pfam database.

Results

isoform_id gene_id condition_1 condition_2 gene_name gene_biotype iso_biotype gene_overall_mean gene_value_1 gene_value_2 gene_stderr_1 gene_stderr_2 gene_log2_fold_change iso_overall_mean iso_value_1 iso_value_2 iso_stderr_1 iso_stderr_2 iso_log2_fold_change IF_overall IF1 IF2 dIF isoform_switch_q_value gene_switch_q_value PTC codingPotential
ENST00000423902 ENSG00000171316 No_inf pgKDN_inf CHD7 protein_coding protein_coding 8.425189 8.94003 8.663222 0.2693246 0.3044341 -0.04532448 4.6478121 4.0076596 5.488014 0.7520065 0.1995226 0.45255527 0.55478333 0.449950 0.636250 0.186300 0.58287477 0.04045617 FALSE TRUE
ENST00000528280 ENSG00000171316 No_inf pgKDN_inf CHD7 protein_coding retained_intron 8.425189 8.94003 8.663222 0.2693246 0.3044341 -0.04532448 0.4780169 0.7058027 0.728248 0.7058027 0.7282480 0.04454359 0.05216667 0.077375 0.079125 0.001750 1.00000000 0.04045617 FALSE TRUE
ENST00000695850 ENSG00000171316 No_inf pgKDN_inf CHD7 protein_coding protein_coding_CDS_not_defined 8.425189 8.94003 8.663222 0.2693246 0.3044341 -0.04532448 0.5006011 1.2689551 0.000000 0.5440410 0.0000000 -6.99882181 0.05835000 0.143850 0.000000 -0.143850 0.10575034 0.04045617 FALSE TRUE
ENST00000695852 ENSG00000171316 No_inf pgKDN_inf CHD7 protein_coding retained_intron 8.425189 8.94003 8.663222 0.2693246 0.3044341 -0.04532448 0.2271702 0.6815107 0.000000 0.3999841 0.0000000 -6.11167971 0.02455833 0.073675 0.000000 -0.073675 0.50455496 0.04045617 FALSE TRUE
MSTRG.27722.12 ENSG00000171316 No_inf pgKDN_inf CHD7 protein_coding   8.425189 8.94003 8.663222 0.2693246 0.3044341 -0.04532448 1.0019010 0.0000000 1.863311 0.0000000 0.6797868 7.54944693 0.11864167 0.000000 0.217525 0.217525 0.04045617 0.04045617 FALSE TRUE
MSTRG.27722.5 ENSG00000171316 No_inf pgKDN_inf CHD7 protein_coding   8.425189 8.94003 8.663222 0.2693246 0.3044341 -0.04532448 0.8115689 1.3323494 0.000000 0.8569208 0.0000000 -7.06861644 0.10163333 0.149475 0.000000 -0.149475 0.19477338 0.04045617 FALSE TRUE
  • Note:
    • The comparisons made can be identified as “from ‘condition_1’ to ‘condition_2’”, meaning ‘condition_1’ is considered the ground state and ‘condition_2’ the changed state. This also means that a positive dIF value indicates that the isoform usage is increased in ‘condition_2’ compared to ‘condition_1’. Since the ‘isoformFeatures’ entry is the most relevant part of the switchAnalyzeRlist object, the most-used standard methods have also been implemented to work directly on isoformFeatures.

Help

Please Click HERE to learn more details about the results of IsoformSwitchAnalyzeR.

2 Differential Exon Usage

Counts

All exons whithin this gene region are shown and numbering below.

Expression

All exons whithin this gene region are shown and numbering below.

Splicing

All exons whithin this gene region are shown and numbering below.

Transcripts

All isoforms whithin this gene region are shown below.

Results

groupID featureID exonBaseMean dispersion pvalue padj seqnames start end width strand pgKDN.inf No.inf log2fold_No.inf_pgKDN.inf
ENSG00000171316 E001 0.0000000       8 60678740 60678743 4 +      
ENSG00000171316 E002 0.5085150 0.0159095536 0.055932693 0.23566102 8 60678744 60678800 57 + 0.000 0.286 11.220
ENSG00000171316 E003 4.8951121 0.0038339379 0.544921378 0.79108202 8 60678801 60679082 282 + 0.806 0.735 -0.282
ENSG00000171316 E004 0.0000000       8 60679564 60679791 228 +      
ENSG00000171316 E005 0.1268540 0.0123176957 0.590660885   8 60679863 60680238 376 + 0.000 0.091 11.959
ENSG00000171316 E006 2.3667250 0.1610006669 0.142050247 0.40097503 8 60741259 60741364 106 + 0.359 0.630 1.346
ENSG00000171316 E007 1.4791234 0.0114812591 0.681555778 0.86827810 8 60741365 60741432 68 + 0.359 0.421 0.347
ENSG00000171316 E008 7.5835146 0.0168417230 0.423465136 0.70274365 8 60741433 60741854 422 + 0.977 0.890 -0.325
ENSG00000171316 E009 1.2441752 0.0114344930 0.261568404 0.55432356 8 60741855 60741885 31 + 0.248 0.421 1.084
ENSG00000171316 E010 23.1313060 0.0005901281 0.261638165 0.55432520 8 60741886 60742819 934 + 1.343 1.411 0.232
ENSG00000171316 E011 8.8432636 0.0028795070 0.759993266 0.90594490 8 60742820 60743031 212 + 0.976 1.004 0.103
ENSG00000171316 E012 4.6903862 0.0029379925 0.314357125 0.60741766 8 60743032 60743097 66 + 0.686 0.804 0.479
ENSG00000171316 E013 4.3872737 0.0038751552 0.349612842 0.63993185 8 60781000 60781050 51 + 0.788 0.675 -0.460
ENSG00000171316 E014 12.4001761 0.0519535299 0.741214616 0.89735739 8 60781051 60781258 208 + 1.107 1.141 0.120
ENSG00000171316 E015 16.7208465 0.0008403066 0.405435530 0.68821829 8 60781259 60781430 172 + 1.215 1.273 0.203
ENSG00000171316 E016 10.8100110 0.0013735597 0.679433315 0.86755265 8 60794986 60795127 142 + 1.052 1.086 0.125
ENSG00000171316 E017 5.8056579 0.0025661252 0.200229918 0.48225787 8 60800388 60800525 138 + 0.750 0.890 0.550
ENSG00000171316 E018 0.0000000       8 60800526 60800526 1 +      
ENSG00000171316 E019 5.3507727 0.0025563711 0.008633745 0.07284925 8 60801528 60801593 66 + 0.611 0.916 1.231
ENSG00000171316 E020 2.8569165 0.0048054900 0.096215561 0.32305859 8 60808217 60808219 3 + 0.447 0.675 1.055
ENSG00000171316 E021 5.1849602 0.0039712008 0.218039314 0.50447138 8 60808220 60808272 53 + 0.708 0.849 0.563
ENSG00000171316 E022 0.6261159 0.0149942653 0.207298549 0.49095156 8 60808273 60809651 1379 + 0.099 0.286 1.862
ENSG00000171316 E023 9.4889992 0.0015155007 0.284496250 0.57820518 8 60816387 60816501 115 + 0.965 1.061 0.354
ENSG00000171316 E024 7.0769927 0.0020307817 0.256004937 0.54804535 8 60820007 60820090 84 + 0.965 0.849 -0.438
ENSG00000171316 E025 8.8224034 0.0017130879 0.873675359 0.95691722 8 60821790 60821927 138 + 0.999 0.984 -0.058
ENSG00000171316 E026 7.6440255 0.0229458352 0.438618938 0.71471777 8 60822024 60822145 122 + 0.885 0.973 0.332
ENSG00000171316 E027 7.3685774 0.0140082288 0.894382709 0.96502983 8 60822503 60822746 244 + 0.913 0.928 0.055
ENSG00000171316 E028 6.4684317 0.0758694853 0.565058637 0.80405356 8 60823840 60824016 177 + 0.927 0.820 -0.411
ENSG00000171316 E029 0.3813786 0.0319921961 0.124777061   8 60824017 60825415 1399 + 0.000 0.230 13.386
ENSG00000171316 E030 5.0235806 0.0213207342 0.900471497 0.96768211 8 60828663 60828806 144 + 0.788 0.771 -0.068
ENSG00000171316 E031 8.5457262 0.0016072445 0.270333373 0.56398577 8 60830322 60830577 256 + 1.032 0.928 -0.386
ENSG00000171316 E032 7.6926563 0.0018544320 0.320120060 0.61296453 8 60836073 60836283 211 + 0.988 0.890 -0.367
ENSG00000171316 E033 6.2580902 0.0021833513 0.931838583 0.98013197 8 60836817 60837012 196 + 0.855 0.863 0.032
ENSG00000171316 E034 4.8103440 0.0030291291 0.410312056 0.69215280 8 60837668 60837835 168 + 0.708 0.804 0.386
ENSG00000171316 E035 5.7112445 0.0069546431 0.061246183 0.24851427 8 60838076 60838255 180 + 0.927 0.716 -0.826
ENSG00000171316 E036 1.5631422 0.0125822543 0.033746466 0.17482297 8 60841644 60841664 21 + 0.552 0.230 -1.875
ENSG00000171316 E037 2.6891165 0.0058426421 0.522799564 0.77623322 8 60841665 60841754 90 + 0.611 0.523 -0.401
ENSG00000171316 E038 7.7081327 0.0017383936 0.621439198 0.83668781 8 60841847 60842052 206 + 0.965 0.916 -0.184
ENSG00000171316 E039 7.6950935 0.0107462540 0.351258195 0.64158654 8 60844864 60845063 200 + 0.988 0.890 -0.367
ENSG00000171316 E040 4.8794208 0.0533844125 0.454555790 0.72721915 8 60845250 60845409 160 + 0.823 0.716 -0.428
ENSG00000171316 E041 4.6134396 0.0049255712 0.059302710 0.24433860 8 60848515 60848604 90 + 0.855 0.630 -0.916
ENSG00000171316 E042 5.8239292 0.0105102468 0.024868613 0.14495448 8 60849051 60849154 104 + 0.952 0.696 -1.005
ENSG00000171316 E043 6.3437740 0.0022222959 0.245437711 0.53595513 8 60850493 60850622 130 + 0.927 0.804 -0.472
ENSG00000171316 E044 0.0000000       8 60850737 60850761 25 +      
ENSG00000171316 E045 5.5674675 0.0025658976 0.103671762 0.33654854 8 60851032 60851104 73 + 0.708 0.890 0.720
ENSG00000171316 E046 5.2684448 0.0027602851 0.879688481 0.95942824 8 60851262 60851319 58 + 0.806 0.788 -0.071
ENSG00000171316 E047 11.4525835 0.0079494769 0.116584890 0.36016956 8 60852019 60852247 229 + 1.165 1.024 -0.508
ENSG00000171316 E048 11.8599675 0.0325813598 0.720857051 0.88754033 8 60852498 60852706 209 + 1.133 1.086 -0.167
ENSG00000171316 E049 27.7986997 0.0073544935 0.026316903 0.15030984 8 60852829 60853500 672 + 1.530 1.386 -0.494
ENSG00000171316 E050 2.6858426 0.0054686726 0.523157024 0.77663356 8 60854363 60854365 3 + 0.611 0.523 -0.401
ENSG00000171316 E051 8.9869202 0.0176058972 0.079808089 0.28998751 8 60854366 60854523 158 + 1.090 0.903 -0.690
ENSG00000171316 E052 0.0000000       8 60855093 60855209 117 +      
ENSG00000171316 E053 0.1271363 0.0123338591 0.590692820   8 60855571 60855682 112 + 0.000 0.091 11.959
ENSG00000171316 E054 12.5641722 0.0010945682 0.119569390 0.36552097 8 60855975 60856202 228 + 1.194 1.069 -0.447
ENSG00000171316 E055 14.2082169 0.0010483287 0.751030089 0.90179419 8 60856445 60856856 412 + 1.194 1.169 -0.088
ENSG00000171316 E056 3.4228864 0.0857129548 0.928530009 0.97885768 8 60856857 60856888 32 + 0.662 0.630 -0.137
ENSG00000171316 E057 2.9407131 0.2239334397 0.715071873 0.88516609 8 60860904 60860915 12 + 0.582 0.606 0.105
ENSG00000171316 E058 12.6266629 0.0273986912 0.951444021 0.98778021 8 60860916 60861125 210 + 1.133 1.134 0.003
ENSG00000171316 E059 1.7220621 0.0084323478 0.721177122 0.88767064 8 60861126 60861943 818 + 0.405 0.457 0.277
ENSG00000171316 E060 0.6244167 0.0150205968 0.206977087 0.49059667 8 60861944 60862195 252 + 0.099 0.286 1.862
ENSG00000171316 E061 5.9310362 0.0040090157 0.163129939 0.43177358 8 60862196 60862228 33 + 0.750 0.903 0.599
ENSG00000171316 E062 8.4044757 0.0021526166 0.072497875 0.27326161 8 60862229 60862336 108 + 0.870 1.043 0.644
ENSG00000171316 E063 0.2363338 0.0157325576 0.211774510   8 60862337 60862530 194 + 0.180 0.000 -13.775
ENSG00000171316 E064 0.0000000       8 60862531 60862547 17 +      
ENSG00000171316 E065 3.7164418 0.0038679591 0.115452317 0.35819822 8 60862548 60862549 2 + 0.552 0.753 0.862
ENSG00000171316 E066 8.6180474 0.0016252291 0.422303576 0.70157828 8 60862550 60862652 103 + 0.940 1.014 0.277
ENSG00000171316 E067 4.0935731 0.0453937972 0.085864817 0.30341565 8 60862653 60864935 2283 + 0.552 0.804 1.064
ENSG00000171316 E068 0.7324829 0.0360813385 0.913222127 0.97247122 8 60864936 60865015 80 + 0.248 0.230 -0.138
ENSG00000171316 E069 133.7389908 0.0001854864 0.214001808 0.49918212 8 60865016 60868028 3013 + 2.113 2.141 0.093

Help

Please Click HERE to learn more details about the results from DEXseq.