ENSG00000171606

1 Isoform Switch

Summary Plot

Only the isoforms with fraction > 5% are shown below.

  • Note:

    • About the Coding Potential: Please check the spreadsheet in the “Results” tag to confirm the coding potential. The above figure only show the predicted coding potential. The “gene_biotype” in the result spreadsheet is from the database record. Therefore, if you find conflicts between “gene_biotype” and “codingPotential”, please trust the “gene_biotype”.

    • Notes on IDR and IDR_w_binding: As the prediction of Intrinsically Disordered Regions (IDR) and Intrinsically Disordered Binding Regions (IDBR) are done by two different tools we require two things to annotate the Intrinsically Disordered Binding Regions (IDBR). Firstly the IDBR (predicted by ANCHOR2) must be a region of at least 15 amino acids (after the smoothing). Secondly the fraction of the IDBR which overlaps the IDR predictions (done by IUPred3, again after smoothing) must be at least 80%. When that is the case the IDR type will be annotated as “IDR_w_binding_region” instead of just “IDR”. The current default parameters have not been rigorously tested and should be considered experimental.

    • For the function of any other domain, please Click HERE to search it through Pfam database.

Results

isoform_id gene_id condition_1 condition_2 gene_name gene_biotype iso_biotype gene_overall_mean gene_value_1 gene_value_2 gene_stderr_1 gene_stderr_2 gene_log2_fold_change iso_overall_mean iso_value_1 iso_value_2 iso_stderr_1 iso_stderr_2 iso_log2_fold_change IF_overall IF1 IF2 dIF isoform_switch_q_value gene_switch_q_value PTC codingPotential
ENST00000326804 ENSG00000171606 No_inf pgKDN_inf ZNF274 protein_coding protein_coding 12.91381 8.904948 14.126 0.371812 0.7192601 0.6650761 6.0589497 3.7378689 8.1221545 1.28145233 1.0952067 1.1175672 0.45807500 0.412775 0.567725 0.154950 8.273570e-01 2.555145e-06 FALSE TRUE
ENST00000345813 ENSG00000171606 No_inf pgKDN_inf ZNF274 protein_coding protein_coding 12.91381 8.904948 14.126 0.371812 0.7192601 0.6650761 0.2477848 0.7433545 0.0000000 0.15310864 0.0000000 -6.2352569 0.02825000 0.084750 0.000000 -0.084750 1.374628e-02 2.555145e-06 FALSE TRUE
ENST00000424679 ENSG00000171606 No_inf pgKDN_inf ZNF274 protein_coding protein_coding 12.91381 8.904948 14.126 0.371812 0.7192601 0.6650761 1.7096974 0.3961546 0.0000000 0.39615462 0.0000000 -5.3439571 0.11959167 0.047850 0.000000 -0.047850 8.270679e-01 2.555145e-06 FALSE TRUE
ENST00000594248 ENSG00000171606 No_inf pgKDN_inf ZNF274 protein_coding retained_intron 12.91381 8.904948 14.126 0.371812 0.7192601 0.6650761 0.6122382 0.6737706 0.4966299 0.15841825 0.1037896 -0.4325804 0.05119167 0.076125 0.035300 -0.040825 7.870125e-01 2.555145e-06   FALSE
ENST00000595146 ENSG00000171606 No_inf pgKDN_inf ZNF274 protein_coding retained_intron 12.91381 8.904948 14.126 0.371812 0.7192601 0.6650761 1.9531781 1.8824296 1.4987104 0.05314176 0.1014170 -0.3269237 0.15908333 0.212075 0.107750 -0.104325 4.861298e-01 2.555145e-06 FALSE TRUE
ENST00000610905 ENSG00000171606 No_inf pgKDN_inf ZNF274 protein_coding protein_coding 12.91381 8.904948 14.126 0.371812 0.7192601 0.6650761 0.4494113 0.9203181 0.0000000 0.92031811 0.0000000 -6.5396522 0.04550833 0.111175 0.000000 -0.111175 8.338935e-01 2.555145e-06 FALSE TRUE
ENST00000617501 ENSG00000171606 No_inf pgKDN_inf ZNF274 protein_coding protein_coding 12.91381 8.904948 14.126 0.371812 0.7192601 0.6650761 1.5384693 0.0000000 4.0085101 0.00000000 0.3110359 8.6505169 0.11053333 0.000000 0.289250 0.289250 2.555145e-06 2.555145e-06 FALSE TRUE
MSTRG.15753.7 ENSG00000171606 No_inf pgKDN_inf ZNF274 protein_coding   12.91381 8.904948 14.126 0.371812 0.7192601 0.6650761 0.1836840 0.5510520 0.0000000 0.55105197 0.0000000 -5.8100625 0.01844167 0.055325 0.000000 -0.055325 8.229857e-01 2.555145e-06 FALSE FALSE
  • Note:
    • The comparisons made can be identified as “from ‘condition_1’ to ‘condition_2’”, meaning ‘condition_1’ is considered the ground state and ‘condition_2’ the changed state. This also means that a positive dIF value indicates that the isoform usage is increased in ‘condition_2’ compared to ‘condition_1’. Since the ‘isoformFeatures’ entry is the most relevant part of the switchAnalyzeRlist object, the most-used standard methods have also been implemented to work directly on isoformFeatures.

Help

Please Click HERE to learn more details about the results of IsoformSwitchAnalyzeR.

2 Differential Exon Usage

Counts

All exons whithin this gene region are shown and numbering below.

Expression

All exons whithin this gene region are shown and numbering below.

Splicing

All exons whithin this gene region are shown and numbering below.

Transcripts

All isoforms whithin this gene region are shown below.

Results

groupID featureID exonBaseMean dispersion pvalue padj seqnames start end width strand pgKDN.inf No.inf log2fold_No.inf_pgKDN.inf
ENSG00000171606 E001 0.0000000       19 58183029 58183060 32 +      
ENSG00000171606 E002 0.1265070 0.0123241937 3.684204e-01   19 58183061 58183062 2 + 0.000 0.112 9.861
ENSG00000171606 E003 0.2441377 0.0161555581 7.751599e-01   19 58183063 58183071 9 + 0.080 0.112 0.534
ENSG00000171606 E004 0.2441377 0.0161555581 7.751599e-01   19 58183072 58183086 15 + 0.080 0.112 0.534
ENSG00000171606 E005 0.3712740 0.0169420500 3.806165e-01   19 58183087 58183108 22 + 0.080 0.201 1.534
ENSG00000171606 E006 1.3236563 0.0333357686 3.619567e-01 6.513005e-01 19 58183109 58183240 132 + 0.420 0.275 -0.881
ENSG00000171606 E007 1.7972152 0.0077619135 8.704101e-02 3.057490e-01 19 58183241 58183334 94 + 0.537 0.275 -1.466
ENSG00000171606 E008 0.7076830 0.0134382379 2.883135e-02 1.591055e-01 19 58183335 58183393 59 + 0.346 0.000 -14.017
ENSG00000171606 E009 0.2357071 0.0157065321 3.957964e-01   19 58183394 58183399 6 + 0.148 0.000 -12.720
ENSG00000171606 E010 0.4795651 0.0179248889 5.281599e-01   19 58183400 58183426 27 + 0.207 0.112 -1.051
ENSG00000171606 E011 0.9675607 0.0138281604 8.467721e-01 9.456456e-01 19 58183427 58183442 16 + 0.305 0.275 -0.203
ENSG00000171606 E012 0.2533610 0.0160883878 1.398045e-01   19 58183443 58183453 11 + 0.000 0.201 12.677
ENSG00000171606 E013 0.2533610 0.0160883878 1.398045e-01   19 58183454 58183493 40 + 0.000 0.201 12.677
ENSG00000171606 E014 0.4981279 0.0158711170 1.734019e-01   19 58183494 58183596 103 + 0.080 0.275 2.119
ENSG00000171606 E015 1.4612145 0.0087672421 9.578519e-01 9.899059e-01 19 58183597 58183920 324 + 0.385 0.393 0.049
ENSG00000171606 E016 2.2825005 0.0069494109 1.870338e-01 4.648610e-01 19 58183921 58183998 78 + 0.585 0.393 -0.951
ENSG00000171606 E017 0.7439674 0.0142942468 2.070051e-01 4.906227e-01 19 58183999 58184846 848 + 0.148 0.338 1.534
ENSG00000171606 E018 0.2458395 0.0162944243 7.744233e-01   19 58185474 58185696 223 + 0.080 0.112 0.534
ENSG00000171606 E019 0.0000000       19 58185697 58185711 15 +      
ENSG00000171606 E020 4.3684411 0.0061112116 8.048048e-01 9.277040e-01 19 58185712 58185838 127 + 0.738 0.710 -0.118
ENSG00000171606 E021 0.7335179 0.0145647017 6.564294e-01 8.561791e-01 19 58185839 58186176 338 + 0.207 0.275 0.534
ENSG00000171606 E022 4.0930917 0.0035140618 7.905157e-02 2.883322e-01 19 58186947 58187042 96 + 0.784 0.562 -0.940
ENSG00000171606 E023 0.0000000       19 58202227 58202468 242 +      
ENSG00000171606 E024 15.5362673 0.0009478367 4.154424e-01 6.955508e-01 19 58206720 58207202 483 + 1.237 1.180 -0.203
ENSG00000171606 E025 14.0825513 0.0012469404 2.289370e-06 9.512702e-05 19 58208098 58209960 1863 + 0.989 1.341 1.257
ENSG00000171606 E026 5.5746763 0.0038335099 3.968260e-01 6.813362e-01 19 58209961 58210073 113 + 0.851 0.757 -0.373
ENSG00000171606 E027 9.4087609 0.0193454186 3.623889e-01 6.516114e-01 19 58210074 58211559 1486 + 0.970 1.065 0.347
ENSG00000171606 E028 7.5921096 0.0020900798 4.025783e-02 1.945404e-01 19 58211560 58211686 127 + 1.007 0.799 -0.788
ENSG00000171606 E029 92.9242239 0.0002350150 6.198425e-01 8.354931e-01 19 58212161 58213562 1402 + 1.972 1.962 -0.032

Help

Please Click HERE to learn more details about the results from DEXseq.