ENSG00000171603

1 Isoform Switch

Summary Plot

Only the isoforms with fraction > 5% are shown below.

  • Note:

    • About the Coding Potential: Please check the spreadsheet in the “Results” tag to confirm the coding potential. The above figure only show the predicted coding potential. The “gene_biotype” in the result spreadsheet is from the database record. Therefore, if you find conflicts between “gene_biotype” and “codingPotential”, please trust the “gene_biotype”.

    • Notes on IDR and IDR_w_binding: As the prediction of Intrinsically Disordered Regions (IDR) and Intrinsically Disordered Binding Regions (IDBR) are done by two different tools we require two things to annotate the Intrinsically Disordered Binding Regions (IDBR). Firstly the IDBR (predicted by ANCHOR2) must be a region of at least 15 amino acids (after the smoothing). Secondly the fraction of the IDBR which overlaps the IDR predictions (done by IUPred3, again after smoothing) must be at least 80%. When that is the case the IDR type will be annotated as “IDR_w_binding_region” instead of just “IDR”. The current default parameters have not been rigorously tested and should be considered experimental.

    • For the function of any other domain, please Click HERE to search it through Pfam database.

Results

isoform_id gene_id condition_1 condition_2 gene_name gene_biotype iso_biotype gene_overall_mean gene_value_1 gene_value_2 gene_stderr_1 gene_stderr_2 gene_log2_fold_change iso_overall_mean iso_value_1 iso_value_2 iso_stderr_1 iso_stderr_2 iso_log2_fold_change IF_overall IF1 IF2 dIF isoform_switch_q_value gene_switch_q_value PTC codingPotential
ENST00000435891 ENSG00000171603 No_inf pgKDN_inf CLSTN1 protein_coding protein_coding 84.99338 92.3756 78.94097 1.222057 1.132865 -0.226711 37.21936 39.103507 33.05234 1.8903254 0.582394 -0.2424780 0.4383417 0.423625 0.41905 -0.004575 1.0000000000 0.0007797242 FALSE TRUE
ENST00000477264 ENSG00000171603 No_inf pgKDN_inf CLSTN1 protein_coding protein_coding_CDS_not_defined 84.99338 92.3756 78.94097 1.222057 1.132865 -0.226711 27.08480 38.967598 19.88368 1.5238988 1.808312 -0.9703349 0.3133167 0.421625 0.25125 -0.170375 0.0090577850 0.0007797242 FALSE TRUE
MSTRG.211.3 ENSG00000171603 No_inf pgKDN_inf CLSTN1 protein_coding   84.99338 92.3756 78.94097 1.222057 1.132865 -0.226711 16.22358 8.938479 21.34122 0.8617565 2.029798 1.2546043 0.1957583 0.096550 0.27095 0.174400 0.0007797242 0.0007797242 FALSE TRUE
  • Note:
    • The comparisons made can be identified as “from ‘condition_1’ to ‘condition_2’”, meaning ‘condition_1’ is considered the ground state and ‘condition_2’ the changed state. This also means that a positive dIF value indicates that the isoform usage is increased in ‘condition_2’ compared to ‘condition_1’. Since the ‘isoformFeatures’ entry is the most relevant part of the switchAnalyzeRlist object, the most-used standard methods have also been implemented to work directly on isoformFeatures.

Help

Please Click HERE to learn more details about the results of IsoformSwitchAnalyzeR.

2 Differential Exon Usage

Counts

All exons whithin this gene region are shown and numbering below.

Expression

All exons whithin this gene region are shown and numbering below.

Splicing

All exons whithin this gene region are shown and numbering below.

Transcripts

All isoforms whithin this gene region are shown below.

Results

groupID featureID exonBaseMean dispersion pvalue padj seqnames start end width strand pgKDN.inf No.inf log2fold_No.inf_pgKDN.inf
ENSG00000171603 E001 0.0000000       1 9728926 9729026 101 -      
ENSG00000171603 E002 0.0000000       1 9729027 9729027 1 -      
ENSG00000171603 E003 809.5388747 4.880149e-05 8.616942e-18 1.904697e-15 1 9729028 9730705 1678 - 2.868 2.936 0.227
ENSG00000171603 E004 1.1165031 2.906970e-02 4.247827e-01 7.039773e-01 1 9731122 9731205 84 - 0.251 0.376 0.816
ENSG00000171603 E005 77.2295294 2.248894e-04 3.504178e-01 6.406588e-01 1 9731206 9731390 185 - 1.909 1.876 -0.111
ENSG00000171603 E006 58.0741432 3.179615e-04 9.823796e-01 9.986626e-01 1 9731761 9731896 136 - 1.770 1.768 -0.007
ENSG00000171603 E007 70.6325578 3.192714e-03 7.972084e-01 9.234475e-01 1 9733401 9733546 146 - 1.848 1.857 0.032
ENSG00000171603 E008 79.4892781 2.757706e-04 5.090091e-01 7.670764e-01 1 9733972 9734142 171 - 1.892 1.913 0.071
ENSG00000171603 E009 95.9445465 1.618770e-04 8.069194e-01 9.288052e-01 1 9734948 9735174 227 - 1.989 1.981 -0.029
ENSG00000171603 E010 69.7111921 2.085474e-04 2.293866e-01 5.180435e-01 1 9735467 9735615 149 - 1.871 1.827 -0.148
ENSG00000171603 E011 63.8440923 9.234088e-04 7.887268e-04 1.247118e-02 1 9735885 9736042 158 - 1.877 1.746 -0.444
ENSG00000171603 E012 2.5718662 6.150137e-03 9.469520e-01 9.858971e-01 1 9737498 9737554 57 - 0.557 0.547 -0.046
ENSG00000171603 E013 59.5685274 7.004466e-03 4.610813e-01 7.320564e-01 1 9741094 9741256 163 - 1.802 1.761 -0.137
ENSG00000171603 E014 51.4403021 4.152720e-03 9.053546e-01 9.697122e-01 1 9743884 9744005 122 - 1.715 1.720 0.016
ENSG00000171603 E015 75.7941091 5.359718e-03 5.930596e-01 8.205766e-01 1 9744395 9744643 249 - 1.871 1.893 0.074
ENSG00000171603 E016 0.2356421 1.566879e-02 2.026901e-01   1 9746889 9747012 124 - 0.182 0.000 -10.521
ENSG00000171603 E017 17.8546779 3.672278e-02 5.871225e-01 8.168800e-01 1 9749461 9749487 27 - 1.307 1.244 -0.222
ENSG00000171603 E018 51.2046133 2.443813e-03 2.929562e-02 1.606865e-01 1 9749488 9749646 159 - 1.768 1.667 -0.342
ENSG00000171603 E019 47.2968774 3.102705e-04 2.466692e-04 4.973404e-03 1 9749764 9749913 150 - 1.762 1.603 -0.543
ENSG00000171603 E020 0.0000000       1 9749914 9750167 254 -      
ENSG00000171603 E021 47.6383718 3.425138e-04 4.265370e-08 2.690625e-06 1 9751473 9751681 209 - 1.800 1.561 -0.812
ENSG00000171603 E022 35.0457084 4.625968e-03 4.555028e-04 8.124038e-03 1 9755114 9755309 196 - 1.654 1.452 -0.690
ENSG00000171603 E023 0.0000000       1 9756481 9756510 30 -      
ENSG00000171603 E024 15.6209878 3.413364e-03 1.444701e-04 3.203886e-03 1 9773272 9773394 123 - 1.355 1.063 -1.035
ENSG00000171603 E025 15.6129909 2.743040e-03 2.793926e-05 8.167350e-04 1 9823643 9823984 342 - 1.365 1.046 -1.134

Help

Please Click HERE to learn more details about the results from DEXseq.