ENSG00000171608

1 Isoform Switch

Summary Plot

Only the isoforms with fraction > 5% are shown below.

  • Note:

    • About the Coding Potential: Please check the spreadsheet in the “Results” tag to confirm the coding potential. The above figure only show the predicted coding potential. The “gene_biotype” in the result spreadsheet is from the database record. Therefore, if you find conflicts between “gene_biotype” and “codingPotential”, please trust the “gene_biotype”.

    • Notes on IDR and IDR_w_binding: As the prediction of Intrinsically Disordered Regions (IDR) and Intrinsically Disordered Binding Regions (IDBR) are done by two different tools we require two things to annotate the Intrinsically Disordered Binding Regions (IDBR). Firstly the IDBR (predicted by ANCHOR2) must be a region of at least 15 amino acids (after the smoothing). Secondly the fraction of the IDBR which overlaps the IDR predictions (done by IUPred3, again after smoothing) must be at least 80%. When that is the case the IDR type will be annotated as “IDR_w_binding_region” instead of just “IDR”. The current default parameters have not been rigorously tested and should be considered experimental.

    • For the function of any other domain, please Click HERE to search it through Pfam database.

Results

isoform_id gene_id condition_1 condition_2 gene_name gene_biotype iso_biotype gene_overall_mean gene_value_1 gene_value_2 gene_stderr_1 gene_stderr_2 gene_log2_fold_change iso_overall_mean iso_value_1 iso_value_2 iso_stderr_1 iso_stderr_2 iso_log2_fold_change IF_overall IF1 IF2 dIF isoform_switch_q_value gene_switch_q_value PTC codingPotential
ENST00000377346 ENSG00000171608 No_inf pgKDN_inf PIK3CD protein_coding protein_coding 19.62042 20.99257 18.32615 0.5222773 0.8061124 -0.1958756 6.4727985 3.4177767 7.8850068 3.4177767 0.9811030 1.203667 0.33401667 0.158275 0.426450 0.268175 0.0451631 0.0451631 FALSE TRUE
ENST00000698709 ENSG00000171608 No_inf pgKDN_inf PIK3CD protein_coding protein_coding 19.62042 20.99257 18.32615 0.5222773 0.8061124 -0.1958756 0.4838634 1.4515902 0.0000000 0.8428648 0.0000000 -7.191395 0.02270833 0.068125 0.000000 -0.068125 0.5162937 0.0451631 FALSE TRUE
ENST00000698710 ENSG00000171608 No_inf pgKDN_inf PIK3CD protein_coding protein_coding 19.62042 20.99257 18.32615 0.5222773 0.8061124 -0.1958756 2.0655162 2.2502637 0.8369845 1.4443651 0.8369845 -1.416084 0.10186667 0.105625 0.041700 -0.063925 0.8281822 0.0451631 FALSE TRUE
ENST00000698712 ENSG00000171608 No_inf pgKDN_inf PIK3CD protein_coding protein_coding 19.62042 20.99257 18.32615 0.5222773 0.8061124 -0.1958756 5.4092985 4.8198448 7.4065993 1.9213764 0.8281354 0.618781 0.28405833 0.235250 0.412650 0.177400 0.6800003 0.0451631 FALSE TRUE
ENST00000698719 ENSG00000171608 No_inf pgKDN_inf PIK3CD protein_coding retained_intron 19.62042 20.99257 18.32615 0.5222773 0.8061124 -0.1958756 2.3734180 4.3726424 1.2138375 0.4501924 0.3595214 -1.840389 0.11694167 0.207725 0.064475 -0.143250 0.1230199 0.0451631 TRUE TRUE
MSTRG.207.5 ENSG00000171608 No_inf pgKDN_inf PIK3CD protein_coding   19.62042 20.99257 18.32615 0.5222773 0.8061124 -0.1958756 0.3329471 0.9988414 0.0000000 0.9988414 0.0000000 -6.656556 0.01679167 0.050375 0.000000 -0.050375 0.8675526 0.0451631 FALSE TRUE
  • Note:
    • The comparisons made can be identified as “from ‘condition_1’ to ‘condition_2’”, meaning ‘condition_1’ is considered the ground state and ‘condition_2’ the changed state. This also means that a positive dIF value indicates that the isoform usage is increased in ‘condition_2’ compared to ‘condition_1’. Since the ‘isoformFeatures’ entry is the most relevant part of the switchAnalyzeRlist object, the most-used standard methods have also been implemented to work directly on isoformFeatures.

Help

Please Click HERE to learn more details about the results of IsoformSwitchAnalyzeR.

2 Differential Exon Usage

Counts

All exons whithin this gene region are shown and numbering below.

Expression

All exons whithin this gene region are shown and numbering below.

Splicing

All exons whithin this gene region are shown and numbering below.

Transcripts

All isoforms whithin this gene region are shown below.

Results

groupID featureID exonBaseMean dispersion pvalue padj seqnames start end width strand pgKDN.inf No.inf log2fold_No.inf_pgKDN.inf
ENSG00000171608 E001 0.0000000       1 9629889 9629915 27 +      
ENSG00000171608 E002 0.0000000       1 9629973 9630137 165 +      
ENSG00000171608 E003 0.0000000       1 9630138 9630224 87 +      
ENSG00000171608 E004 0.1170040 0.0116132466 0.4678425396   1 9651731 9651731 1 + 0.101 0.000 -11.374
ENSG00000171608 E005 0.5952783 0.5522794737 0.4608776061 0.731979021 1 9651732 9651743 12 + 0.310 0.090 -2.187
ENSG00000171608 E006 0.5952783 0.5522794737 0.4608776061 0.731979021 1 9651744 9651747 4 + 0.310 0.090 -2.187
ENSG00000171608 E007 0.5952783 0.5522794737 0.4608776061 0.731979021 1 9651748 9651749 2 + 0.310 0.090 -2.187
ENSG00000171608 E008 0.8315471 0.0860820527 0.0473975825 0.213955575 1 9651750 9651768 19 + 0.410 0.090 -2.775
ENSG00000171608 E009 1.2125173 0.1018177257 0.4680515951 0.736402997 1 9651769 9651802 34 + 0.410 0.282 -0.775
ENSG00000171608 E010 0.4818909 0.0424610173 0.2617745805   1 9664596 9664758 163 + 0.252 0.090 -1.777
ENSG00000171608 E011 0.1271363 0.0123609298 0.6183215294   1 9688176 9688313 138 + 0.000 0.090 12.670
ENSG00000171608 E012 0.0000000       1 9689547 9689552 6 +      
ENSG00000171608 E013 0.0000000       1 9689553 9689569 17 +      
ENSG00000171608 E014 0.0000000       1 9689570 9689721 152 +      
ENSG00000171608 E015 2.0663725 0.0077680652 0.3172102622 0.610012775 1 9691467 9691493 27 + 0.558 0.416 -0.706
ENSG00000171608 E016 4.2933983 0.0037824696 0.8093226881 0.929636015 1 9691494 9691571 78 + 0.736 0.710 -0.109
ENSG00000171608 E017 0.3811266 0.0313177060 0.1354372525   1 9691675 9691946 272 + 0.000 0.227 14.106
ENSG00000171608 E018 0.4890333 0.0157545356 0.8904126313   1 9710105 9710197 93 + 0.183 0.164 -0.191
ENSG00000171608 E019 0.3617709 0.0164987766 0.5013131590   1 9710198 9710280 83 + 0.183 0.090 -1.191
ENSG00000171608 E020 0.1186381 0.0118050538 0.4676978808   1 9710335 9710423 89 + 0.101 0.000 -13.766
ENSG00000171608 E021 9.6304666 0.0014543155 0.0650180890 0.256853292 1 9710424 9710596 173 + 1.106 0.944 -0.596
ENSG00000171608 E022 14.1086121 0.0009568424 0.0052808902 0.051628860 1 9715541 9715769 229 + 1.280 1.071 -0.745
ENSG00000171608 E023 0.0000000       1 9715770 9715823 54 +      
ENSG00000171608 E024 0.0000000       1 9715841 9715848 8 +      
ENSG00000171608 E025 13.0956852 0.0010635179 0.3147928040 0.607660526 1 9715849 9716078 230 + 1.187 1.111 -0.272
ENSG00000171608 E026 0.8617580 0.0125793033 0.8458683294 0.945239982 1 9716079 9716241 163 + 0.252 0.282 0.224
ENSG00000171608 E027 0.4971544 0.0334627155 0.3937327736   1 9716242 9716275 34 + 0.101 0.227 1.394
ENSG00000171608 E028 1.0072420 0.0116926912 0.0416953057 0.198586596 1 9716276 9716439 164 + 0.101 0.416 2.616
ENSG00000171608 E029 12.7866995 0.0010998145 0.7858396016 0.917487334 1 9716440 9716619 180 + 1.124 1.148 0.087
ENSG00000171608 E030 1.1434109 0.0107740551 0.0019258640 0.024849175 1 9716620 9716958 339 + 0.000 0.486 15.577
ENSG00000171608 E031 9.2280458 0.0015424075 0.6630127609 0.859548345 1 9716959 9717063 105 + 0.984 1.026 0.157
ENSG00000171608 E032 5.9639754 0.0023822338 0.1411904553 0.399791906 1 9717064 9717108 45 + 0.920 0.764 -0.606
ENSG00000171608 E033 0.2537694 0.0160197682 0.2942364800   1 9717496 9717536 41 + 0.000 0.164 13.610
ENSG00000171608 E034 6.6011010 0.0022241378 0.4397736233 0.715658786 1 9717537 9717626 90 + 0.920 0.842 -0.298
ENSG00000171608 E035 0.1268540 0.0123311912 0.6183454829   1 9718069 9718158 90 + 0.000 0.090 12.671
ENSG00000171608 E036 3.6649483 0.0040081531 0.4614392570 0.732185759 1 9718694 9718705 12 + 0.715 0.624 -0.384
ENSG00000171608 E037 13.3307130 0.0010657983 0.3135631148 0.606741759 1 9718706 9718849 144 + 1.194 1.119 -0.271
ENSG00000171608 E038 10.9571120 0.0115299256 0.0911099325 0.313488894 1 9718850 9718915 66 + 1.156 0.997 -0.578
ENSG00000171608 E039 0.3804973 0.0159281009 0.1328070279   1 9718916 9719494 579 + 0.000 0.227 14.154
ENSG00000171608 E040 10.4967420 0.0110536357 0.2503844299 0.541468879 1 9719921 9720017 97 + 1.115 1.007 -0.393
ENSG00000171608 E041 9.6632127 0.0035578991 0.3522136359 0.642243906 1 9720112 9720242 131 + 1.069 0.987 -0.301
ENSG00000171608 E042 0.3723465 0.0165331126 0.6738139292   1 9720243 9720311 69 + 0.101 0.164 0.809
ENSG00000171608 E043 0.7537251 0.0132752010 0.1292952666 0.381456753 1 9720312 9720433 122 + 0.101 0.331 2.130
ENSG00000171608 E044 0.3816610 0.0240717059 0.1345693245   1 9720434 9720461 28 + 0.000 0.227 14.128
ENSG00000171608 E045 0.6361857 0.3078688688 0.0915908280 0.314260431 1 9720462 9720610 149 + 0.000 0.332 14.338
ENSG00000171608 E046 6.0130700 0.0023462274 0.9551150513 0.989059293 1 9720611 9720661 51 + 0.846 0.842 -0.015
ENSG00000171608 E047 3.0459757 0.0048068651 0.3496097813 0.639931854 1 9720742 9720744 3 + 0.669 0.546 -0.539
ENSG00000171608 E048 14.6507522 0.0027062194 0.1488266264 0.410915085 1 9720745 9720909 165 + 1.249 1.141 -0.384
ENSG00000171608 E049 0.0000000       1 9720910 9720993 84 +      
ENSG00000171608 E050 5.6359091 0.0045225419 0.6414269531 0.847740883 1 9721127 9721135 9 + 0.846 0.797 -0.191
ENSG00000171608 E051 11.1670227 0.0338560863 0.7693202086 0.910878251 1 9721136 9721248 113 + 1.097 1.071 -0.097
ENSG00000171608 E052 0.7360072 0.0785031748 0.8626681379 0.952585700 1 9721249 9721443 195 + 0.252 0.227 -0.192
ENSG00000171608 E053 5.6023199 0.0316213468 0.1492945975 0.411549933 1 9721444 9721491 48 + 0.907 0.729 -0.699
ENSG00000171608 E054 9.5455021 0.0014260154 0.4037871266 0.686608704 1 9721492 9721587 96 + 1.059 0.987 -0.265
ENSG00000171608 E055 0.9981182 0.3418344381 0.4857932353 0.749607797 1 9721588 9721760 173 + 0.183 0.375 1.392
ENSG00000171608 E056 11.3034153 0.0013197414 0.8643773080 0.953087577 1 9721761 9721860 100 + 1.079 1.095 0.060
ENSG00000171608 E057 16.4541311 0.0087115045 0.9755446208 0.995685778 1 9721975 9722153 179 + 1.236 1.243 0.024
ENSG00000171608 E058 15.0658922 0.0009273475 0.4973222067 0.757965582 1 9722244 9722356 113 + 1.229 1.182 -0.168
ENSG00000171608 E059 13.4688510 0.0130987063 0.6381233108 0.845753568 1 9722528 9722606 79 + 1.180 1.141 -0.139
ENSG00000171608 E060 24.6567554 0.0036419071 0.7409701570 0.897148601 1 9723125 9723292 168 + 1.417 1.399 -0.062
ENSG00000171608 E061 4.8703039 0.0029785374 0.0026566323 0.031485457 1 9723293 9723968 676 + 0.526 0.896 1.546
ENSG00000171608 E062 21.6744617 0.0007008536 0.2294787054 0.518070511 1 9723969 9724092 124 + 1.309 1.387 0.272
ENSG00000171608 E063 1.4822679 0.0104967232 0.7376717799 0.895907760 1 9724093 9724275 183 + 0.363 0.416 0.294
ENSG00000171608 E064 32.7942600 0.0004056503 0.8765452226 0.958140857 1 9724276 9724421 146 + 1.521 1.531 0.036
ENSG00000171608 E065 28.3624118 0.0004771942 0.9466381646 0.985769945 1 9724804 9724936 133 + 1.462 1.468 0.021
ENSG00000171608 E066 270.5539054 0.0001369130 0.0002477505 0.004991474 1 9726909 9729114 2206 + 2.400 2.456 0.185

Help

Please Click HERE to learn more details about the results from DEXseq.