ENSG00000171456

1 Isoform Switch

Summary Plot

Only the isoforms with fraction > 5% are shown below.

  • Note:

    • About the Coding Potential: Please check the spreadsheet in the “Results” tag to confirm the coding potential. The above figure only show the predicted coding potential. The “gene_biotype” in the result spreadsheet is from the database record. Therefore, if you find conflicts between “gene_biotype” and “codingPotential”, please trust the “gene_biotype”.

    • Notes on IDR and IDR_w_binding: As the prediction of Intrinsically Disordered Regions (IDR) and Intrinsically Disordered Binding Regions (IDBR) are done by two different tools we require two things to annotate the Intrinsically Disordered Binding Regions (IDBR). Firstly the IDBR (predicted by ANCHOR2) must be a region of at least 15 amino acids (after the smoothing). Secondly the fraction of the IDBR which overlaps the IDR predictions (done by IUPred3, again after smoothing) must be at least 80%. When that is the case the IDR type will be annotated as “IDR_w_binding_region” instead of just “IDR”. The current default parameters have not been rigorously tested and should be considered experimental.

    • For the function of any other domain, please Click HERE to search it through Pfam database.

Results

isoform_id gene_id condition_1 condition_2 gene_name gene_biotype iso_biotype gene_overall_mean gene_value_1 gene_value_2 gene_stderr_1 gene_stderr_2 gene_log2_fold_change iso_overall_mean iso_value_1 iso_value_2 iso_stderr_1 iso_stderr_2 iso_log2_fold_change IF_overall IF1 IF2 dIF isoform_switch_q_value gene_switch_q_value PTC codingPotential
ENST00000306058 ENSG00000171456 No_inf pgKDN_inf ASXL1 protein_coding protein_coding 16.34761 19.95912 14.15112 0.6541124 1.130898 -0.4958359 1.7322376 0.0000000 5.1967129 0.00000000 0.5034432 9.0242291 0.12508333 0.000000 0.375250 0.375250 1.420451e-10 1.420451e-10 FALSE TRUE
ENST00000375687 ENSG00000171456 No_inf pgKDN_inf ASXL1 protein_coding protein_coding 16.34761 19.95912 14.15112 0.6541124 1.130898 -0.4958359 4.6823104 5.6455065 2.4055579 1.05762817 0.9007831 -1.2272998 0.28543333 0.286575 0.174725 -0.111850 7.710345e-01 1.420451e-10 FALSE TRUE
ENST00000644615 ENSG00000171456 No_inf pgKDN_inf ASXL1 protein_coding retained_intron 16.34761 19.95912 14.15112 0.6541124 1.130898 -0.4958359 3.1399092 5.1394267 1.2595449 0.50781870 1.2595449 -2.0201004 0.17396667 0.256325 0.075450 -0.180875 1.080971e-01 1.420451e-10 FALSE FALSE
ENST00000645688 ENSG00000171456 No_inf pgKDN_inf ASXL1 protein_coding protein_coding 16.34761 19.95912 14.15112 0.6541124 1.130898 -0.4958359 0.2445335 0.0000000 0.7336005 0.00000000 0.2509929 6.2164558 0.01692500 0.000000 0.050775 0.050775 6.223584e-02 1.420451e-10   FALSE
ENST00000646367 ENSG00000171456 No_inf pgKDN_inf ASXL1 protein_coding protein_coding 16.34761 19.95912 14.15112 0.6541124 1.130898 -0.4958359 0.6029379 0.0000000 1.1859070 0.00000000 0.5801998 6.9019614 0.04235000 0.000000 0.088250 0.088250 1.130072e-01 1.420451e-10   FALSE
ENST00000647223 ENSG00000171456 No_inf pgKDN_inf ASXL1 protein_coding retained_intron 16.34761 19.95912 14.15112 0.6541124 1.130898 -0.4958359 1.2054149 1.4548322 0.8636958 0.09030771 0.0806255 -0.7455324 0.07383333 0.073500 0.061400 -0.012100 9.215489e-01 1.420451e-10 FALSE TRUE
MSTRG.18136.28 ENSG00000171456 No_inf pgKDN_inf ASXL1 protein_coding   16.34761 19.95912 14.15112 0.6541124 1.130898 -0.4958359 2.5199773 5.2139760 0.8391382 1.78181615 0.8391382 -2.6210770 0.14123333 0.258750 0.054500 -0.204250 3.301624e-01 1.420451e-10 FALSE TRUE
MSTRG.18136.6 ENSG00000171456 No_inf pgKDN_inf ASXL1 protein_coding   16.34761 19.95912 14.15112 0.6541124 1.130898 -0.4958359 0.8323619 0.9812023 0.8760870 0.57327007 0.5062872 -0.1617312 0.05535000 0.048225 0.063625 0.015400 9.839319e-01 1.420451e-10 FALSE TRUE
  • Note:
    • The comparisons made can be identified as “from ‘condition_1’ to ‘condition_2’”, meaning ‘condition_1’ is considered the ground state and ‘condition_2’ the changed state. This also means that a positive dIF value indicates that the isoform usage is increased in ‘condition_2’ compared to ‘condition_1’. Since the ‘isoformFeatures’ entry is the most relevant part of the switchAnalyzeRlist object, the most-used standard methods have also been implemented to work directly on isoformFeatures.

Help

Please Click HERE to learn more details about the results of IsoformSwitchAnalyzeR.

2 Differential Exon Usage

Counts

All exons whithin this gene region are shown and numbering below.

Expression

All exons whithin this gene region are shown and numbering below.

Splicing

All exons whithin this gene region are shown and numbering below.

Transcripts

All isoforms whithin this gene region are shown below.

Results

groupID featureID exonBaseMean dispersion pvalue padj seqnames start end width strand pgKDN.inf No.inf log2fold_No.inf_pgKDN.inf
ENSG00000171456 E001 0.1186381 0.0118658064 0.351256650   20 32358330 32358330 1 + 0.114 0.000 -11.810
ENSG00000171456 E002 0.1186381 0.0118658064 0.351256650   20 32358331 32358331 1 + 0.114 0.000 -13.975
ENSG00000171456 E003 0.4996084 0.0303502047 0.559467327   20 32358332 32358343 12 + 0.114 0.203 0.990
ENSG00000171456 E004 0.6267447 0.0149816329 0.356920091 0.64668976 20 32358344 32358348 5 + 0.114 0.254 1.405
ENSG00000171456 E005 0.8725191 0.0348420165 0.543963389 0.79061953 20 32358349 32358358 10 + 0.205 0.300 0.727
ENSG00000171456 E006 1.2523872 0.0110618567 0.183186361 0.45989728 20 32358359 32358390 32 + 0.205 0.414 1.405
ENSG00000171456 E007 1.4950194 0.0087229215 0.282618671 0.57624208 20 32358391 32358412 22 + 0.279 0.446 0.990
ENSG00000171456 E008 2.4767364 0.0054374242 0.657037739 0.85649619 20 32358413 32358542 130 + 0.492 0.555 0.299
ENSG00000171456 E009 1.9687558 0.0069352188 0.755476185 0.90360806 20 32358543 32358595 53 + 0.492 0.446 -0.232
ENSG00000171456 E010 3.1993021 0.0045748004 0.801911788 0.92610246 20 32358596 32358763 168 + 0.634 0.601 -0.147
ENSG00000171456 E011 3.9088402 0.0037100271 0.134226503 0.38938104 20 32358764 32358832 69 + 0.786 0.601 -0.775
ENSG00000171456 E012 0.2536433 0.0160881599 0.419255315   20 32358966 32359064 99 + 0.000 0.146 13.332
ENSG00000171456 E013 0.1265070 0.0124381168 0.825158704   20 32359065 32359087 23 + 0.000 0.079 12.401
ENSG00000171456 E014 0.0000000       20 32359088 32359109 22 +      
ENSG00000171456 E015 0.0000000       20 32359110 32359236 127 +      
ENSG00000171456 E016 0.2536433 0.0160881599 0.419255315   20 32359237 32359334 98 + 0.000 0.146 13.332
ENSG00000171456 E017 0.4911106 0.0158790973 0.684360189   20 32359335 32359564 230 + 0.205 0.146 -0.595
ENSG00000171456 E018 0.3802764 0.0382063209 0.214512540   20 32359565 32359642 78 + 0.000 0.203 13.825
ENSG00000171456 E019 0.4886562 0.1150137079 0.694539668   20 32359643 32359746 104 + 0.205 0.146 -0.595
ENSG00000171456 E020 0.2340080 0.2556909020 0.175679510   20 32359747 32359791 45 + 0.204 0.000 -14.516
ENSG00000171456 E021 0.3709943 0.0167153892 0.876025446   20 32359792 32359851 60 + 0.114 0.146 0.406
ENSG00000171456 E022 0.3808443 0.0310003533 0.213533168   20 32360017 32360347 331 + 0.000 0.203 13.838
ENSG00000171456 E023 1.0970865 0.0109732929 0.347909163 0.63845297 20 32360348 32360586 239 + 0.399 0.254 -0.916
ENSG00000171456 E024 0.4804741 0.0154144205 0.160479862   20 32360634 32360709 76 + 0.279 0.079 -2.179
ENSG00000171456 E025 0.2373413 0.0156760476 0.130736719   20 32360710 32360793 84 + 0.205 0.000 -14.895
ENSG00000171456 E026 0.1186381 0.0118658064 0.351256650   20 32360794 32360806 13 + 0.114 0.000 -13.975
ENSG00000171456 E027 6.2939434 0.0246792198 0.954737872 0.98899180 20 32366384 32366466 83 + 0.846 0.856 0.038
ENSG00000171456 E028 0.2441403 0.0164649387 0.749230160   20 32366467 32366467 1 + 0.114 0.079 -0.594
ENSG00000171456 E029 3.2362528 0.0059247990 0.172661864 0.44548149 20 32367727 32367729 3 + 0.492 0.680 0.846
ENSG00000171456 E030 0.0000000       20 32369013 32369014 2 +      
ENSG00000171456 E031 6.1419088 0.0022850049 0.382571536 0.66883673 20 32369015 32369123 109 + 0.899 0.805 -0.363
ENSG00000171456 E032 0.2459004 0.0165081363 0.749062744   20 32371778 32371779 2 + 0.114 0.079 -0.595
ENSG00000171456 E033 0.8528842 0.0144365862 0.362857435 0.65192034 20 32371780 32371874 95 + 0.343 0.203 -1.010
ENSG00000171456 E034 1.4349676 0.0271515937 0.002765512 0.03247444 20 32372164 32372553 390 + 0.603 0.146 -2.917
ENSG00000171456 E035 0.8883830 0.0121671283 0.018359417 0.11976255 20 32427072 32428127 1056 + 0.000 0.379 14.943
ENSG00000171456 E036 2.8397669 0.0049423799 0.942684512 0.98412031 20 32428128 32428171 44 + 0.569 0.578 0.043
ENSG00000171456 E037 3.2992999 0.1604469288 0.287730318 0.58127131 20 32428172 32428248 77 + 0.742 0.530 -0.917
ENSG00000171456 E038 0.2448930 0.0168743044 0.748433736   20 32428249 32428324 76 + 0.114 0.079 -0.595
ENSG00000171456 E039 6.0154501 0.1251888392 0.352517780 0.64255953 20 32428325 32428422 98 + 0.915 0.777 -0.536
ENSG00000171456 E040 0.1265070 0.0124381168 0.825158704   20 32428764 32429206 443 + 0.000 0.079 12.401
ENSG00000171456 E041 0.3804973 0.0159303133 0.210371923   20 32429207 32429337 131 + 0.000 0.203 13.867
ENSG00000171456 E042 9.0552424 0.0015454833 0.046872322 0.21266688 20 32429338 32429431 94 + 1.094 0.912 -0.673
ENSG00000171456 E043 10.4581396 0.0013346348 0.016864982 0.11326060 20 32429432 32429739 308 + 0.899 1.119 0.813
ENSG00000171456 E044 4.4706769 0.0032937364 0.249782302 0.54077387 20 32429740 32429881 142 + 0.634 0.777 0.590
ENSG00000171456 E045 2.1227109 0.0068767475 0.158499802 0.42555398 20 32429882 32429900 19 + 0.343 0.555 1.106
ENSG00000171456 E046 10.5594538 0.0080954793 0.237453257 0.52646567 20 32429901 32430053 153 + 1.115 1.007 -0.393
ENSG00000171456 E047 9.6806135 0.0023845259 0.158280279 0.42519112 20 32430054 32430861 808 + 0.930 1.063 0.490
ENSG00000171456 E048 3.4584616 0.1382198933 0.995738007 1.00000000 20 32430862 32431176 315 + 0.634 0.642 0.033
ENSG00000171456 E049 2.0851342 0.0067538277 0.554058546 0.79697543 20 32431177 32431320 144 + 0.532 0.446 -0.425
ENSG00000171456 E050 10.7971522 0.0012804483 0.138606418 0.39589041 20 32431321 32431484 164 + 0.974 1.106 0.481
ENSG00000171456 E051 0.0000000       20 32431556 32431582 27 +      
ENSG00000171456 E052 5.8317561 0.0390584908 0.364067590 0.65277997 20 32431583 32431679 97 + 0.741 0.868 0.498
ENSG00000171456 E053 0.1186381 0.0118658064 0.351256650   20 32432359 32432879 521 + 0.114 0.000 -13.975
ENSG00000171456 E054 9.8536524 0.0089351194 0.656243852 0.85607947 20 32432880 32432985 106 + 1.050 1.007 -0.159
ENSG00000171456 E055 45.4034850 0.0003330357 0.172869001 0.44586489 20 32433284 32433917 634 + 1.616 1.676 0.204
ENSG00000171456 E056 1.0908193 0.0342950268 0.118836142 0.36433086 20 32433918 32434431 514 + 0.448 0.203 -1.595
ENSG00000171456 E057 8.7655161 0.0104130711 0.767296758 0.90988171 20 32434432 32434581 150 + 0.960 0.990 0.110
ENSG00000171456 E058 256.9004719 0.0001917381 0.116772975 0.36054692 20 32434582 32438429 3848 + 2.412 2.390 -0.074
ENSG00000171456 E059 60.4342246 0.0002629048 0.286357763 0.57999147 20 32438430 32439323 894 + 1.751 1.791 0.135

Help

Please Click HERE to learn more details about the results from DEXseq.