ENSG00000171657

1 Isoform Switch

Summary Plot

Only the isoforms with fraction > 5% are shown below.

  • Note:

    • About the Coding Potential: Please check the spreadsheet in the “Results” tag to confirm the coding potential. The above figure only show the predicted coding potential. The “gene_biotype” in the result spreadsheet is from the database record. Therefore, if you find conflicts between “gene_biotype” and “codingPotential”, please trust the “gene_biotype”.

    • Notes on IDR and IDR_w_binding: As the prediction of Intrinsically Disordered Regions (IDR) and Intrinsically Disordered Binding Regions (IDBR) are done by two different tools we require two things to annotate the Intrinsically Disordered Binding Regions (IDBR). Firstly the IDBR (predicted by ANCHOR2) must be a region of at least 15 amino acids (after the smoothing). Secondly the fraction of the IDBR which overlaps the IDR predictions (done by IUPred3, again after smoothing) must be at least 80%. When that is the case the IDR type will be annotated as “IDR_w_binding_region” instead of just “IDR”. The current default parameters have not been rigorously tested and should be considered experimental.

    • For the function of any other domain, please Click HERE to search it through Pfam database.

Results

isoform_id gene_id condition_1 condition_2 gene_name gene_biotype iso_biotype gene_overall_mean gene_value_1 gene_value_2 gene_stderr_1 gene_stderr_2 gene_log2_fold_change iso_overall_mean iso_value_1 iso_value_2 iso_stderr_1 iso_stderr_2 iso_log2_fold_change IF_overall IF1 IF2 dIF isoform_switch_q_value gene_switch_q_value PTC codingPotential
ENST00000302548 ENSG00000171657 No_inf pgKDN_inf GPR82 protein_coding protein_coding 14.93511 8.775613 19.50179 0.4586381 0.4853105 1.151131 10.299869 6.3213010 13.455747 0.5416723 1.179042 1.088720 0.69571667 0.72110 0.69495 -0.02615 0.9948699 0.0107275 FALSE TRUE
ENST00000497180 ENSG00000171657 No_inf pgKDN_inf GPR82 protein_coding protein_coding_CDS_not_defined 14.93511 8.775613 19.50179 0.4586381 0.4853105 1.151131 0.651088 1.9532640 0.000000 0.7274344 0.000000 -7.617110 0.07288333 0.21865 0.00000 -0.21865 0.0107275 0.0107275   FALSE
MSTRG.29906.1 ENSG00000171657 No_inf pgKDN_inf GPR82 protein_coding   14.93511 8.775613 19.50179 0.4586381 0.4853105 1.151131 3.984153 0.5010479 6.046042 0.2909370 1.582366 3.566845 0.23140000 0.06025 0.30505 0.24480 0.2004024 0.0107275 TRUE TRUE
  • Note:
    • The comparisons made can be identified as “from ‘condition_1’ to ‘condition_2’”, meaning ‘condition_1’ is considered the ground state and ‘condition_2’ the changed state. This also means that a positive dIF value indicates that the isoform usage is increased in ‘condition_2’ compared to ‘condition_1’. Since the ‘isoformFeatures’ entry is the most relevant part of the switchAnalyzeRlist object, the most-used standard methods have also been implemented to work directly on isoformFeatures.

Help

Please Click HERE to learn more details about the results of IsoformSwitchAnalyzeR.

2 Differential Exon Usage

Counts

All exons whithin this gene region are shown and numbering below.

Expression

All exons whithin this gene region are shown and numbering below.

Splicing

All exons whithin this gene region are shown and numbering below.

Transcripts

All isoforms whithin this gene region are shown below.

Results

groupID featureID exonBaseMean dispersion pvalue padj seqnames start end width strand pgKDN.inf No.inf log2fold_No.inf_pgKDN.inf
ENSG00000171657 E001 1.687040 0.0082558104 0.868983864 0.95488787 X 41724153 41724180 28 + 0.418 0.394 -0.132
ENSG00000171657 E002 9.325334 0.0014997933 0.009927324 0.07987771 X 41724181 41724289 109 + 1.056 0.791 -1.003
ENSG00000171657 E003 8.301662 0.0101493929 0.583001144 0.81433116 X 41726773 41726843 71 + 0.959 0.904 -0.206
ENSG00000171657 E004 71.454406 0.0002692734 0.005209094 0.05112291 X 41726993 41728132 1140 + 1.857 1.768 -0.300
ENSG00000171657 E005 26.658994 0.0192990155 0.257328318 0.54956539 X 41728133 41728511 379 + 1.383 1.469 0.296
ENSG00000171657 E006 12.569341 0.0013395203 0.806798037 0.92875107 X 41728512 41728647 136 + 1.097 1.121 0.084
ENSG00000171657 E007 95.733253 0.0002150389 0.005659553 0.05414018 X 41728648 41730130 1483 + 1.932 2.003 0.241

Help

Please Click HERE to learn more details about the results from DEXseq.