ENSG00000171566

1 Isoform Switch

Summary Plot

Only the isoforms with fraction > 5% are shown below.

  • Note:

    • About the Coding Potential: Please check the spreadsheet in the “Results” tag to confirm the coding potential. The above figure only show the predicted coding potential. The “gene_biotype” in the result spreadsheet is from the database record. Therefore, if you find conflicts between “gene_biotype” and “codingPotential”, please trust the “gene_biotype”.

    • Notes on IDR and IDR_w_binding: As the prediction of Intrinsically Disordered Regions (IDR) and Intrinsically Disordered Binding Regions (IDBR) are done by two different tools we require two things to annotate the Intrinsically Disordered Binding Regions (IDBR). Firstly the IDBR (predicted by ANCHOR2) must be a region of at least 15 amino acids (after the smoothing). Secondly the fraction of the IDBR which overlaps the IDR predictions (done by IUPred3, again after smoothing) must be at least 80%. When that is the case the IDR type will be annotated as “IDR_w_binding_region” instead of just “IDR”. The current default parameters have not been rigorously tested and should be considered experimental.

    • For the function of any other domain, please Click HERE to search it through Pfam database.

Results

isoform_id gene_id condition_1 condition_2 gene_name gene_biotype iso_biotype gene_overall_mean gene_value_1 gene_value_2 gene_stderr_1 gene_stderr_2 gene_log2_fold_change iso_overall_mean iso_value_1 iso_value_2 iso_stderr_1 iso_stderr_2 iso_log2_fold_change IF_overall IF1 IF2 dIF isoform_switch_q_value gene_switch_q_value PTC codingPotential
ENST00000302078 ENSG00000171566 No_inf pgKDN_inf PLRG1 protein_coding protein_coding 60.02254 52.45772 63.55542 2.026488 4.122718 0.2768122 19.800226 14.566733 23.202696 0.5274937 0.4749647 0.67124667 0.33190000 0.278750 0.371675 0.092925 0.51128070 0.01134614 FALSE TRUE
ENST00000499023 ENSG00000171566 No_inf pgKDN_inf PLRG1 protein_coding protein_coding 60.02254 52.45772 63.55542 2.026488 4.122718 0.2768122 3.881027 3.923579 4.704787 0.3560768 0.3641600 0.26135004 0.06660833 0.075075 0.075125 0.000050 1.00000000 0.01134614 FALSE TRUE
ENST00000506627 ENSG00000171566 No_inf pgKDN_inf PLRG1 protein_coding nonsense_mediated_decay 60.02254 52.45772 63.55542 2.026488 4.122718 0.2768122 5.688810 10.369497 1.594152 1.5840455 1.5941519 -2.69385384 0.09907500 0.195800 0.024900 -0.170900 0.01134614 0.01134614 TRUE FALSE
ENST00000509975 ENSG00000171566 No_inf pgKDN_inf PLRG1 protein_coding nonsense_mediated_decay 60.02254 52.45772 63.55542 2.026488 4.122718 0.2768122 5.064948 3.040524 8.057717 1.5201947 2.2846682 1.40310347 0.08101667 0.059350 0.123075 0.063725 0.62891395 0.01134614 FALSE FALSE
ENST00000512719 ENSG00000171566 No_inf pgKDN_inf PLRG1 protein_coding retained_intron 60.02254 52.45772 63.55542 2.026488 4.122718 0.2768122 4.102855 3.483911 3.588788 0.6124061 1.5539782 0.04266832 0.06802500 0.066950 0.056125 -0.010825 0.85396896 0.01134614 FALSE TRUE
ENST00000512773 ENSG00000171566 No_inf pgKDN_inf PLRG1 protein_coding retained_intron 60.02254 52.45772 63.55542 2.026488 4.122718 0.2768122 13.552650 10.944816 15.162859 0.9858013 2.2879584 0.46992777 0.22425833 0.207400 0.236550 0.029150 0.85861809 0.01134614   FALSE
  • Note:
    • The comparisons made can be identified as “from ‘condition_1’ to ‘condition_2’”, meaning ‘condition_1’ is considered the ground state and ‘condition_2’ the changed state. This also means that a positive dIF value indicates that the isoform usage is increased in ‘condition_2’ compared to ‘condition_1’. Since the ‘isoformFeatures’ entry is the most relevant part of the switchAnalyzeRlist object, the most-used standard methods have also been implemented to work directly on isoformFeatures.

Help

Please Click HERE to learn more details about the results of IsoformSwitchAnalyzeR.

2 Differential Exon Usage

Counts

All exons whithin this gene region are shown and numbering below.

Expression

All exons whithin this gene region are shown and numbering below.

Splicing

All exons whithin this gene region are shown and numbering below.

Transcripts

All isoforms whithin this gene region are shown below.

Results

groupID featureID exonBaseMean dispersion pvalue padj seqnames start end width strand pgKDN.inf No.inf log2fold_No.inf_pgKDN.inf
ENSG00000171566 E001 26.6530529 0.0027866011 0.919532214 0.97492101 4 154535005 154536431 1427 - 1.438 1.446 0.030
ENSG00000171566 E002 7.3770516 0.0020278669 0.172616007 0.44540579 4 154536432 154536520 89 - 0.850 0.988 0.522
ENSG00000171566 E003 10.8478803 0.0013897892 0.019991672 0.12694029 4 154536521 154536599 79 - 0.963 1.164 0.734
ENSG00000171566 E004 10.4227481 0.0013907452 0.467476952 0.73581067 4 154536600 154536618 19 - 1.024 1.089 0.237
ENSG00000171566 E005 26.6420240 0.0005136425 0.866127839 0.95386721 4 154536619 154536744 126 - 1.445 1.438 -0.024
ENSG00000171566 E006 46.2551935 0.0003296066 0.574585320 0.80952404 4 154537286 154537479 194 - 1.661 1.688 0.090
ENSG00000171566 E007 1.2212677 0.0125570759 0.889750806 0.96327959 4 154537480 154537542 63 - 0.336 0.358 0.136
ENSG00000171566 E008 32.0219742 0.0005116308 0.972769620 0.99491389 4 154537969 154538082 114 - 1.518 1.519 0.003
ENSG00000171566 E009 17.3676473 0.0105016513 0.769648170 0.91105073 4 154538083 154538108 26 - 1.251 1.278 0.095
ENSG00000171566 E010 0.0000000       4 154539014 154539104 91 -      
ENSG00000171566 E011 33.4685433 0.0005031862 0.157626707 0.42425217 4 154539105 154539213 109 - 1.500 1.573 0.252
ENSG00000171566 E012 33.2864073 0.0089240862 0.081745529 0.29412030 4 154539951 154540053 103 - 1.477 1.588 0.381
ENSG00000171566 E013 0.6077713 0.0184722856 0.728210954 0.89162818 4 154540054 154540272 219 - 0.231 0.180 -0.450
ENSG00000171566 E014 28.5758907 0.0005307296 0.252693041 0.54411796 4 154540594 154540670 77 - 1.438 1.502 0.222
ENSG00000171566 E015 17.6041359 0.0009008249 0.887876819 0.96249596 4 154540671 154540695 25 - 1.273 1.266 -0.025
ENSG00000171566 E016 36.9746972 0.0005286711 0.298797493 0.59178176 4 154540785 154540934 150 - 1.602 1.555 -0.161
ENSG00000171566 E017 0.1187032 0.0117929580 0.586905607   4 154540935 154540936 2 - 0.091 0.000 -9.758
ENSG00000171566 E018 1.0061699 0.0117191058 0.019489302 0.12494188 4 154541958 154542186 229 - 0.091 0.446 2.943
ENSG00000171566 E019 14.9429531 0.0009308769 0.049751778 0.22003977 4 154542187 154542230 44 - 1.268 1.124 -0.508
ENSG00000171566 E020 13.3020550 0.0011291754 0.001379277 0.01918957 4 154542231 154542279 49 - 1.262 1.010 -0.904
ENSG00000171566 E021 16.0062313 0.0008750632 0.774950028 0.91353804 4 154544445 154544546 102 - 1.239 1.221 -0.063
ENSG00000171566 E022 8.3495464 0.0021685037 0.401679713 0.68478457 4 154545836 154545852 17 - 0.928 1.010 0.305
ENSG00000171566 E023 13.8781414 0.0010305609 0.189155309 0.46774909 4 154545853 154545923 71 - 1.119 1.221 0.366
ENSG00000171566 E024 2.2574875 0.0073234279 0.001969952 0.02526691 4 154545924 154546122 199 - 0.231 0.686 2.457
ENSG00000171566 E025 11.1425481 0.0019640491 0.603525869 0.82699604 4 154546123 154546149 27 - 1.061 1.107 0.167
ENSG00000171566 E026 15.4859481 0.0009062536 0.400344261 0.68382782 4 154546150 154546213 64 - 1.245 1.187 -0.207
ENSG00000171566 E027 4.8373052 0.1691595827 0.102613750 0.33489377 4 154546543 154547010 468 - 0.606 0.885 1.134
ENSG00000171566 E028 12.5243055 0.0011623682 0.152315138 0.41622154 4 154547011 154547037 27 - 1.183 1.071 -0.403
ENSG00000171566 E029 12.4094740 0.0011801607 0.179713235 0.45495727 4 154547038 154547064 27 - 1.176 1.071 -0.379
ENSG00000171566 E030 0.1176306 0.0117406481 0.586938520   4 154547482 154547710 229 - 0.091 0.000 -9.758
ENSG00000171566 E031 27.7571012 0.0019074698 0.091729392 0.31449577 4 154547711 154547853 143 - 1.503 1.409 -0.324
ENSG00000171566 E032 23.1042604 0.0006257866 0.029034249 0.15983803 4 154548829 154548935 107 - 1.441 1.312 -0.450
ENSG00000171566 E033 0.2352613 0.2224197936 0.323339959   4 154549053 154549141 89 - 0.166 0.000 -10.758
ENSG00000171566 E034 0.0000000       4 154549664 154549772 109 -      
ENSG00000171566 E035 14.8647880 0.0009487595 0.249681966 0.54064345 4 154550300 154550400 101 - 1.239 1.157 -0.293

Help

Please Click HERE to learn more details about the results from DEXseq.